FR2685638A1 - Compositions for cosmetic and/or dermatological use, comprising a combination of pyrithione zinc, piroctone olamine and a derivative of collagen and of fatty acid - Google Patents

Compositions for cosmetic and/or dermatological use, comprising a combination of pyrithione zinc, piroctone olamine and a derivative of collagen and of fatty acid Download PDF

Info

Publication number
FR2685638A1
FR2685638A1 FR9116406A FR9116406A FR2685638A1 FR 2685638 A1 FR2685638 A1 FR 2685638A1 FR 9116406 A FR9116406 A FR 9116406A FR 9116406 A FR9116406 A FR 9116406A FR 2685638 A1 FR2685638 A1 FR 2685638A1
Authority
FR
France
Prior art keywords
sep
weight
composition according
fatty acid
collagen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9116406A
Other languages
French (fr)
Other versions
FR2685638B1 (en
Inventor
Martin Henry
Valette Louis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biorga SA Laboratoires
Original Assignee
Biorga SA Laboratoires
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biorga SA Laboratoires filed Critical Biorga SA Laboratoires
Priority to FR9116406A priority Critical patent/FR2685638A1/en
Publication of FR2685638A1 publication Critical patent/FR2685638A1/en
Application granted granted Critical
Publication of FR2685638B1 publication Critical patent/FR2685638B1/fr
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/06Emulsions
    • A61K8/068Microemulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4933Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having sulfur as an exocyclic substituent, e.g. pyridinethione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to a composition for cosmetic and/or dermatological use, which composition comprises piroctone olamine, pyrithione zinc, a derivative of collagen and of fatty acid and optionally an antioxidant, preferably vitamin E. The composition of the invention is advantageously used for hygiene and care of skin affected by acne.

Description

La présente invention est relative à des compositions pour l'usage cosmétique et/ou dermatologique, plus particulièrement destinées à l'hygiène et au soin des peaux acnéiques, lesquelles compositions contiennent en tant que principe actif, une association de piroctone olamine et de pyrithione zinc. Les peaux acnéiques résultent d'une association de plusieurs composantes. Au départ existe une hypersécrétion sébacée, accompagnée d'une dyskératinisation qui induit, au niveau des glandes sébacées, une rétention de sébum, provoquant la formation de comédons. La glande sébacée engorgée est un lieu propice à la prolifération de microorganismes : le
Propionibacterium acnes, le staphylocoque, et le Pytirosporum ovale.A ceci viennent s'ajouter une irritation puis une inflammation déclenchées par de nombreux facteurs, notamment par la présence d'acides gras libres qui subissent des oxydations et peroxydations, entraînant la formation de radicaux libres, générateurs de phénomènes inflammatoires. L'ensemble de ces phénomènes entraîne la formation des pustules caractéristiques de l'acné.
The present invention relates to compositions for cosmetic and / or dermatological use, more particularly intended for the hygiene and care of acne skin, which compositions contain, as active ingredient, a combination of piroctone olamine and pyrithione zinc . Acne skin results from a combination of several components. Initially exists a sebaceous hypersecretion, accompanied by a dyskeratinization which induces, at the level of the sebaceous glands, a retention of sebum, causing the formation of comedones. The congested sebaceous gland is a place conducive to the proliferation of microorganisms: the
Propionibacterium acnes, staphylococcus, and Pytirosporum ovale. In addition, irritation and inflammation are triggered by many factors, including the presence of free fatty acids that undergo oxidation and peroxidation, resulting in the formation of free radicals. , generators of inflammatory phenomena. All of these phenomena lead to the formation of the pustules characteristic of acne.

Les traitements antiacnéiques classiques associent généralement l'utilisation, d'une part, d'antibiotiques et d'antiseptiques, agissant sur la composante infectieuse, et d'autre part, de kératolytiques, agissant sur la rétention de sébum. Conventional anti-acne treatments generally combine the use, on the one hand, of antibiotics and antiseptics, acting on the infectious component, and on the other hand, keratolytics, acting on the retention of sebum.

En ce qui concerne la composante infectieuse, les traitements antibiotiques et antiseptiques préconisés ont essentiellement pour but la diminution de la flore bactérienne, généralement considérée comme responsable de la surinfection des glandes sébacées. Toutefois, la diminution de la flore bactérienne ainsi provoquée entraîne la prolifération de Pityrosporum ovale. Or, il semble que l'infection par Pityrosporum ovale joue également un rôle important dans la pathogenèse de l'acné, et en particulier dans le déclenchement du processus inflammatoire ce microorganisme est en effet en grande partie responsable des oxydations et peroxydations des acides gras accumulés dans les glandes sébacées. Regarding the infectious component, the recommended antibiotic and antiseptic treatments are mainly aimed at reducing the bacterial flora, generally considered to be responsible for superinfection of the sebaceous glands. However, the decrease in the bacterial flora thus caused leads to the proliferation of Pityrosporum ovale. However, it seems that Pityrosporum ovale infection also plays an important role in the pathogenesis of acne, and in particular in triggering the inflammatory process this microorganism is indeed largely responsible for oxidation and peroxidation of accumulated fatty acids. in the sebaceous glands.

