FR2729952B1 - SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
FR2729952B1
FR2729952B1 FR9501016A FR9501016A FR2729952B1 FR 2729952 B1 FR2729952 B1 FR 2729952B1 FR 9501016 A FR9501016 A FR 9501016A FR 9501016 A FR9501016 A FR 9501016A FR 2729952 B1 FR2729952 B1 FR 2729952B1
Authority
FR
France
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
substituted heterocyclic
heterocyclic compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9501016A
Other languages
French (fr)
Other versions
FR2729952A1 (en
Inventor
Alt Xavier Emonds
Isabelle Grossriether
Patrick Gueule
Vincenzo Proietto
Didier Van Broeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR9501016A priority Critical patent/FR2729952B1/en
Priority to FR9508046A priority patent/FR2729953B1/en
Priority to FR9513005A priority patent/FR2729954B1/en
Priority to MYPI96000294A priority patent/MY117527A/en
Priority to TW085101094A priority patent/TW345582B/en
Priority to ARP960101182A priority patent/AR002955A1/en
Priority to CZ19972436A priority patent/CZ293134B6/en
Priority to ZA96694A priority patent/ZA96694B/en
Priority to EP06005775A priority patent/EP1688416A1/en
Priority to EP03012771A priority patent/EP1340754A1/en
Priority to MX9705590A priority patent/MX9705590A/en
Priority to HU9800295A priority patent/HUP9800295A3/en
Priority to CNB2004100929315A priority patent/CN1295221C/en
Priority to CA002211668A priority patent/CA2211668C/en
Priority to DE69622992T priority patent/DE69622992T2/en
Priority to AU46669/96A priority patent/AU707901B2/en
Priority to KR1019970705205A priority patent/KR19980701808A/en
Priority to SI9630532T priority patent/SI0807111T1/en
Priority to JP52330896A priority patent/JP3234228B2/en
Priority to PCT/FR1996/000152 priority patent/WO1996023787A1/en
Priority to DK01119949T priority patent/DK1156049T3/en
Priority to EP07150446A priority patent/EP1923391A1/en
Priority to US08/593,938 priority patent/US5641777A/en
Priority to IL11695796A priority patent/IL116957A/en
Priority to DE69634806T priority patent/DE69634806T2/en
Priority to CNA2007103059153A priority patent/CN101230008A/en
Priority to EP01119949A priority patent/EP1156049B1/en
Priority to CNA2006100088681A priority patent/CN1821241A/en
Priority to IL11605796A priority patent/IL116957A0/en
Priority to CN96191686A priority patent/CN1089764C/en
Priority to ES01119949T priority patent/ES2243373T3/en
Priority to PT01119949T priority patent/PT1156049E/en
Priority to KR10-2003-7012641A priority patent/KR100477164B1/en
Priority to DK96902305T priority patent/DK0807111T3/en
Priority to CNB200310119883XA priority patent/CN1293063C/en
Priority to ES96902305T priority patent/ES2181866T3/en
Priority to AT01119949T priority patent/ATE296823T1/en
Priority to CZ20022243A priority patent/CZ294267B6/en
Priority to KR10-2004-7005797A priority patent/KR100509220B1/en
Priority to PT96902305T priority patent/PT807111E/en
Priority to EP96902305A priority patent/EP0807111B1/en
Priority to SI9630713T priority patent/SI1156049T1/en
Priority to RU97114938/04A priority patent/RU2157807C2/en
Priority to PL321640A priority patent/PL192164B1/en
Priority to IL12711496A priority patent/IL127114A/en
Priority to AT96902305T priority patent/ATE222251T1/en
Priority to NZ301285A priority patent/NZ301285A/en
Publication of FR2729952A1 publication Critical patent/FR2729952A1/en
Priority to US08/703,729 priority patent/US5780466A/en
Priority to US08/820,716 priority patent/US5869663A/en
Application granted granted Critical
Publication of FR2729952B1 publication Critical patent/FR2729952B1/en
Priority to BR1100937-3A priority patent/BR1100937A/en
Priority to NO973479A priority patent/NO308795B1/en
Priority to FI973148A priority patent/FI973148A/en
Priority to US09/004,454 priority patent/US6011154A/en
Priority to HK02103621.9A priority patent/HK1041881B/en
Priority to US09/175,331 priority patent/US6242637B1/en
Priority to US09/175,332 priority patent/US5977359A/en
Priority to IL12711498A priority patent/IL127114A0/en
Priority to JP2000342571A priority patent/JP3357660B2/en
Priority to JP2000342606A priority patent/JP2001131171A/en
Priority to CNB011163402A priority patent/CN1136189C/en
Priority to CNB011163410A priority patent/CN1179954C/en
Priority to JP2001339406A priority patent/JP3943369B2/en
Priority to CNB011431032A priority patent/CN1202093C/en
Priority to ARP020101908A priority patent/AR036027A2/en
Priority to CY0300053A priority patent/CY2369B1/en
Priority to CY0500044A priority patent/CY2537B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C219/22—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/36—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
    • C07C255/43—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
FR9501016A 1995-01-30 1995-01-30 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Expired - Fee Related FR2729952B1 (en)

