FR2759910A1 - Cosmetic and dermo-pharmaceutical use of extracts of Kigelia africana - Google Patents
Cosmetic and dermo-pharmaceutical use of extracts of Kigelia africana Download PDFInfo
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- FR2759910A1 FR2759910A1 FR9702279A FR9702279A FR2759910A1 FR 2759910 A1 FR2759910 A1 FR 2759910A1 FR 9702279 A FR9702279 A FR 9702279A FR 9702279 A FR9702279 A FR 9702279A FR 2759910 A1 FR2759910 A1 FR 2759910A1
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- 239000002537 cosmetic Substances 0.000 title claims abstract description 36
- 239000000284 extract Substances 0.000 title claims abstract description 36
- 244000062767 Kigelia africana Species 0.000 title claims abstract description 16
- 235000002329 Kigelia pinnata Nutrition 0.000 title claims abstract description 16
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- 208000024963 hair loss Diseases 0.000 claims abstract description 7
- 239000000203 mixture Substances 0.000 claims description 28
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- 239000000419 plant extract Substances 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims description 2
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- 239000013598 vector Substances 0.000 claims description 2
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- 229920002683 Glycosaminoglycan Polymers 0.000 description 2
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- 229930182478 glucoside Natural products 0.000 description 2
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 2
- IQPNAANSBPBGFQ-UHFFFAOYSA-N luteolin Chemical compound C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(O)C(O)=C1 IQPNAANSBPBGFQ-UHFFFAOYSA-N 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- INLFWQCRAJUDCR-IQVMEADQSA-N (1R,2S,4S,5'S,6R,7S,8R,9S,12S,13S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane] Chemical compound O([C@@H]1[C@@H]([C@]2(CC[C@@H]3[C@@]4(C)CCCCC4CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@H](C)CO1 INLFWQCRAJUDCR-IQVMEADQSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- 239000004166 Lanolin Substances 0.000 description 1
- 241000201976 Polycarpon Species 0.000 description 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 1
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- 239000003435 antirheumatic agent Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
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- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
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- 229960002154 guar gum Drugs 0.000 description 1
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- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 229940039717 lanolin Drugs 0.000 description 1
- 235000019388 lanolin Nutrition 0.000 description 1
- 239000008141 laxative Substances 0.000 description 1
- LRDGATPGVJTWLJ-UHFFFAOYSA-N luteolin Natural products OC1=CC(O)=CC(C=2OC3=CC(O)=CC(O)=C3C(=O)C=2)=C1 LRDGATPGVJTWLJ-UHFFFAOYSA-N 0.000 description 1
- 235000009498 luteolin Nutrition 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
La présente invention concerne des compositions cosmétiques ou dermopharmaceutiques pour le traitement et le soin du corps contenant des extraits de Kigelia africana. Les parties du corps intéressées sont plus particulièrement le buste des adolescentes et des femmes jeunes ou âgées, la
chevelure et le système pileux des hommes et des femmes.The present invention relates to cosmetic or dermopharmaceutical compositions for the treatment and care of the body containing extracts of Kigelia africana. The parts of the body concerned are more particularly the bust of adolescent girls and young or old women, the
hair and hair system of men and women.
Différentes parties du Kigelia africana, telles que les racines, les feuilles, les écorces ou les fruits, sont utilisées dans la médecine traditionnelle africaine. Different parts of Kigelia africana, such as roots, leaves, bark or fruit, are used in traditional African medicine.
On leur attribue des propriétés diurétiques, antirhumatismales, purgatives, reconstituantes mais aussi des vertus pour tous les problèmes féminins.They are credited with diuretic, antirheumatic, purgative, restorative properties but also virtues for all female problems.
L'analyse biochimique des organes de cet arbre et, plus particulièrement celle de la pulpe du fruit, révèle la présence de flavonoïdes : 6 hydroxyluteoline 7-0- glucoside, luteoliné, 7-0- glucoside, luteoline et quercetine. D'autres sapogénines steroïdiques ont également été mis en évidence par chromatographie liquide à haute pression. La plante est également très riche en tanins galliques. Biochemical analysis of the organs of this tree and, more particularly that of the fruit pulp, reveals the presence of flavonoids: 6 hydroxyluteoline 7-0- glucoside, luteolin, 7-0- glucoside, luteoline and quercetin. Other steroid sapogenins have also been demonstrated by high pressure liquid chromatography. The plant is also very rich in gallic tannins.
