FR2601930A1 - Package constituted by a closed envelope containing a dose of an active substance - Google Patents

Package constituted by a closed envelope containing a dose of an active substance Download PDF

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Publication number
FR2601930A1
FR2601930A1 FR8610795A FR8610795A FR2601930A1 FR 2601930 A1 FR2601930 A1 FR 2601930A1 FR 8610795 A FR8610795 A FR 8610795A FR 8610795 A FR8610795 A FR 8610795A FR 2601930 A1 FR2601930 A1 FR 2601930A1
Authority
FR
France
Prior art keywords
biodegradable material
packaging according
dose
envelope
active substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR8610795A
Other languages
French (fr)
Inventor
Guy Breger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BREGER AINE ETS
Original Assignee
BREGER AINE ETS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BREGER AINE ETS filed Critical BREGER AINE ETS
Priority to FR8610795A priority Critical patent/FR2601930A1/en
Publication of FR2601930A1 publication Critical patent/FR2601930A1/en
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D65/00—Wrappers or flexible covers; Packaging materials of special type or form
    • B65D65/38—Packaging materials of special type or form
    • B65D65/46—Applications of disintegrable, dissolvable or edible materials
    • B65D65/466—Bio- or photodegradable packaging materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D65/00—Wrappers or flexible covers; Packaging materials of special type or form
    • B65D65/38—Packaging materials of special type or form
    • B65D65/46—Applications of disintegrable, dissolvable or edible materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W90/00—Enabling technologies or technologies with a potential or indirect contribution to greenhouse gas [GHG] emissions mitigation
    • Y02W90/10—Bio-packaging, e.g. packing containers made from renewable resources or bio-plastics

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

a. The invention relates to a capsule constituted by a closed envelope containing a dose of a liquid or powdery active substance in a particular field, pharmacy in particular. b. Package characterised in that the envelope is made from a film of biodegradable material which is soluble in water and which can be ingested by humans or by animals.

Description

"Emballage constitué par une enveloppe fermée renfermant
une dose d'une substance active."Package consisting of a closed envelope containing
a dose of an active substance.

L'invention se rapporte à un emballage constitué par une enveloppe fermée contenant une dose d'une substance active dans un domaine particulier, notamment en pharmacie. The invention relates to a packaging consisting of a closed envelope containing a dose of an active substance in a particular field, in particular in pharmacy.

Depuis plusieurs années, on trouve dans le commerce des emballages unitaires en matériau synthétique ou papier plus ou moins rigide contenant des produits alimentaires ou pharmaceutiques. For several years, unitary packaging made of more or less rigid synthetic or paper material has been found on the market, containing food or pharmaceutical products.

Pour utiliser leur contenu, il est nécessaire de déchirer ces emballages manuellement ou à l'aide de ciseaux s'ils sont trop résistants. To use their contents, it is necessary to tear these packages manually or with scissors if they are too strong.

En plus de son caractère parfois très incommode, cette opération présente l'inconvénient d'enraciner obligatoirement la perte d'un pourcentage non négligeable du contenu de l'emballage qui adhère à ses parois ou reste coincé dans ses replis. Cet inconvénient est particulièrement grave dans le cas de produits pharmaceutiques pour lesquels des posologies très strictes doivent être respectées. In addition to its sometimes very inconvenient nature, this operation has the drawback of necessarily rooting the loss of a non-negligible percentage of the contents of the packaging which adheres to its walls or remains trapped in its folds. This drawback is particularly serious in the case of pharmaceutical products for which very strict dosages must be observed.

Un autre inconvénient inhérent aux emballages susmentionnés est lié au fait que les matériaux utilisés ne sont souvent destructibles que par incinération, et que leur combustion provoque fréquemment des émanations toxiques. Another drawback inherent in the aforementioned packaging is related to the fact that the materials used are often destructible only by incineration, and that their combustion frequently causes toxic fumes.

La présente invention a pour objet de remédier à ces inconvénients en proposant un emballage du type ci-dessus permettant, dans tous les cas, de garantir le respect des doses prescrites et dont la destruction ne présente aucun danger pour l'environnement. The object of the present invention is to remedy these drawbacks by proposing packaging of the above type making it possible, in all cases, to guarantee compliance with the prescribed doses and the destruction of which does not present any danger to the environment.

A cet effet, l'invention concerne un emballage du type ci-dessus, caractérisé en ce que l'enveloppe est réalisée à partir d'un film en un matériau biodégradable soluble dans l'eau et pouvant être ingéré par l'homme ou l'animal. To this end, the invention relates to a packaging of the above type, characterized in that the envelope is produced from a film of a biodegradable material soluble in water and capable of being ingested by man or 'animal.

