FR2737106A1 - Fibrillar sheet of biocompatible polymer opt. impregnated with medical elastomer of plastomer, with one rough surface - and use for reconstitution in surgery, esp,close to brain or spinal marrow, avoiding risk of infection in using tissue from cadaver - Google Patents

Fibrillar sheet of biocompatible polymer opt. impregnated with medical elastomer of plastomer, with one rough surface - and use for reconstitution in surgery, esp,close to brain or spinal marrow, avoiding risk of infection in using tissue from cadaver Download PDF

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Publication number
FR2737106A1
FR2737106A1 FR9509380A FR9509380A FR2737106A1 FR 2737106 A1 FR2737106 A1 FR 2737106A1 FR 9509380 A FR9509380 A FR 9509380A FR 9509380 A FR9509380 A FR 9509380A FR 2737106 A1 FR2737106 A1 FR 2737106A1
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France
Prior art keywords
reconstitution
plate according
fibrillar
impregnated
rough surface
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Granted
Application number
FR9509380A
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French (fr)
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FR2737106B1 (en
Inventor
Jean Frismand
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Cousin Biotech SAS
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Cousin Biotech SAS
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Priority to FR9509380A priority Critical patent/FR2737106B1/en
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Publication of FR2737106B1 publication Critical patent/FR2737106B1/en
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Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0063Implantable repair or support meshes, e.g. hernia meshes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42Gynaecological or obstetrical instruments or methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/10Hair or skin implants
    • A61F2/105Skin implants, e.g. artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

A sheet with a fibrillar structure has a rough surface, close to the natural conjunctive structure, and is so formed of a bio-compatible polymer, and may be impregnated with a very small amt. of a medical elastomer or plastomer.

Description

L'invention concerne une plaque de reconstitution pour le domaine de la chirurgie. The invention relates to a reconstruction plate for the field of surgery.

Dans les interventions chirurgicales touchant ou approchant le cerveau ou la moelle épinière, il faut protéger ou reconstituer les enveloppes de ces tissus dits nobles et, en particulier, la membrane extérieure appelée dure-mère contre la fibrose cicatricielle post clururgicale. Dans ce but, il est habituel d'utiliser un morceau de dure-mère prélevé sur cadavre, traité et stérilisé, placé au contact direct des tissus nobles par le chirurgien.Hors ce matériau présente plusieurs inconvénients : il est coûteux du fait de sa provenance humaine et des traitements nécessaires, et surtout peut transmettre des maladies (sida, hépatite, Creutzfeldt-jakob...). Ces maladies ne sont pas forcément détectables par les tests de laboratoire : il existe des périodes de latence pendant lesquelles les porteurs de ces maladies sont déjà contagieux, c'est dire peuvent transmettre la maladie, et où les tests de laboratoire ne sont pas encore positifs. In surgical procedures touching or approaching the brain or the spinal cord, it is necessary to protect or reconstitute the envelopes of these so-called noble tissues and, in particular, the outer membrane called dura mater against postclururgical scar fibrosis. For this purpose, it is usual to use a piece of dura mater taken from a corpse, treated and sterilized, placed in direct contact with the noble tissues by the surgeon. However, this material has several disadvantages: it is expensive because of its origin human and necessary treatments, and above all can transmit diseases (AIDS, hepatitis, Creutzfeldt-jakob ...). These diseases are not necessarily detectable by laboratory tests: there are latency periods during which the carriers of these diseases are already contagious, that is to say can transmit the disease, and where laboratory tests are not yet positive .

L'invention a pour objet d'éviter ces risques de transmission de maladies par les tissus d'origine humaine ou animale, en réalisant une plaque présentant une structure fibrillaire proche de la structure conjonctive naturelle, fabriquée en matériau synthétique, donc exempte de maladie afin de protéger les tissus nobles contre la fibrose cicatricielle. The object of the invention is to avoid these risks of transmission of diseases by tissues of human or animal origin, by producing a plate having a fibrillar structure close to the natural connective structure, made of synthetic material, therefore free of disease so protect noble tissue against scar fibrosis.

L'invention consiste à utiliser un tissu textile poreux de construction serrée, que l'on peut imprégner d'une très faible quantité d'un élastomère médical afin de rendre les fils du tissu plus lisses, moins perméables et non traumatisants pour les tissus mais aptes à laisser passer les fluides biologiques. The invention consists in using a porous textile fabric of tight construction, which can be impregnated with a very small amount of a medical elastomer in order to make the threads of the fabric smoother, less permeable and non-traumatic for the tissues but suitable for letting biological fluids through.

