FR2615853B1 - Nouveau procede pour la preparation de derives de la piperazine pharmacologiquement actifs, derives et nouveaux intermediaires obtenus - Google Patents

Nouveau procede pour la preparation de derives de la piperazine pharmacologiquement actifs, derives et nouveaux intermediaires obtenus

Info

Publication number
FR2615853B1
FR2615853B1 FR888802286A FR8802286A FR2615853B1 FR 2615853 B1 FR2615853 B1 FR 2615853B1 FR 888802286 A FR888802286 A FR 888802286A FR 8802286 A FR8802286 A FR 8802286A FR 2615853 B1 FR2615853 B1 FR 2615853B1
Authority
FR
France
Prior art keywords
derivatives
preparation
pharmacologically active
novel process
new intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR888802286A
Other languages
English (en)
Other versions
FR2615853A1 (fr
Inventor
Zoltan Budai
Livia Gregor-Nee-Boros
Tibor Mezei
Klara Reiter-Nee-Esses
Eva Judit Tajthy-Nee-Juhasz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU71887A external-priority patent/HU198477B/hu
Priority claimed from HU71787A external-priority patent/HU198204B/hu
Priority claimed from HU71687A external-priority patent/HU197313B/hu
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FR2615853A1 publication Critical patent/FR2615853A1/fr
Application granted granted Critical
Publication of FR2615853B1 publication Critical patent/FR2615853B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR888802286A 1987-02-25 1988-02-25 Nouveau procede pour la preparation de derives de la piperazine pharmacologiquement actifs, derives et nouveaux intermediaires obtenus Expired - Lifetime FR2615853B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU71887A HU198477B (en) 1987-02-25 1987-02-25 Process for producing pyrimidinyl piperazine derivatives
HU71787A HU198204B (en) 1987-02-25 1987-02-25 Process for production of derivatives of piperasine
HU71687A HU197313B (en) 1987-02-25 1987-02-25 Process for producing 8-azaspiro <4.5> decane-7,9-dione-8-propine-/2/

Publications (2)

Publication Number Publication Date
FR2615853A1 FR2615853A1 (fr) 1988-12-02
FR2615853B1 true FR2615853B1 (fr) 1991-01-04

Family

ID=27269942

Family Applications (1)

Application Number Title Priority Date Filing Date
FR888802286A Expired - Lifetime FR2615853B1 (fr) 1987-02-25 1988-02-25 Nouveau procede pour la preparation de derives de la piperazine pharmacologiquement actifs, derives et nouveaux intermediaires obtenus

Country Status (20)

Country Link
KR (1) KR880009955A (fr)
CN (1) CN88100923A (fr)
AT (1) AT395851B (fr)
BE (1) BE1001464A3 (fr)
CA (1) CA1300141C (fr)
CH (1) CH677924A5 (fr)
CS (1) CS274423B2 (fr)
DE (1) DE3806009C2 (fr)
DK (1) DK99388A (fr)
ES (1) ES2009236A6 (fr)
FI (1) FI880895A (fr)
FR (1) FR2615853B1 (fr)
GB (1) GB2201417B (fr)
GR (1) GR1002245B (fr)
IL (1) IL85545A (fr)
IT (1) IT1217342B (fr)
NL (1) NL8800484A (fr)
PL (1) PL152958B1 (fr)
SE (1) SE8800651L (fr)
YU (1) YU46441B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU217129B (hu) * 1993-07-16 1999-11-29 EGIS Gyógyszergyár Rt. Eljárás nagy tisztaságú buspiron gyógyászati hatóanyag előállítására
KR950014099A (ko) * 1993-11-10 1995-06-15 장기하 N-(2-피리미딜)피페라지닐 부틸아미드의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545543B1 (de) * 1964-07-03 1970-01-22 Astra Apotekarnes Kem Fab 4-Aminobutinylimide,ihre Salze und Verfahren zu deren Herstellung
SE300422B (fr) * 1964-07-03 1968-04-29 Astra Ab
US3354178A (en) * 1965-04-09 1967-11-21 Sterling Drug Inc Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
JPS6310760A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd イミド誘導体の新規製造法
JPS6310786A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd 新規イミド誘導体およびその製造法

Also Published As

Publication number Publication date
SE8800651L (sv) 1988-08-26
AT395851B (de) 1993-03-25
DK99388D0 (da) 1988-02-25
PL270815A1 (en) 1989-04-03
PL152958B1 (en) 1991-02-28
YU46441B (sh) 1993-10-20
IT1217342B (it) 1990-03-22
CS274423B2 (en) 1991-04-11
CS122288A2 (en) 1990-08-14
BE1001464A3 (fr) 1989-11-07
DK99388A (da) 1988-08-26
ES2009236A6 (es) 1989-09-16
CH677924A5 (fr) 1991-07-15
CA1300141C (fr) 1992-05-05
YU36288A (en) 1989-10-31
SE8800651D0 (sv) 1988-02-25
GB2201417B (en) 1990-10-31
FI880895A (fi) 1988-08-26
IL85545A (en) 1992-05-25
IL85545A0 (en) 1988-08-31
FI880895A0 (fi) 1988-02-25
DE3806009A1 (de) 1988-09-08
GB8804385D0 (en) 1988-03-23
DE3806009C2 (de) 1996-09-12
FR2615853A1 (fr) 1988-12-02
GR1002245B (en) 1996-04-22
KR880009955A (ko) 1988-10-06
NL8800484A (nl) 1988-09-16
GB2201417A (en) 1988-09-01
ATA47688A (de) 1992-08-15
IT8819545A0 (it) 1988-02-25
CN88100923A (zh) 1988-09-28
GR880100108A (el) 1988-12-16

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20051031