On a maintenant découvert que l'on peut obtenir, à partir des fruits du
Kigelia africana, des extraits qui ont des propriétés cosmétiques très importantes et très spécifiques et qui se prêtent bien à la préparation de compositions cosmétiques pour le soin du corps.We have now discovered that it is possible to obtain, from the fruits of
Kigelia africana, extracts which have very important and very specific cosmetic properties and which lend themselves well to the preparation of cosmetic compositions for the care of the body.
Plus particulièrement, on a trouvé qu'à partir de ces fruits on peut obtenir des extraits ayant les propriétés:
- de raffermir le buste et d'augmenter sensiblement son volume
- d'inhiber l'alpha réductase et de ralentir la chute des cheveux
- de limiter la repousse des poils.More particularly, it has been found that from these fruits one can obtain extracts having the properties:
- firm the bust and significantly increase its volume
- inhibit alpha reductase and slow hair loss
- limit hair regrowth.
Les extraits de fruits de Kigelia africana, objets du présent brevet, peuvent donc être utilisés dans le domaine de la cosmétique, surtout pour les applications raffermissant et galbant le buste des femmes, contre la chute des cheveux pour les hommes et pour retarder la repousse des poils pour les femmes et les hommes. The extracts of fruits of Kigelia africana, objects of this patent, can therefore be used in the field of cosmetics, especially for applications strengthening and shaping the bust of women, against hair loss for men and to delay the regrowth of hairs for women and men.
Le Kigelia africana est un arbre de la famille des Bignonaceaes qui pousse en Afrique Centrale. C'est un arbre qui peut atteindre 15 mètres de hauteur. Son tronc et ses branches sont tortueuses. Les fruits sont caractéristiques, en forme de saucisson arrondi aux deux extrêmités et portant de nombreuses graines. La pulpe est très fibreuse. Kigelia africana is a tree in the Bignonaceae family that grows in Central Africa. It is a tree that can reach 15 meters in height. Its trunk and branches are tortuous. The fruits are characteristic, in the shape of a sausage rounded at both ends and bearing many seeds. The pulp is very fibrous.
Pour la préparation des extraits, on utilise la pulpe du fruit qui est découpée en très petits morceaux. On traite ensuite le substrat par ébullition dans de l'eau pendant plusieurs dizaines de minutes. Après filtration, on récupère un filtrat brun rouge de pH légèrement acide. Ce filtrat peut être concentré sous vide. Un conservateur, type butylène glycol ou propylèneglycol est ajouté. For the preparation of the extracts, the fruit pulp is used which is cut into very small pieces. The substrate is then treated by boiling in water for several tens of minutes. After filtration, a red brown filtrate with a slightly acidic pH is recovered. This filtrate can be concentrated under vacuum. A preservative, such as butylene glycol or propylene glycol is added.
Pour certaines applications, il peut s'avérer utile de préparer un extrait sec à partir de l'extrait liquide. Ceci peut être réalisé par les techniques classiques de séchage, d'évaporation, d'atomisation ou de lyophilisation. For certain applications, it may prove useful to prepare a dry extract from the liquid extract. This can be achieved by conventional drying, evaporation, atomization or lyophilization techniques.
L'exemple donné de fabrication de l'extrait n'est pas limitatif. Les améliorations, optimisations et modifications du procédé envisageable sont évidentes pour l'homme de l'art. A la place de la décoction, on peut employer la macération simple dans des solvants d'extraction tels que eau, mélange glycérine/eau, propylène glycol/eau, butylène glycol/eau ou dans des solvants organiques purs ou en mélange entre eux ou en mélange acqueux suivant leur miscibilité. On peut également employer des techniques à contre courant, la lixiviation, I'extraction à l'aide d'ultrasons, de CO2 supercritique, de micro-ondes associés ou non aux solvants. The example given for making the extract is not limiting. The improvements, optimizations and modifications of the conceivable process are obvious to a person skilled in the art. Instead of decoction, simple maceration can be used in extraction solvents such as water, glycerin / water mixture, propylene glycol / water, butylene glycol / water or in pure organic solvents or in mixture with one another or in aqueous mixture according to their miscibility. It is also possible to use countercurrent techniques, leaching, extraction using ultrasound, supercritical CO 2, microwaves, whether or not combined with solvents.