En ce qui concerne la rétention de sébum, les ératolytiques permettent la dissolution du bouchon sébacé ; ils provoquent toutefois un amincissement de la couche cornée, ce qui entraîne une déshydratation et un dessèchement de la peau, et une augmentation de sa sensibilité aux agressions d'origines diverses. Cet état est en outre accentué par l'effet irritant de certains des traitements antiseptiques locaux associés, et parfois par des produits d'hygiène trop agressifs, qui, sous prétexte d'éliminer l'excès de sébum, conduisent à la délipidation de l'épiderme. As regards the retention of sebum, the erratolytics allow the dissolution of the sebaceous plug; however, they cause a thinning of the stratum corneum, resulting in dehydration and drying of the skin, and an increase in its sensitivity to aggression of various origins. This state is further accentuated by the irritating effect of some of the associated local antiseptic treatments, and sometimes by too aggressive hygiene products, which, under the pretext of eliminating the excess of sebum, lead to the delipidation of the epidermis.

La présente Invention a pour but de pourvoir à an produit de soin et de traitement des peaux acnéiques, actif au niveau de différents facteurs responsables de la composante inflammatoire de l'acné. The present invention aims to provide an acne skin care and treatment product, active in various factors responsible for the inflammatory component of acne.

L'inventeur a constaté que des compositions comprenant une association de pyrithione zinc, de piroctone olamine, en combinaison avec un agent tensioactif amionique, dérivé de collagène et d'acide gras, étaient particulièrement actives pour prévenir la prolifération de Pityrosporum ovale. The inventor has found that compositions comprising a combination of pyrithione zinc, piroctone olamine, in combination with an amionic surfactant, derived from collagen and fatty acid, were particularly active in preventing the proliferation of Pityrosporum ovale.

La présente invention a pour objet une composition pour l'usage cosmétique et/ou dermatologique, caractérisée en ce qu'elle comprend, en tant que principe actif, une association de piroctone olamine et de pyrithione zinc, et d'un tensio-actif amionique dérivé de collagène et d'acide gras.. The present invention relates to a composition for cosmetic and / or dermatological use, characterized in that it comprises, as active ingredient, a combination of piroctone olamine and pyrithione zinc, and an amionic surfactant. derivative of collagen and fatty acid ..

Selon un mode de réalisation préféré d'une composition conforme à l'invention, ladite composition comprend en outre au moins un agent antioxydant. According to a preferred embodiment of a composition according to the invention, said composition further comprises at least one antioxidant agent.

En effet, l'adjonction d'au moins un agent antioxydant à une composition conforme à l'invention, augmente l'activité anti-irritante et anti-inflammatoire de ladite composition. Indeed, the addition of at least one antioxidant agent to a composition according to the invention increases the anti-irritant and anti-inflammatory activity of said composition.

De manière générale, tous les agents antioxydants piégeant les radicaux libres, permettant d'éviter l'oxydation et la peroxydation des acides gras et compatibles avec une formulation destinée à l'usage dermatologique et/ou cosmétique peuvent être employés. Il est possible de citer, par exemple, et de façon non limitative, la vitamine E et ses dérivés, la vitamine A, la vitamine C, et leurs dérivés, la superoxyde dismutase, l'allopurinol, la cystéine, les flavophérols, les dérivés quinoniques, l'extrait de Gingko biloba, le butylhydroxytoluène, le sélénium, etc... In general, all the antioxidant agents trapping free radicals, making it possible to prevent oxidation and peroxidation of fatty acids and compatible with a formulation intended for dermatological and / or cosmetic use may be employed. It is possible to cite, for example, and without limitation, vitamin E and its derivatives, vitamin A, vitamin C, and their derivatives, superoxide dismutase, allopurinol, cysteine, flavopherols, derivatives quinone, Gingko biloba extract, butylhydroxytoluene, selenium, etc.

De manière avantageuse, l'agent anti-oxydant est la vitamine E, sous forme de micro-émulsion. Advantageously, the antioxidant agent is vitamin E, in the form of a microemulsion.

Selon un mode de réalisation préféré d'une composition conforme à l'invention, elle comprend entre 0,05 et 2%, en poids, de piroctone olamine, entre 0,1 et 3%, en poids, de pyrithione zinc, et entre 5 et 20 %, en poids, de dérivé de collagène et d'acide gras. According to a preferred embodiment of a composition according to the invention, it comprises between 0.05 and 2%, by weight, of piroctone olamine, between 0.1 and 3%, by weight, of pyrithione zinc, and between 5 and 20%, by weight, of collagen derivative and fatty acid.