Priority Applications (66)

Application Number Priority Date Filing Date Title
FR9501016A FR2729952B1 (en) 1995-01-30 1995-01-30 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR9508046A FR2729953B1 (en) 1995-01-30 1995-07-04 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR9513005A FR2729954B1 (en) 1995-01-30 1995-11-03 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
MYPI96000294A MY117527A (en) 1995-01-30 1996-01-26 Substituted heterocyclic compounds, method of preparing them and pharmaceutical compositions in which they are present
TW085101094A TW345582B (en) 1995-01-30 1996-01-29 Substituted heterocyclic compounds, method of preparing them and pharmaceutical compositions in which they are present
ARP960101182A AR002955A1 (en) 1995-01-30 1996-01-29 A SUBSTITUTED HETERO-CYCLIC COMPOUND, PROCEDURE AND INTERMEDIARY COMPOUNDS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING SUCH COMPOUND.
CZ19972436A CZ293134B6 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method and intermediates therefor and pharmaceutical composition containing such compounds
ZA96694A ZA96694B (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present
EP06005775A EP1688416A1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, their process of preparation and pharmaceutical compositions containing them
EP03012771A EP1340754A1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
MX9705590A MX9705590A (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same.
HU9800295A HUP9800295A3 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same, intermediates of them
CNB2004100929315A CN1295221C (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds
CA002211668A CA2211668C (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing the same
DE69622992T DE69622992T2 (en) 1995-01-30 1996-01-30 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
AU46669/96A AU707901B2 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, method of preparing them and pharmaceutical compositions in which they are present
KR1019970705205A KR19980701808A (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, methods for their preparation and pharmaceutical compositions containing them
SI9630532T SI0807111T1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same
JP52330896A JP3234228B2 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compound and method for producing the same
PCT/FR1996/000152 WO1996023787A1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same
DK01119949T DK1156049T3 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, processes for their preparation and pharmaceutical compositions containing them
EP07150446A EP1923391A1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, method for preparing same and pharmaceutical compositions containing them.
US08/593,938 US5641777A (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds and pharmaceutical compositions in which they are present
IL11695796A IL116957A (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds their preparation and pharmaceutical compositions containing them
DE69634806T DE69634806T2 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
CNA2007103059153A CN101230008A (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
EP01119949A EP1156049B1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, their process of preparation and pharmaceutical compositions containing them
CNA2006100088681A CN1821241A (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same
IL11605796A IL116957A0 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds their preparation and pharmaceutical compositions containing them
CN96191686A CN1089764C (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method thereof and pharmaceutical compositions containing same
ES01119949T ES2243373T3 (en) 1995-01-30 1996-01-30 SUBSTITUTED HETEROCICLIC COMPOUNDS, PROCEDURE FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
PT01119949T PT1156049E (en) 1995-01-30 1996-01-30 SUBSTITUTED HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
KR10-2003-7012641A KR100477164B1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method thereof and pharmaceutical compositions containing same
DK96902305T DK0807111T3 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, processes for their preparation and pharmaceutical compositions containing them
CNB200310119883XA CN1293063C (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
ES96902305T ES2181866T3 (en) 1995-01-30 1996-01-30 SUBSTITUTED HETEROCICLIC COMPOUNDS, PROCEDURE FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
AT01119949T ATE296823T1 (en) 1995-01-30 1996-01-30 SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
CZ20022243A CZ294267B6 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds
KR10-2004-7005797A KR100509220B1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method thereof and pharmaceutical compositions containing same
PT96902305T PT807111E (en) 1995-01-30 1996-01-30 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EP96902305A EP0807111B1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same
SI9630713T SI1156049T1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, their process of preparation and pharmaceutical compositions containing them
RU97114938/04A RU2157807C2 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, method of their synthesis and pharmaceutical composition
PL321640A PL192164B1 (en) 1995-01-30 1996-01-30 Substituted heterocyclic compounds, method of obtaining them and pharmaceutic compositions containing such compounds
IL12711496A IL127114A (en) 1995-01-30 1996-01-30 Compounds useful as intermediates for preparing pharmaceutically active substituted heterocyclic compounds
AT96902305T ATE222251T1 (en) 1995-01-30 1996-01-30 SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
NZ301285A NZ301285A (en) 1995-01-30 1996-01-30 Heterocyclic neurokinin receptor antagonists, preparation and intermediates thereof
US08/703,729 US5780466A (en) 1995-01-30 1996-08-27 Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present
US08/820,716 US5869663A (en) 1995-01-30 1997-03-18 Substituted heterocyclic compounds
BR1100937-3A BR1100937A (en) 1995-01-30 1997-05-14 Compound, processes for its preparation and obtaining, and pharmaceutical compositions
NO973479A NO308795B1 (en) 1995-01-30 1997-07-29 Substituted heterocyclic compounds and pharmaceutical compositions containing the same
FI973148A FI973148A (en) 1995-01-30 1997-07-29 Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
US09/004,454 US6011154A (en) 1995-01-30 1998-01-08 Substituted heterocyclic compounds, method of preparing them and pharmaceutical compositions in which they are present
HK02103621.9A HK1041881B (en) 1995-01-30 1998-02-10 Substituted heterocyclic compounds, their process of preparation and pharmaceutical compositions containing them
US09/175,331 US6242637B1 (en) 1995-01-30 1998-10-20 Substituted heterocylic compounds, method of preparing them and pharmaceutical compositions in which they are present
US09/175,332 US5977359A (en) 1995-01-30 1998-10-20 Substituted heterocyclic compounds, method of preparing them and pharmaceutical compositions in which they are present
IL12711498A IL127114A0 (en) 1995-01-30 1998-11-18 Substituted heterocyclic compounds
JP2000342571A JP3357660B2 (en) 1995-01-30 2000-11-09 Substituted heterocyclic compounds
JP2000342606A JP2001131171A (en) 1995-01-30 2000-11-09 Pharmaceutical composition
CNB011163402A CN1136189C (en) 1995-01-30 2001-04-11 Substd heterocyclic compounds preparing method thereof and pharmaceutical composition contg. them
CNB011163410A CN1179954C (en) 1995-01-30 2001-04-11 Substd. heterocyclic compounds, preparing process thereof and pharmaceutical composition contg them
JP2001339406A JP3943369B2 (en) 1995-01-30 2001-11-05 Substituted cyclic compounds
CNB011431032A CN1202093C (en) 1995-01-30 2001-12-07 Substituted heterocyclic compound
ARP020101908A AR036027A2 (en) 1995-01-30 2002-05-23 A SUBSTITUTED HETEROCICLIC COMPOUND, PROCEDURE AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING SUCH COMPOUND
CY0300053A CY2369B1 (en) 1995-01-30 2003-08-04 Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same.
CY0500044A CY2537B1 (en) 1995-01-30 2005-08-02 Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9501016A FR2729952B1 (en) 1995-01-30 1995-01-30 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
FR2729952A1 FR2729952A1 (en) 1996-08-02
FR2729952B1 true FR2729952B1 (en) 1997-04-18

