FR2862645B1 - Composes antidiabetiques contenant des derives benzofuranes, benzothiophenes - Google Patents
Composes antidiabetiques contenant des derives benzofuranes, benzothiophenesInfo
- Publication number
- FR2862645B1 FR2862645B1 FR0313612A FR0313612A FR2862645B1 FR 2862645 B1 FR2862645 B1 FR 2862645B1 FR 0313612 A FR0313612 A FR 0313612A FR 0313612 A FR0313612 A FR 0313612A FR 2862645 B1 FR2862645 B1 FR 2862645B1
- Authority
- FR
- France
- Prior art keywords
- benzothiophenic
- derivatives
- compounds containing
- antidiabetic compounds
- containing benzofuran
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0313612A FR2862645B1 (fr) | 2003-11-20 | 2003-11-20 | Composes antidiabetiques contenant des derives benzofuranes, benzothiophenes |
JP2006540215A JP4786545B2 (ja) | 2003-11-20 | 2004-10-26 | ベンゾチオフェン誘導体を含む抗糖尿病化合物 |
CNA2004800342573A CN1882563A (zh) | 2003-11-20 | 2004-10-26 | 包含苯并呋喃和苯并噻吩衍生物的抗糖尿病化合物 |
AT04790858T ATE398116T1 (de) | 2003-11-20 | 2004-10-26 | Benzothiophenderivate enthaltende antidiabetische verbindungen |
BRPI0416675-2A BRPI0416675A (pt) | 2003-11-20 | 2004-10-26 | compostos antidiabéticos que compreendem derivados de benzofurano e de benzotiofeno |
PCT/EP2004/012075 WO2005054225A1 (fr) | 2003-11-20 | 2004-10-26 | Composes antidiabetiques comprenant des derives de benzofurane et de benzothiophene |
EP04790858A EP1685121B1 (fr) | 2003-11-20 | 2004-10-26 | Composes antidiabetiques comprenant des derives de benzothiophene |
US10/580,033 US7375130B2 (en) | 2003-11-20 | 2004-10-26 | Antidiabetic compounds comprising benzofuran and benzothiophene derivatives |
ES04790858T ES2308263T3 (es) | 2003-11-20 | 2004-10-26 | Compuestos antidiabeticos que comprenden derivados de benzotiofeno. |
DE602004014401T DE602004014401D1 (de) | 2003-11-20 | 2004-10-26 | Benzothiophenderivate enthaltende antidiabetische verbindungen |
CA2546647A CA2546647C (fr) | 2003-11-20 | 2004-10-26 | Composes antidiabetiques comprenant des derives de benzofurane et de benzothiophene |
AU2004295029A AU2004295029B2 (en) | 2003-11-20 | 2004-10-26 | Antidiabetic compounds comprising benzofuran and benzothiophene derivatives |
KR1020067009679A KR20060101491A (ko) | 2003-11-20 | 2004-10-26 | 벤조퓨란 및 벤조티오펜 유도체를 포함하는 항당뇨 화합물 |
ARP040104273A AR046644A1 (es) | 2003-11-20 | 2004-11-19 | Compuestos antidiabeticos que contienen derivados de benzotiofeno y benzofurano,composiciones farmaceuticas que los contienen y procedimiento de prepararcion de los mismos |
ZA200605023A ZA200605023B (en) | 2003-11-20 | 2006-06-19 | Antidiabetic compounds comprising benzofuran and benzothiophene derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0313612A FR2862645B1 (fr) | 2003-11-20 | 2003-11-20 | Composes antidiabetiques contenant des derives benzofuranes, benzothiophenes |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2862645A1 FR2862645A1 (fr) | 2005-05-27 |
FR2862645B1 true FR2862645B1 (fr) | 2007-06-22 |
Family
ID=34531150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0313612A Expired - Fee Related FR2862645B1 (fr) | 2003-11-20 | 2003-11-20 | Composes antidiabetiques contenant des derives benzofuranes, benzothiophenes |
Country Status (15)
Country | Link |
---|---|
US (1) | US7375130B2 (fr) |
EP (1) | EP1685121B1 (fr) |
JP (1) | JP4786545B2 (fr) |
KR (1) | KR20060101491A (fr) |
CN (1) | CN1882563A (fr) |
AR (1) | AR046644A1 (fr) |
AT (1) | ATE398116T1 (fr) |
AU (1) | AU2004295029B2 (fr) |
BR (1) | BRPI0416675A (fr) |
CA (1) | CA2546647C (fr) |
DE (1) | DE602004014401D1 (fr) |
ES (1) | ES2308263T3 (fr) |
FR (1) | FR2862645B1 (fr) |
WO (1) | WO2005054225A1 (fr) |
ZA (1) | ZA200605023B (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2862646B1 (fr) * | 2003-11-20 | 2006-02-24 | Merck Sante Sas | Nouveaux composes antidiabetiques contenant des derives benzofuranes, benzothiophenes |
GB0506133D0 (en) * | 2005-03-24 | 2005-05-04 | Sterix Ltd | Compound |