De façon avantageuse, elle comprend en outre de 0,5 à 10%, en poids, de vitamine E. Advantageously, it also comprises from 0.5 to 10%, by weight, of vitamin E.

La piroctone olamine et la pyrithione zinc peuvent également être associées à d'autres agents antifongiques, antiseptiques et/ou antiséborrhéiques, par exemple des dérivés imidazolés, des dérivés iodés, des dérivés de sélénium, des sels d'undécylénate, des esters d'acide parahydroxybenzoïque, des ammoniums quaternaires, des alcools, l'acide lactique, l'acide borique, la chlorhexidine, l'héxétidine, le soufre, les acides aminés soufrés, les goudrons, des extraits végétaux tels que les extraits d'ortie, de bouleau, d'hamamélis, ainsi que des vitamines A, H, B6. Piroctone olamine and zinc pyrithione can also be combined with other antifungal, antiseptic and / or antiseborrhoeic agents, for example imidazole derivatives, iodinated derivatives, selenium derivatives, undecylenate salts, acid esters and the like. parahydroxybenzoic acid, quaternary ammoniums, alcohols, lactic acid, boric acid, chlorhexidine, hexetidine, sulfur, sulfur amino acids, tars, plant extracts such as nettle extract, birch extract , witch hazel, as well as vitamins A, H, B6.

Les compositions conformes à l'invention permettent la préparation d'un grand nombre de produits destinés à l'usage cosmétique et/ou dermatologique, tels que des crèmes, pommades, lotions, poudres, savons, etc... Lorsque l'association piroctone olamine/pyrithione zinc est utilisée dans des préparations destinées à demeurer sur la peau, telles que des crèmes, on choisira de préférence dans les gammes mentionnées plus haut, les plus faibles concentrations en principes actifs lorsqu'il s'agit de préparation destinées à être rincées, telles que des savons, on choisira des concentrations plus importantes. The compositions according to the invention allow the preparation of a large number of products intended for cosmetic and / or dermatological use, such as creams, ointments, lotions, powders, soaps, etc. When the piroctone association olamine / pyrithione zinc is used in preparations intended to remain on the skin, such as creams, it will preferably be chosen from the ranges mentioned above, the lowest concentrations of active ingredients when it comes to preparation to be rinsed, such as soaps, larger concentrations will be chosen.

De manière avantageuse, les compositions conformes à l'invention sont utilisées pour l'obtention d'un savon dont la composition comprend en outre une base lavante, au moins un agent humectant et/ou hydratant, au moins un agent surgraissant, et, optionnellement, d'autres principes actifs antifongiques, antiseptiques et/ou antiséborrhéiques, des parfums, colorants, agents de texture, et conservateurs appropriés. Advantageously, the compositions in accordance with the invention are used for obtaining a soap whose composition also comprises a washing base, at least one humectant and / or moisturizing agent, at least one superfatting agent, and, optionally , other antifungal, antiseptic and / or antiseborrheic active ingredients, suitable fragrances, colorants, texturizing agents and preservatives.

Les bases lavantes pouvant être utilisées sont constituées d'un ou plusieurs tensio-actifs anioniques, ou d'un ou plusieurs tensio-actifs cationiques, et/ou d'un ou plusieurs tensio-actifs amphotères, la pyrithione zinc formant des complexes avec les tensio-actifs non ioniques ; de préférence seront utilisés des tensioactifs doux, afin d'éviter une délipidation trop importante de l'épiderme. The washing bases that can be used consist of one or more anionic surfactants, or one or more cationic surfactants, and / or one or more amphoteric surfactants, the zinc pyrithione forming complexes with the nonionic surfactants; preferably mild surfactants will be used, in order to avoid too much delipidation of the epidermis.

Parmi les agents humectants et/ou hydratants utilisables dans le cadre de la présente invention, on peut citer : le pidolate de sodium, l'urée, le sorbitol, le glycérol, le N.M.F., les glycosaminoglycannes, le lactate de sodium, les protéines du lait, les sels de guanidine, le collagène, le propylène glycol. Among the humectants and / or moisturizers that can be used in the context of the present invention, mention may be made of: sodium pidolate, urea, sorbitol, glycerol, NMF, glycosaminoglycans, sodium lactate, proteins of the milk, guanidine salts, collagen, propylene glycol.

Comme agents surgraissants, on peut utiliser par exemple des dérivés d'huiles végétales, animales, ou minérales, ainsi que des huiles de synthèse ; la partie hydrophobe de certains tensio-actifs joue également le rôle d'agent surgraissant. As superfatting agents, it is possible to use, for example, vegetable, animal or mineral oil derivatives, as well as synthetic oils; the hydrophobic part of certain surfactants also acts as a superfatting agent.