Pour utiliser un tel emballage, il n'est plus nécessaire de faire un effort pour ouvrir l'enveloppe puisque le contenant et le contenu se plongent dans l'eau pour former une solution buvable en l'état et parfaitement acceptée par l'organisme. To use such packaging, it is no longer necessary to make an effort to open the envelope since the container and the contents are immersed in water to form a drinkable solution in the state and perfectly accepted by the body.

n plus de cet avantage, l'utilisation de l'emballage conforme à l'invention permet également de garantir l'absorption de la totalité de la dose prescrite ; en effet, la solution formée est ingérée dans sa totalité sans risquer qu'une partie ne reste retenue dans les replis de l'enveloppe. n in addition to this advantage, the use of the packaging in accordance with the invention also makes it possible to guarantee the absorption of the entire prescribed dose; in fact, the solution formed is ingested in its entirety without risking that part remains retained in the folds of the envelope.

Pour certaines utilisations particulières et selon une autre caractéristique de l'invention, il peut être intéressant que le matériau biodégradable ne soit soluble qu'a' partir d'une température de seuil prédéterminée ; dans ce cas, il est nécessaire de chauffer un peu l'eau contenant l'emballage pour obtenir sa dissolution. For certain particular uses and according to another characteristic of the invention, it may be advantageous for the biodegradable material to be soluble only from a predetermined threshold temperature; in this case, it is necessary to heat the water containing the packaging a little to obtain its dissolution.

Conformément à l'invention, le matériau biodégradable peut être choisi parmi de nombreux composants ingérables connus ; ce choix est en fait conditionné par les propriétés finales souhaitées pour l'emballage. According to the invention, the biodegradable material can be chosen from many known ingestible components; this choice is in fact conditioned by the final properties desired for the packaging.

A titre d'exemple, l'utilisation de gélatine du grade judicieusement adapté permet d'obtenir une solubilité en fonction de la température ou du PH. By way of example, the use of gelatin of the judiciously adapted grade makes it possible to obtain a solubility as a function of temperature or of pH.

Bien entendu, l'invention n'est pas limitée à l'utilisation de gélatine, et le matériau biodégradable peut être totalement différent, par exemple renfermer de l'alcool polyvinylique.  Of course, the invention is not limited to the use of gelatin, and the biodegradable material can be completely different, for example containing polyvinyl alcohol.

Par ailleurs, selon une autre caractéristique de l'invention, le matériau biodégradable contient des adjuvants susceptibles de modifier ses propriétés physiques ou chimiques ; parmi ces adjuvants, on peut, par exemple, citer le glycérol. Furthermore, according to another characteristic of the invention, the biodegradable material contains adjuvants capable of modifying its physical or chemical properties; among these adjuvants, mention may, for example, be made of glycerol.

Selon une autre caractéristique de l'invention, le matériau biodégradable est thermosoudable ou collable à l'eau. According to another characteristic of the invention, the biodegradable material is heat-sealable or bondable with water.

I1 s'agit là d'une caractéristique importante de l'invention, facilitant, dans une large mesure, la fabrication de l'emballage à partir d'un film en matériau biodégradable. This is an important characteristic of the invention, facilitating, to a large extent, the manufacture of the packaging from a film of biodegradable material.

Comme il a déjà été indiqué, le choix du matériau biodégradable conditionne, d'une part, la vitesse de solubilité de l'enveloppe et, d'autre part, les propriétés physiques de celle-ci. Par un choix approprié, il est, par exemple, possible d'obtenir une enveloppe transparente, permettant de visionner la substance active, ou une enveloppe opaque de nature à la protéger de la lumière. De même, il est possible d'utiliser un matériau pouvant être marqué ou imprimé pour permettre l'identification de son contenu. As already indicated, the choice of biodegradable material conditions, on the one hand, the speed of solubility of the envelope and, on the other hand, the physical properties thereof. By an appropriate choice, it is, for example, possible to obtain a transparent envelope, making it possible to view the active substance, or an opaque envelope capable of protecting it from light. Similarly, it is possible to use a material that can be marked or printed to allow the identification of its content.

Dans tous les cas, l'enveloppe en matériau biodégradable constitue une barrière de protection pour la substance active ; celle-ci doit toutefois être elle-même protégée des agents contaminants pour demeurer ingérable. In all cases, the envelope of biodegradable material constitutes a protective barrier for the active substance; however, it must itself be protected from contaminating agents to remain unmanageable.

