GB0509224D0 - Inhibitors of intracellular enzymatic activity - Google Patents

Inhibitors of intracellular enzymatic activity

Info

Publication number
GB0509224D0
GB0509224D0 GBGB0509224.2A GB0509224A GB0509224D0 GB 0509224 D0 GB0509224 D0 GB 0509224D0 GB 0509224 A GB0509224 A GB 0509224A GB 0509224 D0 GB0509224 D0 GB 0509224D0
Authority
GB
United Kingdom
Prior art keywords
inhibitors
enzymatic activity
intracellular enzymatic
intracellular
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0509224.2A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chroma Therapeutics Ltd
Original Assignee
Chroma Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chroma Therapeutics Ltd filed Critical Chroma Therapeutics Ltd
Priority to GBGB0509224.2A priority Critical patent/GB0509224D0/en
Publication of GB0509224D0 publication Critical patent/GB0509224D0/en
Priority to PCT/GB2006/001644 priority patent/WO2006117570A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
GBGB0509224.2A 2005-05-05 2005-05-05 Inhibitors of intracellular enzymatic activity Ceased GB0509224D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB0509224.2A GB0509224D0 (en) 2005-05-05 2005-05-05 Inhibitors of intracellular enzymatic activity
PCT/GB2006/001644 WO2006117570A1 (en) 2005-05-05 2006-05-04 Quinoline derivatives as kinase enzyme inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0509224.2A GB0509224D0 (en) 2005-05-05 2005-05-05 Inhibitors of intracellular enzymatic activity

Publications (1)

Publication Number Publication Date
GB0509224D0 true GB0509224D0 (en) 2005-06-15

Family

ID=34685156

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0509224.2A Ceased GB0509224D0 (en) 2005-05-05 2005-05-05 Inhibitors of intracellular enzymatic activity

Country Status (2)

Country Link
GB (1) GB0509224D0 (en)
WO (1) WO2006117570A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7432377B2 (en) 2004-01-16 2008-10-07 Wyeth Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof
CA2581516C (en) 2004-10-12 2013-06-11 Astrazeneca Ab Quinazoline derivatives
BRPI0610368A8 (en) * 2005-05-05 2015-09-08 Glaxosmithkline Ip Dev Ltd ENZYME AND RECEPTOR MODULATION
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
UY30183A1 (en) 2006-03-02 2007-10-31 Astrazeneca Ab QUINOLINE DERIVATIVES
MX2009003793A (en) 2006-10-09 2009-12-14 Takeda Pharmaceutical Kinase inhibitors.
PE20090717A1 (en) 2007-05-18 2009-07-18 Smithkline Beecham Corp QUINOLINE DERIVATIVES AS PI3 KINASE INHIBITORS
GB0903480D0 (en) 2009-02-27 2009-04-08 Chroma Therapeutics Ltd Enzyme Inhibitors
IN2012DN02534A (en) 2009-09-16 2015-08-28 Avila Therapeutics Inc
BR112012015721A2 (en) 2009-12-30 2017-09-26 Avila Therapeutics Inc covalent ligand-driven protein modification
US9428460B2 (en) 2012-06-26 2016-08-30 Bayer Pharma Aktiengesellschaft N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products
JP6669499B2 (en) 2013-02-15 2020-03-18 カラ ファーマシューティカルズ インコーポレイテッド Therapeutic compounds
ES2831625T3 (en) 2013-02-20 2021-06-09 Kala Pharmaceuticals Inc Therapeutic compounds and their uses
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
CN106061261B (en) 2013-11-01 2018-04-24 卡拉制药公司 Crystal form of therapeutic compounds and application thereof
SG11201700776XA (en) 2014-08-01 2017-02-27 Nuevolution As Compounds active towards bromodomains
AU2017324716B2 (en) 2016-09-08 2020-08-13 KALA BIO, Inc. Crystalline forms of therapeutic compounds and uses thereof
KR20190051010A (en) 2016-09-08 2019-05-14 칼라 파마슈티컬스, 인크. Crystalline Forms of Therapeutic Compounds and Their Uses
AU2017324713B2 (en) 2016-09-08 2020-08-13 KALA BIO, Inc. Crystalline forms of therapeutic compounds and uses thereof
CA3093189A1 (en) 2018-03-07 2019-09-12 Bayer Aktiengesellschaft Identification and use of erk5 inhibitors
WO2020234103A1 (en) 2019-05-21 2020-11-26 Bayer Aktiengesellschaft Identification and use of kras inhibitors
CN112778217B (en) * 2019-11-08 2024-01-26 沈阳化工研究院有限公司 Quinazoline compound and application thereof
WO2021152113A1 (en) 2020-01-31 2021-08-05 Bayer Aktiengesellschaft Substituted 2,3-benzodiazepines derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021594A1 (en) * 1999-09-21 2001-03-29 Astrazeneca Ab Quinazoline compounds and pharmaceutical compositions containing them
AU2001228638A1 (en) * 2000-01-28 2001-08-07 Astrazeneca Ab Chemical compounds
AUPQ841300A0 (en) * 2000-06-27 2000-07-20 Fujisawa Pharmaceutical Co., Ltd. New aminoalcohol derivatives
TW200536851A (en) * 2004-01-23 2005-11-16 Amgen Inc Compounds and methods of use
WO2005097137A2 (en) * 2004-03-31 2005-10-20 The Scripps Research Institute Advanced quinazoline based protein kinase inhibitors

Also Published As

Publication number Publication date
WO2006117570A1 (en) 2006-11-09

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)