De façon avantageuse, le pH du savon obtenu est compris entre 4 et 7. Il est possible d'utiliser, dans ce but, de l'acide borique, de l'acide sorbique, ou de l'acide citrique. Advantageously, the pH of the soap obtained is between 4 and 7. It is possible to use, for this purpose, boric acid, sorbic acid, or citric acid.

Un savon liquide conforme à la présente invention comprend, avantageusement, entre 0,5 et 2% en poids de pyrithione zinc, entre 0,3 et 1% en poids de piroctone olamine, entre 5 et 20 %, en poids, de dérivé de collagène et d'acide gras, entre 0,5 et 20 % en poids de vitamine E, entre 1 et 10% en poids d'agents surgraissants, entre 1 et 10% en poids d'agents hydratants, entre 10 et 40% en poids de tensio-actifs anioniques et/ou de tensio-actifs amphotères doux. A liquid soap according to the present invention comprises, advantageously, between 0.5 and 2% by weight of pyrithione zinc, between 0.3 and 1% by weight of piroctone olamine, between 5 and 20%, by weight, of collagen and fatty acid, between 0.5 and 20% by weight of vitamin E, between 1 and 10% by weight of superfatting agents, between 1 and 10% by weight of moisturizing agents, between 10 and 40% by weight, weight of anionic surfactants and / or mild amphoteric surfactants.

Ce gel nettoyant convient particulièrement pour l'hygiène des peaux acnéiques. En effet, outre les effets antifongiques et antiséborrhéiques de l'association piroctone olamine/pyrithione zinc, et l'action antioxydante de la vitamine E, la formulation de ce gel permet de nettoyer la peau sans l'agresser, d'éviter une délipidation excessive et de restaurer une bonne hydratation. This cleaning gel is particularly suitable for the hygiene of acne skin. Indeed, in addition to the antifungal and antiseborrheic effects of the association piroctone olamine / pyrithione zinc, and the antioxidant action of vitamin E, the formulation of this gel makes it possible to clean the skin without attacking it, to avoid excessive delipidation and restore a good hydration.

La présente invention sera mieux comprise à l'aide du complément de description qui va suivre, qui donne en exemple la préparation d'un savon liquide conforme à l'invention. The present invention will be better understood with the aid of the additional description which follows, which gives as an example the preparation of a liquid soap according to the invention.

Il doit être bien entendu, toutefois, que ces exemples sont donnés uniquement à titre d'illustration de l'objet de l'invention, dont ils ne constituent en aucune manière une limitation.  It should be understood, however, that these examples are given solely by way of illustration of the object of the invention, of which they in no way constitute a limitation.

EXEMPLE 1 : Préparation d'une composition conforme à l'invention, destinée à être utilisée comme savon
TABLEAU 1

Figure img00060001
EXAMPLE 1 Preparation of a Composition According to the Invention for Use as a Soap
TABLE 1
Figure img00060001

