FR2532280A1 - Packaging for the separate storage of mutually incompatible fluids which allows them to be mixed at the time of use - Google Patents

Packaging for the separate storage of mutually incompatible fluids which allows them to be mixed at the time of use Download PDF

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Publication number
FR2532280A1
FR2532280A1 FR8214525A FR8214525A FR2532280A1 FR 2532280 A1 FR2532280 A1 FR 2532280A1 FR 8214525 A FR8214525 A FR 8214525A FR 8214525 A FR8214525 A FR 8214525A FR 2532280 A1 FR2532280 A1 FR 2532280A1
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France
Prior art keywords
containers
container
packaging
packaging according
mixed
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8214525A
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French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
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Individual
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Priority to FR8214525A priority Critical patent/FR2532280A1/en
Publication of FR2532280A1 publication Critical patent/FR2532280A1/en
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces
    • B65D81/3211—Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The packaging consists of two containers stopped by caps, and a device allowing the caps to be pierced. The device ensures the mechanical connection between the containers and connects their respective contents together. Applications in particular in the pharmaceutical field, especially for inhalation products containing Peruvian Balsam.

Description

Conditionnement pour conservation séparée de fluides incompatibles entre eux, et permettant leur mélange au moment de l'emploi.Packaging for separate storage of fluids incompatible with each other, and allowing their mixing at the time of use.

La présente invention concerne un conditionnement pour la conservation sépare de deux fluides incompatibles entre eux, destinés à entre employés en mélange. The present invention relates to a packaging for the separate preservation of two fluids incompatible with each other, intended for between employees in mixture.

On rencontre fréquemment ce problème dans le domaine pharmaceutique. This problem is frequently encountered in the pharmaceutical field.

Le conditionnement selon 1 invention permet de plus d'opérer de manière très pratique la reunion des deux fluides juste avant l'einploi du mélange ainsi formé, dans d'excellentes conditions d'hygiène. The packaging according to 1 invention also makes it possible to operate in a very practical manner the reunion of the two fluids just before the use of the mixture thus formed, in excellent hygienic conditions.

L'invention convient donc dans tous les cas, qui sont nombreux notamment dans le domaine pharmaceutique, où l'on ne peut mélanger deux composants qu'au moment de leur emploi, ou lorsque la stabilité du mélange considéré est Si médiocre qu'elle en interdit une conservation raisonnable, soit en rayon, soit chez le patient, ce qui en interdit-en fait la commercialisation. The invention is therefore suitable in all cases, which are numerous in particular in the pharmaceutical field, where two components can only be mixed at the time of their use, or when the stability of the mixture considered is so poor that it prohibits reasonable storage, either on the shelf or in the patient, which prohibits its marketing.

D'autres caractéristiques et avantages de l'invention seront mieux compris è la lecture de la description qui va suivre, et en se référant au dessin annexé sur lequel
- la figure 1 représente en coupe deux récipients et leur dispositif de liaison, selon une des variantes de l'invention
- la figure 2 représente l'assemblage obtenu selon la figure 1
- la figure 3 représente une variante du conditionnement selon les figures 1 et 2, selon laquelle le goulot de chaque récipient présente un bossage sur lequel vient s'adapter exactement le dispositif de liaison, la géométrie du bossage étant telle que, que lors de l'écoulement du fluide contenu dans le récipient supérieur vers lue récipient inférieur, la totalité du fluide est bien transferée, ce qui peut entre essentiel pour des produits très précisément dosés.Other characteristics and advantages of the invention will be better understood on reading the description which follows, and with reference to the appended drawing in which
- Figure 1 shows in section two containers and their connecting device, according to one of the variants of the invention
- Figure 2 shows the assembly obtained according to Figure 1
- Figure 3 shows a variant of the packaging according to Figures 1 and 2, according to which the neck of each container has a boss on which the connection device exactly fits, the geometry of the boss being such that, when flow of the fluid contained in the upper container to the lower container, all of the fluid is well transferred, which can be essential for very precisely dosed products.

- la figure 4 représente une seconde possibilité de réalisation de l'invention. - Figure 4 shows a second embodiment of the invention.

Sur les quatre figures annexées, les mêmes références ont les memes significations, qui sont les suivantes 1- premier récipient; 2- second récipient; 3- dispositif de liaison; 4- goulot des récipients; 5- partie filetée du goulot; 6- partie tarandée du dispositif de liaison. In the four appended figures, the same references have the same meanings, which are as follows: 1- first container; 2- second container; 3- connecting device; 4- necks of the containers; 5- threaded part of the neck; 6- tared part of the connection device.