Les activités des extraits ainsi obtenus ont été mises en évidence par des méthodologies dérivées des techniques classiques normalement utilisées en cosmétologie. The activities of the extracts thus obtained have been demonstrated by methodologies derived from conventional techniques normally used in cosmetology.
L'activité raffermissante et galbante du buste est particulièrement intéressante quand elle est associée à des substances facilitant la tonicité et l'élasticité des tissus (extrait lipidique riche en céramides, extrait protéïque à pouvoir oxygraphique, mucopolysaccharide). The firming and shaping activity of the bust is particularly interesting when it is combined with substances that facilitate the tone and elasticity of the tissues (lipid extract rich in ceramides, protein extract with oxygen power, mucopolysaccharide).
L'activité antichute des cheveux et tonique capillaire est particulièrement intéressante quand elle est associée à des substances facilitant le bon état du cuir chevelu et celui du cheveu (minéraux, vitamines, céramides, extrait protéïque, mucopolysaccharide, acides de fleurs). The anti-hair loss and hair tonic activity is particularly advantageous when it is combined with substances facilitating the good condition of the scalp and that of the hair (minerals, vitamins, ceramides, protein extract, mucopolysaccharide, flower acids).
L'activité limitation de la repousse du poil est particulièrement intéressante quand elle est associée à des substances améliorant l'aspect de la peau. The activity limiting hair regrowth is particularly interesting when it is combined with substances improving the appearance of the skin.
Les extraits ainsi obtenus peuvent être employés dans les produits cosmétiques et dermopharmaceutiques de toute sorte. Leur utilisation principale est la cosmétique de soin, antichute de cheveux, limitant la repousse du poil, raffermissant le buste. En outre, les effets toniques de l'extrait, notamment sur la microcirculation, contribuent à une restructuration de l'épiderme, améliorent l'aspect de la peau et la souplesse du cheveu. The extracts thus obtained can be used in cosmetic and dermopharmaceutical products of all kinds. Their main use is cosmetic care, hair loss, limiting hair regrowth, firming the bust. In addition, the tonic effects of the extract, in particular on the microcirculation, contribute to a restructuring of the epidermis, improve the appearance of the skin and the suppleness of the hair.
L'extrait des fruits de Kigelia africana, objet du brevet, peut également trouver application dans les traitements de la peau acnéique. The patented extract of the fruits of Kigelia africana can also be used in the treatment of acne-prone skin.
Pour l'utilisation cosmétique, les extraits selon la présente invention peuvent être formulés sous forme galénique employée en cosmétique : crèmes, gels, lotions, laits, émulsions, solutions, onguents, pommades, huiles corporelles, lotions capillaires, shampoings, pulvérisateurs, lotions après rasage, savons, batons, crayons etc... qui les contiennent en quantités comprises entre 0,5 et 10 % en poids. For cosmetic use, the extracts according to the present invention can be formulated in galenical form used in cosmetics: creams, gels, lotions, milks, emulsions, solutions, ointments, ointments, body oils, hair lotions, shampoos, sprays, lotions after shaving, soaps, sticks, pencils etc ... which contain them in quantities between 0.5 and 10% by weight.
Pour la préparation de ces compositions cosmétiques, les extraits sont mélangés aux excipients généralement employés dans la technique cosmétique. For the preparation of these cosmetic compositions, the extracts are mixed with the excipients generally used in the cosmetic technique.
La forme de la composition cosmétique de la présente invention pourrait être une crème dans laquelle l'extrait est associé aux excipients couramment utilisés dans la cosmétologie et qui seraient compatibles avec celui-ci tel que la lanoline et ses dérivés. The form of the cosmetic composition of the present invention could be a cream in which the extract is associated with excipients commonly used in cosmetology and which would be compatible with it such as lanolin and its derivatives.