On peut d'ailleurs améliorer l'aspect lisse en réalisant sur une face du produit un côté totalement lisse par dépôt d'une couche uniforme d'élastomère et en laissant l'autre côté plus rugueux pour permettre sa réhabitation par les tissus de l'hôte. Le côté lisse sera placé en regard des tissus nobles et le côté rugueux en regard des tissus conjonctifs ou musculaires pour permettre la réhabitation tissulaire. We can also improve the smooth appearance by making a completely smooth side on one side of the product by depositing a uniform layer of elastomer and leaving the other side rougher to allow it to be re-used by the tissues of the host. The smooth side will be placed opposite the noble tissues and the rough side opposite the connective or muscular tissues to allow tissue rehabitation.

Le tissu textile peut être un tricot, un tissu serré, ou de façon plus satisfaisante, un produit dit non tissé réalisé en enchevêtrant des fils par technique de jet d'air, par exemple, ou par soudure fil à fil. Ces produits présentent l'avantage d'une structure fibrillaire proche de la structure conjonctive naturelle. The textile fabric can be a knitted fabric, a tight fabric, or more satisfactorily, a so-called non-woven product produced by entangling threads by air jet technique, for example, or by thread-to-thread welding. These products have the advantage of a fibrillar structure close to the natural connective structure.

A titre d'exemple de réalisation d'une plaque selon l'invention, on utilise un produit non tissé 100% polyester. Ce produit, après nettoyage par les techniques connues, est imprégné avec une silicone de grade médical par trempage puis égouttage et polymérisation à l'étuve. As an exemplary embodiment of a plate according to the invention, a 100% polyester nonwoven product is used. This product, after cleaning by known techniques, is impregnated with a medical grade silicone by soaking then draining and polymerization in an oven.

La plaque obtenue est légèrement perméable du fait de la faible quantité de silicone, très souple et pouvant se déformer facilement pour les mêmes raisons; elle permet le passage des fluides biologiques. The plate obtained is slightly permeable due to the small amount of silicone, very flexible and which can easily deform for the same reasons; it allows the passage of biological fluids.

Selon un mode préférentiel de réalisation de l'invention, on a déposé 8mg/cm2 d'élastomère sur un non tissé de 0,45 mm d'épaisseur pesant 8mg/cm2. According to a preferred embodiment of the invention, 8 mg / cm 2 of elastomer has been deposited on a 0.45 mm thick nonwoven weighing 8 mg / cm 2.

Si on désire obtenir une face parfaitement lisse, on réalise, avant polymérisation, le dépôt par calandrage d'une fine couche de silicone sur une face du produit, l'ensemble étant ensuite polymérisé à l'étuve. A partir d'un non tissé de 0,45 mm d'épaisseur initiale, on obtient après imprégnation et calandrage d'une couche de silicone sur une face un produit final de 0,60 mm d'épaisseur environ. If it is desired to obtain a perfectly smooth face, before coating, polymerization is carried out by calendering a thin layer of silicone on one side of the product, the assembly then being polymerized in an oven. From a non-woven fabric with an initial thickness of 0.45 mm, a final product with a thickness of approximately 0.60 mm is obtained after impregnation and calendering of a layer of silicone on one side.

L'exemple de réalisation avec un non tissé peut, bien entendu, être étendu à tout type de construction textile, tricot de tout type, tissu, voire tresse plate. Les épaisseurs et masse des tissus, les quantités déposées peuvent varier en fonction des tissus et des applications. The exemplary embodiment with a nonwoven can, of course, be extended to any type of textile construction, knitting of any type, fabric, or even flat braid. The thicknesses and mass of the fabrics, the quantities deposited can vary depending on the fabrics and applications.

Le matériau du tissu ayant une structure fibrillaire proche de la structure conjonctive naturelle est un polymère biocompatible qui peut être du polyester, du polyamide, du polypropylène, du polytétrafluoroéthylène ou tout matériau biocompatible, très souple et non traumatisant pour les tissus. The material of the tissue having a fibrillar structure close to the natural connective structure is a biocompatible polymer which can be polyester, polyamide, polypropylene, polytetrafluoroethylene or any biocompatible material, very flexible and non-traumatic for the tissues.

L'élastomère biocompatible utilisé peut être de la silicone, du polyuréthanne ou tout autre élastomère biocompatible résorbable ou non résorbable. The biocompatible elastomer used can be silicone, polyurethane or any other absorbable or non-absorbable biocompatible elastomer.