Naturellement, les parties 5 et 6 sont destinées à coopérer et doivent donc entre totalement compatibles en ce qui concerne les différents diamètres, les filetage-taraudage, etc., ces détails de réalisation étant a la portée de tout homme de métier. Naturally, parts 5 and 6 are intended to cooperate and must therefore be fully compatible with regard to the different diameters, thread-tapping, etc., these details of construction being within the reach of any skilled person.

On notera aussi que, sur la variante représentée figure 4, les parties filetée et taraudée sont inversées. It will also be noted that, in the variant shown in FIG. 4, the threaded and tapped parts are reversed.

7- ouverture donnant accès a la chambre 9 de mise en communication; 8- opercule; 8'- variante alternative de positionnement de l'opercule; 9- chambre de mise en communication, après vissage du dispositif sur
chacun des deux goulots, des récipients 1 et 2; 10- bossage; 11- partie tronconique assurant, au moment du vissage, la perforation des opercule, et délimitant par ailleurs la chambre 9. 7- opening giving access to room 9 for communication; 8- seal; 8'- alternative variant for positioning the cover; 9- connecting chamber, after screwing the device onto
each of the two necks, containers 1 and 2; 10- boss; 11- frustoconical part ensuring, at the time of screwing, the perforation of the cover, and further delimiting the chamber 9.

On notera que, dans la variante représentée sur la figure 4, la p-erforation est effectuée manuellement lorsque l'opercule est en position 8, ou bien au cours du vissage lorsque l'opercule est en position 8'. Note that, in the variant shown in Figure 4, the p-erforation is performed manually when the cover is in position 8, or during screwing when the cover is in position 8 '.

Au niveau de l'ouverture 7, la partie tronconique 11 présentera de préférence un biseau assurant la meilleure perforation possible de l'opercule. At the opening 7, the frustoconical part 11 preferably has a bevel ensuring the best possible perforation of the cover.

En p--trticulier, on évitera tout risque de voir une partie de l'opercule se détacher par un biseautage approprié. In particular, we will avoid any risk of seeing a part of the seal come off by an appropriate bevel.

Ces détails sont également à la portée de tout homme du métier. These details are also within the reach of any person skilled in the art.

d- Dans la variante figures 1, 2 et 3, distance permettant de ne
perforer l'opercule qu'après le début du vissage.d- In the variant Figures 1, 2 and 3, distance allowing not
perforate the seal only after the start of screwing.

12- prise d'air.12- air intake.

L'invention consiste donc en un conditionnement comportant deux récipients obturés par un opercule déchirable, combinés à un dispositif de liaison comportant à chacune de ses deux extrémités
- un moyen pour s'adapter de manière étanche ou
sensiblement étanche aux fluides au goulot du rAci-
pient en regard, et
- un moyen perforant l'opercule lors de l'opération
ci-dessous d'adaptation, et-mettant simultanément les
deux récipients en communication.The invention therefore consists of a package comprising two containers closed by a tearable lid, combined with a connecting device comprising at each of its two ends
- a means for tightly fitting or
substantially fluid tight at the neck of the rAci-
are watching, and
- a means perforating the cover during the operation
below adaptation, and-simultaneously putting the
two communicating containers.

Le moyen d'adaptation préféré est le vissage, mais on peut aussi envisager un encllquetage, et des dispositifs analogues. The preferred means of adaptation is screwing, but one can also envisage an interlocking, and similar devices.

Bien entendu, les contenances des deux récipients seront adaptées de façon que, par exemple, le contenu du récipient 1 trouve la place de s'ecouler dans le récipient 2. Of course, the capacities of the two containers will be adapted so that, for example, the content of the container 1 finds the place to flow into the container 2.

Pour permettre cet écoulement, on pourra, soit simplement agiter ou retourner plusieurs fois l'ensemble, soit prévoir une prise d'air ou- un dispositif type piston au niveau du récipient "supérieur". To allow this flow, one can either simply shake or turn the assembly several times, or provide an air intake or- a piston type device at the level of the "upper" container.

On peut également prévoir une prise d'air directement sur le dispositif 3 comme représenté sur la figure 1, agencé de manière que le fluide du récipient 1 puisse s'écouler sans perte tandis que l'air s'échappe par la prise d'air 12. One can also provide an air intake directly on the device 3 as shown in Figure 1, arranged so that the fluid from the container 1 can flow without loss while the air escapes through the air intake 12.

