FR2649617B1 - - Google Patents

Info

Publication number
FR2649617B1
FR2649617B1 FR8909391A FR8909391A FR2649617B1 FR 2649617 B1 FR2649617 B1 FR 2649617B1 FR 8909391 A FR8909391 A FR 8909391A FR 8909391 A FR8909391 A FR 8909391A FR 2649617 B1 FR2649617 B1 FR 2649617B1
Authority
FR
France
Prior art keywords
chamber
pct
active principle
electrolyte
volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8909391A
Other languages
French (fr)
Other versions
FR2649617A1 (en
Inventor
Tafani Jean-Pierre
Valter Francis
Zeghal Slim
Alexandre Jean
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VEPROL
Original Assignee
VEPROL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8909391A priority Critical patent/FR2649617A1/en
Application filed by VEPROL filed Critical VEPROL
Priority to US07/659,409 priority patent/US5135499A/en
Priority to AT90910755T priority patent/ATE117567T1/en
Priority to PCT/FR1990/000526 priority patent/WO1991000753A1/en
Priority to DK90910755.9T priority patent/DK0433429T3/en
Priority to ES90910755T priority patent/ES2071105T3/en
Priority to DE69016387T priority patent/DE69016387T2/en
Priority to EP90910755A priority patent/EP0433429B1/en
Publication of FR2649617A1 publication Critical patent/FR2649617A1/en
Application granted granted Critical
Publication of FR2649617B1 publication Critical patent/FR2649617B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16N—LUBRICATING
    • F16N11/00—Arrangements for supplying grease from a stationary reservoir or the equivalent in or on the machine or member to be lubricated; Grease cups
    • F16N11/10—Arrangements for supplying grease from a stationary reservoir or the equivalent in or on the machine or member to be lubricated; Grease cups by pressure of another fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Medicinal Preparation (AREA)

Abstract

PCT No. PCT/FR90/00526 Sec. 371 Date Mar. 11, 1991 Sec. 102(e) Date Mar. 11, 1991 PCT Filed Jul. 12, 1990 PCT Pub. No. WO91/00753 PCT Pub. Date Jan. 24, 1991.The device includes an electrolysis cell (C) comprising: a closed variable volume first chamber (2) containing an electrolyte that gives off gas under the effect of an electrolysis voltage applied to electrodes (3, 4) in contact with the electrolyte, the gas given off causing the first chamber to expand; and a variable volume second chamber (7) containing the active principle, said second chamber opening out to the outside via an orifice (11) enabling the active principle to be delivered; the total volume of the two chambers (2, 7) being constant, such that expansion of the first chamber causes the volume of the second chamber to be reduced and gives rise to a corresponding controlled expulsion of the active principle contained therein. According to the invention, the two chambers (2, 7) are separated from each other by a flexible wall (6) uniformly subjected to the pressure resulting from gas being given off in such a manner as to reduce the volume of the second chamber (7) and expel the active principle; and the first chamber (2) contains a liquid electrolyte in which the electrodes (3, 4) that extend over the major portion of the length of said first chamber are immersed so that the electrodes are always at least in part in contact with the electrolyte regardless of the position of the device.
FR8909391A 1989-07-12 1989-07-12 DEVICE FOR DELIVERING A PHARMACOLOGICAL ACTIVE PRINCIPLE BY ELECTROLYTIC PUMPING Granted FR2649617A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR8909391A FR2649617A1 (en) 1989-07-12 1989-07-12 DEVICE FOR DELIVERING A PHARMACOLOGICAL ACTIVE PRINCIPLE BY ELECTROLYTIC PUMPING
AT90910755T ATE117567T1 (en) 1989-07-12 1990-07-12 DEVICE FOR DELIVERING AN ACTIVE PHARMACEUTICAL PRINCIPLE BY ELECTROLYTIC PUMping.
PCT/FR1990/000526 WO1991000753A1 (en) 1989-07-12 1990-07-12 Device for releasing a pharmacologically active principle by electrolytic pumping
DK90910755.9T DK0433429T3 (en) 1989-07-12 1990-07-12 System for releasing an active pharmacological principle by electrolytic pumping
US07/659,409 US5135499A (en) 1989-07-12 1990-07-12 Device for delivering a pharmacologically active principle by electrolytic pumping
ES90910755T ES2071105T3 (en) 1989-07-12 1990-07-12 DEVICE FOR EJECTION OF A PHARMACOLOGICAL PRINCIPLE BY ELECTROLYTIC PUMPING.
DE69016387T DE69016387T2 (en) 1989-07-12 1990-07-12 DEVICE FOR DELIVERING AN ACTIVE PHARMACEUTICAL PRINCIPLE BY ELECTROLYTIC PUMPING.
EP90910755A EP0433429B1 (en) 1989-07-12 1990-07-12 Device for releasing a pharmacologically active principle by electrolytic pumping

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8909391A FR2649617A1 (en) 1989-07-12 1989-07-12 DEVICE FOR DELIVERING A PHARMACOLOGICAL ACTIVE PRINCIPLE BY ELECTROLYTIC PUMPING

Publications (2)

Publication Number Publication Date
FR2649617A1 FR2649617A1 (en) 1991-01-18
FR2649617B1 true FR2649617B1 (en) 1994-07-13

Family

ID=9383724

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8909391A Granted FR2649617A1 (en) 1989-07-12 1989-07-12 DEVICE FOR DELIVERING A PHARMACOLOGICAL ACTIVE PRINCIPLE BY ELECTROLYTIC PUMPING

Country Status (8)

Country Link
US (1) US5135499A (en)
EP (1) EP0433429B1 (en)
AT (1) ATE117567T1 (en)
DE (1) DE69016387T2 (en)
DK (1) DK0433429T3 (en)
ES (1) ES2071105T3 (en)
FR (1) FR2649617A1 (en)
WO (1) WO1991000753A1 (en)

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US5527288A (en) * 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
DK0746356T3 (en) * 1991-10-24 2000-10-02 Macromed Inc Gas powered device for administering drugs
EP0563501A1 (en) * 1992-04-01 1993-10-06 SULZER Medizinaltechnik AG Device for the metered supply of a liquid and use of the device
AU4058993A (en) * 1992-06-15 1994-01-04 Max Wyssmann Device for the intentional and controllable distribution of a liquid or visquous material
US5318557A (en) * 1992-07-13 1994-06-07 Elan Medical Technologies Limited Medication administering device
US5348539A (en) * 1993-06-29 1994-09-20 Glenn Herskowitz Infusion pump for use with prepackaged IV bags
WO1995013760A1 (en) * 1993-11-15 1995-05-26 Commonwealth Scientific And Industrial Research Organisation Gas driven controlled release device
US5997501A (en) * 1993-11-18 1999-12-07 Elan Corporation, Plc Intradermal drug delivery device
US5505708A (en) * 1994-04-18 1996-04-09 Atkinson; Carey J. System for delivery of intravenous fluids and the like and the method of making thereof
IE70735B1 (en) * 1994-08-15 1996-12-11 Elan Med Tech Orally administrable delivery device
US6117455A (en) * 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent
IE77523B1 (en) * 1995-09-11 1997-12-17 Elan Med Tech Medicament delivery device
ZA9610374B (en) * 1995-12-11 1997-06-23 Elan Med Tech Cartridge-based drug delivery device
KR100189152B1 (en) * 1996-05-06 1999-06-01 양윤종 Automatic supplying method and system with micom
US5785688A (en) * 1996-05-07 1998-07-28 Ceramatec, Inc. Fluid delivery apparatus and method
DK0973499T3 (en) * 1997-03-31 2003-11-17 Alza Corp Implantable diffusion delivery system
US6450991B1 (en) * 1997-12-05 2002-09-17 Interag Delivery devices and their use
US5954696A (en) * 1997-12-15 1999-09-21 B. Braun Medical, Inc. Pressure infusion pump
US5957895A (en) 1998-02-20 1999-09-28 Becton Dickinson And Company Low-profile automatic injection device with self-emptying reservoir
US6210368B1 (en) 1998-04-30 2001-04-03 Medtronic, Inc. Reservoir volume sensors
NZ331391A (en) * 1998-08-14 2000-12-22 Dec Res Dispensing apparatus comprising a formulation, a pair of electrodes and a housing means for agent and electrodes
US6458102B1 (en) * 1999-05-28 2002-10-01 Medtronic Minimed, Inc. External gas powered programmable infusion device
US6572740B2 (en) 2000-04-13 2003-06-03 Elan Pharma International Limited Electrolytic cell
SG106631A1 (en) * 2001-08-31 2004-10-29 Agency Science Tech & Res Liquid delivering device
WO2005044342A1 (en) * 2003-11-07 2005-05-19 Agency For Science, Technology And Research Liquid housing chamber and liquid delivering device containing such chamber
US8246569B1 (en) 2004-08-17 2012-08-21 California Institute Of Technology Implantable intraocular pressure drain
US20060258994A1 (en) * 2005-05-12 2006-11-16 Avery Robert L Implantable delivery device for administering pharmacological agents to an internal portion of a body
CA2833354C (en) * 2006-03-14 2015-12-15 University Of Southern California Mems device and method for delivery of therapeutic agents
JP5542691B2 (en) 2007-12-20 2014-07-09 ユニバーシティ オブ サザン カリフォルニア Devices and methods for delivering therapeutic agents
MX2010007382A (en) 2008-01-03 2010-12-20 Univ Southern California Implantable drug-delivery devices, and apparatus and methods for refilling the devices.
