GB0907070D0 - methods for the treatment of otic disorders comprising glutamate agonists and antagonists - Google Patents
methods for the treatment of otic disorders comprising glutamate agonists and antagonistsInfo
- Publication number
- GB0907070D0 GB0907070D0 GB0907070A GB0907070A GB0907070D0 GB 0907070 D0 GB0907070 D0 GB 0907070D0 GB 0907070 A GB0907070 A GB 0907070A GB 0907070 A GB0907070 A GB 0907070A GB 0907070 D0 GB0907070 D0 GB 0907070D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- antagonists
- treatment
- methods
- otic disorders
- glutamate agonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (22)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2009/048954 WO2010011466A2 (en) | 2008-06-27 | 2009-06-26 | Controlled-release cns modulating compositions and methods for the treatment of otic disorders |
US12/494,156 US20090325938A1 (en) | 2008-06-27 | 2009-06-29 | Controlled-release cns modulating compositions and methods for the treatment of otic disorders |
US12/504,553 US8496957B2 (en) | 2008-07-21 | 2009-07-16 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
PCT/US2009/051078 WO2010062413A1 (en) | 2008-07-21 | 2009-07-17 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
EP09835529.0A EP2299976A4 (en) | 2008-12-22 | 2009-12-10 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
CN201610730867.1A CN106344495A (en) | 2008-12-22 | 2009-12-10 | Controlled release corticosteroid compositions and methods for the treatment of otic disorders |
CA2732686A CA2732686C (en) | 2008-12-22 | 2009-12-10 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
AU2009330458A AU2009330458B2 (en) | 2008-12-22 | 2009-12-10 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
CN2009801305625A CN102112111A (en) | 2008-12-22 | 2009-12-10 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
JP2011542272A JP6013736B2 (en) | 2008-12-22 | 2009-12-10 | Controlled release of an ear sensory cell modulator composition for the treatment of otic disorders and methods thereof |
PCT/US2009/067552 WO2010074992A2 (en) | 2008-12-22 | 2009-12-10 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
US12/767,461 US8575122B2 (en) | 2008-07-21 | 2010-04-26 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
US13/425,217 US8852626B2 (en) | 2008-06-27 | 2012-03-20 | Controlled-release CNS modulating compositions and methods for the treatment of otic disorders |
US13/928,157 US9066855B2 (en) | 2008-07-21 | 2013-06-26 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
JP2015095099A JP6207093B2 (en) | 2008-12-22 | 2015-05-07 | Controlled release of an ear sensory cell modulator composition for the treatment of otic disorders and methods thereof |
US14/713,944 US9808460B2 (en) | 2008-07-21 | 2015-05-15 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
US14/795,825 US20150313839A1 (en) | 2008-07-21 | 2015-07-09 | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
US15/091,148 US20170000728A1 (en) | 2008-06-27 | 2016-04-05 | Controlled-Release CNS Modulating Compositions and Methods for the Treatment of Otic Disorders |
JP2017087624A JP2017160232A (en) | 2008-12-22 | 2017-04-26 | Controlled release of auris sensory cell modulator compositions for treatment of otic disorders and methods therefor |
JP2018083451A JP2018138585A (en) | 2008-12-22 | 2018-04-24 | Controlled release of auris sensory cell modulator compositions for the treatment of otic disorders and methods therefor |
US16/447,776 US10918594B2 (en) | 2008-06-27 | 2019-06-20 | Controlled-release CNS modulating compositions and methods for the treatment of otic disorders |
US17/146,909 US20210220263A1 (en) | 2008-06-27 | 2021-01-12 | Controlled-release cns modulating compositions and methods for the treatment of otic disorders |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8383008P | 2008-07-25 | 2008-07-25 | |
US8609408P | 2008-08-04 | 2008-08-04 | |
US16023309P | 2009-03-13 | 2009-03-13 | |
US16481209P | 2009-03-30 | 2009-03-30 |
Publications (3)
Publication Number | Publication Date |
---|---|
GB0907070D0 true GB0907070D0 (en) | 2009-06-03 |
GB2461962A GB2461962A (en) | 2010-01-27 |
GB2461962B GB2461962B (en) | 2011-02-16 |
Family
ID=40774914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB0907070A Expired - Fee Related GB2461962B (en) | 2008-06-27 | 2009-04-24 | Slow release NMDA receptor antagonist for otic disorders |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB2461962B (en) |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060063802A1 (en) * | 2004-03-29 | 2006-03-23 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
JP2008531726A (en) * | 2005-03-04 | 2008-08-14 | ニューロシステック コーポレイション | Improved gacyclidine formulation |
RS53591B1 (en) * | 2005-09-28 | 2015-02-27 | Auris Medical Ag | Pharmaceutical compositions for the treatment of inner ear disorders |
CN101134780A (en) * | 2007-07-09 | 2008-03-05 | 南京医科大学 | Polypeptide analogue for blocking NR2B signal path and preparation method and medical usage thereof |
US20090239836A1 (en) * | 2008-03-24 | 2009-09-24 | Mary Lee Ciolkowski | Multifunctional Ophthalmic Compositions |
GB2461186B (en) * | 2008-04-21 | 2010-09-01 | Otonomy Inc | Controlled release corticosteroid compositions and methods for the treatment of otic disorders |
MX2010011545A (en) * | 2008-04-21 | 2011-04-11 | Otonomy Inc | Auris formulations for treating otic diseases and conditions. |
-
2009
- 2009-04-24 GB GB0907070A patent/GB2461962B/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
GB2461962B (en) | 2011-02-16 |
GB2461962A (en) | 2010-01-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20200424 |