FR2544320B1 - Amides bis (2,2-dimethyl-1-aziridinyl) phosphiniques et leur utilisation dans le traitement de tumeurs - Google Patents

Amides bis (2,2-dimethyl-1-aziridinyl) phosphiniques et leur utilisation dans le traitement de tumeurs

Info

Publication number: FR2544320B1
Authority: FR; France
Prior art keywords: aziridinyl; tumors; bis; dimethyl; treatment
Prior art date: 1983-04-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR8310767A

Other languages

English (en)

Other versions

FR2544320A1 (fr

Inventor

Thomas J Bardos

Michael E Perlman

Joan E Macdiarmid

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

New York University NYU

Original Assignee

New York University NYU

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-04-12

Filing date

1983-06-29

Publication date

1986-07-11

1983-06-29 Application filed by New York University NYU filed Critical New York University NYU

1984-10-19 Publication of FR2544320A1 publication Critical patent/FR2544320A1/fr

1986-07-11 Application granted granted Critical

1986-07-11 Publication of FR2544320B1 publication Critical patent/FR2544320B1/fr

Status Expired legal-status Critical Current

Links

-1 2,2-DIMETHYL-1-AZIRIDINYL Chemical class 0.000 title 1
206010028980 Neoplasm Diseases 0.000 title 1
150000001408 amides Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/564—Three-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FR8310767A 1983-04-12 1983-06-29 Amides bis (2,2-dimethyl-1-aziridinyl) phosphiniques et leur utilisation dans le traitement de tumeurs Expired FR2544320B1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/484,213 US4544501A (en)	1982-04-12	1983-04-12	Bis(2,2-dimethyl-1-aziridinyl)phosphinic amides for use in the treatment of tumors

Publications (2)

Publication Number	Publication Date
FR2544320A1 FR2544320A1 (fr)	1984-10-19
FR2544320B1 true FR2544320B1 (fr)	1986-07-11

Family

ID=23923219

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR8310767A Expired FR2544320B1 (fr)	1983-04-12	1983-06-29	Amides bis (2,2-dimethyl-1-aziridinyl) phosphiniques et leur utilisation dans le traitement de tumeurs

Country Status (9)

Country	Link
US (1)	US4544501A (fr)
JP (1)	JPS59190998A (fr)
BE (1)	BE897173A (fr)
CA (1)	CA1205080A (fr)
DE (1)	DE3323316A1 (fr)
ES (1)	ES523724A0 (fr)
FR (1)	FR2544320B1 (fr)
GB (1)	GB2138002B (fr)
IT (1)	IT1212989B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4702200A (en) *	1986-04-16	1987-10-27	Simington Products Company	Livestock head holder
US20030129186A1 (en)	2001-07-25	2003-07-10	Biomarin Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
SI1889198T1 (sl)	2005-04-28	2015-02-27	Proteus Digital Health, Inc.	Farma-informacijski sistem
EP2063905B1 (fr)	2006-09-18	2014-07-30	Raptor Pharmaceutical Inc	Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap)
DK2398500T3 (da)	2009-02-20	2019-05-13	2 Bbb Medicines B V	Glutathion-baseret lægemiddelafgivelsessystem
ES2942923T3 (es)	2009-05-06	2023-06-07	Laboratory Skin Care Inc	Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2663705A (en) *	1951-07-25	1953-12-22	American Cyanamid Co	Phosphoric acid derivatives and methods of preparing the same
US2606900A (en) *	1951-07-25	1952-08-12	American Cyanamid Co	Phosphoric acid derivatives and methods of preparing the same
US2670347A (en) *	1952-01-08	1954-02-23	American Cyanamid Co	Thiophosphoric acid derivatives and method of preparing the same
GB864021A (en) *	1956-05-19	1961-03-29	Hoechst Ag	Manufacture of phosphorus-containing ethylene imine type compounds
BE575311A (fr) *	1958-02-01
US3201313A (en) *	1959-08-13	1965-08-17	Armour Pharma	Inhibition of cellular reproduction

1983
- 1983-04-12 US US06/484,213 patent/US4544501A/en not_active Expired - Fee Related
- 1983-06-20 CA CA000430746A patent/CA1205080A/fr not_active Expired
- 1983-06-24 GB GB08317239A patent/GB2138002B/en not_active Expired
- 1983-06-28 DE DE19833323316 patent/DE3323316A1/de not_active Ceased
- 1983-06-29 FR FR8310767A patent/FR2544320B1/fr not_active Expired
- 1983-06-29 IT IT8367709A patent/IT1212989B/it active
- 1983-06-30 ES ES523724A patent/ES523724A0/es active Granted
- 1983-06-30 JP JP58119442A patent/JPS59190998A/ja active Pending
- 1983-06-30 BE BE1/10825A patent/BE897173A/nl not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE3323316A1 (de)	1984-10-18
ES8500961A1 (es)	1984-11-01
BE897173A (nl)	1984-01-02
US4544501A (en)	1985-10-01
CA1205080A (fr)	1986-05-27
ES523724A0 (es)	1984-11-01
IT8367709A0 (it)	1983-06-29
IT1212989B (it)	1989-12-07
GB2138002B (en)	1987-01-07
JPS59190998A (ja)	1984-10-29
GB8317239D0 (en)	1983-07-27
GB2138002A (en)	1984-10-17
FR2544320A1 (fr)	1984-10-19

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Legal Events

Date	Code	Title	Description
1992-04-30	ST	Notification of lapse