FR2871698B1 - Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse - Google Patents

Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse

Info

Publication number
FR2871698B1
FR2871698B1 FR0406611A FR0406611A FR2871698B1 FR 2871698 B1 FR2871698 B1 FR 2871698B1 FR 0406611 A FR0406611 A FR 0406611A FR 0406611 A FR0406611 A FR 0406611A FR 2871698 B1 FR2871698 B1 FR 2871698B1
Authority
FR
France
Prior art keywords
association
oily phase
spray composition
pharmaceutical assets
assets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0406611A
Other languages
English (en)
Other versions
FR2871698A1 (fr
Inventor
Nathalie Willcox
Sandrine Orsoni
Laurent Fredon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma SA
Original Assignee
Galderma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma SA filed Critical Galderma SA
Priority to FR0406611A priority Critical patent/FR2871698B1/fr
Priority to US10/950,650 priority patent/US20050281749A1/en
Priority to JP2007515906A priority patent/JP2008502645A/ja
Priority to CNA2005800200581A priority patent/CN101541328A/zh
Priority to AU2005253733A priority patent/AU2005253733A1/en
Priority to EP05770876A priority patent/EP1758586B1/fr
Priority to AT05770876T priority patent/ATE518542T1/de
Priority to BRPI0511389-0A priority patent/BRPI0511389A/pt
Priority to RU2007101519/15A priority patent/RU2007101519A/ru
Priority to MXPA06014397A priority patent/MXPA06014397A/es
Priority to CA002567683A priority patent/CA2567683A1/fr
Priority to PCT/EP2005/007972 priority patent/WO2005123090A1/fr
Priority to ES05770876T priority patent/ES2370907T3/es
Priority to ARP050102467A priority patent/AR049307A1/es
Publication of FR2871698A1 publication Critical patent/FR2871698A1/fr
Priority to ZA200700306A priority patent/ZA200700306B/xx
Application granted granted Critical
Publication of FR2871698B1 publication Critical patent/FR2871698B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
FR0406611A 2004-06-17 2004-06-17 Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse Expired - Fee Related FR2871698B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR0406611A FR2871698B1 (fr) 2004-06-17 2004-06-17 Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse
US10/950,650 US20050281749A1 (en) 2004-06-17 2004-09-28 Sprayable compositions comprising a combination of pharmaceutical actives and an oily phase
PCT/EP2005/007972 WO2005123090A1 (fr) 2004-06-17 2005-06-15 Composition sous forme pulverisee comprenant une combinaison d'un corticoide et d'un derive de la vitamine d dans une phase huileuse
AU2005253733A AU2005253733A1 (en) 2004-06-17 2005-06-15 Composition in spray form comprising a combination of a corticoid and a vitamin D derivative in an oily phase
EP05770876A EP1758586B1 (fr) 2004-06-17 2005-06-15 Composition sous forme de spray comprenant une combinaison d'un corticoide et d'un derive de la vitamine d dans une phase huileuse
AT05770876T ATE518542T1 (de) 2004-06-17 2005-06-15 Zusammensetzung in sprayform mit einer kombination aus einem kortikoid und einem vitamin-d-derivat in einer ölphase
BRPI0511389-0A BRPI0511389A (pt) 2004-06-17 2005-06-15 composição e seu uso
RU2007101519/15A RU2007101519A (ru) 2004-06-17 2005-06-15 Композиция в форме спрея, содержащая в масляной фазе сочетание кортикоида и производного витамина d
JP2007515906A JP2008502645A (ja) 2004-06-17 2005-06-15 油性相中にコルチコイドとビタミンｄ誘導体との組み合わせを含むスプレー形態の組成物
CA002567683A CA2567683A1 (fr) 2004-06-17 2005-06-15 Composition sous forme pulverisee comprenant une combinaison d'un corticoide et d'un derive de la vitamine d dans une phase huileuse
CNA2005800200581A CN101541328A (zh) 2004-06-17 2005-06-15 在油相中含有类皮质激素和维生素d衍生物的组合的喷雾剂形式组合物
ES05770876T ES2370907T3 (es) 2004-06-17 2005-06-15 Composición en forma de pulverizador que comprende una combinación de un corticoide y un derivado de vitamina d en una fase oleosa.
MXPA06014397A MXPA06014397A (es) 2004-06-17 2005-06-15 Composicion en forma de aerosol que comprende una combinacion de un corticoide y un derivado de la vitamina d en una fase aceitosa.
ARP050102467A AR049307A1 (es) 2004-06-17 2005-06-16 Composicion en forma de spray que comprende un corticoide y un derivado de vitamina d, y una fase aceitosa
ZA200700306A ZA200700306B (en) 2004-06-17 2007-01-11 Composition in spray form comprising a combination of a corticoid and a vitamin D derivative in an oily phase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0406611A FR2871698B1 (fr) 2004-06-17 2004-06-17 Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse

Publications (2)

Publication Number Publication Date
FR2871698A1 FR2871698A1 (fr) 2005-12-23
FR2871698B1 true FR2871698B1 (fr) 2008-07-04

Family

ID=34945642

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0406611A Expired - Fee Related FR2871698B1 (fr) 2004-06-17 2004-06-17 Composition sous forme de spray comprenant une association d'actifs pharmaceutiques et une phase huileuse

Country Status (8)