<tb> DENOMINATION <SEP> DENOMINATION <SEP> ION <SEP>
<tb> COMMERCIALE <SEP> CHIMIQUE <SEP> (p/p) <SEP>
<tb> CETIOL <SEP> HE <SEP> PEG-7-GLYCERYL <SEP> COCOATE <SEP> 1
<tb> TEXAPON <SEP> N <SEP> 40 <SEP> ) <SEP> <SEP> 9
<tb> TEXAPON <SEP> ASV <SEP> ) <SEP> LAURYL <SEP> ETHER <SEP> SULFATE <SEP> DE <SEP> Na <SEP> 9,5
<tb> GELIDERM <SEP> 3000 <SEP> S <SEP> DERIVE <SEP> DE <SEP> COLLAGENE <SEP> ET <SEP> 10
<tb> <SEP> D'ACIDE <SEP> GRAS
<tb> COMPERLAN <SEP> KD <SEP> DIETHANOLAMIDE <SEP> DE <SEP> COPRAH <SEP> 2
<tb> REWOTERIC <SEP> AM2CNM <SEP> COCOAMPHOGLYCINATE <SEP> 5
<tb> <SEP> GLYCERINE <SEP> 7
<tb> VEEGUM <SEP> HS <SEP> 2
<tb> GLYDANT <SEP> DIMETHYL <SEP> HYDANTOINE <SEP> 0,3
<tb> <SEP> CHLORURE <SEP> DE <SEP> Na <SEP> 1
<tb> <SEP> ACIDE <SEP> CITRIQUEa <SEP> 0,33
<tb> <SEP> VITAMINE <SEP> E <SEP> (MICRO-EMULSION) <SEP> 2
<tb> ZINCOMADINE <SEP> A <SEP> 48 <SEP> % <SEP> PYRITHIONE <SEP> ZINC <SEP> 0,5
<tb> <SEP> PIROCTONE <SEP> OLAMINE <SEP> 0,3
<tb> <SEP> PARFUM <SEP> 0,02
<tb> <SEP> COLORANTb <SEP> 0,15
<tb> <SEP> EAU <SEP> DEMINERALISEE <SEP> QSP <SEP> 100
<tb> a: solution à 10% b: solution à 0,5%
Le savon est préparé, à partir des composants indiqués au tableau I ci-dessus, selon la procédure suivante
- on porte l'eau à ébullition dans une première cuve, et l'on maintient l'ébullition pendant 15 minutes ; après refroidissement à 60"C, on procède à la dissolution du chlorure de sodium et du glydant ;
- on introduit successivement, dans une deuxième cuve en inox, et sous agitation planétaire, les composants suivants :Geliderm 3000 S, Texapon ASV,
Texapon N40, Glycérine, Veegum HS, Comperlan KD, Vitamine
E, Cétiol HE, Rewoteric AM2CNM ;
- on mélange le contenu des deux cuves, sous agitation modérée, et on refroidit à une température de 25C ; on ajoute, sous agitation planétaire, la pyrithione zinc, et la piroctone olamine, on ajoute également, si on le souhaite, le parfum ;
- après complète dissolution, on ajuste le pH à 6 par addition de la solution d'acide citrique ;
- Si on le désire, on ajoute le colorant.
<tb> DENOMINATION <SEP> NAME <SEP> ION <SEP>
<tb> COMMERCIAL <SEP> CHEMICAL <SEP> (w / w) <SEP>
<tb> CETIOL <SEP> HE <SEP> PEG-7-GLYCERYL <SEP> COCOATE <SEP> 1
<tb> TEXAPON <SEP> N <SEP> 40 <SEP>) <SEP><SEP> 9
<tb> TEXAPON <SEP> ASV <SEP>) <SEP> LAURYL <SEP> ETHER <SEP> SULFATE <SEP> FROM <SEP> Na <SEP> 9.5
<tb> GELIDERM <SEP> 3000 <SEP> S <SEP> DERIVE <SEP> FROM <SEP> COLLAGEN <SEP> AND <SEP> 10
<tb><SEP> OF ACID <SEP> FAT
<tb> COMPERLAN <SEP> KD <SEP> DIETHANOLAMIDE <SEP> FROM <SEP> COPRAH <SEP> 2
<tb> REWOTERIC <SEP> AM2CNM <SEP> COCOAMPHOGLYCINATE <SEP> 5
<tb><SEP> GLYCERINE <SEP> 7
<tb> VEEGUM <SEP> HS <SEP> 2
<tb> GLYDANT <SEP> DIMETHYL <SEP> HYDANTOIN <SEP> 0.3
<tb><SEP> CHLORIDE <SEP> FROM <SEP> Na <SEP> 1
<tb><SEP> ACID <SEP> CITRICO <SEP> 0.33
<tb><SEP> VITAMIN <SEP> E <SEP> (MICRO-EMULSION) <SEP> 2
<tb> ZINCOMADINE <SEP> A <SEP> 48 <SEP>% <SEP> PYRITHIONE <SEP> ZINC <SEP> 0.5
<tb><SEP> PIROCTONE <SEP> OLAMINE <SEP> 0.3
<tb><SEP> PERFUME <SEP> 0.02
<tb><SEP> COLORANTb <SEP> 0.15
<tb><SEP> WATER <SEP> DEMINERALIZED <SEP> QSP <SEP> 100
<tb> a: 10% solution b: 0.5% solution
The soap is prepared from the components indicated in Table I above, according to the following procedure
the water is boiled in a first tank and the boiling is maintained for 15 minutes; after cooling to 60 ° C, the sodium chloride and the glydant are dissolved;
the following components are successively introduced into a second stainless steel tank and under planetary agitation: Geliderm 3000 S, Texapon ASV,
Texapon N40, Glycerin, Veegum HS, Comperlan KD, Vitamin
E, Cetiol HE, Rewoteric AM2CNM;
- The contents of the two tanks are mixed, with moderate stirring, and cooled to a temperature of 25C; zinc pyrithione and piroctone olamine are added with planetary stirring, the perfume is also added if desired;
after complete dissolution, the pH is adjusted to 6 by addition of the citric acid solution;
If desired, the dye is added.

