FR2972371B1 - METHOD OF FORMING DROPS FROM A FIRST PHASE DISPERSED IN A SECOND PHASE SUBSTANTIALLY IMMISCIBLE WITH THE FIRST PHASE - Google Patents

METHOD OF FORMING DROPS FROM A FIRST PHASE DISPERSED IN A SECOND PHASE SUBSTANTIALLY IMMISCIBLE WITH THE FIRST PHASE

Info

Publication number
FR2972371B1
FR2972371B1 FR1151885A FR1151885A FR2972371B1 FR 2972371 B1 FR2972371 B1 FR 2972371B1 FR 1151885 A FR1151885 A FR 1151885A FR 1151885 A FR1151885 A FR 1151885A FR 2972371 B1 FR2972371 B1 FR 2972371B1
Authority
FR
France
Prior art keywords
phase
fluid
polymer precursor
coacervate
substantially immiscible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1151885A
Other languages
French (fr)
Other versions
FR2972371A1 (en
Inventor
Mathieu Goutayer
Jerome Bibette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Capsum SAS
Original Assignee
Capsum SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1151885A priority Critical patent/FR2972371B1/en
Application filed by Capsum SAS filed Critical Capsum SAS
Priority to BR112013022027A priority patent/BR112013022027A2/en
Priority to EP19171412.0A priority patent/EP3552695B1/en
Priority to PCT/EP2012/053917 priority patent/WO2012120043A2/en
Priority to US14/003,527 priority patent/US10300006B2/en
Priority to EP12707331.0A priority patent/EP2683475B1/en
Priority to CN201280012312.3A priority patent/CN103635252B/en
Publication of FR2972371A1 publication Critical patent/FR2972371A1/en
Application granted granted Critical
Publication of FR2972371B1 publication Critical patent/FR2972371B1/en
Priority to US16/384,848 priority patent/US11026879B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/10—Complex coacervation, i.e. interaction of oppositely charged particles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
    • A23D7/005—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
    • A23D7/0053—Compositions other than spreads
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
    • A23D7/02—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by the production or working-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/896—Polysiloxanes containing atoms other than silicon, carbon, oxygen and hydrogen, e.g. dimethicone copolyol phosphate
    • A61K8/898—Polysiloxanes containing atoms other than silicon, carbon, oxygen and hydrogen, e.g. dimethicone copolyol phosphate containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Colloid Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)

Abstract

Forming drops (12) of a first phase (14) dispersed in a second phase (16) substantially immiscible with the first phase, comprises providing a first fluid (36) comprising the first phase and a first polymer precursor of the coacervate content in the first phase; forming drops of the first fluid into a second fluid (40) for forming the second phase; supplying a second polymer precursor of the coacervate in the second fluid; and creating the coacervate layer by interaction between the first polymer precursor and the second polymer precursor. Forming drops (12) of a first phase (14) dispersed in a second phase (16) substantially immiscible with the first phase, where each droplet has a core (17) formed of the first phase and a shell (18) formed of a coacervate layer interposed between the first phase and the second phase, comprises providing a first fluid (36) comprising the first phase and a first polymer precursor of the coacervate content in the first phase; forming drops of the first fluid into a second fluid (40) for forming the second phase; supplying a second polymer precursor of the coacervate in the second fluid; and during the formation of each droplet, or once each drop formed, creating the coacervate layer by interaction between the first polymer precursor and the second polymer precursor at the interface between the first phase and the second phase. An independent claim is included for a dispersion of drops of the first phase in the second phase substantially immiscible with the first phase obtainable by the above process.
FR1151885A 2011-03-08 2011-03-08 METHOD OF FORMING DROPS FROM A FIRST PHASE DISPERSED IN A SECOND PHASE SUBSTANTIALLY IMMISCIBLE WITH THE FIRST PHASE Active FR2972371B1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR1151885A FR2972371B1 (en) 2011-03-08 2011-03-08 METHOD OF FORMING DROPS FROM A FIRST PHASE DISPERSED IN A SECOND PHASE SUBSTANTIALLY IMMISCIBLE WITH THE FIRST PHASE
EP19171412.0A EP3552695B1 (en) 2011-03-08 2012-03-07 Dispersion of drops from a first phase dispersed in a second phase substantially non-miscible with the first phase
PCT/EP2012/053917 WO2012120043A2 (en) 2011-03-08 2012-03-07 Method for forming drops of a first phase dispersed in a second phase substantially immiscible with the first phase
US14/003,527 US10300006B2 (en) 2011-03-08 2012-03-07 Method for forming drops of a first phase, dispersed in a second phase substantially immiscible with the first phase
BR112013022027A BR112013022027A2 (en) 2011-03-08 2012-03-07 process of forming first phase droplets dispersed in a second phase substantially immiscible with the first phase
EP12707331.0A EP2683475B1 (en) 2011-03-08 2012-03-07 Method for forming drops of a first phase dispersed in a second phase substantially immiscible with the first phase
CN201280012312.3A CN103635252B (en) 2011-03-08 2012-03-07 The method forming drop and the dispersion of the drop formed
US16/384,848 US11026879B2 (en) 2011-03-08 2019-04-15 Dispersion of drops of a first phase, dispersed in a second phase substantially immiscible with the first phase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1151885A FR2972371B1 (en) 2011-03-08 2011-03-08 METHOD OF FORMING DROPS FROM A FIRST PHASE DISPERSED IN A SECOND PHASE SUBSTANTIALLY IMMISCIBLE WITH THE FIRST PHASE

