FR2504922B1 - Hydrate de benzoate de lignocaine-benzyle, procede pour sa preparation, procede pour la preparation de benzoate de lignocaine-benzyle, et procede pour denaturer une substance - Google Patents

Hydrate de benzoate de lignocaine-benzyle, procede pour sa preparation, procede pour la preparation de benzoate de lignocaine-benzyle, et procede pour denaturer une substance

Info

Publication number
FR2504922B1
FR2504922B1 FR8207399A FR8207399A FR2504922B1 FR 2504922 B1 FR2504922 B1 FR 2504922B1 FR 8207399 A FR8207399 A FR 8207399A FR 8207399 A FR8207399 A FR 8207399A FR 2504922 B1 FR2504922 B1 FR 2504922B1
Authority
FR
France
Prior art keywords
lignocaine
preparation
benzyl benzoate
denaturation
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8207399A
Other languages
English (en)
Other versions
FR2504922A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2504922A1 publication Critical patent/FR2504922A1/fr
Application granted granted Critical
Publication of FR2504922B1 publication Critical patent/FR2504922B1/fr
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/94Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/02Monohydroxylic acyclic alcohols
    • C07C31/08Ethanol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/04Monocyclic monocarboxylic acids
    • C07C63/06Benzoic acid
    • C07C63/08Salts thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12FRECOVERY OF BY-PRODUCTS OF FERMENTED SOLUTIONS; DENATURED ALCOHOL; PREPARATION THEREOF
    • C12F5/00Preparation of denatured alcohol

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8207399A 1981-04-30 1982-04-29 Hydrate de benzoate de lignocaine-benzyle, procede pour sa preparation, procede pour la preparation de benzoate de lignocaine-benzyle, et procede pour denaturer une substance Expired FR2504922B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8113416 1981-04-30
GB8124864 1981-08-14

Publications (2)

Publication Number Publication Date
FR2504922A1 FR2504922A1 (fr) 1982-11-05
FR2504922B1 true FR2504922B1 (fr) 1985-11-22

Family

ID=26279307

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8207399A Expired FR2504922B1 (fr) 1981-04-30 1982-04-29 Hydrate de benzoate de lignocaine-benzyle, procede pour sa preparation, procede pour la preparation de benzoate de lignocaine-benzyle, et procede pour denaturer une substance

Country Status (10)

Country Link
US (1) US4438046A (fr)
AU (1) AU548251B2 (fr)
CA (1) CA1196928A (fr)
CH (1) CH653010A5 (fr)
DE (1) DE3215987A1 (fr)
FR (1) FR2504922B1 (fr)
GB (1) GB2097791B (fr)
IT (1) IT1147862B (fr)
NL (1) NL8201797A (fr)
SE (1) SE8202713L (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776859A (en) * 1995-11-15 1998-07-07 Nickel; Alfred A. Sodium channel active novel compounds and related processes and bioassay techniques
DE19714580A1 (de) * 1997-04-09 1998-10-15 Haarmann & Reimer Gmbh Vergällungsmittel für Ethanol
US5891919A (en) * 1997-09-19 1999-04-06 Burlington Bio-Medical & Scientific Corp. Denatonium capsaicinate and methods of producing the same
US7011843B2 (en) * 1997-10-01 2006-03-14 Lts Lohmann-Therapie Systeme Ag Method for protecting a human being against health impairment by ingestion of a transdermal therapeutic system
US7632321B2 (en) * 2001-11-01 2009-12-15 Idatech, Llc Fuel processing systems, fuel cell systems, and improved feedstocks therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080326A (en) 1959-06-01 1963-03-05 T & H Smith Ltd Denatured alcohol
US3080327A (en) 1959-11-20 1963-03-05 T & H Smith Ltd Quaternary salts as denaturants for organic substances
GB955309A (en) 1959-11-20 1964-04-15 Edinburgh Pharmaceutical Ind L New quaternary salts and compositions containing them

Also Published As

Publication number Publication date
GB2097791B (en) 1984-08-01
IT1147862B (it) 1986-11-26
IT8248305A0 (it) 1982-04-29
AU8313582A (en) 1982-11-04
CH653010A5 (fr) 1985-12-13
GB2097791A (en) 1982-11-10
DE3215987A1 (de) 1982-12-02
CA1196928A (fr) 1985-11-19
SE8202713L (sv) 1982-10-31
US4438046A (en) 1984-03-20
NL8201797A (nl) 1982-11-16
FR2504922A1 (fr) 1982-11-05
AU548251B2 (en) 1985-12-05

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Legal Events

Date Code Title Description
ST Notification of lapse