FR2513117B1 - Agent contre la maladie de parkinson, comprenant de la threo-3, 4-dihydroxyphenylserine et un inhibiteur de decarboxylase - Google Patents

Agent contre la maladie de parkinson, comprenant de la threo-3, 4-dihydroxyphenylserine et un inhibiteur de decarboxylase

Info

Publication number
FR2513117B1
FR2513117B1 FR8215806A FR8215806A FR2513117B1 FR 2513117 B1 FR2513117 B1 FR 2513117B1 FR 8215806 A FR8215806 A FR 8215806A FR 8215806 A FR8215806 A FR 8215806A FR 2513117 B1 FR2513117 B1 FR 2513117B1
Authority
FR
France
Prior art keywords
dihydroxyphenylserine
threo
parkinson
disease agent
decarboxylase inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8215806A
Other languages
English (en)
Other versions
FR2513117A1 (fr
Inventor
Hirotaro Narabayashi
Tomoyoshi Kondo
Akira Hayashi
Tomokazu Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of FR2513117A1 publication Critical patent/FR2513117A1/fr
Application granted granted Critical
Publication of FR2513117B1 publication Critical patent/FR2513117B1/fr
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR8215806A 1981-09-22 1982-09-20 Agent contre la maladie de parkinson, comprenant de la threo-3, 4-dihydroxyphenylserine et un inhibiteur de decarboxylase Expired FR2513117B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56150082A JPS5852219A (ja) 1981-09-22 1981-09-22 パ−キンソン病治療剤

Publications (2)

Publication Number Publication Date
FR2513117A1 FR2513117A1 (fr) 1983-03-25
FR2513117B1 true FR2513117B1 (fr) 1986-01-24

Family

ID=15489114

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8215806A Expired FR2513117B1 (fr) 1981-09-22 1982-09-20 Agent contre la maladie de parkinson, comprenant de la threo-3, 4-dihydroxyphenylserine et un inhibiteur de decarboxylase

Country Status (13)