Publications (2)

Publication Number Publication Date
FR2972371A1 FR2972371A1 (en) 2012-09-14
FR2972371B1 true FR2972371B1 (en) 2013-03-15

Family

ID=44550699

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1151885A Active FR2972371B1 (en) 2011-03-08 2011-03-08 METHOD OF FORMING DROPS FROM A FIRST PHASE DISPERSED IN A SECOND PHASE SUBSTANTIALLY IMMISCIBLE WITH THE FIRST PHASE

Country Status (1)

Country Link
FR (1) FR2972371B1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3012050B1 (en) * 2013-10-17 2016-01-01 Capsum METHOD OF FORMING A DISPERSION COMPRISING DROPS, AND APPARATUS THEREFOR
FR3046944B1 (en) 2016-01-22 2022-04-01 Capsum DEVICE FOR PACKAGING AND DISTRIBUTING A PRODUCT WITHOUT AIR INTAKE, IN PARTICULAR IN MULTIPLE PHASES, PURGE RING AND ASSOCIATED METHOD
FR3052034B1 (en) 2016-06-01 2019-06-14 Capsum DEVICE FOR CONDITIONING AND DISPENSING A COMPOSITION, IN PARTICULAR COSMETIC, RESULTING FROM THE USE OF AT LEAST TWO COMPOSITIONS
FR3066388B1 (en) 2017-05-16 2020-05-15 L V M H Recherche COSMETIC COMPOSITION COMPRISING ROSE EXTRACTS
FR3068238B1 (en) 2017-06-30 2020-07-31 Capsum THREE-PHASE COMPOSITION
FR3083118B1 (en) 2018-07-02 2021-01-08 Lvmh Rech GELIFIED COMPOSITION WITH UV FILTERS
FR3121042B1 (en) 2021-03-29 2023-11-10 Laboratoires Lea New composition comprising a fatty phase dispersed in the form of droplets in a continuous liquid aqueous phase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD160393A3 (en) * 1980-11-14 1983-07-27 Horst Dautzenberg MICRO CAPSULES AND METHOD FOR THE PRODUCTION THEREOF
EP1524030A1 (en) * 2003-10-18 2005-04-20 Cognis Iberia S.L Process and device for making microcapsules
FR2939012B1 (en) * 2008-12-01 2015-03-27 Capsum PROCESS FOR MANUFACTURING A SERIES OF CAPSULES, AND ASSOCIATED SERIES OF CAPSULES
CN101612139B (en) * 2009-07-13 2011-08-31 四川大学 Thermal initiation spontaneous explosion type magnetically targeted micro-capsule and preparation method thereof

Also Published As

Publication number Publication date
FR2972371A1 (en) 2012-09-14

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