FR2781676B1 - Trimere du produit d'expression du gene env de hiv - Google Patents
Trimere du produit d'expression du gene env de hivInfo
- Publication number
- FR2781676B1 FR2781676B1 FR9810027A FR9810027A FR2781676B1 FR 2781676 B1 FR2781676 B1 FR 2781676B1 FR 9810027 A FR9810027 A FR 9810027A FR 9810027 A FR9810027 A FR 9810027A FR 2781676 B1 FR2781676 B1 FR 2781676B1
- Authority
- FR
- France
- Prior art keywords
- quarter
- gene expression
- expression product
- env gene
- hiv env
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 108700004025 env Genes Proteins 0.000 title 1
- 101150030339 env gene Proteins 0.000 title 1
- 230000014509 gene expression Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9810027A FR2781676B1 (fr) | 1998-07-31 | 1998-07-31 | Trimere du produit d'expression du gene env de hiv |
EP99934806A EP1100926A1 (fr) | 1998-07-31 | 1999-07-29 | TRIMERE DU PRODUIT D'EXPRESSION DU GENE $i(ENV) DE HIV |
PCT/FR1999/001871 WO2000008167A1 (fr) | 1998-07-31 | 1999-07-29 | Trimere du produit d'expression du gene env de hiv |
US09/744,659 US6737067B1 (en) | 1998-07-31 | 1999-07-29 | Trimer of HIV env gene expression product |
CA002338020A CA2338020A1 (fr) | 1998-07-31 | 1999-07-29 | Trimere du produit d'expression du gene env de hiv |
AU50459/99A AU5045999A (en) | 1998-07-31 | 1999-07-29 | Trimer of HIV (ENV) gene expression product |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9810027A FR2781676B1 (fr) | 1998-07-31 | 1998-07-31 | Trimere du produit d'expression du gene env de hiv |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2781676A1 FR2781676A1 (fr) | 2000-02-04 |
FR2781676B1 true FR2781676B1 (fr) | 2004-04-02 |
Family
ID=9529397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9810027A Expired - Fee Related FR2781676B1 (fr) | 1998-07-31 | 1998-07-31 | Trimere du produit d'expression du gene env de hiv |
Country Status (6)
Country | Link |
---|---|
US (1) | US6737067B1 (fr) |
EP (1) | EP1100926A1 (fr) |
AU (1) | AU5045999A (fr) |
CA (1) | CA2338020A1 (fr) |
FR (1) | FR2781676B1 (fr) |
WO (1) | WO2000008167A1 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6861253B2 (en) | 2001-01-05 | 2005-03-01 | Aventis Pasteur S.A. | Polypeptide inducing antibodies neutralizing HIV |
DE60216958T2 (de) | 2001-10-05 | 2007-10-04 | Sanofi Pasteur | Eine den gp41-zwischenzustand imitierende struktur bildendes polypeptid-antigen |
FR2830534B1 (fr) * | 2001-10-05 | 2004-10-01 | Aventis Pasteur | Antigene polypeptidique formant une structure mimant l'etat intermediaire de gp41. |
US7056519B2 (en) | 2002-05-17 | 2006-06-06 | Aventis Pasteur S.A. | Methods for inducing HIV-neutralizing antibodies |
GB0422439D0 (en) * | 2004-10-08 | 2004-11-10 | European Molecular Biology Lab Embl | Inhibitors of infection |
DK1831247T3 (da) * | 2004-12-29 | 2009-10-12 | Seattle Biomedical Res Inst | Hetero-oligomere HIV-kappeproteiner |
EP2040746A4 (fr) * | 2006-06-19 | 2009-12-16 | Progenics Pharm Inc | Procedes de recuperation de formules stabilisees de trimeres de proteines d'enveloppe (env) retrovirale |
EP2040747A4 (fr) * | 2006-06-19 | 2010-08-25 | Progenics Pharm Inc | Protéines env vih trimériques solubles stabilisées et leurs utilisations |
WO2008063331A2 (fr) * | 2006-10-23 | 2008-05-29 | Progenics Pharmaceuticals, Inc. | Polypeptides d'enveloppe gp140 modifiés en provenance d'isolats du vih-1, compositions, complexes trimériques et utilisations de ceux-ci |
EP2550362B1 (fr) | 2010-03-25 | 2017-01-04 | Oregon Health&Science University | Glycoprotéines du cmv et vecteurs recombinés |
CA2832109C (fr) | 2011-06-10 | 2021-07-06 | Oregon Health & Science University | Glycoproteines de cmv et vecteurs recombinants cmv |
US20150190501A1 (en) * | 2011-09-12 | 2015-07-09 | Imperial Innovations Limited | Methods and compositions for raising an immune response to hiv |
AU2012216792A1 (en) | 2011-09-12 | 2013-03-28 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies |
US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
EP2679596B1 (fr) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | Variante de la protéine env du VIH-1 |
US20150065381A1 (en) | 2013-09-05 | 2015-03-05 | International Aids Vaccine Initiative | Methods of identifying novel hiv-1 immunogens |
EP2873423B1 (fr) | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Trimères de glycoprotéines d'enveloppe du vih -1 soluble |
EP3069730A3 (fr) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Trimères de glycoprotéines de l'enveloppe du vih-1 soluble |
EP3072901A1 (fr) | 2015-03-23 | 2016-09-28 | International Aids Vaccine Initiative | Trimères de glycoprotéines de l'enveloppe du vih-1 soluble |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5122468A (en) * | 1988-08-16 | 1992-06-16 | Akzo N.V. | Hut-78 cell lines infected with HTLV-III which secrete gp160 |
FR2692898B1 (fr) * | 1992-06-30 | 1995-06-02 | Centre Nat Rech Scient | Procédé d'obtention de protéines membranaires, et utilisation de ces protéines dans un but de diagnostic ou de vaccination. |
WO1994016081A1 (fr) * | 1993-01-16 | 1994-07-21 | Manfred Schawaller | Procede permettant d'obtenir des domaines natifs de proteines virales membranaires, leur utilisation, notamment comme vaccin contre le vih |
EP1019511A2 (fr) * | 1997-10-01 | 2000-07-19 | Dana-Farber Cancer Institute | Stabilisation des glycoproteines trimeres d'enveloppe au moyen de liaisons bisulfure introduites dans un ectodomaine de la glycoproteine gp41 |
-
1998
- 1998-07-31 FR FR9810027A patent/FR2781676B1/fr not_active Expired - Fee Related
-
1999
- 1999-07-29 WO PCT/FR1999/001871 patent/WO2000008167A1/fr not_active Application Discontinuation
- 1999-07-29 CA CA002338020A patent/CA2338020A1/fr not_active Abandoned
- 1999-07-29 US US09/744,659 patent/US6737067B1/en not_active Expired - Fee Related
- 1999-07-29 AU AU50459/99A patent/AU5045999A/en not_active Abandoned
- 1999-07-29 EP EP99934806A patent/EP1100926A1/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1100926A1 (fr) | 2001-05-23 |
US6737067B1 (en) | 2004-05-18 |
WO2000008167A1 (fr) | 2000-02-17 |
FR2781676A1 (fr) | 2000-02-04 |
AU5045999A (en) | 2000-02-28 |
CA2338020A1 (fr) | 2000-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CA | Change of address | ||
CD | Change of name or company name | ||
RT | Complete renunciation | ||
ST | Notification of lapse |
Effective date: 20060331 |