Country Link
US (1) US4497826A (fr)
JP (1) JPS5852219A (fr)
AU (2) AU556542B2 (fr)
BE (1) BE894451A (fr)
CA (1) CA1184501A (fr)
CH (1) CH650926A5 (fr)
DE (1) DE3235093A1 (fr)
FR (1) FR2513117B1 (fr)
GB (1) GB2106388B (fr)
IT (1) IT1212668B (fr)
NL (1) NL189648C (fr)
NZ (1) NZ201864A (fr)
SE (1) SE462781B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6067420A (ja) * 1983-09-22 1985-04-17 Sumitomo Chem Co Ltd 精神運動興奮抑制剤
AU575849B2 (en) * 1983-09-22 1988-08-11 Sumitomo Chemical Company, Limited Pharmaceutical composition and method for treatment of psychomotor excitement
NZ209514A (en) * 1983-09-22 1988-03-30 Sumitomo Chemical Co Pharmaceutical compositions containing erythro-3,4-dihydroxyphenylserine and a decarboxylase inhibitor
JPS60132935A (ja) * 1983-12-20 1985-07-16 Sumitomo Chem Co Ltd フエニルセリン誘導体及びその製造方法
JPS6185318A (ja) * 1984-10-04 1986-04-30 Sumitomo Seiyaku Kk 利尿薬
ZA889189B (en) * 1986-06-16 1989-08-30 Merck & Co Inc Controlled release combination of carbidopa/levodopa
US4983400A (en) * 1986-06-16 1991-01-08 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
US4832957A (en) * 1987-12-11 1989-05-23 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
US4863962A (en) * 1988-03-02 1989-09-05 Fidia-Georgetown Institute For The Neurosciences D-DOPA, pharmaceutically acceptable salts thereof, and methods of treating Parkinson's disease
PT99864B (pt) * 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
DE4101873C2 (de) * 1991-01-23 1993-12-09 Isis Pharma Gmbh Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände
JP3559572B2 (ja) 1993-01-29 2004-09-02 住友製薬株式会社 急性痛および慢性痛用鎮痛剤
JP3764179B2 (ja) * 1994-07-05 2006-04-05 克寛 西野 運動・意識または言語障害の機能改善剤
US5668114A (en) * 1996-05-08 1997-09-16 Birkmayer Pharmaceuticals NADH and NADPH pharmaceuticals for treating hypertension
GB2348371B (en) * 2000-03-14 2001-04-04 Soares Da Silva Patricio Compositions comprising blockers of L-DOPA renal cell transfer for the treatment of Parkinson's disease
US8158149B2 (en) * 2004-05-12 2012-04-17 Chelsea Therapeutics, Inc. Threo-DOPS controlled release formulation
WO2004100929A1 (fr) 2003-05-12 2004-11-25 Synergia Pharma, Inc. Formulation de threo-dops a liberation regulee
WO2005025561A1 (fr) * 2003-09-04 2005-03-24 Synergia Pharma, Inc. Compositions et methodes de traitement de l'intolerance orthostatique
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
US7786126B2 (en) * 2006-06-16 2010-08-31 Solvay Pharmaceuticals B.V. Combination preparations comprising SLV308 and a dopamine agonist
WO2008003028A2 (fr) * 2006-06-28 2008-01-03 Chelsea Therapeutics, Inc. Compositions pharmaceutiques comprenant de la 3,4-dihydroxyphénylsérine
EP2468271B1 (fr) * 2007-03-09 2014-07-16 Chelsea Therapeutics, Inc. Composition pharmaceutique à base de droxidopa pour le traitement de la fibromyalgie
CA2686723A1 (fr) * 2007-05-07 2008-11-13 Chelsea Therapeutics, Inc. Droxidopa et composition pharmaceutique de celle-ci pour le traitement des troubles de l'humeur, des troubles du sommeil, ou de troubles deficitaires de l'attention
US8580776B2 (en) * 2007-07-10 2013-11-12 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating neurodegenerating diseases
CN102548957A (zh) 2009-07-01 2012-07-04 大日本住友制药株式会社 制备苏-3-(3,4-二羟基苯基)-l-丝氨酸的方法
JP5880913B2 (ja) 2011-05-17 2016-03-09 三郎 佐古田 パーキンソン病の体幹症状(姿勢反射異常)の治療剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE34275B1 (en) * 1969-06-18 1975-03-19 Merck & Co Inc Alpha-hydrazino acids
US3658968A (en) * 1970-06-11 1972-04-25 Merck & Co Inc Composition and method of treatment
DE2305209A1 (de) * 1972-02-14 1973-08-23 Hoffmann La Roche Pharmazeutisches praeparat
AU6889274A (en) * 1973-05-17 1975-11-20 Astra Laekemedel Ab Treatment of neurological disorders
CH580059A5 (fr) * 1973-08-22 1976-09-30 Hoffmann La Roche
US3920728A (en) * 1973-08-22 1975-11-18 Hoffmann La Roche Separation and resolution of isomeric forms of 3-(3,4-dihydroxy-phenyl)-serine
JPS52125630A (en) * 1976-04-14 1977-10-21 Kyowa Hakko Kogyo Co Ltd Antiperkinson drugs containing l-threo-3,4-dihydroxyphenylserine
JPS56104815A (en) * 1980-01-23 1981-08-20 Sumitomo Chem Co Ltd Remedy for peripheral orthostatic hypotension

Also Published As

Publication number Publication date
AU556542B2 (en) 1986-11-06
AU575267B2 (en) 1988-07-21
AU6750187A (en) 1987-04-16
JPH0216284B2 (fr) 1990-04-16
GB2106388B (en) 1986-03-26
BE894451A (fr) 1983-03-21
GB2106388A (en) 1983-04-13
IT8268118A0 (it) 1982-09-21
CH650926A5 (de) 1985-08-30
SE8205404D0 (sv) 1982-09-21
NL189648C (nl) 1993-06-16
DE3235093C2 (fr) 1988-12-29
DE3235093A1 (de) 1983-04-07
SE8205404L (sv) 1983-03-23
SE462781B (sv) 1990-09-03
CA1184501A (fr) 1985-03-26
IT1212668B (it) 1989-11-30
JPS5852219A (ja) 1983-03-28
AU8857882A (en) 1983-03-31
NL189648B (nl) 1993-01-18
FR2513117A1 (fr) 1983-03-25
US4497826A (en) 1985-02-05
NL8203594A (nl) 1983-04-18
NZ201864A (en) 1985-12-13

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