GB0808029D0 - Antifungal target - Google Patents
Antifungal targetInfo
- Publication number
- GB0808029D0 GB0808029D0 GBGB0808029.3A GB0808029A GB0808029D0 GB 0808029 D0 GB0808029 D0 GB 0808029D0 GB 0808029 A GB0808029 A GB 0808029A GB 0808029 D0 GB0808029 D0 GB 0808029D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- antifungal target
- antifungal
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/05—Oxidoreductases acting on the CH-CH group of donors (1.3) with a quinone or related compound as acceptor (1.3.5)
- C12Y103/05002—Dihydroorotate dehydrogenase (1.3.5.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90206—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0808029.3A GB0808029D0 (en) | 2008-05-01 | 2008-05-01 | Antifungal target |
NZ588703A NZ588703A (en) | 2008-05-01 | 2009-05-01 | Dihydroorotate dehydrogenase as antifungal drug target and quinazolinone-based inhibitors thereof |
AU2009241646A AU2009241646B2 (en) | 2008-05-01 | 2009-05-01 | Dihydroorotate dehydrogenase as antifungal drug target and quinazolinone-based inhibitors thereof |
PCT/GB2009/001114 WO2009133379A2 (en) | 2008-05-01 | 2009-05-01 | Antifungal target |
CA2721959A CA2721959A1 (en) | 2008-05-01 | 2009-05-01 | A method of identifying an antifungal target to dihydroorotate dehydrogenase |
US12/990,478 US9034887B2 (en) | 2008-05-01 | 2009-05-01 | Dihydroorotate dehydrogenase as antifungal drug target and quinazolinone-based inhibitors thereof |
EP09738409.3A EP2283151B1 (en) | 2008-05-01 | 2009-05-01 | Dihydroorotate dehydrogenase as antifungal drug target |
JP2011506773A JP5901967B2 (en) | 2008-05-01 | 2009-05-01 | Dihydroorotate dehydrogenase and its quinazolinone inhibitors as targets for antifungal agents |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0808029.3A GB0808029D0 (en) | 2008-05-01 | 2008-05-01 | Antifungal target |
Publications (1)
Publication Number | Publication Date |
---|---|
GB0808029D0 true GB0808029D0 (en) | 2008-06-11 |
Family
ID=39537191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB0808029.3A Ceased GB0808029D0 (en) | 2008-05-01 | 2008-05-01 | Antifungal target |
Country Status (8)
Country | Link |
---|---|
US (1) | US9034887B2 (en) |
EP (1) | EP2283151B1 (en) |
JP (1) | JP5901967B2 (en) |
AU (1) | AU2009241646B2 (en) |
CA (1) | CA2721959A1 (en) |
GB (1) | GB0808029D0 (en) |
NZ (1) | NZ588703A (en) |
WO (1) | WO2009133379A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8686048B2 (en) | 2010-05-06 | 2014-04-01 | Rhizen Pharmaceuticals Sa | Immunomodulator and anti-inflammatory compounds |
US20140031383A1 (en) | 2011-02-08 | 2014-01-30 | Dana-Farber Cancer Institute, Inc. | Methods for treatment of melanoma |
SG11201702516UA (en) | 2014-10-23 | 2017-04-27 | Sanofi Sa | Novel selection marker for cell transfection and protein production |
ES2544519B1 (en) * | 2015-05-22 | 2016-03-04 | Consejo Superior De Investigaciones Científicas (Csic) | S-substituted quinazolines and their therapeutic applications for the treatment of diseases mediated by PDE7 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5976848A (en) * | 1990-08-03 | 1999-11-02 | Dow Agrosciences Llc | Method of identifying potential fungicides using dihydroorotate dehydrogenase inhibition assay |
US6951847B2 (en) * | 2000-09-29 | 2005-10-04 | Regents Of The University Of Minnesota | Methods of treating fungal infections using lupeol |
US20030180953A1 (en) * | 2000-12-29 | 2003-09-25 | Elitra Pharmaceuticals, Inc. | Gene disruption methodologies for drug target discovery |
WO2002086090A2 (en) * | 2001-04-23 | 2002-10-31 | Elitra Pharmaceuticals, Inc. | Identification of essential genes of aspegillus fumigatus and methods of use |
-
2008
- 2008-05-01 GB GBGB0808029.3A patent/GB0808029D0/en not_active Ceased
-
2009
- 2009-05-01 EP EP09738409.3A patent/EP2283151B1/en not_active Not-in-force
- 2009-05-01 JP JP2011506773A patent/JP5901967B2/en not_active Expired - Fee Related
- 2009-05-01 CA CA2721959A patent/CA2721959A1/en not_active Abandoned
- 2009-05-01 AU AU2009241646A patent/AU2009241646B2/en not_active Ceased
- 2009-05-01 NZ NZ588703A patent/NZ588703A/en not_active IP Right Cessation
- 2009-05-01 US US12/990,478 patent/US9034887B2/en not_active Expired - Fee Related
- 2009-05-01 WO PCT/GB2009/001114 patent/WO2009133379A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
AU2009241646B2 (en) | 2015-02-05 |
WO2009133379A8 (en) | 2010-02-25 |
NZ588703A (en) | 2012-10-26 |
WO2009133379A3 (en) | 2009-12-23 |
EP2283151B1 (en) | 2017-03-08 |
AU2009241646A1 (en) | 2009-11-05 |
US20110160231A1 (en) | 2011-06-30 |
US9034887B2 (en) | 2015-05-19 |
JP2011520431A (en) | 2011-07-21 |
WO2009133379A2 (en) | 2009-11-05 |
CA2721959A1 (en) | 2009-11-05 |
EP2283151A2 (en) | 2011-02-16 |
JP5901967B2 (en) | 2016-04-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |