GB1022869A - New derivatives of glycyrrhetinic acid - Google Patents

New derivatives of glycyrrhetinic acid

Info

Publication number
GB1022869A
GB1022869A GB44938/63A GB4493863A GB1022869A GB 1022869 A GB1022869 A GB 1022869A GB 44938/63 A GB44938/63 A GB 44938/63A GB 4493863 A GB4493863 A GB 4493863A GB 1022869 A GB1022869 A GB 1022869A
Authority
GB
United Kingdom
Prior art keywords
carboxylic acid
group
glycyrrhetinic acid
glycyrretinic
alkyl radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB44938/63A
Inventor
Eustace Ebenezer Turner
John Cameron Turner
William Alan Mcfarlane Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biorex Laboratories Ltd
Original Assignee
Biorex Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biorex Laboratories Ltd filed Critical Biorex Laboratories Ltd
Publication of GB1022869A publication Critical patent/GB1022869A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:1022869/C2/1> where R is an alkyl radical and R1 is an alkyl radical which may contain one or more free carboxylic acid groups and the salts of those compounds in which R1 contains one or more free carboxylic acid groups; and the preparation thereof by esterifying the carboxylic acid group of the glycyrretinic acid using a diazoalkane and then acylating the hydroxyl group of the resulting glycyrretinic acid ester using the required anhydrous mono- or polycarboxylic acids or the anhydrides or acid halides thereof and, when desired, neutralizing with an alkali to produce a salt. In the case where R1 is an unsubstituted alkyl group the acylation may precede the esterification.
GB44938/63A 1964-05-22 1963-11-14 New derivatives of glycyrrhetinic acid Expired GB1022869A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2114764 1964-05-22

Publications (1)

Publication Number Publication Date
GB1022869A true GB1022869A (en) 1966-03-16

Family

ID=10157986

Family Applications (1)

Application Number Title Priority Date Filing Date
GB44938/63A Expired GB1022869A (en) 1964-05-22 1963-11-14 New derivatives of glycyrrhetinic acid

Country Status (1)

Country Link
GB (1) GB1022869A (en)

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