AU2011202542A1 (en) | 2010-07-14 | 2012-02-02 | Indian Institute Of Science | Benzothiophene carboxamide compounds, composition and applications thereof |
WO2014187343A1 (fr) * | 2013-05-22 | 2014-11-27 | 四川海思科制药有限公司 | Dérivé benzofurane, son procédé de préparation, et son application médicale |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3592907A (en) * | 1968-03-06 | 1971-07-13 | Dow Chemical Co | Substituted benzo(b)thiophene compositions |
US3989718A (en) * | 1975-05-06 | 1976-11-02 | Eli Lilly And Company | [1]Benzothieno[3,2-b]furans |
ZA858748B (en) * | 1984-12-10 | 1987-06-24 | Warner Lambert Co | Novel benzothiophenes and benzofurans having antiallergy activity |
IE64995B1 (en) * | 1987-07-14 | 1995-09-20 | Warner Lambert Co | Novel benzothiophenes having antiallergic activity and both novel and other selected benzothiophenes having activity for treating acute respiratory distress syndrome |
WO1995005170A1 (fr) * | 1993-08-13 | 1995-02-23 | Warner-Lambert Company | Methodes d'inhibition du vih et de son activation |
US5350748A (en) * | 1993-08-18 | 1994-09-27 | Warner-Lambert Company | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion |
US5908859A (en) * | 1997-08-11 | 1999-06-01 | Eli Lilly And Company | Benzothiophenes for inhibiting hyperlipidemia |
TR200003333T2 (tr) * | 1998-05-12 | 2001-02-21 | American Home Products Corporation | Ensülin direngenliği ve hiperglisemi tedavisinde yararlı benzotiyofenler |
AU3791799A (en) * | 1998-05-12 | 1999-11-29 | American Home Products Corporation | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
US6436965B1 (en) * | 2000-03-02 | 2002-08-20 | Merck Frosst Canada & Co. | PDE IV inhibiting amides, compositions and methods of treatment |
US20040259926A1 (en) * | 2003-06-05 | 2004-12-23 | Bruendl Michelle M. | 3-Aryloxy and 3-heteroaryloxy substituted benzo[b]thiophenes as therapeutic agents |
FR2862646B1 (fr) * | 2003-11-20 | 2006-02-24 | Merck Sante Sas | Nouveaux composes antidiabetiques contenant des derives benzofuranes, benzothiophenes |
-
2003
- 2003-11-20 FR FR0313612A patent/FR2862645B1/fr not_active Expired - Fee Related
-
2004
- 2004-10-26 EP EP04790858A patent/EP1685121B1/fr active Active
- 2004-10-26 CN CNA2004800342573A patent/CN1882563A/zh active Pending
- 2004-10-26 DE DE602004014401T patent/DE602004014401D1/de active Active
- 2004-10-26 KR KR1020067009679A patent/KR20060101491A/ko not_active Application Discontinuation
- 2004-10-26 ES ES04790858T patent/ES2308263T3/es active Active
- 2004-10-26 WO PCT/EP2004/012075 patent/WO2005054225A1/fr active IP Right Grant
- 2004-10-26 JP JP2006540215A patent/JP4786545B2/ja not_active Expired - Fee Related
- 2004-10-26 US US10/580,033 patent/US7375130B2/en not_active Expired - Fee Related
- 2004-10-26 AU AU2004295029A patent/AU2004295029B2/en not_active Ceased
- 2004-10-26 BR BRPI0416675-2A patent/BRPI0416675A/pt not_active Application Discontinuation
- 2004-10-26 AT AT04790858T patent/ATE398116T1/de not_active IP Right Cessation
- 2004-10-26 CA CA2546647A patent/CA2546647C/fr not_active Expired - Fee Related
- 2004-11-19 AR ARP040104273A patent/AR046644A1/es unknown
-
2006
- 2006-06-19 ZA ZA200605023A patent/ZA200605023B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2004295029A1 (en) | 2005-06-16 |
CA2546647A1 (fr) | 2005-06-16 |
DE602004014401D1 (de) | 2008-07-24 |
JP2007511552A (ja) | 2007-05-10 |
EP1685121B1 (fr) | 2008-06-11 |
WO2005054225A1 (fr) | 2005-06-16 |
ES2308263T3 (es) | 2008-12-01 |
AR046644A1 (es) | 2005-12-14 |
EP1685121A1 (fr) | 2006-08-02 |
ZA200605023B (en) | 2007-12-27 |
BRPI0416675A (pt) | 2007-02-13 |
AU2004295029B2 (en) | 2010-03-11 |
CN1882563A (zh) | 2006-12-20 |
KR20060101491A (ko) | 2006-09-25 |
ATE398116T1 (de) | 2008-07-15 |
CA2546647C (fr) | 2013-02-12 |
FR2862645A1 (fr) | 2005-05-27 |
US7375130B2 (en) | 2008-05-20 |
US20070078178A1 (en) | 2007-04-05 |
JP4786545B2 (ja) | 2011-10-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20080930 |