Les compositions cosmétiques peuvent être également présentées sous forme de gel dans les excipients appropriés tels que les esters de cellulose ou d'autres agents gélifiants, tels que le carbopol, la gomme guar, etc... The cosmetic compositions can also be presented in the form of a gel in appropriate excipients such as cellulose esters or other gelling agents, such as carbopol, guar gum, etc.
Les compositions cosmétiques suivant l'invention peuvent aussi prendre la forme de lotion ou solution dans laquelle l'extrait est dissout ou microdispersé dans une microémulsion. The cosmetic compositions according to the invention can also take the form of a lotion or solution in which the extract is dissolved or microdispersed in a microemulsion.
La forme des compositions cosmétiques suivant l'invention peut donc être une microdispersion de l'extrait dans un liquide contenant de l'eau, ainsi qu'un ou plusieurs agents tensioactifs. Ces dispersions présentent les caractères des microémulsions et ont pratiquement l'aspect de solutions vraies. The form of the cosmetic compositions according to the invention can therefore be a microdispersion of the extract in a liquid containing water, as well as one or more surfactants. These dispersions have the characteristics of microemulsions and practically have the appearance of true solutions.
Elles sont de préférence préparées extemporanément.They are preferably prepared immediately.
Ces microémulsions jouissent d'une bonne stabilité et peuvent être conservées pendant le temps nécessaire pour l'utilisation à des températures comprises entre 0 et 60 "C sans qu'il y ait sédimentation des constituants ou séparation des phases. These microemulsions have good stability and can be stored for the time necessary for use at temperatures between 0 and 60 "C without sedimentation of the constituents or separation of the phases.
II est possible d'incorporer les extraits de Kigelia africana décrits, dans des vecteurs comme les liposomes, les glycosphères, les chylomicrons, les macro-, micro- et nanoparticules ainsi que les macro-, micro- et nanocapsules, de les absorber sur des polymères organiques poudreux, les talcs, bentonites et autres supports minéraux. It is possible to incorporate the extracts of Kigelia africana described, in vectors such as liposomes, glycospheres, chylomicrons, macro-, micro- and nanoparticles as well as macro-, micro- and nanocapsules, to absorb them on powdery organic polymers, talcs, bentonites and other mineral supports.
Les compositions cosmétiques de l'invention peuvent aussi contenir des additifs ou des adjuvants usuels en cosmétologie, comme par exemple des agents antibactériens ou des parfums mais aussi des lipides d'extraction et/ou de synthèse, polymères gélifiants et viscosants, tensio-actifs et émulsifiants, principes actifs hydro -ou liposolubles, extraits de plantes, extraits tissulaires, extraits marins. The cosmetic compositions of the invention may also contain additives or adjuvants customary in cosmetology, such as for example antibacterial agents or perfumes but also extraction and / or synthetic lipids, gelling and viscosifying polymers, surfactants and emulsifiers, water-soluble or liposoluble active ingredients, plant extracts, tissue extracts, marine extracts.
Les compositions cosmétiques de la présente invention peuvent aussi comprendre d'autres principes actifs complémentaires choisis pour leur action, par exemple sur la nutrition cellulaire, la respiration cellulaire, I'hydratation et la régénération cellulaire, les traitements anti-séborrhéïques, ainsi que d'autres principes actifs ayant le même type d'action sur la tonicité cutanée, la chute du cheveu, la repousse du poil et le raffermissement du buste. The cosmetic compositions of the present invention can also comprise other complementary active principles chosen for their action, for example on cell nutrition, cellular respiration, hydration and cell regeneration, anti-seborrheic treatments, as well as other active ingredients with the same type of action on skin tone, hair loss, hair regrowth and firming of the bust.
Lorsque les compositions cosmétiques de la présente invention contiennent des principes actifs complémentaires, ceux-ci sont généralement présents dans la composition à une concentration suffisamment élevée pour qu'ils puissent exercer leur activité. When the cosmetic compositions of the present invention contain complementary active principles, these are generally present in the composition at a concentration high enough for them to be able to exercise their activity.
Les compositions cosmétiques de la présente invention sont de préférence à utiliser quotidiennement en les appliquant une ou plusieurs fois par jour. The cosmetic compositions of the present invention are preferably to be used daily by applying them one or more times a day.
