FR2687686B1 - Enzyme destinee a la fragmentation du n-acetylheparosane, obtention des preparations contenant cette enzyme et procedes de fragmentation utilisant cette enzyme. - Google Patents

Enzyme destinee a la fragmentation du n-acetylheparosane, obtention des preparations contenant cette enzyme et procedes de fragmentation utilisant cette enzyme.

Info

Publication number
FR2687686B1
FR2687686B1 FR9202255A FR9202255A FR2687686B1 FR 2687686 B1 FR2687686 B1 FR 2687686B1 FR 9202255 A FR9202255 A FR 9202255A FR 9202255 A FR9202255 A FR 9202255A FR 2687686 B1 FR2687686 B1 FR 2687686B1
Authority
FR
France
Prior art keywords
enzyme
fragmentation
acetylheparosane
preparations containing
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9202255A
Other languages
English (en)
Other versions
FR2687686A1 (fr
Inventor
Marc Louis Victor Salome
Philippe Lelong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elf Sanofi SA
Original Assignee
Elf Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elf Sanofi SA filed Critical Elf Sanofi SA
Priority to FR9202255A priority Critical patent/FR2687686B1/fr
Priority to CA002090087A priority patent/CA2090087A1/fr
Priority to US08/020,396 priority patent/US5482844A/en
Priority to MX9300966A priority patent/MX9300966A/es
Priority to EP93400478A priority patent/EP0558411A1/fr
Priority to JP5039066A priority patent/JPH0638748A/ja
Priority to HU9300535A priority patent/HU217685B/hu
Publication of FR2687686A1 publication Critical patent/FR2687686A1/fr
Application granted granted Critical
Publication of FR2687686B1 publication Critical patent/FR2687686B1/fr
Priority to US08/386,762 priority patent/US5583027A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR9202255A 1992-02-26 1992-02-26 Enzyme destinee a la fragmentation du n-acetylheparosane, obtention des preparations contenant cette enzyme et procedes de fragmentation utilisant cette enzyme. Expired - Lifetime FR2687686B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR9202255A FR2687686B1 (fr) 1992-02-26 1992-02-26 Enzyme destinee a la fragmentation du n-acetylheparosane, obtention des preparations contenant cette enzyme et procedes de fragmentation utilisant cette enzyme.
CA002090087A CA2090087A1 (fr) 1992-02-26 1993-02-22 Enzyme intended for the fragmentation of n-acetylheparosan, production of preparations containing this enzyme and fragmentation processes using this enzyme
US08/020,396 US5482844A (en) 1992-02-26 1993-02-22 Enzyme intended for the fragmentation of N-acetylheparosan, production of preparations containing this enzyme and fragmentation processes using this enzyme
MX9300966A MX9300966A (es) 1992-02-26 1993-02-23 Enzima para fragmentar n-acetilheparosano, y procedimiento para su obtencion.
EP93400478A EP0558411A1 (fr) 1992-02-26 1993-02-24 Enzyme destinée à la fragmentation du N-acétylhéparosane, obtention des préparations contenant cette enzyme et procédés de fragmentation utilisant cette enzyme
JP5039066A JPH0638748A (ja) 1992-02-26 1993-02-26 Ｎ‐アセチルヘパロサンの断片化用酵素、該酵素を含む調製物の製造、及び、該酵素を使用する断片化法
HU9300535A HU217685B (hu) 1992-02-26 1993-02-26 N-acetil-heparozán fragmentálására szolgáló enzim, eljárás előállítására és fragmentációs eljárás az enzim felhasználásával
US08/386,762 US5583027A (en) 1992-02-26 1995-02-10 Enzyme intended for the fragmentation of N-acetylheparosan, production of preparations containing this enzyme and fragmentation process using this enzyme

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9202255A FR2687686B1 (fr) 1992-02-26 1992-02-26 Enzyme destinee a la fragmentation du n-acetylheparosane, obtention des preparations contenant cette enzyme et procedes de fragmentation utilisant cette enzyme.

Publications (2)

Publication Number Publication Date
FR2687686A1 FR2687686A1 (fr) 1993-08-27
FR2687686B1 true FR2687686B1 (fr) 1994-05-27

Family

ID=9427076

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9202255A Expired - Lifetime FR2687686B1 (fr) 1992-02-26 1992-02-26 Enzyme destinee a la fragmentation du n-acetylheparosane, obtention des preparations contenant cette enzyme et procedes de fragmentation utilisant cette enzyme.

Country Status (7)

Country Link
US (2) US5482844A (fr)
EP (1) EP0558411A1 (fr)
JP (1) JPH0638748A (fr)
CA (1) CA2090087A1 (fr)
FR (1) FR2687686B1 (fr)
HU (1) HU217685B (fr)
MX (1) MX9300966A (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2709132B1 (fr) * 1993-08-17 1995-11-17 Sanofi Elf Fragment d'ADN portant le gène codant pour l'enzyme de fragmentation du N-acétylhéparosane et les séquences adjacentes permettant son expression, enzyme recombinée et son utilisation.
JP3712530B2 (ja) * 1998-05-28 2005-11-02 キッコーマン株式会社 新種クリプトコッカス・ノダエンシス、それを用いる耐塩性耐熱性グルタミナーゼの製造法並びにグルタミン酸含量の多い蛋白加水分解物の製造法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3812012A (en) * 1970-11-07 1974-05-21 Hoechst Ag Method of degrading natural plant material with an enzyme preparation
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
US4704360A (en) * 1983-11-30 1987-11-03 Petroleum Fermentations Enzymatic degradation of lipopolysaccharide bioemulsifiers
US4818817A (en) * 1983-11-30 1989-04-04 Petroleum Fermentations N.V. Enzymatic degradation of lipopolysaccharide bioemulsifiers
US5106734A (en) * 1986-04-30 1992-04-21 Novo Nordisk A/S Process of using light absorption to control enzymatic depolymerization of heparin to produce low molecular weight heparin
NL8701342A (nl) * 1987-06-09 1989-01-02 Tno Bifunctionele oligosacchariden alsmede daarvan afgeleide aktieve verbindingen.
EP0333243A3 (fr) * 1988-03-10 1989-09-27 Akzo N.V. Antigène K5 sulfaté et ses fragments

Also Published As

Publication number Publication date
CA2090087A1 (fr) 1993-08-27
MX9300966A (es) 1993-12-01
EP0558411A1 (fr) 1993-09-01
JPH0638748A (ja) 1994-02-15
US5482844A (en) 1996-01-09
FR2687686A1 (fr) 1993-08-27
HU9300535D0 (en) 1993-05-28
HUT68813A (en) 1995-07-28
US5583027A (en) 1996-12-10
HU217685B (hu) 2000-03-28

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Legal Events

Date Code Title Description
ER Errata listed in the french official journal (bopi)

Free format text: 34/93