GB1113492A - Chewable tablets comprising a penicillin antibiotic - Google Patents

Chewable tablets comprising a penicillin antibiotic

Info

Publication number
GB1113492A
GB1113492A GB20682/65A GB2068265A GB1113492A GB 1113492 A GB1113492 A GB 1113492A GB 20682/65 A GB20682/65 A GB 20682/65A GB 2068265 A GB2068265 A GB 2068265A GB 1113492 A GB1113492 A GB 1113492A
Authority
GB
United Kingdom
Prior art keywords
chewable tablets
gms
penicillin antibiotic
tablets
penicillin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20682/65A
Inventor
Alphonse P Granatek
Michael P Demurio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB1113492A publication Critical patent/GB1113492A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Abstract

1,113,492. tablets. BRISTOL-MYERS CO. 17 May, 1965 [20 May, 1964), No. 20682/65. Heading A5B. A chewable tablet comprises up to 0.25 grm. of α-aminobenzyl penicillin or an equivalent amount of a derrivative therof, e.g. the trihydrate from 0.30 to 0.40 gms. of mannitol and 0.001 to 0.003 gms. of a solid polyethylene glycol, e.g. of M.W. 6000 to 7500. Preferred formulations also include glycine, sodium cyclamate, sodium saccharin and magnesium stearate.
GB20682/65A 1964-05-20 1965-05-17 Chewable tablets comprising a penicillin antibiotic Expired GB1113492A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36899164A 1964-05-20 1964-05-20
US66529767A 1967-09-05 1967-09-05

Publications (1)

Publication Number Publication Date
GB1113492A true GB1113492A (en) 1968-05-15

Family

ID=31949833

Family Applications (2)

Application Number Title Priority Date Filing Date
GB20682/65A Expired GB1113492A (en) 1964-05-20 1965-05-17 Chewable tablets comprising a penicillin antibiotic
GB07313/71A Expired GB1248189A (en) 1964-05-20 1968-09-05 Chewable tablets comprising an antibacterial agent

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB07313/71A Expired GB1248189A (en) 1964-05-20 1968-09-05 Chewable tablets comprising an antibacterial agent

Country Status (4)

Country Link
US (1) US3459858A (en)
AT (1) AT282060B (en)
GB (2) GB1113492A (en)
SU (1) SU380002A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0396335A1 (en) * 1989-04-28 1990-11-07 Beecham Group p.l.c. Pharmaceutical formulation

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692896A (en) * 1968-06-14 1972-09-19 Isumura Juntendo Co Ltd Process for the preparation of water-soluble tablets
DE2347713C3 (en) * 1972-09-25 1980-03-06 Warner-Lambert Co., Morris Plains, N.J. (V.St.A.) Acetylsalicylic acid chewable tablet
KR890701104A (en) * 1987-05-27 1989-12-19 에지.지.제이.베르미렌, 에이.디.도우마 Rapidly Soluble Anhydrous Composition of β-lactam Antibiotic
WO2005011707A1 (en) * 2003-07-25 2005-02-10 Warner Chilcott Company, Inc. A doxycycline metal complex in a solid dosage form
JP5256425B2 (en) 2005-04-08 2013-08-07 リングアル コンセグナ ピーティーワイ エルティーディー Oral delivery system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145146A (en) * 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0396335A1 (en) * 1989-04-28 1990-11-07 Beecham Group p.l.c. Pharmaceutical formulation
US5225197A (en) * 1989-04-28 1993-07-06 Beecham Group Plc Pharmaceutical formulation

Also Published As

Publication number Publication date
AT282060B (en) 1970-06-10
GB1248189A (en) 1971-09-29
US3459858A (en) 1969-08-05
SU380002A3 (en) 1973-04-20

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