GB1074084A - Dibenzocycloheptene compounds - Google Patents
Dibenzocycloheptene compoundsInfo
- Publication number
- GB1074084A GB1074084A GB35403/66A GB3540366A GB1074084A GB 1074084 A GB1074084 A GB 1074084A GB 35403/66 A GB35403/66 A GB 35403/66A GB 3540366 A GB3540366 A GB 3540366A GB 1074084 A GB1074084 A GB 1074084A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- formula
- alkyl
- radical
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
The invention comprises compounds of the Formula I, wherein R0 represents a C1- 6 alkyl radical, each of R11 and R111 represents a hydrogen atom or an alkyl, aryl or aralkyl radical and each of X and X1 represents a hydrogen or halogen atom or a C1- 6 alkyl, C2- 6 alkenyl, trifluoromethyl, hydroxyl, C1- 4 alkoxy, mercapto, C1- 4 alkylmercapto, C1- 4 alkylsulphonyl, sulphamoyl, C1- 4 alkylsulphamoyl, C2- 8 dialkylsulphamoyl radical; their preparation by reacting a compound of the Formula II with a cyanogen halide; and the conversion of compounds of the Formula I into compounds of the Formula III by alkaline hydrolysis. <FORM:1074084/C2/1> <FORM:1074084/C2/2> <FORM:1074084/C2/3>
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US296463A US3390179A (en) | 1963-07-22 | 1963-07-22 | Novel 10, 11-dihydro-10, 11-dihydroxy-(3-substituted aminopropylidene)-5h-dibenzo [a, d] cycloheptenes |
| US4847870A | 1970-06-22 | 1970-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1074084A true GB1074084A (en) | 1967-06-28 |
Family
ID=26726156
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB28412/64A Expired GB1074082A (en) | 1963-07-22 | 1964-07-09 | Dibenzocycloheptene compounds |
| GB35402/66A Expired GB1074083A (en) | 1963-07-22 | 1964-07-09 | Dibenzocycloheptene compounds |
| GB35404/66A Expired GB1074085A (en) | 1963-07-22 | 1964-07-09 | Dibenzocycloheptene compounds |
| GB35403/66A Expired GB1074084A (en) | 1963-07-22 | 1964-07-09 | Dibenzocycloheptene compounds |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB28412/64A Expired GB1074082A (en) | 1963-07-22 | 1964-07-09 | Dibenzocycloheptene compounds |
| GB35402/66A Expired GB1074083A (en) | 1963-07-22 | 1964-07-09 | Dibenzocycloheptene compounds |
| GB35404/66A Expired GB1074085A (en) | 1963-07-22 | 1964-07-09 | Dibenzocycloheptene compounds |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US3390179A (en) |
| BE (1) | BE650800A (en) |
| BR (1) | BR6460953D0 (en) |
| CH (1) | CH494731A (en) |
| DE (1) | DE1468339A1 (en) |
| DK (3) | DK127723B (en) |
| FR (2) | FR1572128A (en) |
| GB (4) | GB1074082A (en) |
| IL (2) | IL21665A (en) |
| NL (1) | NL6408390A (en) |
| SE (3) | SE332820B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3905981A (en) * | 1973-10-12 | 1975-09-16 | Research Corp | N-dealkylation of tertiary amines |
| US4089864A (en) * | 1974-03-25 | 1978-05-16 | Merck & Co., Inc. | 4-(10,11-Dihydro-cis and trans-10,11-dihydroxy-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidines |
| US3894032A (en) * | 1974-04-10 | 1975-07-08 | Merck & Co Inc | 10,11-Furo derivatives of cyproheptadine |
| US4044143A (en) * | 1975-01-30 | 1977-08-23 | Merck & Co., Inc. | 10,11-Bis-(hydroxyalkyl) derivatives of cyproheptadine |
| DE4232173A1 (en) * | 1992-09-25 | 1994-03-31 | Bayer Ag | 5-oxo-dibenzo (a, d) cyclohepta-1,4-diene |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3234279A (en) * | 1962-09-14 | 1966-02-08 | Merck & Co Inc | 5-(gamma-amino-propyl- and propylidene-) 5h-dibenzo[a, d]-10-hydroxy-10, 11-dihydrocycloheptenes and amine borane salts thereof |
-
1963
- 1963-07-22 US US296463A patent/US3390179A/en not_active Expired - Lifetime
-
1964
- 1964-07-02 SE SE09743/67A patent/SE332820B/xx unknown
- 1964-07-07 IL IL21665A patent/IL21665A/en unknown
- 1964-07-07 IL IL29677A patent/IL29677A/en unknown
- 1964-07-09 GB GB28412/64A patent/GB1074082A/en not_active Expired
- 1964-07-09 GB GB35402/66A patent/GB1074083A/en not_active Expired
- 1964-07-09 GB GB35404/66A patent/GB1074085A/en not_active Expired
- 1964-07-09 GB GB35403/66A patent/GB1074084A/en not_active Expired
- 1964-07-17 BR BR160953/64A patent/BR6460953D0/en unknown
- 1964-07-20 BE BE650800D patent/BE650800A/xx unknown
- 1964-07-21 FR FR1572128D patent/FR1572128A/fr not_active Expired
- 1964-07-21 SE SE8875/64A patent/SE320963B/xx unknown
- 1964-07-21 CH CH953364A patent/CH494731A/en not_active IP Right Cessation
- 1964-07-21 DK DK362064AA patent/DK127723B/en unknown
- 1964-07-21 SE SE09742/67A patent/SE332819B/xx unknown
- 1964-07-21 DE DE19641468339 patent/DE1468339A1/en active Pending
- 1964-07-22 NL NL6408390A patent/NL6408390A/xx unknown
- 1964-10-20 FR FR992062A patent/FR3905M/fr not_active Expired
-
1965
- 1965-07-09 DK DK351265AA patent/DK121856B/en unknown
- 1965-07-09 DK DK351165AA patent/DK121757B/en unknown
-
1970
- 1970-06-22 US US48478A patent/US3660389A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK127723B (en) | 1973-12-24 |
| FR3905M (en) | 1966-02-07 |
| IL29677A (en) | 1969-01-29 |
| GB1074083A (en) | 1967-06-28 |
| SE320963B (en) | 1970-02-23 |
| CH494731A (en) | 1970-08-15 |
| DK121856B (en) | 1971-12-13 |
| BR6460953D0 (en) | 1973-08-02 |
| GB1074085A (en) | 1967-06-28 |
| FR1572128A (en) | 1969-06-27 |
| US3660389A (en) | 1972-05-02 |
| SE332820B (en) | 1971-02-22 |
| US3390179A (en) | 1968-06-25 |
| BE650800A (en) | 1965-01-20 |
| SE332819B (en) | 1971-02-22 |
| DE1468339A1 (en) | 1968-12-19 |
| IL21665A (en) | 1969-01-29 |
| GB1074082A (en) | 1967-06-28 |
| NL6408390A (en) | 1965-01-25 |
| DK121757B (en) | 1971-11-29 |
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