GB1015014A - Novel steroid compounds and processes for their preparation - Google Patents
Novel steroid compounds and processes for their preparationInfo
- Publication number
- GB1015014A GB1015014A GB3941764A GB3941764A GB1015014A GB 1015014 A GB1015014 A GB 1015014A GB 3941764 A GB3941764 A GB 3941764A GB 3941764 A GB3941764 A GB 3941764A GB 1015014 A GB1015014 A GB 1015014A
- Authority
- GB
- United Kingdom
- Prior art keywords
- gona
- propyl
- processes
- preparation
- cyclic ketal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Abstract
The invention comprises the 3-cyclic ketals of 13b - n - propyl - gona - 4,9 - dien - 3 - one having the general formula <FORM:1015014/C2/1> in which R and R1, which may be the same or different, each represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms and nis either 0 or 1 and R2 is the oxygen atom -O of a keto group, or hydrogen together with either an acyloxy group in the b orientation derived from an organic carboxylic acid having from 1-18 carbon atoms, or a b -hydroxy group and processes for the preparation thereof in which a 17b -acyloxy-13b -n-propyl-gona-4,9-dien-3-one is reacted with a ketalizing agent to form the corresponding 3-cyclic ketal, subjecting said cyclic ketal to saponification to obtain a 3-cyclic ketal of 17b -hydroxy-13b -n-propyl-gona-4,9-diene-3-one and oxidizing this compound to obtain a 3-cyclic ketal of 13b -n-propyl-gona-4,9-diene-3,17-dione.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR867160A FR1369955A (en) | 1961-07-06 | 1961-07-06 | Gonadiene derivative and method of preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1015014A true GB1015014A (en) | 1965-12-31 |
Family
ID=8758780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3941764A Expired GB1015014A (en) | 1961-07-06 | 1962-07-06 | Novel steroid compounds and processes for their preparation |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR1369955A (en) |
GB (1) | GB1015014A (en) |
-
1961
- 1961-07-06 FR FR867160A patent/FR1369955A/en not_active Expired
-
1962
- 1962-07-06 GB GB3941764A patent/GB1015014A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR1369955A (en) | 1964-08-21 |
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