GB1113569A - N-substituted amides of ª‡-acylamino-acrylic acids - Google Patents
N-substituted amides of ª‡-acylamino-acrylic acidsInfo
- Publication number
- GB1113569A GB1113569A GB5682666A GB5682666A GB1113569A GB 1113569 A GB1113569 A GB 1113569A GB 5682666 A GB5682666 A GB 5682666A GB 5682666 A GB5682666 A GB 5682666A GB 1113569 A GB1113569 A GB 1113569A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acylamino
- reacting
- acid
- acrylic acids
- substituted amides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
Abstract
Novel compounds of formula <FORM:1113569/C2/1> wherein R1 and R2 represent hydrogen atoms or unsubstituted or substituted alkyl, aryl or aralkyl groups, and R3 represents a tertiary amine linked through an alkylene group, and acid addition salts thereof, are prepared by reacting an azlactone of an a -acylamino-acrylic acid with an amine R3NH2, or by reacting an ester of the appropriate a -acylaminoacrylic acid with diamine, and, in either case, if desired, reacting the base obtained with an acid in the presence of a solvent.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DESC038215 | 1965-12-20 | ||
DESC039618 | 1966-10-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1113569A true GB1113569A (en) | 1968-05-15 |
Family
ID=25993340
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5682666A Expired GB1113569A (en) | 1965-12-20 | 1966-12-19 | N-substituted amides of ª‡-acylamino-acrylic acids |
Country Status (7)
Country | Link |
---|---|
AT (1) | AT277195B (en) |
BE (1) | BE690536A (en) |
DE (2) | DE1493184A1 (en) |
ES (1) | ES334530A1 (en) |
FR (1) | FR1511631A (en) |
GB (1) | GB1113569A (en) |
NL (1) | NL6617752A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8143446B2 (en) | 2005-05-12 | 2012-03-27 | Daiichi Sankyo Company, Limited | Substituted acrylamide derivative and pharmaceutical composition comprising the same |
-
1965
- 1965-12-20 DE DE19651493184 patent/DE1493184A1/en active Pending
-
1966
- 1966-10-03 DE DE19661620463 patent/DE1620463A1/en active Pending
- 1966-12-01 BE BE690536D patent/BE690536A/xx unknown
- 1966-12-15 ES ES334530A patent/ES334530A1/en not_active Expired
- 1966-12-16 NL NL6617752A patent/NL6617752A/xx unknown
- 1966-12-19 GB GB5682666A patent/GB1113569A/en not_active Expired
- 1966-12-20 FR FR88134A patent/FR1511631A/en not_active Expired
- 1966-12-20 AT AT1170066A patent/AT277195B/en not_active IP Right Cessation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8143446B2 (en) | 2005-05-12 | 2012-03-27 | Daiichi Sankyo Company, Limited | Substituted acrylamide derivative and pharmaceutical composition comprising the same |
US8497397B2 (en) | 2005-05-12 | 2013-07-30 | Daiichi Sankyo Company, Limited | Substituted acrylamide derivative and pharmaceutical composition comprising the same |
Also Published As
Publication number | Publication date |
---|---|
NL6617752A (en) | 1967-06-21 |
DE1620463A1 (en) | 1970-04-09 |
FR1511631A (en) | 1968-02-02 |
DE1493184A1 (en) | 1969-04-24 |
ES334530A1 (en) | 1968-02-16 |
AT277195B (en) | 1969-12-10 |
BE690536A (en) | 1967-06-01 |
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