FR3079524B1 - BIOCOMPATIBLE HYDROGEL MICROWELL PLATES - Google Patents

BIOCOMPATIBLE HYDROGEL MICROWELL PLATES Download PDF

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Publication number
FR3079524B1
FR3079524B1 FR1870349A FR1870349A FR3079524B1 FR 3079524 B1 FR3079524 B1 FR 3079524B1 FR 1870349 A FR1870349 A FR 1870349A FR 1870349 A FR1870349 A FR 1870349A FR 3079524 B1 FR3079524 B1 FR 3079524B1
Authority
FR
France
Prior art keywords
biocompatible hydrogel
microwell plates
cell aggregates
hydrogel microwell
growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1870349A
Other languages
French (fr)
Other versions
FR3079524A1 (en
Inventor
Charlotte Riviere
Audrey Prunet
Layla Fuoco
Helene Ayari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite Claude Bernard Lyon 1 UCBL
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite Claude Bernard Lyon 1 UCBL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite Claude Bernard Lyon 1 UCBL filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR1870349A priority Critical patent/FR3079524B1/en
Publication of FR3079524A1 publication Critical patent/FR3079524A1/en
Application granted granted Critical
Publication of FR3079524B1 publication Critical patent/FR3079524B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/22—Transparent or translucent parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates

Abstract

L'invention concerne une plaque de micropuits en hydrogel biocompatible adaptés à la croissance d'agrégats cellulaires, son procédé de préparation et son utilisation pour la croissance d'agrégats cellulaires dans les puits, en particulier pour observer la réponse des agrégats cellulaires cultivés en réaction à des stimuli, comme par exemple leur exposition à des substances toxiques ou à des candidats médicaments.The invention relates to a plate of biocompatible hydrogel microwells suitable for the growth of cell aggregates, its method of preparation and its use for the growth of cell aggregates in wells, in particular for observing the response of cell aggregates cultured in reaction. to stimuli, such as for example their exposure to toxic substances or to drug candidates.

FR1870349A 2018-03-27 2018-03-27 BIOCOMPATIBLE HYDROGEL MICROWELL PLATES Expired - Fee Related FR3079524B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR1870349A FR3079524B1 (en) 2018-03-27 2018-03-27 BIOCOMPATIBLE HYDROGEL MICROWELL PLATES

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1870349 2018-03-27
FR1870349A FR3079524B1 (en) 2018-03-27 2018-03-27 BIOCOMPATIBLE HYDROGEL MICROWELL PLATES

Publications (2)

Publication Number Publication Date
FR3079524A1 FR3079524A1 (en) 2019-10-04
FR3079524B1 true FR3079524B1 (en) 2020-12-18

Family

ID=62816855

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1870349A Expired - Fee Related FR3079524B1 (en) 2018-03-27 2018-03-27 BIOCOMPATIBLE HYDROGEL MICROWELL PLATES

Country Status (1)

Country Link
FR (1) FR3079524B1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3107901A1 (en) 2020-03-09 2021-09-10 Commissariat A L'energie Atomique Et Aux Energies Alternatives Microfluidic perfusion method of a spheroid and device adapted to implement said method
IT202100025460A1 (en) * 2021-10-07 2023-04-07 Univ Degli Studi Di Roma “Tor Vergata” LAB-ON-CHIP DEVICE TO STUDY CELLULAR MIGRATION IN THREE-DIMENSIONAL SYSTEMS AND RELATED METHOD OF USE
WO2023191681A1 (en) * 2022-03-28 2023-10-05 Gradientech Ab Adherence enhancing coating for plastic surfaces

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007087402A2 (en) * 2006-01-24 2007-08-02 Brown University Cell aggregation and encapsulation device and method
US10655107B2 (en) * 2011-09-20 2020-05-19 Corning Incorporated Adherent cell culture method
DK3237597T3 (en) * 2014-12-22 2021-03-15 Ecole Polytechnique Fed Lausanne Epfl FACILITIES FOR HIGH FLOW AGGREGATION AND MANIPULATION OF MAMMAL CELLS

Also Published As

Publication number Publication date
FR3079524A1 (en) 2019-10-04

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