GB1086101A - New chromans and process for preparing same - Google Patents

New chromans and process for preparing same

Info

Publication number
GB1086101A
GB1086101A GB104666A GB104666A GB1086101A GB 1086101 A GB1086101 A GB 1086101A GB 104666 A GB104666 A GB 104666A GB 104666 A GB104666 A GB 104666A GB 1086101 A GB1086101 A GB 1086101A
Authority
GB
United Kingdom
Prior art keywords
acid addition
chromans
amino
chroman
carbon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB104666A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB1086101A publication Critical patent/GB1086101A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Abstract

The invention comprises 3-guanidino-chromans, acid addition salts thereof and their preparation by reaction of a 3-amino-chroman or an acid addition salt thereof with a compound of formula XN = CYZ, wherein Z is an optionally substituted amino group, Y is an etherified mercapto group and X is a hydrogen atom or a substituent or X and Y together with the carbon-nitrogen double bond form a carbon-nitrogen triple bond, or an acid addition salt thereof, followed if desired by N-substitution. 3-Amino-chroman is prepared by reaction of 3-chromonone with hydroxylamine hydrate to form 3-chromonoxime, and subjecting this to catalytic hydrogenation. The compounds of the invention have hypotensive activity and may be used in pharmaceutical or veterinary compositions in combination with a carrier, for example in forms suitable for oral or parenteral administration or in animal feeds.
GB104666A 1965-01-19 1966-01-10 New chromans and process for preparing same Expired GB1086101A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH74065 1965-01-19

Publications (1)

Publication Number Publication Date
GB1086101A true GB1086101A (en) 1967-10-04

Family

ID=4194095

Family Applications (1)

Application Number Title Priority Date Filing Date
GB104666A Expired GB1086101A (en) 1965-01-19 1966-01-10 New chromans and process for preparing same

Country Status (3)

Country Link
BE (1) BE675264A (en)
FR (1) FR1465838A (en)
GB (1) GB1086101A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans

Also Published As

Publication number Publication date
BE675264A (en) 1966-07-18
FR1465838A (en) 1967-01-13

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