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
EP2323716B1 (en) 2008-05-08 2015-03-04 MiniPumps, LLC Drug-delivery pumps
CN102202706A (en) * 2008-05-08 2011-09-28 迷你泵有限责任公司 Implantable drug-delivery devices, and apparatus and methods for filling the devices
EP2898911A1 (en) * 2008-05-08 2015-07-29 MiniPumps, LLC Implantable pumps and cannulas therefor
US9849238B2 (en) 2008-05-08 2017-12-26 Minipumps, Llc Drug-delivery pump with intelligent control
US8506529B1 (en) * 2008-07-08 2013-08-13 MCube Inc. Method and structure of monolithetically integrated microneedle biochip
US9595479B2 (en) 2008-07-08 2017-03-14 MCube Inc. Method and structure of three dimensional CMOS transistors with hybrid crystal orientations
US20100075481A1 (en) 2008-07-08 2010-03-25 Xiao (Charles) Yang Method and structure of monolithically integrated ic-mems oscillator using ic foundry-compatible processes
US8148781B2 (en) 2008-07-28 2012-04-03 MCube Inc. Method and structures of monolithically integrated ESD suppression device
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
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US9222819B2 (en) 2009-02-20 2015-12-29 University Of Southern California Tracking and controlling fluid delivery from chamber
US8372046B2 (en) * 2009-02-20 2013-02-12 University Of Southern California Drug delivery device with in-plane bandpass regulation check valve in heat-shrink packaging
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US9250106B2 (en) 2009-02-27 2016-02-02 Tandem Diabetes Care, Inc. Methods and devices for determination of flow reservoir volume
EP3284494A1 (en) 2009-07-30 2018-02-21 Tandem Diabetes Care, Inc. Portable infusion pump system
AU2010284216B2 (en) * 2009-08-18 2015-10-15 Minipumps, Llc Electrolytic drug-delivery pump with adaptive control
US8882748B2 (en) * 2009-10-08 2014-11-11 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including chemical permeation enhancers
US9014799B2 (en) * 2009-10-08 2015-04-21 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including electrically-actuated permeation enhancement
US9017310B2 (en) * 2009-10-08 2015-04-28 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including microneedles
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US9005108B2 (en) 2012-09-27 2015-04-14 Palo Alto Research Center Incorporated Multiple reservoir drug delivery device and methods
US9999720B2 (en) 2012-09-27 2018-06-19 Palo Alto Research Center Incorporated Drug reconstitution and delivery device and methods
US9744341B2 (en) 2013-01-15 2017-08-29 Palo Alto Research Center Incorporated Devices and methods for intraluminal retention and drug delivery
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US9297083B2 (en) 2013-12-16 2016-03-29 Palo Alto Research Center Incorporated Electrolytic gas generating devices, actuators, and methods
JP6385740B2 (en) * 2014-07-04 2018-09-05 ルネサスエレクトロニクス株式会社 Electronic device and manufacturing method thereof
US10278675B2 (en) 2014-07-31 2019-05-07 Palo Alto Research Center Incorporated Implantable estrus detection devices, systems, and methods
US9801660B2 (en) 2014-07-31 2017-10-31 Palo Alto Research Center Incorporated Implantable fluid delivery devices, systems, and methods
US10492141B2 (en) 2015-11-17 2019-11-26 Tandem Diabetes Care, Inc. Methods for reduction of battery usage in ambulatory infusion pumps

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US3895538A (en) * 1974-11-22 1975-07-22 Donald T Mcgregor Slack compensator for brake systems
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US4886514A (en) * 1985-05-02 1989-12-12 Ivac Corporation Electrochemically driven drug dispenser

Also Published As

Publication number Publication date
US5135499A (en) 1992-08-04
DK0433429T3 (en) 1995-06-26
ES2071105T3 (en) 1995-06-16
EP0433429A1 (en) 1991-06-26
DE69016387D1 (en) 1995-03-09
DE69016387T2 (en) 1995-09-21
EP0433429B1 (en) 1995-01-25
ATE117567T1 (en) 1995-02-15
WO1991000753A1 (en) 1991-01-24
FR2649617A1 (en) 1991-01-18

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Legal Events

Date Code Title Description
TP Transmission of property
GC Lien (pledge) constituted
ST Notification of lapse