FR2651230B1 - Derives de la 5-amino-1,2,3,4 tetrahydro-acridine et applications comme medicaments. - Google Patents

Derives de la 5-amino-1,2,3,4 tetrahydro-acridine et applications comme medicaments.

Info

Publication number
FR2651230B1
FR2651230B1 FR8911283A FR8911283A FR2651230B1 FR 2651230 B1 FR2651230 B1 FR 2651230B1 FR 8911283 A FR8911283 A FR 8911283A FR 8911283 A FR8911283 A FR 8911283A FR 2651230 B1 FR2651230 B1 FR 2651230B1
Authority
FR
France
Prior art keywords
acridine
tetrahydro
drugs
derivatives
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8911283A
Other languages
English (en)
Other versions
FR2651230A1 (fr
Inventor
Nguyen Dat Xuong
Rapin Jean Robert
Pueyo Jacques
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SYNTHESE RECH
Original Assignee
SYNTHESE RECH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SYNTHESE RECH filed Critical SYNTHESE RECH
Priority to FR8911283A priority Critical patent/FR2651230B1/fr
Priority to CA002064999A priority patent/CA2064999A1/fr
Priority to JP2512400A priority patent/JPH05500055A/ja
Priority to PCT/FR1990/000630 priority patent/WO1991002725A1/fr
Priority to EP90913286A priority patent/EP0487623A1/fr
Publication of FR2651230A1 publication Critical patent/FR2651230A1/fr
Application granted granted Critical
Publication of FR2651230B1 publication Critical patent/FR2651230B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
FR8911283A 1989-08-25 1989-08-25 Derives de la 5-amino-1,2,3,4 tetrahydro-acridine et applications comme medicaments. Expired - Fee Related FR2651230B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR8911283A FR2651230B1 (fr) 1989-08-25 1989-08-25 Derives de la 5-amino-1,2,3,4 tetrahydro-acridine et applications comme medicaments.
CA002064999A CA2064999A1 (fr) 1989-08-25 1990-08-24 Derives de la 5-amino-1,2,3,4 tetrahydro-acridine et utilisation comme medicaments
JP2512400A JPH05500055A (ja) 1989-08-25 1990-08-24 ５―アミノ―１，２，３，４―テトラヒドロアクリジンの誘導体および医薬としての使用
PCT/FR1990/000630 WO1991002725A1 (fr) 1989-08-25 1990-08-24 Derives de la 5-amino-1,2,3,4-tetrahydro-acridine et applications comme medicaments
EP90913286A EP0487623A1 (fr) 1989-08-25 1990-08-24 Derives de la 5-amino-1,2,3,4-tetrahydro-acridine et applications comme medicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8911283A FR2651230B1 (fr) 1989-08-25 1989-08-25 Derives de la 5-amino-1,2,3,4 tetrahydro-acridine et applications comme medicaments.

Publications (2)

Publication Number Publication Date
FR2651230A1 FR2651230A1 (fr) 1991-03-01
FR2651230B1 true FR2651230B1 (fr) 1992-03-13

Family

ID=9384932

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8911283A Expired - Fee Related FR2651230B1 (fr) 1989-08-25 1989-08-25 Derives de la 5-amino-1,2,3,4 tetrahydro-acridine et applications comme medicaments.

Country Status (5)

Country Link
EP (1) EP0487623A1 (fr)
JP (1) JPH05500055A (fr)
CA (1) CA2064999A1 (fr)
FR (1) FR2651230B1 (fr)
WO (1) WO1991002725A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9103752D0 (sv) * 1991-12-18 1991-12-18 Astra Ab New compounds
RU2036198C1 (ru) * 1993-04-01 1995-05-27 Товарищество с ограниченной ответственностью "Полисан" N-МЕТИЛ-N-( α,D -ГЛЮКОПИРАНОЗИЛ) АММОНИЯ-2-(АКРИДОН-9-ОН-10-ИЛ)АЦЕТАТ(ЦИКЛОФЕРОН), ОБЛАДАЮЩИЙ ИНТЕРФЕРОНОГЕННОЙ, ПРОТИВОВИРУСНОЙ, В ТОМ ЧИСЛЕ АНТИВИЧ, АНТИПАРАЗИТАРНОЙ, АНТИПРОМОТОРНОЙ И РАДИОПРОТЕКТИВНОЙ АКТИВНОСТЬЮ
PL207853B1 (pl) * 2000-04-04 2011-02-28 Fundacja Rozwoju Diagnostyki I Terapii Nowe (1-adamantyloamino)pirydyny, sposób ich wytwarzania i zastosowanie medyczne
DE10132726A1 (de) * 2001-07-05 2003-02-27 Gruenenthal Gmbh Verwendung von substituierten gamma-Lactonverbindungen als Arzneimittel
GB0223494D0 (en) * 2002-10-09 2002-11-13 Neuropharma Sa Dual binding site acetylcholinesterase inhibitors for the treatment of alzheimer's disease
GB0316094D0 (en) 2003-07-09 2003-08-13 Neuropharma Sa Acetylcholinesterase dual inhibitors
WO2012154879A2 (fr) * 2011-05-09 2012-11-15 Van Andel Research Institute Inhibiteurs d'autophagie
CN105330646B (zh) * 2015-12-04 2019-05-24 上海勋和医药科技有限公司 一种抗肿瘤药马来酸来那替尼的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3860M (fr) * 1962-12-21 1966-01-24 Madan Ag Acides halogénophénoxyacétiques et leurs sels.
US4816456A (en) * 1986-10-01 1989-03-28 Summers William K Administration of monoamine acridines in cholinergic neuronal deficit states
EP0319429B1 (fr) * 1987-12-03 1994-04-27 Mitsubishi Kasei Corporation Dérivés de la 9-(acylamino)tétrahydroacridine et agents pour l'amélioration de la mémoire les contenant comme ingrédient

Also Published As

Publication number Publication date
WO1991002725A1 (fr) 1991-06-07
CA2064999A1 (fr) 1991-02-26
EP0487623A1 (fr) 1992-06-03
JPH05500055A (ja) 1993-01-14
FR2651230A1 (fr) 1991-03-01

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Legal Events

Date Code Title Description
GC Lien (pledge) constituted
ST Notification of lapse