FR2955257B1 - METHOD OF MANUFACTURING CAPSULES WITH CONTROLLED FALL HEIGHT. - Google Patents

METHOD OF MANUFACTURING CAPSULES WITH CONTROLLED FALL HEIGHT.

Info

Publication number
FR2955257B1
FR2955257B1 FR1050262A FR1050262A FR2955257B1 FR 2955257 B1 FR2955257 B1 FR 2955257B1 FR 1050262 A FR1050262 A FR 1050262A FR 1050262 A FR1050262 A FR 1050262A FR 2955257 B1 FR2955257 B1 FR 2955257B1
Authority
FR
France
Prior art keywords
solution
drop
fall height
manufacturing capsules
controlled fall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1050262A
Other languages
French (fr)
Other versions
FR2955257A1 (en
Inventor
Nicolas Bremond
Carreras Enric Santanach
Jerome Bibette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Capsum SAS
Original Assignee
Capsum SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Capsum SAS filed Critical Capsum SAS
Priority to FR1050262A priority Critical patent/FR2955257B1/en
Priority to PCT/FR2011/050064 priority patent/WO2011086331A2/en
Publication of FR2955257A1 publication Critical patent/FR2955257A1/en
Application granted granted Critical
Publication of FR2955257B1 publication Critical patent/FR2955257B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

Ce procédé comprend le convoyage séparé dans une double enveloppe (32) d'une première solution liquide (36) et d'une deuxième solution liquide (40). Il comprend la formation à la sortie de la double enveloppe (32) d'une série de gouttes (78), chaque goutte (78) comprenant un noyau central (80) formé de première solution (36) et une pellicule périphérique (82) formée de deuxième solution (40). Le procédé comporte la chute de chaque goutte (78) dans un volume gazeux à la sortie de la double enveloppe (32) et l'immersion de chaque goutte (78) dans une solution gélifiante (70) pour former une enveloppe gélifiée. Le rapport de l'énergie cinétique de la goutte (78), au carré de son rayon, lorsqu'elle entre en contact avec la solution gélifiante (70) est supérieur à 1 J/m2.This method comprises the separate conveying in a jacket (32) of a first liquid solution (36) and a second liquid solution (40). It comprises the formation at the exit of the double envelope (32) of a series of drops (78), each drop (78) comprising a central core (80) formed of first solution (36) and a peripheral film (82). formed from the second solution (40). The method comprises dropping each drop (78) into a volume of gas at the outlet of the jacket (32) and immersing each drop (78) in a gelling solution (70) to form a gelled envelope. The ratio of the kinetic energy of the drop (78), to the square of its radius, when it comes into contact with the gelling solution (70) is greater than 1 J / m2.

FR1050262A 2010-01-15 2010-01-15 METHOD OF MANUFACTURING CAPSULES WITH CONTROLLED FALL HEIGHT. Active FR2955257B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1050262A FR2955257B1 (en) 2010-01-15 2010-01-15 METHOD OF MANUFACTURING CAPSULES WITH CONTROLLED FALL HEIGHT.
PCT/FR2011/050064 WO2011086331A2 (en) 2010-01-15 2011-01-13 Method for manufacturing capsules having controlled head

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1050262A FR2955257B1 (en) 2010-01-15 2010-01-15 METHOD OF MANUFACTURING CAPSULES WITH CONTROLLED FALL HEIGHT.

Publications (2)

Publication Number Publication Date
FR2955257A1 FR2955257A1 (en) 2011-07-22
FR2955257B1 true FR2955257B1 (en) 2012-06-01

Family

ID=42226643

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1050262A Active FR2955257B1 (en) 2010-01-15 2010-01-15 METHOD OF MANUFACTURING CAPSULES WITH CONTROLLED FALL HEIGHT.

Country Status (2)

Country Link
FR (1) FR2955257B1 (en)
WO (1) WO2011086331A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2978900B1 (en) * 2011-08-11 2014-02-21 Capsum FOOD CAPSULES
FR2986165B1 (en) 2012-01-31 2015-07-24 Capsum PROCESS FOR PREPARING RIGIDIFIED CAPSULES
US20150335586A1 (en) 2014-05-20 2015-11-26 R.P. Scherer Technologies, Llc Capsule dispensing container
FR3054127B1 (en) 2016-07-20 2019-08-16 Capsum CAPSULE SERIES AND MANUFACTURING METHOD, COSMETIC COMPOSITION, AND COSMETIC TREATMENT.
CN109875116B (en) * 2017-12-06 2022-01-25 贵州中烟工业有限责任公司 Cigarette explodes pearl processing equipment and local accelerating device of circulating liquid thereof
CA3202526A1 (en) * 2020-11-20 2022-05-27 The Governing Council Of The University Of Toronto Skin spheroids and process of preparation and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL79052A0 (en) * 1986-06-06 1986-11-30 Univ Ramot Device and process for production of alginate-shell beads containing biologically active material
US6056992A (en) 1988-06-02 2000-05-02 Campbell Soup Company Encapsulated additives
JP3313124B2 (en) * 1991-07-31 2002-08-12 森下仁丹株式会社 SEAMLESS CAPSULES CONTAINING A HYDROPHILIC SUBSTANCE AND PROCESS FOR PRODUCING THE SAME
US5650232A (en) * 1994-10-07 1997-07-22 Warner-Lambert Company Method for making seamless capsules
ATE544440T1 (en) * 2000-08-17 2012-02-15 Chugai Pharmaceutical Co Ltd METHOD FOR PRODUCING A SEAMLESS CAPSULE
JP4051075B2 (en) * 2003-11-07 2008-02-20 フロイント産業株式会社 Seamless capsule manufacturing method, seamless capsule manufacturing apparatus, and seamless capsule
WO2006136196A1 (en) * 2005-06-21 2006-12-28 V. Mane Fils Gellan seamless breakable capsule and process for manufacturing thereof
US7442439B2 (en) * 2005-12-28 2008-10-28 Kimberly-Clark Worldwide, Inc. Microencapsulated heat delivery vehicles

Also Published As

Publication number Publication date
WO2011086331A2 (en) 2011-07-21
WO2011086331A3 (en) 2011-09-09
FR2955257A1 (en) 2011-07-22

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