FR2742155B1 - Utilisation de derives heteroaromatiques et tricycliques du 1,4-dihydro-1,4-dioxonaphtalene, nouveaux composes obtenus et leur application en therapeutique - Google Patents

Utilisation de derives heteroaromatiques et tricycliques du 1,4-dihydro-1,4-dioxonaphtalene, nouveaux composes obtenus et leur application en therapeutique

Info

Publication number
FR2742155B1
FR2742155B1 FR9514685A FR9514685A FR2742155B1 FR 2742155 B1 FR2742155 B1 FR 2742155B1 FR 9514685 A FR9514685 A FR 9514685A FR 9514685 A FR9514685 A FR 9514685A FR 2742155 B1 FR2742155 B1 FR 2742155B1
Authority
FR
France
Prior art keywords
dioxonaphtalene
heteroaromatic
therapeutics
dihydro
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9514685A
Other languages
English (en)
Other versions
FR2742155A1 (fr
Inventor
Falson Odile Boutherin
Billiald Stephanie Desquand
Anita Favrou
Michel Finet
Norbert Olivier Tembo
Jean Luc Torregrosa
Arnoult Sylvie Yannic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Innothera SAS
Original Assignee
Laboratoires Innothera SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Innothera SAS filed Critical Laboratoires Innothera SAS
Priority to FR9514685A priority Critical patent/FR2742155B1/fr
Priority to EP96941736A priority patent/EP0874844A1/fr
Priority to PCT/FR1996/001975 priority patent/WO1997021710A1/fr
Priority to JP09521801A priority patent/JP2000502081A/ja
Publication of FR2742155A1 publication Critical patent/FR2742155A1/fr
Application granted granted Critical
Publication of FR2742155B1 publication Critical patent/FR2742155B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR9514685A 1995-12-12 1995-12-12 Utilisation de derives heteroaromatiques et tricycliques du 1,4-dihydro-1,4-dioxonaphtalene, nouveaux composes obtenus et leur application en therapeutique Expired - Fee Related FR2742155B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR9514685A FR2742155B1 (fr) 1995-12-12 1995-12-12 Utilisation de derives heteroaromatiques et tricycliques du 1,4-dihydro-1,4-dioxonaphtalene, nouveaux composes obtenus et leur application en therapeutique
EP96941736A EP0874844A1 (fr) 1995-12-12 1996-12-10 Utilisation de derives heteroaromatiques et tricycliques du 1,4-dihydro-1,4-dioxo-naphtalene, nouveaux composes obtenus et leur application en therapeutique
PCT/FR1996/001975 WO1997021710A1 (fr) 1995-12-12 1996-12-10 Utilisation de derives heteroaromatiques et tricycliques du 1,4-dihydro-1,4-dioxo-naphtalene, nouveaux composes obtenus et leur application en therapeutique
JP09521801A JP2000502081A (ja) 1995-12-12 1996-12-10 １，４―ジヒドロ―１，４―ジオキソナフタレンのヘテロ芳香族及び三環式誘導体の利用、得られる新規化合物並びにその治療用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9514685A FR2742155B1 (fr) 1995-12-12 1995-12-12 Utilisation de derives heteroaromatiques et tricycliques du 1,4-dihydro-1,4-dioxonaphtalene, nouveaux composes obtenus et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2742155A1 FR2742155A1 (fr) 1997-06-13
FR2742155B1 true FR2742155B1 (fr) 1998-02-13

Family

ID=9485395

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9514685A Expired - Fee Related FR2742155B1 (fr) 1995-12-12 1995-12-12 Utilisation de derives heteroaromatiques et tricycliques du 1,4-dihydro-1,4-dioxonaphtalene, nouveaux composes obtenus et leur application en therapeutique

Country Status (4)

Country Link
EP (1) EP0874844A1 (fr)
JP (1) JP2000502081A (fr)
FR (1) FR2742155B1 (fr)
WO (1) WO1997021710A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003999A (en) * 1997-12-19 1999-07-12 Advanced Research And Technology Institute, Inc. Modulators of ryanodine receptors comprising 2-(aryl)-4,7-dioxobenzothiazoles and analogues thereof
EP1637134A4 (fr) * 2003-06-20 2010-01-27 Mochida Pharm Co Ltd Composition pour la prevention et le traitement des varices
WO2007149484A2 (fr) 2006-06-20 2007-12-27 Dana-Farber Cancer Institute Inhibiteurs de complexe enzymatique provoquant la désubiquitination du usp1
CA2797719C (fr) 2010-04-30 2019-11-26 Dana-Farber Cancer Institute, Inc. Inhibiteurs de petites molecules de l'activite de l'enzyme de deubiquination usp1
US9725425B1 (en) 2014-02-25 2017-08-08 Dana-Farber Cancer Institute, Inc. Compounds and methods for treating cancer
CN115286594B (zh) * 2022-07-24 2023-07-25 浙江工业大学 一种以s8为原料合成醌并噻唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05112533A (ja) * 1991-05-08 1993-05-07 Upjohn Co:The イミダゾベンゾキノン類およびこれを有効成分とする高血圧・鬱血性心不全の予防・治療剤

Also Published As

Publication number Publication date
EP0874844A1 (fr) 1998-11-04
FR2742155A1 (fr) 1997-06-13
WO1997021710A1 (fr) 1997-06-19
JP2000502081A (ja) 2000-02-22

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Legal Events

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ST Notification of lapse