FR2691068A1 - Gel for breast prosthesis - Google Patents

Gel for breast prosthesis Download PDF

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Publication number
FR2691068A1
FR2691068A1 FR9214012A FR9214012A FR2691068A1 FR 2691068 A1 FR2691068 A1 FR 2691068A1 FR 9214012 A FR9214012 A FR 9214012A FR 9214012 A FR9214012 A FR 9214012A FR 2691068 A1 FR2691068 A1 FR 2691068A1
Authority
FR
France
Prior art keywords
gel
cellulose
water
breast prosthesis
breast prostheses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR9214012A
Other languages
French (fr)
Inventor
Arion Henri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PCT/FR1993/000464 priority Critical patent/WO1993023089A1/en
Priority to AU40755/93A priority patent/AU4075593A/en
Publication of FR2691068A1 publication Critical patent/FR2691068A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/04—Materials or treatment for tissue regeneration for mammary reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A gel for filling a breast prosthesis comprises 3-12%, to give the required viscosity, of a water-compatible cellulose cpd., e.g., methyl-cellulose, hydroxymethylcellulose or hydroxyphenylcellulose, in water or physiological serum.

Description

GEL POUR PROTHESES MAMMAIRE
DESCRIPTION
Les protheses mammaires remplies de gel sont connues . Elles sont faite d'une poche fine d'élastomère silicone remplie d'un gel ayant à peu pres la consistance de la glande mammaire
Ce gel est le plus souvent constitué d'un élastomère silicone partiellement polymérise a froid dont l'un des constituants a été melange avec une huile de haute viscosite pour obtenir les qualites physiques desirées
Lors d'une rupture accidentelle de la poche , les chaines libres silicones font géneralement l'objet d'une phagocytose et d'une réaction inflammatoire (type " a corps étranger " ) dénommée siliconome
De plus il semble que ces chaines libres soient capables de migrer dans l'organisme et seraient la cause d'une pathologie nouvelle
La présente invention est une application nouvelle de la cellulose et de ses dérivés à la fabrication des protheses mammaires
Un nouveau gel de remplissage des protheses mammaires est un gel aqueux constitue par un mélange d'un composé hydro compatible de la cellulose tel que methyl cellulose , hydroxymethyl cellulose hydroxyphenyl cellulose...avec de l'eau ou du serum physiologique dans une propotion de 3 à 12 % dans l'eau pour obtenir la viscosité désirée
Pour exemple non limitatif , le gel decrit est un mélange de 97% de sérum physiologique ( eau + 9 pour mille de chlorure de sodium ) avec 3% de methyl cellulose
Ce gel a les avantages suivant ... GEL FOR BREAST PROSTHESES
DESCRIPTION
Gel-filled breast prostheses are known. They are made of a thin pocket of silicone elastomer filled with a gel having roughly the consistency of the mammary gland
This gel is most often made up of a partially cold polymerized silicone elastomer, one of the constituents of which has been mixed with a high viscosity oil to obtain the desired physical qualities.
During an accidental rupture of the pocket, the free silicone chains are generally subject to phagocytosis and an inflammatory reaction ("foreign body" type) called siliconomia
In addition, it seems that these free chains are capable of migrating in the organism and are the cause of a new pathology.
The present invention is a new application of cellulose and its derivatives for the manufacture of breast prostheses
A new gel for filling breast prostheses is an aqueous gel constituted by a mixture of a hydro-compatible cellulose compound such as methyl cellulose, hydroxymethyl cellulose hydroxyphenyl cellulose ... with water or physiological serum in a propotion of 3 to 12% in water to obtain the desired viscosity
For nonlimiting example, the gel described is a mixture of 97% of physiological serum (water + 9 per thousand of sodium chloride) with 3% of methyl cellulose
This gel has the following advantages ...

Il est stable dans le temps et à 370C å la fois physiquement et chimiquement Les celluloses et leurs dérivés ont fait depuis longtemps la preuve de leur innocuité en chirurgie
Il s'agit d'un corps solide donc sans chaines libres ou d'un poids moléculaire extrêmement grand ne permettant pas leur migration
Le gel est constitué a 97% d'eau qui représente les seules molécules libres du gel
Enfin le changement d'une prothese accidentellement rompue se ferait avec une beaucoup plus grande facilité . En effet contrairement au gel de silicone , un simple lavage des espaces décollés suffirait pour remettre en place une prothese neuve It is stable over time and at 370C both physically and chemically Celluloses and their derivatives have long proven their safety in surgery
It is a solid body therefore without free chains or of an extremely large molecular weight not allowing their migration
The gel consists of 97% water which represents the only free molecules of the gel
Finally, changing an accidentally ruptured prosthesis would be done with much greater ease. In fact, unlike silicone gel, a simple washing of the detached spaces would be enough to replace a new prosthesis

