FR2645864B1 - Nouveaux derives alcoyles en 17/21 de la 19-nor progesterone, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant - Google Patents

Nouveaux derives alcoyles en 17/21 de la 19-nor progesterone, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant

Info

Publication number
FR2645864B1
FR2645864B1 FR8904910A FR8904910A FR2645864B1 FR 2645864 B1 FR2645864 B1 FR 2645864B1 FR 8904910 A FR8904910 A FR 8904910A FR 8904910 A FR8904910 A FR 8904910A FR 2645864 B1 FR2645864 B1 FR 2645864B1
Authority
FR
France
Prior art keywords
same
progesterone
novel
processes
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8904910A
Other languages
English (en)
Other versions
FR2645864A1 (fr
Inventor
Claude Tchernatinsky
Nejib Mohamed Nasraoui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Theramex SAM
Original Assignee
Laboratoire Theramex SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8904910A priority Critical patent/FR2645864B1/fr
Application filed by Laboratoire Theramex SAM filed Critical Laboratoire Theramex SAM
Priority to TNTNSN90053A priority patent/TNSN90053A1/fr
Priority to KR1019900702623A priority patent/KR920700219A/ko
Priority to AU55525/90A priority patent/AU635739B2/en
Priority to EP90907142A priority patent/EP0437552A1/fr
Priority to PCT/FR1990/000270 priority patent/WO1990012027A1/fr
Priority to HU904373A priority patent/HU208152B/hu
Priority to JP2506960A priority patent/JPH04500523A/ja
Publication of FR2645864A1 publication Critical patent/FR2645864A1/fr
Priority to NO905344A priority patent/NO174393C/no
Priority to FI906116A priority patent/FI906116A0/fi
Priority to SU904894526A priority patent/RU1836379C/ru
Priority to OA59916A priority patent/OA09632A/fr
Application granted granted Critical
Publication of FR2645864B1 publication Critical patent/FR2645864B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8904910A 1989-04-13 1989-04-13 Nouveaux derives alcoyles en 17/21 de la 19-nor progesterone, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant Expired - Fee Related FR2645864B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR8904910A FR2645864B1 (fr) 1989-04-13 1989-04-13 Nouveaux derives alcoyles en 17/21 de la 19-nor progesterone, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
JP2506960A JPH04500523A (ja) 1989-04-13 1990-04-13 １９―ノルプロゲステロンの新規の１７／２１アルキル化誘導体、それらの製造方法及びそれらを含有する薬剤組成物
AU55525/90A AU635739B2 (en) 1989-04-13 1990-04-13 Alkyl derivates in 17/21 of 19-nor progesterone
EP90907142A EP0437552A1 (fr) 1989-04-13 1990-04-13 Derives alcoyles en 17/21 de la 19-nor progesterone
PCT/FR1990/000270 WO1990012027A1 (fr) 1989-04-13 1990-04-13 Derives alcoyles en 17/21 de la 19-nor progesterone
HU904373A HU208152B (en) 1989-04-13 1990-04-13 Process for producing 19-norprogesterone derivatives alkylated in 17/21-position and pharmaceutical compositions comprising such compounds
TNTNSN90053A TNSN90053A1 (fr) 1989-04-13 1990-04-13 Procede d'obtention de nouveaux derives alcoyles en 17/21 de la 19- nor progesterone
KR1019900702623A KR920700219A (ko) 1989-04-13 1990-04-13 19-노르 프로게스테론의 17 / 21 알킬화된 유도체, 그의 제법 및 이들을 함유하는 약제 조성물
NO905344A NO174393C (no) 1989-04-13 1990-12-11 Analogifremgangsmåte for fremstilling av terapeutisk aktive 6-metyl-19-nor-pregna-4,6-diener som er 17 eventuelt 21-alkylert
FI906116A FI906116A0 (fi) 1989-04-13 1990-12-12 17/21-alkylerade 19-norprogesteronderivat.
SU904894526A RU1836379C (ru) 1989-04-13 1990-12-12 Способ получени 17- @ -алкилированных 6-метил-19-норпрегна-4,6-диенов и промежуточные соединени этого синтеза
OA59916A OA09632A (fr) 1989-04-13 1990-12-13 Nouveaux derives alcoyles en 17/21 de la 19-nor progesterone leurs procedes d'obtention et les compositions pharmaceutiques en renfermant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8904910A FR2645864B1 (fr) 1989-04-13 1989-04-13 Nouveaux derives alcoyles en 17/21 de la 19-nor progesterone, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant

Publications (2)

Publication Number Publication Date
FR2645864A1 FR2645864A1 (fr) 1990-10-19
FR2645864B1 true FR2645864B1 (fr) 1991-07-12

Family

ID=9380699

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8904910A Expired - Fee Related FR2645864B1 (fr) 1989-04-13 1989-04-13 Nouveaux derives alcoyles en 17/21 de la 19-nor progesterone, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant

Country Status (12)

Country Link
EP (1) EP0437552A1 (fr)
JP (1) JPH04500523A (fr)
KR (1) KR920700219A (fr)
AU (1) AU635739B2 (fr)
FI (1) FI906116A0 (fr)
FR (1) FR2645864B1 (fr)
HU (1) HU208152B (fr)
NO (1) NO174393C (fr)
OA (1) OA09632A (fr)
RU (1) RU1836379C (fr)
TN (1) TNSN90053A1 (fr)
WO (1) WO1990012027A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2675047B1 (fr) * 1991-04-09 1995-05-12 Theramex Nouvelles compositions pharmaceutiques anti-glaucomateuses et leur procede d'obtention.
ES2139602T3 (es) * 1991-06-18 2000-02-16 Theramex Composiciones oculares que contienen esteroides y su utilizacion para el tratamiento del glaucoma.
FR2679236B1 (fr) * 1991-07-18 1997-01-24 Theramex Nouveaux sterouides substitues en position 6, leurs procedes d'obtention et des compositions pharmaceutiques en renfermant.
HU231125B1 (hu) * 2016-12-16 2020-12-28 Richter Gedeon Nyrt. Ipari eljárás Nomegesztrol-acetát előállítására

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361744A (en) * 1962-07-18 1968-01-02 American Cyanamid Co Novel 17-hydrocarbon substituted progesterones, intermediates and methods of preparing the same
FR2077877B1 (fr) * 1970-02-20 1974-02-01 Roussel Uclaf
FR2552766B1 (fr) * 1983-10-04 1987-06-26 Theramex Nouveau procede de preparation de derives de la serie du 17 a-hydroxy 19-nor progesterone
AU624096B2 (en) * 1987-10-27 1992-06-04 Laboratoire Theramex S.A. Derivatives of 19-norprogesterone, their preparation and their use

Also Published As

Publication number Publication date
AU635739B2 (en) 1993-04-01
OA09632A (fr) 1993-04-30
NO174393C (no) 1994-04-27
RU1836379C (ru) 1993-08-23
NO174393B (no) 1994-01-17
HU904373D0 (en) 1991-06-28
NO905344L (no) 1991-02-01
NO905344D0 (no) 1990-12-11
AU5552590A (en) 1990-11-05
HU208152B (en) 1993-08-30
JPH04500523A (ja) 1992-01-30
FR2645864A1 (fr) 1990-10-19
TNSN90053A1 (fr) 1991-03-05
WO1990012027A1 (fr) 1990-10-18
KR920700219A (ko) 1992-02-19
EP0437552A1 (fr) 1991-07-24
HUT56579A (en) 1991-09-30
FI906116A0 (fi) 1990-12-12

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Legal Events

Date Code Title Description
ST Notification of lapse