Un plastomère peut également être utilisé pour imprégner le tissu et particulièrement le polyamide, polychlorure de vinyle, polyester, polyuréthanne ou polyoléfine. A plastomer can also be used to impregnate the fabric and in particular polyamide, polyvinyl chloride, polyester, polyurethane or polyolefin.

L'application décrit une plaque pour les traitements de neurochirurgie touchant ou approchant la dure mère, mais l'invention permet de réaliser des plaques pour d'autres interventions : plaques de renfort pour la chirurgie orthopédique, chirurgie viscérale, dont le traitement des hernies, chirurgie gynécologique, chirurgie cardiaque et vasculaire et de façon générale toutes les applications médicales et vétérinaires bénéficiant de plaques à structure fibrillaire proche de la structure conjonctive naturelle, imprégnées d'une très faible quantité d'un élastomère médical afin de rendre les fils du tissu plus lisses, moins perméables et non traumatisants pour les tissus. The application describes a plate for neurosurgical treatments touching or approaching the dura mater, but the invention makes it possible to produce plates for other interventions: reinforcement plates for orthopedic surgery, visceral surgery, including the treatment of hernias, gynecological surgery, cardiac and vascular surgery and in general all medical and veterinary applications benefiting from plates with fibrillar structure close to the natural connective structure, impregnated with a very small amount of a medical elastomer in order to make the threads of the tissue more smooth, less permeable and non-traumatic for the tissues.

Selon un autre mode de réalisation de l'invention, on imprègne un produit textile tubulaire afin d'obtenir une prothèse vasculaire souple et élastique, mais gardant sa forme tubulaire et légèrement perméable pour laisser passer les fluides biologiques.  According to another embodiment of the invention, a tubular textile product is impregnated in order to obtain a flexible and elastic vascular prosthesis, but retaining its tubular shape and slightly permeable to let the biological fluids pass.

Claims (10)