Les caractéristiques de l'emballage, objet de l'invention, seront décrites plus en détail grâce aux exemples ci-aprrès
Exemple 1 : Utilisation en agriculture.The characteristics of the packaging which is the subject of the invention will be described in more detail by means of the examples below.
Example 1: Use in agriculture.

I1 est connu que les plantations sont régulièrement endommagées par des organismes destructeurs pendant la saison des pluies. Pour remédier à cet état de fait, on a pensé à utiliser des prédateurs de ces organismes ; cependant, pour etre efficaces, ceux-ci doivent être présents sur les plantations dès le début de la multiplication des parasites (période des pluies), ce qui est difficilement réalisable en pratique, étant donné que les terrains sont peu accessibles pendant la saison des pluies. It is known that plantations are regularly damaged by destructive organisms during the rainy season. To remedy this state of affairs, thought has been given to using predators from these organisms; however, to be effective, these must be present on the plantations from the start of the multiplication of parasites (rainy period), which is difficult to achieve in practice, since the land is not very accessible during the rainy season. .

Pour remédier à cet inconvénient, il est possible d'utiliser un emballage selon l'invention constitué par une enveloppe en un matériau biodégradable contenant en tant que substance active, des micro-organismes phytosanitaires susceptibles de détruire les parasites considérés. Lors de la période des pluies, l'enveloppe se dissout automatiquement en libérant le produit actif. To remedy this drawback, it is possible to use a packaging according to the invention consisting of an envelope made of a biodegradable material containing, as active substance, phytosanitary microorganisms capable of destroying the parasites considered. During the rainy period, the envelope dissolves automatically, releasing the active product.

Exemple 2 : Utilisation dans le domaine pharmaceutique.Example 2: Use in the pharmaceutical field.

Pour obtenir un emballage conforme à l'ånven- tion, on a disposé une dose unitaire prédéterminée d'une substance médicamenteuse dans une enveloppe réalisée partir d'un film en un matériau biodégradablesoluble dans l'eau et pouvant etre ingéré par l'homme ; cette enveloppe est fermée par thermosoudage. In order to obtain a packaging in accordance with the invention, a predetermined unit dose of a medicinal substance was placed in an envelope made from a film of a biodegradable material soluble in water and capable of being ingested by humans; this envelope is closed by heat sealing.

Pour ingérer cette dose, le patient plonge l'emballage dans un verre d'eau froide ou tiède. L'ensemble de l'emballage se dissout alors plus ou moins rapidement, et le patient peut boire le contenu du verre. Le patient n'a pas à déchirer l'enveloppe ni à toucher la substance médicamenteuse et il est toujours certain de respecter la posologie prescrite.  To ingest this dose, the patient immerses the packaging in a glass of cold or lukewarm water. The entire package then dissolves more or less quickly, and the patient can drink the contents of the glass. The patient does not have to tear the envelope or touch the drug substance and it is always certain to respect the prescribed dosage.

Claims (9)

REVENDICATIONS 10) Emballage constitué par une enveloppe fermée contenant une dose d'une substance liquide ou pulvérulente active dans un domaine particulier, notamment en pharmacie, caractérisé en ce que l'enveloppe est réalisée à partir d'un film en un matériau biodégradable soluble dans l'eau et pouvant être ingéré par l'homme ou l'animal. 10) Package consisting of a closed envelope containing a dose of a liquid or pulverulent substance active in a particular field, in particular in pharmacy, characterized in that the envelope is produced from a film of a biodegradable material soluble in l water and can be ingested by humans or animals. 20) Emballage selon la revendication 1, caractérisé en ce que le matériau biodégradable n'est soluble qu'à partir d'une température de seuil prédéterminée. 20) Packaging according to claim 1, characterized in that the biodegradable material is soluble only from a predetermined threshold temperature. 30) Emballage selon l'une quelconque des revendications 1 et 2, caractérisé en ce que le matériau biodégradable renferme de la gélatine. 30) Packaging according to any one of claims 1 and 2, characterized in that the biodegradable material contains gelatin. 40) Emballage selon l'une quelconque des revendications 1 à 3, caractérisé en ce que le matériau biodégradable renferme de l'alcool polyvinylique. 40) Packaging according to any one of claims 1 to 3, characterized in that the biodegradable material contains polyvinyl alcohol. 50) Emballage selon l'une quelconque des revendications 1 à 4, caractérisé en ce que le matériau biodégradable renferme du glycérol. 50) Packaging according to any one of claims 1 to 4, characterized in that the biodegradable material contains glycerol. 60) Emballage selon l'une quelconque des revendications 1 à 5, caractérisé en ce que le matériau biodégradable est thermosoudable. 60) Packaging according to any one of claims 1 to 5, characterized in that the biodegradable material is heat sealable. 70) Emballage selon l'une quelconque des re-vendications 1 à 6, caractérisé en ce que le matériau biodégradable est transparent. 70) Packaging according to any one of re-vendications 1 to 6, characterized in that the biodegradable material is transparent. 80) Emballage selon l'une quelconque des revendications 1 à 6, caractérisé en ce que le matériau biodégradable est opaque. 80) Packaging according to any one of claims 1 to 6, characterized in that the biodegradable material is opaque. 90) Emballage selon l'une quelconque des revendications 1 à 7, caractérisé en ce que le matériau biodégradable peut être m:arqué ou imprimé pour permettre l'identification de son contenu.  90) Packaging according to any one of claims 1 to 7, characterized in that the biodegradable material can be m: arched or printed to allow the identification of its content.
FR8610795A 1986-07-25 1986-07-25 Package constituted by a closed envelope containing a dose of an active substance Pending FR2601930A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8610795A FR2601930A1 (en) 1986-07-25 1986-07-25 Package constituted by a closed envelope containing a dose of an active substance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8610795A FR2601930A1 (en) 1986-07-25 1986-07-25 Package constituted by a closed envelope containing a dose of an active substance