Alternativement, on peut également placer le récipient "récepteur" sous vide pour qu'un phénomène d'aspiration se produise. Alternatively, it is also possible to place the "receiving" container under vacuum so that an aspiration phenomenon occurs.

Par "fluides", on entend tous les produits pouvant s'écouler d'un récipient vers l'autre : liquides, poudres fines, petits gralulés, etc. Toutes les combinaisons sont naturellement envisageables par exemple mélange de deux liquides, d'une poudre et d'un solvant, par exemple pour injection, etc. L'un des produits peut même être solide si par exemple l'autre est un solvant. By "fluids" is meant all the products which can flow from one container to another: liquids, fine powders, small pellets, etc. All combinations are naturally possible, for example mixing two liquids, a powder and a solvent, for example for injection, etc. One of the products can even be solid if for example the other is a solvent.

Les matières constitutives des récipients seront en rapport avec leur contenu : matière plastique, notamment de qualité pharaceutique, verre, verre teinté, etc. The constituent materials of the containers will be related to their content: plastic, in particular pharmaceutical grade, glass, tinted glass, etc.

Le dispositif de liaison pourra etre en matière plastique notamment de qualite-pharmaceutique, et présenté s-ous sachet stérile. The connection device may be made of plastic, in particular of pharmaceutical quality, and presented in sterile sachet.

Notamment dans l'industrie pharmaceutique, les applications de l'insention sont très nombreuses. Nous citerons à titre non limitatif
- collyres
- solutions ou suspensions injectables.In particular in the pharmaceutical industry, the applications of insistence are very numerous. We will quote without limitation
- eye drops
- injectable solutions or suspensions.

L'invention permet en particulier de résoudre le problème de la conservation de formules pour inhalation contenant du baume du Pérou. The invention makes it possible in particular to solve the problem of the conservation of formulas for inhalation containing balsam of Peru.

La formule suivante
menthol 0,50 g
Baume du Pérou 10 g
Teinture de benjoin 20 g
Teinture d'eucalyptus 30 g
Alcool à 90' qs lrO g est très concentrée en baume du Pérou et est donc très instable.The following formula
menthol 0.50 g
Peruvian balm 10 g
Benzoin tincture 20 g
Eucalyptus tincture 30 g
Alcohol at 90 'qs lrO g is very concentrated in Peru balsam and is therefore very unstable.

II est totalement impossible pour cette raison de la préparer à l'avance. It is therefore completely impossible to prepare it in advance.

Selon l'invention, le baume du Pérou est placé dans l'un des récipients tandis que le second récipient reçoit les autres composants. According to the invention, the Peru balsam is placed in one of the containers while the second container receives the other components.

Le patient ou l'utilisateur réalise le mélange comme il a été dit ci-dessus et dispose ensuite d'environ deux semaines (durée de conservation du mélange) pour utiliser la formulation. The patient or user makes the mixture as stated above and then has approximately two weeks (shelf life of the mixture) to use the formulation.

Dans cet exemple, les flacons 1 et 2 doivent être en verre car on sait que le baume du Pérou présente la propriété de teinter rapidement les matières plastiques par infiltration dans celles-Li.  In this example, the bottles 1 and 2 must be made of glass because it is known that the Peru balm has the property of quickly tinting plastic materials by infiltration into them.

L'invention s'applique également au cas où plus de deux composants doivent étre mélangés. I1 suffit dans ce cas
- de prévoir un récipient "inférieur" 2 de vulume suffisant et
- de réaliser successivement la mise en communication avec plusieurs récipients "supérieur" de type 1 (selon la variante de la figure 1, préférentiellement). The invention also applies to the case where more than two components have to be mixed. I1 is sufficient in this case
- provide a "lower" container 2 of sufficient vulume and
- To carry out successively the communication with several "upper" type 1 containers (preferably according to the variant of FIG. 1).