Claims (1)

REVENDICATIONS Gel pour le remplissage de prothèses mammaires caractérisé en ce qu'il est constitué par un mélange d'un composé hydro compatible de la cellulose tel que methyl cellulose , hydroxymethyl cellulose hydroxyphenyl cellulose...avec de l'eau ou du serum physiologique dans une propotion de 3 à 12 % dans l'eau pour obtenir la viscosité désirée  Gel for filling breast prostheses characterized in that it consists of a mixture of a hydro-compatible cellulose compound such as methyl cellulose, hydroxymethyl cellulose hydroxyphenyl cellulose ... with water or physiological saline in a 3 to 12% propotion in water to obtain the desired viscosity
FR9214012A 1992-05-14 1992-11-16 Gel for breast prosthesis Pending FR2691068A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/FR1993/000464 WO1993023089A1 (en) 1992-05-14 1993-05-13 Breast prosthesis gel
AU40755/93A AU4075593A (en) 1992-05-14 1993-05-13 Breast prosthesis gel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9206153 1992-05-14

Publications (1)

Publication Number Publication Date
FR2691068A1 true FR2691068A1 (en) 1993-11-19

Family

ID=9429995

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9214012A Pending FR2691068A1 (en) 1992-05-14 1992-11-16 Gel for breast prosthesis

Country Status (1)

Country Link
FR (1) FR2691068A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0727232A2 (en) * 1995-02-14 1996-08-21 Mentor Corporation Filling material for soft tissue implant prostheses and implants made therewith
EP0784987A3 (en) * 1996-01-16 1999-04-07 Mentor Corporation Method of making in situ filler material for mammary, penile and testicular prosthesis and tissue expanders
US5941909A (en) * 1995-02-14 1999-08-24 Mentor Corporation Filling material for soft tissue implant prostheses and implants made therewith

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU929093A1 (en) * 1980-04-01 1982-05-23 Экспериментальный Завод Министерства Социального Обеспечения Рсфср Method of producing artificial mammary gland
US4778465A (en) * 1985-11-06 1988-10-18 Wilkins Ebtisam S Surgically implantable areola and nipple prosthesis
WO1990004971A1 (en) * 1988-11-03 1990-05-17 M.D.R. Group, Inc. Improved viscoelastic fluid for use in surgery and other therapies and method of using same
ZA896918B (en) * 1988-09-09 1990-06-27 Natural Form Cc Breast prosthesis and method of making it

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU929093A1 (en) * 1980-04-01 1982-05-23 Экспериментальный Завод Министерства Социального Обеспечения Рсфср Method of producing artificial mammary gland
US4778465A (en) * 1985-11-06 1988-10-18 Wilkins Ebtisam S Surgically implantable areola and nipple prosthesis
ZA896918B (en) * 1988-09-09 1990-06-27 Natural Form Cc Breast prosthesis and method of making it
WO1990004971A1 (en) * 1988-11-03 1990-05-17 M.D.R. Group, Inc. Improved viscoelastic fluid for use in surgery and other therapies and method of using same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPIL Week 8313, Derwent Publications Ltd., London, GB; AN 83-31383K & SU-A-929 093 (SOCIAL SERVICE EXPE) *
DATABASE WPIL Week 9040, Derwent Publications Ltd., London, GB; AN 90-305251 & ZA-A-8 906 918 (NATURAL FORM) *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0727232A2 (en) * 1995-02-14 1996-08-21 Mentor Corporation Filling material for soft tissue implant prostheses and implants made therewith
EP0727232A3 (en) * 1995-02-14 1996-11-06 Mentor Corp Filling material for soft tissue implant prostheses and implants made therewith
US5658329A (en) * 1995-02-14 1997-08-19 Mentor Corporation Filling material for soft tissue implant prostheses and implants made therewith
US5941909A (en) * 1995-02-14 1999-08-24 Mentor Corporation Filling material for soft tissue implant prostheses and implants made therewith
EP0784987A3 (en) * 1996-01-16 1999-04-07 Mentor Corporation Method of making in situ filler material for mammary, penile and testicular prosthesis and tissue expanders

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