FR2936255B1 - Modulateurs de fzd2 dans le traitement de l'alopecie - Google Patents

Modulateurs de fzd2 dans le traitement de l'alopecie

Info

Publication number
FR2936255B1
FR2936255B1 FR0856315A FR0856315A FR2936255B1 FR 2936255 B1 FR2936255 B1 FR 2936255B1 FR 0856315 A FR0856315 A FR 0856315A FR 0856315 A FR0856315 A FR 0856315A FR 2936255 B1 FR2936255 B1 FR 2936255B1
Authority
FR
France
Prior art keywords
alopecia
treatment
fzd2
modulators
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0856315A
Other languages
English (en)
Other versions
FR2936255A1 (fr
Inventor
Sandrine Rethore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Galderma Research and Development SNC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Research and Development SNC filed Critical Galderma Research and Development SNC
Priority to FR0856315A priority Critical patent/FR2936255B1/fr
Priority to US13/120,103 priority patent/US20110224243A1/en
Priority to EP09747890A priority patent/EP2329036A1/fr
Priority to CA2737993A priority patent/CA2737993A1/fr
Priority to PCT/FR2009/051770 priority patent/WO2010031979A1/fr
Publication of FR2936255A1 publication Critical patent/FR2936255A1/fr
Application granted granted Critical
Publication of FR2936255B1 publication Critical patent/FR2936255B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR0856315A 2008-09-19 2008-09-19 Modulateurs de fzd2 dans le traitement de l'alopecie Expired - Fee Related FR2936255B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0856315A FR2936255B1 (fr) 2008-09-19 2008-09-19 Modulateurs de fzd2 dans le traitement de l'alopecie
US13/120,103 US20110224243A1 (en) 2008-09-19 2009-09-21 FZD2 Molulators in the Treatment of Alopecia
EP09747890A EP2329036A1 (fr) 2008-09-19 2009-09-21 Modulateurs de fzd2 dans le traitement de l'alopecie
CA2737993A CA2737993A1 (fr) 2008-09-19 2009-09-21 Modulateurs de fzd2 dans le traitement de l'alopecie
PCT/FR2009/051770 WO2010031979A1 (fr) 2008-09-19 2009-09-21 Modulateurs de fzd2 dans le traitement de l'alopecie

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0856315A FR2936255B1 (fr) 2008-09-19 2008-09-19 Modulateurs de fzd2 dans le traitement de l'alopecie

Publications (2)

Publication Number Publication Date
FR2936255A1 FR2936255A1 (fr) 2010-03-26
FR2936255B1 true FR2936255B1 (fr) 2010-10-15

Family

ID=40568269

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0856315A Expired - Fee Related FR2936255B1 (fr) 2008-09-19 2008-09-19 Modulateurs de fzd2 dans le traitement de l'alopecie

Country Status (5)

Country Link
US (1) US20110224243A1 (fr)
EP (1) EP2329036A1 (fr)
CA (1) CA2737993A1 (fr)
FR (1) FR2936255B1 (fr)
WO (1) WO2010031979A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102827287B (zh) 2005-10-31 2015-08-12 昂考梅德药品有限公司 用于诊断和治疗癌症的组合物和方法
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
JP5792621B2 (ja) 2008-09-26 2015-10-14 オンコメッド ファーマシューティカルズ インコーポレイテッド frizzled結合剤およびその使用
US8551789B2 (en) 2010-04-01 2013-10-08 OncoMed Pharmaceuticals Frizzled-binding agents and their use in screening for WNT inhibitors
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Wnt拮抗劑及治療和篩選方法
AU2012271413B2 (en) 2011-06-17 2017-07-13 President And Fellows Of Harvard College Frizzled 2 as a target for therapeutic antibodies in the treatment of cancer
JP2015536933A (ja) 2012-10-23 2015-12-24 オンコメッド ファーマシューティカルズ インコーポレイテッド Wnt経路結合剤を用いて神経内分泌腫瘍を処置する方法
WO2014121196A1 (fr) 2013-02-04 2014-08-07 Oncomed Pharmaceuticals, Inc. Méthodes et surveillance de traitement par un inhibiteur de la voie wnt
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5301201A (en) * 2000-03-31 2001-10-15 Gen Hospital Corp Methods of modulating hair growth
WO2005084223A2 (fr) * 2004-02-27 2005-09-15 The General Hospital Corporation Procedes et compositions pour la croissance capillaire

Also Published As

Publication number Publication date
EP2329036A1 (fr) 2011-06-08
CA2737993A1 (fr) 2010-03-25
US20110224243A1 (en) 2011-09-15
WO2010031979A1 (fr) 2010-03-25
FR2936255A1 (fr) 2010-03-26

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20130531