Country Link
US (1) US20050281749A1 (fr)
CN (1) CN101541328A (fr)
AR (1) AR049307A1 (fr)
AT (1) ATE518542T1 (fr)
ES (1) ES2370907T3 (fr)
FR (1) FR2871698B1 (fr)
RU (1) RU2007101519A (fr)
ZA (1) ZA200700306B (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US20080138296A1 (en) * 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
EP1556009B2 (fr) 2002-10-25 2021-07-21 Foamix Pharmaceuticals Ltd. Mousse cosmetique et pharmaceutique
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
FR2871700B1 (fr) * 2004-06-17 2006-11-17 Galderma Sa Composition sous forme de spray comprenant une association d'actifs pharmaceutiques, une phase alcoolique, et une phase huileuse
US20080153786A1 (en) * 2006-05-22 2008-06-26 Galderma S.A. Controlled release of drugs into/through the skin
US20070036731A1 (en) * 2005-08-13 2007-02-15 Collegium Pharmaceutical, Inc. Topical Delivery with a Carrier Fluid
FR2893845B1 (fr) * 2005-11-30 2010-10-29 Galderma Sa Composition sous forme de spray comprenant un corticoide et une phase huileuse
US20080260655A1 (en) * 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
EP1970048A1 (fr) * 2007-03-15 2008-09-17 Drug Delivery Solutions Limited Composition topique de type polyaphron avec de la vitamine D
US10265265B2 (en) 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
EP2008651A1 (fr) 2007-06-26 2008-12-31 Drug Delivery Solutions Limited Patch bioérodable
FR2917976B1 (fr) * 2007-06-29 2010-05-28 Galderma Sa Composition dermatologique comprenant des vehicules lipidiques de calcitriol, son procede de preparation et son utilisation
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2009090495A2 (fr) 2007-12-07 2009-07-23 Foamix Ltd. Vecteurs moussants siliconés à base d'huile et de liquide, et formulations
GB0814713D0 (en) * 2008-08-12 2008-09-17 Thornton & Ross Ltd A method and composition for the control of ectoparasites
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
WO2011013008A2 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes à base d'agents non tensioactifs non polymères, mousses légères, et leurs utilisations
WO2011013009A2 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes non tensioactives, mousses légères, et leurs utilisations
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
US10029013B2 (en) 2009-10-02 2018-07-24 Foamix Pharmaceuticals Ltd. Surfactant-free, water-free formable composition and breakable foams and their uses
KR101619077B1 (ko) 2010-06-11 2016-05-10 레오 파마 에이/에스 비타민 ｄ 유사체 및 코르티코스테로이드를 포함하는 약제학적 분무 조성물
US20120201871A1 (en) * 2011-02-07 2012-08-09 Professional Compounding Centers Of America, Ltd. Permeation enhancers with liposomes for topical formulations
US8906397B2 (en) 2011-02-07 2014-12-09 Professional Compounding Centers of America, Ltd Permeation enhancers for topical formulations
US8871811B2 (en) 2011-02-07 2014-10-28 Professional Compounding Centers of America, Ltd Permeation enhancers for topical formulations
HUE045467T2 (hu) 2011-03-14 2020-01-28 Drug Delivery Solutions Ltd Szemészeti készítmény
IN2014DN11232A (fr) * 2012-07-06 2015-10-02 Leo Pharma As
ES2930347T3 (es) * 2014-05-06 2022-12-13 S I I T S R L Servizio Int Imballaggi Termosaldanti Composición oleosa pulverizable basada en vitaminas liposolubles del grupo D y uso de la misma
CN105193723A (zh) * 2015-10-23 2015-12-30 郑州泰丰制药有限公司 度骨化醇喷雾制剂及其制备方法
MX2020012139A (es) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Composiciones y metodos para tratar rosacea y acne.
EP3542788A1 (fr) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Composition topique comprenant calcipotriol et dipropionate de bétaméthasone

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US4610978A (en) * 1983-03-22 1986-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same
FR2709131B1 (fr) * 1993-08-18 1995-11-10 Cilag Laboratoire Dispositif de distribution d'une substance thérapeutique ou cosmétique dont le véhicule inerte est un polydiorganosiloxane volatil, et composition destinée à être utilisée dans le dispositif.
FR2737118B1 (fr) * 1995-07-28 1997-09-05 Oreal Composition dermatologique ou pharmaceutique, procede de preparation et utilisation
FR2738745B1 (fr) * 1995-09-15 1997-10-24 Cird Galderma Nouvelles compositions a base d'un melange synergetique entre au moins un ligand de vdr et un retinoide, et leurs utilisations
FR2740038B1 (fr) * 1995-10-20 1998-01-02 Lafon Labor Composition pour l'administration transdermique
IT1302275B1 (it) * 1998-09-25 2000-09-05 Giorgio Panin Formulazione di gel idrofobo a base di vitamina e acetato perapplicazione topica.
PT1178808E (pt) * 1999-04-23 2012-08-16 Leo Pharma As Composição farmacêutica não aquosa para utilização dérmica para o tratamento da psoríase compreendendo uma vitamina d, um corticosteróide e de um componente solvente
EP1331927B1 (fr) * 2000-10-27 2007-12-12 Leo Pharma A/S Composition topique contenant au moins une vitamine d ou un analogue de vitamine d et au moins un corticosteroide
FR2856301B1 (fr) * 2003-06-23 2007-08-03 Galderma Res & Dev Composition sous forme de spray comprenant un actif pharmaceutique, au moins un silicone volatile et une phase non polaire non volatile

Also Published As

Publication number Publication date
US20050281749A1 (en) 2005-12-22
RU2007101519A (ru) 2008-07-27
ATE518542T1 (de) 2011-08-15
FR2871698A1 (fr) 2005-12-23
AR049307A1 (es) 2006-07-12
ZA200700306B (en) 2007-12-27
CN101541328A (zh) 2009-09-23
ES2370907T3 (es) 2011-12-23

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Effective date: 20130228