FR2466252B2 - - Google Patents

Info

Publication number
FR2466252B2
FR2466252B2 FR7924655A FR7924655A FR2466252B2 FR 2466252 B2 FR2466252 B2 FR 2466252B2 FR 7924655 A FR7924655 A FR 7924655A FR 7924655 A FR7924655 A FR 7924655A FR 2466252 B2 FR2466252 B2 FR 2466252B2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7924655A
Other versions
FR2466252A2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CM Industries SA
Clin Midy
Original Assignee
CM Industries SA
Clin Midy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CM Industries SA, Clin Midy filed Critical CM Industries SA
Priority to FR7924655A priority Critical patent/FR2466252A2/fr
Publication of FR2466252A2 publication Critical patent/FR2466252A2/fr
Application granted granted Critical
Publication of FR2466252B2 publication Critical patent/FR2466252B2/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins
    • A61K47/6819—Plant toxins
    • A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
    • A61K47/6827—Ricin A

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Toxicology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR7924655A 1979-10-03 1979-10-03 Nouveaux produits ayant notamment des proprietes anticancereuses a base de chaine a de la ricine et d'une proteine Granted FR2466252A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7924655A FR2466252A2 (fr) 1979-10-03 1979-10-03 Nouveaux produits ayant notamment des proprietes anticancereuses a base de chaine a de la ricine et d'une proteine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7924655A FR2466252A2 (fr) 1979-10-03 1979-10-03 Nouveaux produits ayant notamment des proprietes anticancereuses a base de chaine a de la ricine et d'une proteine

Publications (2)

Publication Number Publication Date
FR2466252A2 FR2466252A2 (fr) 1981-04-10
FR2466252B2 true FR2466252B2 (fr) 1983-08-12

Family

ID=9230281

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7924655A Granted FR2466252A2 (fr) 1979-10-03 1979-10-03 Nouveaux produits ayant notamment des proprietes anticancereuses a base de chaine a de la ricine et d'une proteine

Country Status (1)

Country Link
FR (1) FR2466252A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2504010B1 (fr) * 1981-04-15 1985-10-25 Sanofi Sa Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation
FR2516794B1 (fr) * 1981-11-20 1985-10-25 Sanofi Sa Nouveaux medicaments anticancereux pour le traitement des leucemies t constitues de la chaine a de la ricine et d'un anticorps monoclonal specifique
FR2522968B1 (fr) * 1982-03-10 1986-03-28 Sanofi Sa Medicament cytotoxique forme de l'association d'a u moins une immunotoxine et de la chloroquine
FR2536997B1 (fr) * 1982-03-11 1987-08-07 Sanofi Sa Medicaments cytotoxiques comportant au moins une immunotoxine et de la methylamine
FR2547731A1 (fr) * 1983-06-27 1984-12-28 Centre Nat Rech Scient Immunotoxine antitumorale, preparations pharmaceutiques la contenant et son utilisation in vitro
FR2566271B1 (fr) * 1984-06-20 1986-11-07 Sanofi Sa Nouveaux conjugues cytotoxiques utilisables en therapeutique et procede d'obtention
US4590071A (en) * 1984-09-25 1986-05-20 Xoma Corporation Human melanoma specific immunotoxins
ATE87318T1 (de) * 1985-11-29 1993-04-15 Consolidated Pharmaceuticals L Ricin-antikoerper-konjugate.
US4981979A (en) * 1987-09-10 1991-01-01 Neorx Corporation Immunoconjugates joined by thioether bonds having reduced toxicity and improved selectivity
EE200000362A (et) * 1997-12-17 2001-12-17 Merck & Co., Inc. Integriini retseptori antagonistid, farmatseutiline kompositsioon ja selle valmistamismeetod

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2319473A1 (de) * 1973-04-17 1974-11-07 Eisai Co Ltd Ricinhaltiges pharmazeutisches material mit antikrebswirkung
DE2456224A1 (de) * 1974-11-28 1976-08-12 Karl Dr Med Theurer Verwendung von nativen antikoerpern oder von antikoerper-fragmenten mit kovalent gebundenen oder konjugierten zytostatisch und/bzw. oder zytotoxisch wirkenden substanzen fuer die krebstherapie
GB1446536A (en) * 1975-02-21 1976-08-18 Yeda Res & Dev Pharmaceutically active compositions

Also Published As

Publication number Publication date
FR2466252A2 (fr) 1981-04-10

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Legal Events

Date Code Title Description
TP Transmission of property