REVENDICATIONS 1. plaque de reconstitution pour les traitements de chirurgie caractérisée en ce qu'elle présente une structure fibrillaire, comportant au moins une face à surface rugueuse, proche de la structure conjonctive naturelle, réalisée avec un polymère biocompatible et qu'elle peut être imprégnée d'une très faible quantité d'un élastomère ou plastomère médical. 1. reconstitution plate for surgical treatments, characterized in that it has a fibrillar structure, comprising at least one face with a rough surface, close to the natural connective structure, produced with a biocompatible polymer and that it can be impregnated with '' a very small amount of a medical elastomer or plastomer. 2. plaque de reconstitution selon la revendication 1 caractérisée en ce que la structure fibrillaire comporte une face avec une surface rugueuse qui permet la réhabitation tissulaire et une face lisse apte à coopérer avec les tissus nobles. 2. reconstitution plate according to claim 1 characterized in that the fibrillar structure comprises a face with a rough surface which allows tissue rehabitation and a smooth face capable of cooperating with the noble tissues. 3. plaque de reconstitution selon la revendication 1 caractérisée en ce que la structure fibrillaire est réalisée avec une construction textile poreuse. 3. reconstitution plate according to claim 1 characterized in that the fibrillar structure is produced with a porous textile construction. 4. plaque de reconstitution selon la revendication 1 caractérisée en ce que la structure fibrillaire est réalisée avec un produit textile et particulièrement un non tissé, un tricot de tout type, un tissu, voire une tresse plate. 4. reconstruction plate according to claim 1 characterized in that the fibrillar structure is made with a textile product and particularly a nonwoven, a knitted fabric of any type, a fabric, or even a flat braid. 5. plaque de reconstitution selon la revendication 1 caractérisée en ce que le polymère biocompatible de la structure fibrillaire peut être notamment du polyester, du polyamide, du polypropylène, ou du polytétrafluoroéthylène. 5. reconstitution plate according to claim 1 characterized in that the biocompatible polymer of the fibrillar structure can be in particular polyester, polyamide, polypropylene, or polytetrafluoroethylene. 6. plaque de reconstitution selon la revendication 1 caractérisée en ce que l'élastomère biocompatible peut être notamment de la silicone ou du polyuréthanne. 6. reconstitution plate according to claim 1 characterized in that the biocompatible elastomer can be in particular silicone or polyurethane. 7. plaque de reconstitution selon la revendication 1 caractérisée en ce que le plastomère peut être notamment du polyamide, du polychlorure de vinyle, du polyester, du polyuréthanne ou une polyoléfine. 7. reconstitution plate according to claim 1 characterized in that the plastomer can be in particular polyamide, polyvinyl chloride, polyester, polyurethane or a polyolefin. 8. plaque de reconstitution selon la revendication 3 caractérisée en ce que la structure textile poreuse est apte à laisser passer les fluides biologiques. 8. reconstitution plate according to claim 3 characterized in that the porous textile structure is capable of letting biological fluids pass. 9. procédé pour préparer une plaque selon la revendication 1 caractérisée en ce que la structure fibrillaire est nettoyée puis imprégnée par trempage, puis égouttée, puis polymérisée à l'étuve. Cette structure fibrillaire est réalisée à partir d'un non tissé qui peut être a titre d'exemple de 0,45 mm d'épaisseur initiale et peser 8mg/cm2 sur lequel on déposera par exemple 8mg/cm2 d'élastomère. 9. Process for preparing a plate according to claim 1 characterized in that the fibrillar structure is cleaned then impregnated by soaking, then drained, then polymerized in an oven. This fibrillar structure is produced from a nonwoven which can be, for example, 0.45 mm in initial thickness and weigh 8 mg / cm 2 onto which, for example, 8 mg / cm 2 of elastomer will be deposited. 10. procédé pour préparer une plaque selon les revendications 1 et 2 caractérisée en ce que la face à surface rugueuse est réalisée par nettoyage, imprégnation par trempage, puis égouttage d'un tissu et que la surface lisse est réalisée par calandrage, l'ensemble étant ensuite polymérisé à l'étuve. A partir d'un non tissé qui peut être a titre d'exemple de 0,45 mm d'épaisseur initiale, on opère l'imprégnation et le calandrage d'une couche de silicone sur une face du produit qui peut donner à titre d'exemple un produit final de 0,60 mm d'épaisseur environ.  10. process for preparing a plate according to claims 1 and 2 characterized in that the surface with a rough surface is produced by cleaning, impregnation by dipping, then draining of a fabric and that the smooth surface is produced by calendering, the assembly then being polymerized in an oven. Starting from a nonwoven which can be, for example, 0.45 mm in initial thickness, the impregnation and calendering of a layer of silicone is carried out on one side of the product which can give, as a 'example a final product about 0.60 mm thick.
FR9509380A 1995-07-27 1995-07-27 RECONSTRUCTION PLATE WITH FIBRILLARY STRUCTURE, FLEXIBLE AND WITH MEMORY, FOR THE FIELD OF VISCERAL SURGERY Expired - Fee Related FR2737106B1 (en)

Priority Applications (1)

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FR9509380A FR2737106B1 (en) 1995-07-27 1995-07-27 RECONSTRUCTION PLATE WITH FIBRILLARY STRUCTURE, FLEXIBLE AND WITH MEMORY, FOR THE FIELD OF VISCERAL SURGERY

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FR9509380A FR2737106B1 (en) 1995-07-27 1995-07-27 RECONSTRUCTION PLATE WITH FIBRILLARY STRUCTURE, FLEXIBLE AND WITH MEMORY, FOR THE FIELD OF VISCERAL SURGERY

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FR2737106A1 true FR2737106A1 (en) 1997-01-31
FR2737106B1 FR2737106B1 (en) 1997-10-03

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998058598A1 (en) * 1997-06-21 1998-12-30 Hans Haindl Bag for at least partially enveloping a heart
FR2776179A1 (en) * 1998-03-20 1999-09-24 Cousin Biotech SURGICAL PLATE
ES2137100A1 (en) * 1997-01-29 1999-12-01 Cousin Biotech S A R L Surgical plate.
WO2001080774A1 (en) * 2000-04-26 2001-11-01 Aspide Reinforcing wall for treating damaged abdominal wall tissues
EP1192958A2 (en) * 2000-08-28 2002-04-03 Axel Bernard Multilayer textile product for surgical covering and clothing
WO2002019945A3 (en) * 2000-09-07 2002-05-10 American Med Syst Coated sling material
US6592515B2 (en) 2000-09-07 2003-07-15 Ams Research Corporation Implantable article and method
FR2864443A1 (en) 2003-12-24 2005-07-01 Cousin Biotech Surgical textile implant for treating e.g. hernia, has zones marked with hackings to distinguish anatomical parts of human organism from prohibited zones, and centering mark marked on organism by crosses using biocompatible ink