Ainsi que cela ressort de ce qui précède, l'invention ne se limite nullement à ceux de ses modes de mise en oeuvre, de réalisation et d'application qui viennent d'être décrits de façon plus explicite ; elle en embrasse au contraire toutes les variantes qui peuvent venir à l'esprit du technicien en la matière, sans s'écarter du cadre, ni de la portée, de la présente invention.  As is apparent from the above, the invention is not limited to those of its modes of implementation, implementation and application which have just been described more explicitly; it encompasses all the variants that may come to the mind of the technician in the field, without departing from the scope or scope of the present invention.

Claims (9)

REVENDICATIONS 1) Composition antiacnéique, caractérisée en ce qu'elle comprend de la piroctone olamine, de la pyrithione zinc, et un tensio-actif amionique dérivé de collagène et d'acide gras. 1) Anti-acne composition, characterized in that it comprises piroctone olamine, pyrithione zinc, and an amionic surfactant derived from collagen and fatty acid. 2) Composition selon la revendication 1, caractérisée en ce qu'elle comprend en outre un antioxydant. 2) Composition according to claim 1, characterized in that it further comprises an antioxidant. 3) Composition selon la Revendication 2, caractérisée en ce que l'anti-oxydant est la vitamine E, sous forme de micro-émulsion. 3) Composition according to claim 2, characterized in that the antioxidant is vitamin E, in the form of microemulsion. 4) Composition selon l'une quelconque des 4) Composition according to any one of Revendications 1 à 3, caractérisée en ce qu'elle comprend, en outre, d'autres principes actifs antifongiques, antiseptiques et/ou antiséborrhétiquesClaims 1 to 3, characterized in that it further comprises other antifungal, antiseptic and / or antiseborrhetic active ingredients. 5) Composition selon l'une quelconque des 5) Composition according to any one of Revendications 1 à 4, caractérisée en ce qu'elle comprend entre 0,05 et 2%, en poids, de piroctone olamine, entre 0,1 et 3%, en poids, de pyrithione zinc, et entre 5 et 20 %, en poids, de dérivé de collagène et d'acide gras.Claims 1 to 4, characterized in that it comprises between 0.05 and 2%, by weight, of piroctone olamine, between 0.1 and 3%, by weight, of pyrithione zinc, and between 5 and 20%, weight, collagen derivative and fatty acid. 6) Composition selon l'une quelconque des 6) Composition according to any one of Revendications 2 à 5, caractérisée en ce qu'elle comprend de 0,5 à 10%, en poids, de vitamine E.Claims 2 to 5, characterized in that it comprises from 0.5 to 10%, by weight, of vitamin E. 7) Composition selon l'une quelconque des revendications 1 à 6, pour l'utilisation comme savon, ladite composition étant caractérisée en ce qu'elle comprend en outre une base lavante, au moins un agent humectant et/ou hydratant, au moins un agent surgraissant, et, optionnellement des parfums, colorants, agents de texture, et conservateurs appropriés. 7) Composition according to any one of claims 1 to 6, for use as a soap, said composition being characterized in that it further comprises a washing base, at least one humectant and / or moisturizing agent, at least one superfatting agent, and optionally suitable fragrances, colorants, texturizers, and preservatives. 8) Composition selon la revendication 7, caractérisée en ce que son pH est compris entre 4 et 7. 8) Composition according to claim 7, characterized in that its pH is between 4 and 7. 9) Composition selon l'une quelconque des revendications 7 ou 8, caractérisée en ce qu'elle est constituée par le mélange, dans une quantité d'eau appropriée, de : entre 0,5 et 2% en poids de pyrithione zinc, entre 0,3 et 1% en poids de piroctone olamine, entre 5 et 20 % en poids de dérivé de collagène et d'acide gras, entre 0,5 et 10% en poids de vitamine E, entre 1 et 10% en poids d'agents surgraissants, entre 1 et 10% en poids d'agents hydratants, entre 10 et 40% en poids de tensio-actifs anioniques et/ou de tensio actifs amphotères doux.  9) Composition according to any one of claims 7 or 8, characterized in that it consists of the mixture, in an appropriate amount of water, of: between 0.5 and 2% by weight of pyrithione zinc, between 0.3 and 1% by weight of piroctone olamine, between 5 and 20% by weight of collagen derivative and of fatty acid, between 0.5 and 10% by weight of vitamin E, between 1 and 10% by weight of surfactants, between 1 and 10% by weight of moisturizing agents, between 10 and 40% by weight of anionic surfactants and / or mild amphoteric surfactants.
FR9116406A 1991-12-31 1991-12-31 Compositions for cosmetic and/or dermatological use, comprising a combination of pyrithione zinc, piroctone olamine and a derivative of collagen and of fatty acid Granted FR2685638A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9116406A FR2685638A1 (en) 1991-12-31 1991-12-31 Compositions for cosmetic and/or dermatological use, comprising a combination of pyrithione zinc, piroctone olamine and a derivative of collagen and of fatty acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9116406A FR2685638A1 (en) 1991-12-31 1991-12-31 Compositions for cosmetic and/or dermatological use, comprising a combination of pyrithione zinc, piroctone olamine and a derivative of collagen and of fatty acid

