FR2984744B1 - Nouvelle association entre le n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl) benzofuran-2-ylcarbonylamino] ethoxy} benzamide et le cisplatine dans le carcinome du nasopharynx - Google Patents

Nouvelle association entre le n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl) benzofuran-2-ylcarbonylamino] ethoxy} benzamide et le cisplatine dans le carcinome du nasopharynx

Info

Publication number
FR2984744B1
FR2984744B1 FR1104067A FR1104067A FR2984744B1 FR 2984744 B1 FR2984744 B1 FR 2984744B1 FR 1104067 A FR1104067 A FR 1104067A FR 1104067 A FR1104067 A FR 1104067A FR 2984744 B1 FR2984744 B1 FR 2984744B1
Authority
FR
France
Prior art keywords
ylcarbonylamino
dimethylaminomethyl
benzofuran
benzamide
cisplatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1104067A
Other languages
English (en)
Other versions
FR2984744A1 (fr
Inventor
Ioana Kloos
Bescond Anne Jacquet
Berthier Laurence Kraus
Stephane Depil
Benjamin Verillaud
Pierre Busson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacyclics LLC
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Priority to FR1104067A priority Critical patent/FR2984744B1/fr
Priority to UY0001034533A priority patent/UY34533A/es
Priority to ARP120104910A priority patent/AR089600A1/es
Priority to PCT/FR2012/000550 priority patent/WO2013093248A1/fr
Priority to TW101149177A priority patent/TW201328691A/zh
Publication of FR2984744A1 publication Critical patent/FR2984744A1/fr
Application granted granted Critical
Publication of FR2984744B1 publication Critical patent/FR2984744B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR1104067A 2011-12-23 2011-12-23 Nouvelle association entre le n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl) benzofuran-2-ylcarbonylamino] ethoxy} benzamide et le cisplatine dans le carcinome du nasopharynx Expired - Fee Related FR2984744B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR1104067A FR2984744B1 (fr) 2011-12-23 2011-12-23 Nouvelle association entre le n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl) benzofuran-2-ylcarbonylamino] ethoxy} benzamide et le cisplatine dans le carcinome du nasopharynx
UY0001034533A UY34533A (es) 2011-12-23 2012-12-19 Nueva asociación entre la n-hidroxi-4-{2-[3-(n,n- dimetilaminometil) benzofuran-2- ilcarbonilamino ]etoxi} benzamida y el cisplatino en el carcinoma de nasofaringe
ARP120104910A AR089600A1 (es) 2011-12-23 2012-12-21 Asociacion entre la n-hidroxi-4-{2-[3-(n,n-dimetilaminometil)benzofuran-2-ilcarbonilamino]etoxi}benzamida y el cisplatino en el carcinoma de nasofaringe
PCT/FR2012/000550 WO2013093248A1 (fr) 2011-12-23 2012-12-21 Nouvelles associations a base de n- hydroxy - 4 - { 2 - [3 - (n, n- dimethylaminomethyl) benzofuran- 2 -ylcarb onylamino] ethoxy} benzamide dans le carcinome du nasopharynx
TW101149177A TW201328691A (zh) 2011-12-23 2012-12-21 用於鼻咽癌之ｎ－羥基－４－｛２－［３－（ｎ，ｎ－二甲基胺基甲基）苯并呋喃－２－基羰基胺基］乙氧基｝苯甲醯胺及順鉑之新結合

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1104067A FR2984744B1 (fr) 2011-12-23 2011-12-23 Nouvelle association entre le n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl) benzofuran-2-ylcarbonylamino] ethoxy} benzamide et le cisplatine dans le carcinome du nasopharynx

Publications (2)

Publication Number Publication Date
FR2984744A1 FR2984744A1 (fr) 2013-06-28
FR2984744B1 true FR2984744B1 (fr) 2014-02-07

Family

ID=45855869

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1104067A Expired - Fee Related FR2984744B1 (fr) 2011-12-23 2011-12-23 Nouvelle association entre le n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl) benzofuran-2-ylcarbonylamino] ethoxy} benzamide et le cisplatine dans le carcinome du nasopharynx

Country Status (5)

Country Link
AR (1) AR089600A1 (fr)
FR (1) FR2984744B1 (fr)
TW (1) TW201328691A (fr)
UY (1) UY34533A (fr)
WO (1) WO2013093248A1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004230889B2 (en) 2003-04-07 2008-03-13 Pharmacyclics Llc Hydroxamates as therapeutic agents
US8623853B2 (en) * 2008-07-23 2014-01-07 The Brigham And Women's Hospital, Inc. Treatment of cancers characterized by chromosomal rearrangement of the NUT gene

Also Published As

Publication number Publication date
UY34533A (es) 2013-06-28
WO2013093248A1 (fr) 2013-06-27
FR2984744A1 (fr) 2013-06-28
AR089600A1 (es) 2014-09-03
TW201328691A (zh) 2013-07-16

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Legal Events

Date Code Title Description
TP Transmission of property

Owner name: PHARMACYCLICS, INC., US

Effective date: 20150730

PLFP Fee payment

Year of fee payment: 5

ST Notification of lapse

Effective date: 20170831