Publications (1)

Publication Number Publication Date
FR2601930A1 true FR2601930A1 (en) 1988-01-29

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FR8610795A Pending FR2601930A1 (en) 1986-07-25 1986-07-25 Package constituted by a closed envelope containing a dose of an active substance

Country Status (1)

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FR (1) FR2601930A1 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0518820A1 (en) * 1991-06-11 1992-12-16 Greither, Peter Packaging dunnage
US6281183B1 (en) 1999-03-17 2001-08-28 Unilever Home & Personal Care, Division Of Conopco, Inc. Process for producing a water soluble package
US6363693B1 (en) 1999-03-17 2002-04-02 Unilever Home & Personal Care, Usa Process for producing a water soluble package
US6378274B1 (en) * 1999-03-17 2002-04-30 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Process for producing a water soluble package
US6451750B2 (en) 2000-04-14 2002-09-17 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Water soluble package and liquid contents thereof
US6479448B2 (en) 2000-05-15 2002-11-12 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Liquid detergent composition
US7083047B2 (en) 2002-10-03 2006-08-01 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Polymeric film for water soluble package
DE102007042450A1 (en) 2007-09-06 2009-04-23 Siggelkow, Andreas Water-soluble packaging with functional depot and its manufacture and use
US7674761B2 (en) 2001-03-16 2010-03-09 Unilever Home & Personal Care, Division Of Conopco, Inc. Water soluble sachet with a dishwashing enhancing particle

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3277009A (en) * 1961-10-03 1966-10-04 Gen Aniline & Film Corp Water-soluble package and method for making and using same
FR2087185A5 (en) * 1970-05-08 1971-12-31 Rousselot Kuhlmann Edible wrappings - based on gelatine for use with food stuffs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3277009A (en) * 1961-10-03 1966-10-04 Gen Aniline & Film Corp Water-soluble package and method for making and using same
FR2087185A5 (en) * 1970-05-08 1971-12-31 Rousselot Kuhlmann Edible wrappings - based on gelatine for use with food stuffs

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0518820A1 (en) * 1991-06-11 1992-12-16 Greither, Peter Packaging dunnage
US6281183B1 (en) 1999-03-17 2001-08-28 Unilever Home & Personal Care, Division Of Conopco, Inc. Process for producing a water soluble package
US6363693B1 (en) 1999-03-17 2002-04-02 Unilever Home & Personal Care, Usa Process for producing a water soluble package
US6378274B1 (en) * 1999-03-17 2002-04-30 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Process for producing a water soluble package
US6451750B2 (en) 2000-04-14 2002-09-17 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Water soluble package and liquid contents thereof
US6479448B2 (en) 2000-05-15 2002-11-12 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Liquid detergent composition
US7674761B2 (en) 2001-03-16 2010-03-09 Unilever Home & Personal Care, Division Of Conopco, Inc. Water soluble sachet with a dishwashing enhancing particle
US8367599B2 (en) 2001-03-16 2013-02-05 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Dishwashing composition with particles
US7083047B2 (en) 2002-10-03 2006-08-01 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Polymeric film for water soluble package
DE102007042450A1 (en) 2007-09-06 2009-04-23 Siggelkow, Andreas Water-soluble packaging with functional depot and its manufacture and use
DE102007042450B4 (en) * 2007-09-06 2009-12-31 Andreas Siggelkow Water-soluble packaging with functional depot and method for its production and use of the packaging

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