Publications (2)

Publication Number Publication Date
FR2685638A1 true FR2685638A1 (en) 1993-07-02
FR2685638B1 FR2685638B1 (en) 1995-04-21

Family

ID=9420726

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9116406A Granted FR2685638A1 (en) 1991-12-31 1991-12-31 Compositions for cosmetic and/or dermatological use, comprising a combination of pyrithione zinc, piroctone olamine and a derivative of collagen and of fatty acid

Country Status (1)

Country Link
FR (1) FR2685638A1 (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19537509A1 (en) * 1995-09-27 1997-04-10 Egsto Pharm Pharmazeutische Pr Prods. for treating irritated skin
WO1998013043A1 (en) * 1996-09-27 1998-04-02 Hoechst Aktiengesellschaft Use of 1-hydroxy-2-pyridones for the treatment of skin diseases
EP1130012A2 (en) * 2000-02-29 2001-09-05 VaMa FarmaCosmetica S.r.l. A process for the preparation of amphoglycinates from vegetable oils and butters and the use thereof
US7018656B2 (en) 1996-09-27 2006-03-28 Aventis Pharma Deutschland Gmbh Antimycotic gel with high active substance release
WO2006053708A1 (en) * 2004-11-22 2006-05-26 Unilever Plc Improved detergent composition
EP1406576B2 (en) 2001-07-18 2011-06-29 Unilever PLC Hair and/or scalp treatment compositions
US7981909B2 (en) 1996-09-27 2011-07-19 Medicis Pharmaceutical Corporation Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis
DE102010013275A1 (en) * 2010-03-29 2011-09-29 Beiersdorf Ag Microbiologically stable, application-friendly W / O preparations
WO2013025769A3 (en) * 2011-08-15 2014-04-10 The Procter & Gamble Company Methods of enhancing skin hydration and improving non-diseased skin
US20150374600A1 (en) * 2009-02-11 2015-12-31 Joseph F. Walsh Methods and preparations that treat human hair loss
WO2016179446A1 (en) * 2015-05-06 2016-11-10 The Procter & Gamble Company Methods of cosmetically treating skin conditions with a cosmetic personal cleansing composition
US10201481B2 (en) 2014-03-07 2019-02-12 The Procter & Gamble Company Personal care compositions and methods of making same

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018049557A1 (en) * 2016-09-13 2018-03-22 The Procter & Gamble Company Methods of altering the microbiota composition of skin
EP4127645A1 (en) 2020-03-24 2023-02-08 The Procter & Gamble Company Methods for testing skin samples

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2123148A1 (en) * 1971-01-25 1972-09-08 Contier Marcel Anti seborrhoeic compsns - contg cadmium sulphide and zinc pyridine thione
EP0217635A2 (en) * 1985-09-27 1987-04-08 The Procter & Gamble Company Hair treatment
FR2618072A1 (en) * 1987-07-17 1989-01-20 Oreal PHARMACEUTICAL AND COSMETIC COMPOSITIONS BASED ON PYRIDONES AND ANTIBACTERIAL AGENTS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2123148A1 (en) * 1971-01-25 1972-09-08 Contier Marcel Anti seborrhoeic compsns - contg cadmium sulphide and zinc pyridine thione
EP0217635A2 (en) * 1985-09-27 1987-04-08 The Procter & Gamble Company Hair treatment
FR2618072A1 (en) * 1987-07-17 1989-01-20 Oreal PHARMACEUTICAL AND COSMETIC COMPOSITIONS BASED ON PYRIDONES AND ANTIBACTERIAL AGENTS