Claims (6)

REVENDICATIONS 1. Conditionnement pour la conservation de fluides incompatibles entre eux et destinés à etre utilisés en mélange, et pour ledit mélange, caractérisé en ce ce qu'il consiste en1. Packaging for the preservation of fluids which are incompatible with each other and intended to be used as a mixture, and for said mixture, characterized in that it consists of - au moins deux récipients dont chacun est obturé par un opercule déchirable et contient un fluide, éventuellement composite, stable; et - At least two containers, each of which is closed by a tearable seal and contains a fluid, possibly composite, stable; and - un dispositif de liaison comportant à chacune de ses deux extrémités  - a connection device comprising at each of its two ends un moyen pour s'adapter de manière étanche ou means for sealingly fitting or sensiblement étanche aux fluides au goulot du substantially fluid tight at the neck of the récipient en regard comportant lui-mame un moyen opposite container itself comprising a means de ce type, et of this type, and un moyen perforant ledit opercule lors de I'opé-  a means perforating said cover during the operation ration ci-dessus dtadaptation du dispositif au above ration of adaptation of the device to goulot et mettant simultanément les deux récipients neck and simultaneously placing the two containers en communication. in communication. 2. Conditionnement selon la revendication 1, caractérisé en ce que le nombre de récipients est égal à deux.2. Packaging according to claim 1, characterized in that the number of containers is equal to two. 3. Conditionnement selon la revendication 1 ou 2, caractérisé en ce que le moyen d'adaptation est une combinaison filetage/taraudage.3. Packaging according to claim 1 or 2, characterized in that the adaptation means is a thread / tapping combination. 4. Conditionnement selon l'une quelconque des revendications 1 à 3 caractérisé en ce que le dispositif présente une prise d'air ne permettant pas la fuite du fluide dont elle assure l'ecoule- ment par gravité du récipient supérieur vers le récipient inférieur.4. Packaging according to any one of claims 1 to 3 characterized in that the device has an air intake which does not allow the leakage of the fluid which it ensures the flow by gravity from the upper container to the lower container. 5. Conditionnement selon l'une quelconque des revendications 1 à 4, caractérisé en ce que les deux récipients sont en verre. 5. Packaging according to any one of claims 1 to 4, characterized in that the two containers are made of glass. 6. Applications du conditionnement selon'une quelconque des revendications 1 à 5 aux compositions à usage pharmaceutique, notamment la suivante - premier récipient : baume du Pérou 10 g - second récipient : menthol 0,50 g6. Applications of the packaging according to any one of claims 1 to 5 to compositions for pharmaceutical use, in particular the following - first container: balsam of Peru 10 g - second container: menthol 0.50 g teinture de benjoin 20 g tincture of benzoin 20 g teinture d'eucalyptus 30 g eucalyptus tincture 30 g Alcool à 90 qs 100 g (compte tenu des Alcohol at 90 qs 100 g (taking into account 1 g de baume di Pérou).  1 g of Peru balm).
FR8214525A 1982-08-24 1982-08-24 Packaging for the separate storage of mutually incompatible fluids which allows them to be mixed at the time of use Withdrawn FR2532280A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8214525A FR2532280A1 (en) 1982-08-24 1982-08-24 Packaging for the separate storage of mutually incompatible fluids which allows them to be mixed at the time of use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8214525A FR2532280A1 (en) 1982-08-24 1982-08-24 Packaging for the separate storage of mutually incompatible fluids which allows them to be mixed at the time of use

Publications (1)

Publication Number Publication Date
FR2532280A1 true FR2532280A1 (en) 1984-03-02

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0263313A1 (en) * 1986-10-08 1988-04-13 Blendax GmbH Two component recipient
FR2628633A1 (en) * 1988-03-15 1989-09-22 Mercier Jean Strong, stable solutions of balsam of Peru - using over 90 per cent by vol ethanol as solvent
DE10022835A1 (en) * 2000-05-10 2001-11-15 Kellermann Johann Connection mechanism for mixing fluid, granulate, powder or soluble components, comprises closure with or without thread, lid and mantle
WO2004028923A1 (en) * 2002-09-24 2004-04-08 Sealants International Limited Multiple component container system
WO2004031051A1 (en) * 2002-10-03 2004-04-15 Sealants International Limited Tube container system
GB2471104A (en) * 2009-06-17 2010-12-22 Ian Singleton Device for transfer of product from refill container to applicator container
CH707118A1 (en) * 2012-10-23 2014-04-30 Alpla Werke Container and use of the container for adding a blending component in a second container.
CN105966738A (en) * 2016-07-14 2016-09-28 刘慧娟 Toothpaste tube connecting device for toothpaste transfer
CZ308255B6 (en) * 2018-06-29 2020-03-25 Regshare, s.r.o. Container, in particular for liquids and a mixing valve, in particular for safely mixing and spilling liquids
IT202000014743A1 (en) * 2020-06-19 2021-12-19 Orofino Pharm Group Srl SYSTEM FOR HEATING AND ADMINISTRATION OF LIQUIDS

