FR2914644B1 - Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane - Google Patents

Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane

Info

Publication number
FR2914644B1
FR2914644B1 FR0702544A FR0702544A FR2914644B1 FR 2914644 B1 FR2914644 B1 FR 2914644B1 FR 0702544 A FR0702544 A FR 0702544A FR 0702544 A FR0702544 A FR 0702544A FR 2914644 B1 FR2914644 B1 FR 2914644B1
Authority
FR
France
Prior art keywords
nitrobenzofuran
hydroxybenzoyl
butyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0702544A
Other languages
English (en)
Other versions
FR2914644A1 (fr
Inventor
Ousmanne Diouf
Thierry Durand
Stephane Lemeune
Jean Francois Marcoux
Natacha Frison
Laurent Larquetoux
Benoit Folleas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Finorga SAS
Original Assignee
Finorga SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finorga SAS filed Critical Finorga SAS
Priority to FR0702544A priority Critical patent/FR2914644B1/fr
Priority to PCT/FR2008/000472 priority patent/WO2008139057A2/fr
Publication of FR2914644A1 publication Critical patent/FR2914644A1/fr
Application granted granted Critical
Publication of FR2914644B1 publication Critical patent/FR2914644B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR0702544A 2007-04-06 2007-04-06 Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane Expired - Fee Related FR2914644B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR0702544A FR2914644B1 (fr) 2007-04-06 2007-04-06 Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane
PCT/FR2008/000472 WO2008139057A2 (fr) 2007-04-06 2008-04-04 Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl)-5-nitrobenzofurane

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0702544A FR2914644B1 (fr) 2007-04-06 2007-04-06 Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane

Publications (2)

Publication Number Publication Date
FR2914644A1 FR2914644A1 (fr) 2008-10-10
FR2914644B1 true FR2914644B1 (fr) 2009-06-05

Family

ID=38714169

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0702544A Expired - Fee Related FR2914644B1 (fr) 2007-04-06 2007-04-06 Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane

Country Status (2)

Country Link
FR (1) FR2914644B1 (fr)
WO (1) WO2008139057A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100135909A (ko) 2008-04-17 2010-12-27 사노피-아벤티스 심혈관성 입원 또는 사망을 예방하는데 사용하기 위한 약제의 제조에 있어서의 드로네다론의 용도
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation
CN101948455B (zh) * 2010-10-18 2012-11-14 山东邹平大展新材料有限公司 一种2-正丁基-3-(4-羟基苯甲酰基)-5-硝基苯并呋喃的制备方法
CN110590722B (zh) * 2019-10-22 2022-11-04 温州大学 2-三氟甲基苯并呋喃衍生物的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
GB9416219D0 (en) * 1994-08-11 1994-10-05 Karobio Ab Receptor ligands
IL146389A0 (en) * 2001-11-08 2002-07-25 Isp Finetech Ltd Process for the preparation of dronedarone
FR2864536B1 (fr) * 2003-12-24 2006-03-17 Clariant France Sa Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
FR2877341A1 (fr) * 2004-11-02 2006-05-05 Rhodia Chimie Sa Procede d'acylation d'un compose aromatique

Also Published As

Publication number Publication date
WO2008139057A2 (fr) 2008-11-20
FR2914644A1 (fr) 2008-10-10
WO2008139057A3 (fr) 2009-01-08

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20111230