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FR2281448A1 (en) * 1974-08-05 1976-03-05 Ici Ltd FIBROUS PRODUCT, ESPECIALLY FOR DRESSINGS AND PROSTHESIS COATINGS, AND ITS PRODUCTION PROCESS
GB2033234A (en) * 1978-10-12 1980-05-21 Sumitomo Electric Industries Tubular organic prosthesis and a process for the production thereof
WO1990014810A1 (en) * 1989-05-26 1990-12-13 Ramon Berguer Blood vessel patch
GB2247696A (en) * 1990-08-28 1992-03-11 Meadox Medicals Inc Woven synthetic vascular graft
WO1994019029A1 (en) * 1993-02-18 1994-09-01 W.L. Gore & Associates, Inc. A laminated patch tissue repair sheet material

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DE2065440A1 (en) * 1970-05-08 1973-07-19 Charles Howard Sparks Graft reinforcement - for encapsulation with living - tissues is silicone rubber impregnated material
FR2281448A1 (en) * 1974-08-05 1976-03-05 Ici Ltd FIBROUS PRODUCT, ESPECIALLY FOR DRESSINGS AND PROSTHESIS COATINGS, AND ITS PRODUCTION PROCESS
GB2033234A (en) * 1978-10-12 1980-05-21 Sumitomo Electric Industries Tubular organic prosthesis and a process for the production thereof
WO1990014810A1 (en) * 1989-05-26 1990-12-13 Ramon Berguer Blood vessel patch
GB2247696A (en) * 1990-08-28 1992-03-11 Meadox Medicals Inc Woven synthetic vascular graft
WO1994019029A1 (en) * 1993-02-18 1994-09-01 W.L. Gore & Associates, Inc. A laminated patch tissue repair sheet material

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2137100A1 (en) * 1997-01-29 1999-12-01 Cousin Biotech S A R L Surgical plate.
WO1998058598A1 (en) * 1997-06-21 1998-12-30 Hans Haindl Bag for at least partially enveloping a heart
US6645139B2 (en) 1997-06-21 2003-11-11 Acorn Cardiovascular Inc. Bag for at least partially enveloping a heart
US6416459B1 (en) 1997-06-21 2002-07-09 Acorn Cardiovascular Inc. Bag for at least partially enveloping a heart
FR2776179A1 (en) * 1998-03-20 1999-09-24 Cousin Biotech SURGICAL PLATE
EP0943298A3 (en) * 1998-03-20 2003-03-12 Cousin Biotech (S.A.S.) Surgical patch
WO2001080774A1 (en) * 2000-04-26 2001-11-01 Aspide Reinforcing wall for treating damaged abdominal wall tissues
FR2808185A1 (en) * 2000-04-26 2001-11-02 Aspide REINFORCING WALL FOR THE TREATMENT OF ALTERNATIVE FABRICS OF THE ABDOMINAL WALL
EP1192958A2 (en) * 2000-08-28 2002-04-03 Axel Bernard Multilayer textile product for surgical covering and clothing
EP1192958A3 (en) * 2000-08-28 2002-04-17 Axel Bernard Multilayer textile product for surgical covering and clothing
US6592515B2 (en) 2000-09-07 2003-07-15 Ams Research Corporation Implantable article and method
WO2002019945A3 (en) * 2000-09-07 2002-05-10 American Med Syst Coated sling material
US6884212B2 (en) 2000-09-07 2005-04-26 Ams Research Corporation Implantable article and method
US7025063B2 (en) 2000-09-07 2006-04-11 Ams Research Corporation Coated sling material
US7517313B2 (en) 2000-09-07 2009-04-14 Ams Research Corporation Implantable article and method
US8147478B2 (en) 2000-09-07 2012-04-03 Ams Research Corporation Coated sling material
US8702586B2 (en) 2000-09-07 2014-04-22 Ams Research Corporation Implantable article and method
US8905912B2 (en) 2000-09-07 2014-12-09 Ams Research Corporation Implantable article and method
US9022921B2 (en) 2000-09-07 2015-05-05 Ams Research Corporation Implantable article and method
US9211177B2 (en) 2000-09-07 2015-12-15 Ams Research Corporation Implantable article and method
US9987113B2 (en) 2000-09-07 2018-06-05 Astora Women's Health, Llc Implantable article and method
FR2864443A1 (en) 2003-12-24 2005-07-01 Cousin Biotech Surgical textile implant for treating e.g. hernia, has zones marked with hackings to distinguish anatomical parts of human organism from prohibited zones, and centering mark marked on organism by crosses using biocompatible ink

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