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1010029A (en) * 1948-07-23 1952-06-06 Twin needle connection
FR1545963A (en) * 1967-11-07 1968-11-15 Abc Ist Biolog Chem Spa Packaging of two separate and miscible substances, at least one of which is liquid, with transfer device
US3809289A (en) * 1971-12-20 1974-05-07 Automatic Liquid Packaging Mixing containers
US3885607A (en) * 1973-11-16 1975-05-27 Richard I Peltier Device for providing fluid communication between two sealed vessels
FR2294937A1 (en) * 1974-12-18 1976-07-16 Neve Rene Two-compartment bottle for two-component pharmaceutical prods. - which must be kept apart until the moment of injection
FR2302134A1 (en) * 1975-02-28 1976-09-24 Merieux Inst Appts. to transfer liq. from one closed container to another - esp. for feeding solvent to vaccine doses aseptically
FR2340872A1 (en) * 1976-02-12 1977-09-09 Bert Rene Adapter for joining containers - has cylindrical body with internal threads outer and inner connector portions allowing assembly of several together

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1010029A (en) * 1948-07-23 1952-06-06 Twin needle connection
FR1545963A (en) * 1967-11-07 1968-11-15 Abc Ist Biolog Chem Spa Packaging of two separate and miscible substances, at least one of which is liquid, with transfer device
US3809289A (en) * 1971-12-20 1974-05-07 Automatic Liquid Packaging Mixing containers
US3885607A (en) * 1973-11-16 1975-05-27 Richard I Peltier Device for providing fluid communication between two sealed vessels
FR2294937A1 (en) * 1974-12-18 1976-07-16 Neve Rene Two-compartment bottle for two-component pharmaceutical prods. - which must be kept apart until the moment of injection
FR2302134A1 (en) * 1975-02-28 1976-09-24 Merieux Inst Appts. to transfer liq. from one closed container to another - esp. for feeding solvent to vaccine doses aseptically
FR2340872A1 (en) * 1976-02-12 1977-09-09 Bert Rene Adapter for joining containers - has cylindrical body with internal threads outer and inner connector portions allowing assembly of several together

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0263313A1 (en) * 1986-10-08 1988-04-13 Blendax GmbH Two component recipient
FR2628633A1 (en) * 1988-03-15 1989-09-22 Mercier Jean Strong, stable solutions of balsam of Peru - using over 90 per cent by vol ethanol as solvent
DE10022835A1 (en) * 2000-05-10 2001-11-15 Kellermann Johann Connection mechanism for mixing fluid, granulate, powder or soluble components, comprises closure with or without thread, lid and mantle
DE10022835B4 (en) * 2000-05-10 2004-10-28 Kellermann, Johann Mechanism for mixing liquids and granules
WO2004028923A1 (en) * 2002-09-24 2004-04-08 Sealants International Limited Multiple component container system
WO2004031051A1 (en) * 2002-10-03 2004-04-15 Sealants International Limited Tube container system
GB2471104A (en) * 2009-06-17 2010-12-22 Ian Singleton Device for transfer of product from refill container to applicator container
US8474495B2 (en) 2009-06-17 2013-07-02 Ian Singleton Device for transfer of product from refill container to applicator container without exposure to atmosphere
GB2471104B (en) * 2009-06-17 2013-08-14 Ian Singleton Device for transfer of product from refill container to applicator container without exposure to atmosphere
CH707118A1 (en) * 2012-10-23 2014-04-30 Alpla Werke Container and use of the container for adding a blending component in a second container.
CN105966738A (en) * 2016-07-14 2016-09-28 刘慧娟 Toothpaste tube connecting device for toothpaste transfer
CZ308255B6 (en) * 2018-06-29 2020-03-25 Regshare, s.r.o. Container, in particular for liquids and a mixing valve, in particular for safely mixing and spilling liquids
IT202000014743A1 (en) * 2020-06-19 2021-12-19 Orofino Pharm Group Srl SYSTEM FOR HEATING AND ADMINISTRATION OF LIQUIDS
WO2021255575A1 (en) * 2020-06-19 2021-12-23 Orofino Pharmaceuticals Group Srl Pre-packaged liquid container and corresponding device

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