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19537509A1 (en) * 1995-09-27 1997-04-10 Egsto Pharm Pharmazeutische Pr Prods. for treating irritated skin
WO1998013043A1 (en) * 1996-09-27 1998-04-02 Hoechst Aktiengesellschaft Use of 1-hydroxy-2-pyridones for the treatment of skin diseases
US6469033B1 (en) 1996-09-27 2002-10-22 Aventis Pharma Deutschland Gmbh Use of 1-hydroxy-2-pyridones for the treatment of skin diseases
US7018656B2 (en) 1996-09-27 2006-03-28 Aventis Pharma Deutschland Gmbh Antimycotic gel with high active substance release
US7026337B2 (en) 1996-09-27 2006-04-11 Aventis Pharma Deutschland Gmbh Antimycotic gel having high active compound release
US7981909B2 (en) 1996-09-27 2011-07-19 Medicis Pharmaceutical Corporation Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis
EP1130012A2 (en) * 2000-02-29 2001-09-05 VaMa FarmaCosmetica S.r.l. A process for the preparation of amphoglycinates from vegetable oils and butters and the use thereof
EP1130012A3 (en) * 2000-02-29 2003-10-15 VaMa FarmaCosmetica S.r.l. A process for the preparation of amphoglycinates from vegetable oils and butters and the use thereof
EP1406576B2 (en) 2001-07-18 2011-06-29 Unilever PLC Hair and/or scalp treatment compositions
WO2006053708A1 (en) * 2004-11-22 2006-05-26 Unilever Plc Improved detergent composition
US20150374600A1 (en) * 2009-02-11 2015-12-31 Joseph F. Walsh Methods and preparations that treat human hair loss
DE102010013275A1 (en) * 2010-03-29 2011-09-29 Beiersdorf Ag Microbiologically stable, application-friendly W / O preparations
WO2013025769A3 (en) * 2011-08-15 2014-04-10 The Procter & Gamble Company Methods of enhancing skin hydration and improving non-diseased skin
CN103889394A (en) * 2011-08-15 2014-06-25 宝洁公司 Methods of enhancing skin hydration and improving non-diseased skin
EP2744477B1 (en) 2011-08-15 2018-09-19 The Procter and Gamble Company Methods of enhancing skin hydration and improving non-diseased skin
US10201481B2 (en) 2014-03-07 2019-02-12 The Procter & Gamble Company Personal care compositions and methods of making same
WO2016179446A1 (en) * 2015-05-06 2016-11-10 The Procter & Gamble Company Methods of cosmetically treating skin conditions with a cosmetic personal cleansing composition
CN107530261A (en) * 2015-05-06 2018-01-02 宝洁公司 Utilize the method for cosmetics personal cleaning compositions beauty therapeutic skin disorder
US9901584B2 (en) 2015-05-06 2018-02-27 The Procter & Gamble Company Methods of cosmetically treating skin conditions with a cosmetic personal cleansing composition

Also Published As

Publication number Publication date
FR2685638B1 (en) 1995-04-21

Similar Documents

Publication Publication Date Title
US9499419B2 (en) Methods and compositions for treatment of skin
FR2536277A1 (en) NOVEL ANTI-ACNE COMPOSITION BASED ON BENZOYL PEROXIDE AND AT LEAST ONE OTHER ACTIVE INGREDIENT
JP4176912B2 (en) Cosmetic composition containing moisturizing plant extract
FR2685638A1 (en) Compositions for cosmetic and/or dermatological use, comprising a combination of pyrithione zinc, piroctone olamine and a derivative of collagen and of fatty acid
KR20060049895A (en) Compositions containing anti-acne agents and the use thereof
FR2746316A1 (en) NEW COSMETOLOGICAL OR DERMATOLOGICAL COMPOSITIONS
FR2717079A1 (en) Composition containing a non-photocatalytic metal oxide and tocopherol, its use in the cosmetic and / or dermatological field and methods using it.
EP0904054B1 (en) USE OF alpha-ALKYLGLUCOSIDES AND alpha-ALKYLGLUCOSIDE ESTERS AS ANTI-MICROBIAL EMULSIFYING AGENTS
JP2022180455A (en) Antibacterial composition containing essential oil and antibacterial lipid
JP4560156B2 (en) Cosmetic composition containing moisturizing plant extract
JP2006516022A (en) Scalp treatment
EP0771557B1 (en) Use of ascorbic acid as the active agent for the treatment of seborrhea in a cosmetic and/or dermatalogical composition
FR2585244A1 (en) USE OF LUPINE SOFT SEED POWDER IN CARRYING OUT COSMETIC OR DERMOPHARMACEUTICAL COMPOSITIONS AND COMPOSITIONS OBTAINED
KR19990077322A (en) Compositions Containing Antifungal Agents and Sulfur Compounds
KR20220155304A (en) Personal Care Compositions, Methods of Using Such Compositions and Improving Their Deposition Effects
JP4179971B2 (en) Moisturizing plant extract and external preparation, cosmetic, bath preparation and detergent containing the extract
US10420962B2 (en) Organic hair formulation and treatment
JP4551053B2 (en) Moisturizing plant extract and moisturizing external preparation, cosmetic, bath preparation and detergent composition containing the extract
HU196553B (en) Cosmetic composition for skin-regeneration containing extract of green beans
JP2009256223A (en) Extract liquid from egg of sturgeon
FR2646603A1 (en) CLEANING COMPOSITION
EP0652741B1 (en) Cosmetic or dermatological compositions, particularly shampoos which may be diluted in water without losing viscosity after dilution
JPH11139951A (en) Cosmetic
JP2005089402A (en) External anti-pruritic agent
FR2656523A1 (en) Compositions for cosmetic and/or dermatological use, comprising metal pidolates

Legal Events

Date Code Title Description
ST Notification of lapse