Family

ID=9475613

Family Applications (2)

Application Number Title Priority Date Filing Date
FR9501016A Expired - Fee Related FR2729952B1 (en) 1995-01-30 1995-01-30 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR9508046A Expired - Fee Related FR2729953B1 (en) 1995-01-30 1995-07-04 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR9508046A Expired - Fee Related FR2729953B1 (en) 1995-01-30 1995-07-04 SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (4)

Country Link
CN (2) CN101230008A (en)
BR (1) BR1100937A (en)
FR (2) FR2729952B1 (en)
ZA (1) ZA96694B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU224225B1 (en) * 1995-12-01 2005-06-28 Sankyo Co. Ltd. Heterocyclic compounds having tachykinin receptor antagonist activity, their preparation, and their use for the preparation of pharmaceutical compositions
CN114516814B (en) * 2020-11-19 2024-02-20 中国科学院大连化学物理研究所 Catalytic asymmetric preparation method of chiral quaternary carbon alpha-amino acid ester compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE903957A1 (en) * 1989-11-06 1991-05-08 Sanofi Sa Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
UA41251C2 (en) * 1990-01-04 2001-09-17 Пфайзер, Інк. Hydrogenated nitrogen-containing heterocyclic substances, piperidine derivatives, pharmaceutical composition and method for inhibiting activity of p substance
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical compositions containing them
FR2676055B1 (en) * 1991-05-03 1993-09-03 Sanofi Elf AMINO POLYCYCLIC COMPOUNDS AND THEIR ENANTIOMERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2676054B1 (en) * 1991-05-03 1993-09-03 Sanofi Elf NOVEL N-ALKYLENEPIPERIDINO COMPOUNDS AND THEIR ENANTIOMERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2688219B1 (en) * 1992-03-03 1994-07-08 Sanofi Elf AMATONIUM QUATERNARY SALTS OF AMINO AROMATIC COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2696178B1 (en) * 1992-09-30 1994-12-30 Sanofi Elf Quaternary basic amides, process for their preparation and pharmaceutical compositions containing them.

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FR2729952A1 (en) 1996-08-02
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CN1821241A (en) 2006-08-23
FR2729953B1 (en) 1997-08-01

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