Les compositions cosmétiques de la présente invention sont très bien tolérées, elles ne présentent aucune phototoxicité et leur application sur la peau, pour des périodes de temps prolongées, n'implique aucun effet systématique. The cosmetic compositions of the present invention are very well tolerated, they have no phototoxicity and their application to the skin, for prolonged periods of time, does not imply any systematic effect.
Claims (10)
Priority Applications (1)
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FR9702279A FR2759910B1 (en) | 1997-02-24 | 1997-02-24 | COSMETIC OR DERMOPHARMACEUTICAL COMPOSITIONS FOR STRENGTHENING THE BUST, STIMULATING THE HAIR SYSTEM AND INHIBITION OR HAIRY SYSTEM, CONTAINING KIGELIA AFRICANA EXTRACTS |
Applications Claiming Priority (1)
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FR9702279A FR2759910B1 (en) | 1997-02-24 | 1997-02-24 | COSMETIC OR DERMOPHARMACEUTICAL COMPOSITIONS FOR STRENGTHENING THE BUST, STIMULATING THE HAIR SYSTEM AND INHIBITION OR HAIRY SYSTEM, CONTAINING KIGELIA AFRICANA EXTRACTS |
Publications (2)
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FR2759910A1 true FR2759910A1 (en) | 1998-08-28 |
FR2759910B1 FR2759910B1 (en) | 1999-12-03 |
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FR9702279A Expired - Lifetime FR2759910B1 (en) | 1997-02-24 | 1997-02-24 | COSMETIC OR DERMOPHARMACEUTICAL COMPOSITIONS FOR STRENGTHENING THE BUST, STIMULATING THE HAIR SYSTEM AND INHIBITION OR HAIRY SYSTEM, CONTAINING KIGELIA AFRICANA EXTRACTS |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2780885A1 (en) * | 1998-07-10 | 2000-01-14 | C3D Sarl | NEW HIGH VISCOSITY COSMETIC COMPOSITIONS FOR APPLICATION ON THE SKIN |
WO2006002443A1 (en) * | 2004-06-24 | 2006-01-05 | Rudolf Karl Schleipfer | Pharmaceutical or cosmetic preparation based on kigelia africana |
WO2014015881A2 (en) | 2012-07-25 | 2014-01-30 | Kimovi Aps | A cosmetic or medical composition with kigelia africana |
US20140301960A1 (en) * | 2012-11-14 | 2014-10-09 | Coty Germany Gmbh | Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles |
WO2015028035A1 (en) * | 2013-09-02 | 2015-03-05 | Unigroup Aps | Dermatological composition |
FR3104033A1 (en) * | 2019-12-09 | 2021-06-11 | L V M H Recherche | Cosmetic composition comprising extracts of kigelia and orchid |
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Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2780885A1 (en) * | 1998-07-10 | 2000-01-14 | C3D Sarl | NEW HIGH VISCOSITY COSMETIC COMPOSITIONS FOR APPLICATION ON THE SKIN |
WO2000002531A1 (en) * | 1998-07-10 | 2000-01-20 | C3D S.A.R.L. | Novel high viscosity cosmetic compositions to be applied on the skin |
WO2006002443A1 (en) * | 2004-06-24 | 2006-01-05 | Rudolf Karl Schleipfer | Pharmaceutical or cosmetic preparation based on kigelia africana |
WO2014015881A2 (en) | 2012-07-25 | 2014-01-30 | Kimovi Aps | A cosmetic or medical composition with kigelia africana |
US20140301960A1 (en) * | 2012-11-14 | 2014-10-09 | Coty Germany Gmbh | Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles |
US9149659B2 (en) * | 2012-11-14 | 2015-10-06 | Coty Germany Gmbh | Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles |
WO2015028035A1 (en) * | 2013-09-02 | 2015-03-05 | Unigroup Aps | Dermatological composition |
FR3104033A1 (en) * | 2019-12-09 | 2021-06-11 | L V M H Recherche | Cosmetic composition comprising extracts of kigelia and orchid |
WO2021116573A1 (en) * | 2019-12-09 | 2021-06-17 | L V M H Recherche | Cosmetic composition comprising extracts of kigelia and orchid |
Also Published As
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FR2759910B1 (en) | 1999-12-03 |
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