FR3017294B1 - LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY - Google Patents
LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY Download PDFInfo
- Publication number
- FR3017294B1 FR3017294B1 FR1450964A FR1450964A FR3017294B1 FR 3017294 B1 FR3017294 B1 FR 3017294B1 FR 1450964 A FR1450964 A FR 1450964A FR 1450964 A FR1450964 A FR 1450964A FR 3017294 B1 FR3017294 B1 FR 3017294B1
- Authority
- FR
- France
- Prior art keywords
- antibiotic
- nanocapsules
- lipid
- therapy
- lipid nanoparticles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000002632 lipids Chemical class 0.000 title abstract 3
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 239000002088 nanocapsule Substances 0.000 abstract 3
- 239000007788 liquid Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000004779 membrane envelope Anatomy 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
La présente invention se rapporte à des nanocapsules lipidiques comprenant un cœur lipidique liquide ou semi-liquide à température ambiante dans lequel est incorporé au moins un antibiotique, le cœur étant enveloppé d'une enveloppe lipidique solide à température ambiante, et à une composition pharmaceutique comprenant de telles nanocapsules pour traiter ou prévenir une infection bactérienne touchant une articulation, un os ou la peau. La présente invention porte également sur des dispositifs médicaux comprenant de telles nanocapsules ou composition pharmaceutiques.The present invention relates to lipid nanocapsules comprising a liquid or semi-liquid lipid core at ambient temperature in which at least one antibiotic is incorporated, the core being enveloped in a lipid envelope which is solid at ambient temperature, and to a pharmaceutical composition comprising such nanocapsules for treating or preventing bacterial infection affecting a joint, bone or skin. The present invention also relates to medical devices comprising such nanocapsules or pharmaceutical compositions.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1450964A FR3017294B1 (en) | 2014-02-07 | 2014-02-07 | LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY |
PCT/IB2015/050913 WO2015118496A1 (en) | 2014-02-07 | 2015-02-06 | Lipid nanocapsules containing an antibiotic and therapeutic uses thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1450964A FR3017294B1 (en) | 2014-02-07 | 2014-02-07 | LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3017294A1 FR3017294A1 (en) | 2015-08-14 |
FR3017294B1 true FR3017294B1 (en) | 2021-10-01 |
Family
ID=50624776
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1450964A Active FR3017294B1 (en) | 2014-02-07 | 2014-02-07 | LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR3017294B1 (en) |
WO (1) | WO2015118496A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3679928A1 (en) * | 2019-01-08 | 2020-07-15 | Atlangram | Gel type pharmaceutical composition for treating/preventing an infection |
KR20220020963A (en) | 2019-06-14 | 2022-02-21 | 데비오팜 인터네셔날 에스 에이 | Medicines and uses thereof for treating biofilm-associated bacterial infections |
CN112263395B (en) * | 2020-09-18 | 2021-12-14 | 浙江珍琦护理用品有限公司 | Panty-shape diapers convenient to adjust size |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2805761B1 (en) | 2000-03-02 | 2002-08-30 | Mainelab | LIPID NANOCAPSULES, METHOD OF PREPARATION AND USE AS A MEDICAMENT |
FR2840532B1 (en) * | 2002-06-11 | 2005-05-06 | Ethypharm Sa | FURENT LIPID NANOCAPSULES, PROCESS FOR THEIR PREPARATION AND USE AS VECTOR OF ACTIVE (S) PRINCIPLES |
FR2916973B1 (en) | 2007-06-11 | 2010-02-26 | Univ Angers | NANOCAPSULES WITH LIPIDIC HEAD CHARGED WITH HYDROSOLUBLE (S) OR HYDRODISPERSIBLE ACTIVE (S) |
FR2916974B1 (en) | 2007-06-11 | 2010-11-26 | Univ Angers | PROCESS FOR THE PREPARATION OF LIPID NANOPARTICLES |
FR2939699B1 (en) | 2008-12-12 | 2011-05-06 | Univ Angers | PROCESS FOR THE PREPARATION OF LIPID NANOPARTICLES |
US9492398B2 (en) * | 2011-02-25 | 2016-11-15 | Eydo Pharma | Nanocapsulation of essential oils for preventing or curing infectious diseases alone or with an antibiotic |
-
2014
- 2014-02-07 FR FR1450964A patent/FR3017294B1/en active Active
-
2015
- 2015-02-06 WO PCT/IB2015/050913 patent/WO2015118496A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2015118496A1 (en) | 2015-08-13 |
FR3017294A1 (en) | 2015-08-14 |
WO2015118496A4 (en) | 2015-10-08 |
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