FR2457870A1 - Derives de cephalosporine administrables par voie orale et leur application therapeutique - Google Patents

Derives de cephalosporine administrables par voie orale et leur application therapeutique

Info

Publication number
FR2457870A1
FR2457870A1 FR8012193A FR8012193A FR2457870A1 FR 2457870 A1 FR2457870 A1 FR 2457870A1 FR 8012193 A FR8012193 A FR 8012193A FR 8012193 A FR8012193 A FR 8012193A FR 2457870 A1 FR2457870 A1 FR 2457870A1
Authority
FR
France
Prior art keywords
therapeutic application
cephalosporin derivatives
methoxy
hydroxy
acyloxymethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8012193A
Other languages
English (en)
Inventor
Hideo Nakao
Shinichi Sugawara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP6829179A external-priority patent/JPS55160782A/ja
Priority claimed from JP8421979A external-priority patent/JPS568391A/ja
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of FR2457870A1 publication Critical patent/FR2457870A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

L'INVENTION A POUR OBJET CERTAINS 7-2-(2-AMINO-THIAZOL-4-YL)-2-(HYDROXY OU METHOXY) IMINOACETAMIDO-3-METHYL-3-CEPHEME-4-CARBOXYLATES D'ACYLOXYMETHYLE (ISOMERES SYN) AISEMENT ABSORBES PAR LE TUBE DIGESTIF ET CONVERTIS IN VIVO EN LES ACIDES CARBOXYLIQUES CORRESPONDANTS, QUI ONT DE REMARQUABLES PROPRIETES ANTIBIOTIQUES. CES ESTERS PEUVENT ETRE PREPARES PAR ACYLATION DU 7-AMINODESACETOXYCEPHALOSPORANATE D'ACYLOXYMETHYLE CORRESPONDANT, PAR ESTERIFICATION DE L'ACIDE CORRESPONDANT OU PAR CONVERSION D'UN GROUPE ACYLE INDESIRABLE EN POSITION 7 D'UN COMPOSE DE CEPHALOSPORINE EN LE GROUPE 7-2-(2-AMINOTHIAZOL-4-YL)-2-(HYDROXY OU METHOXY) IMINOACETYLE SOUHAITE.
FR8012193A 1979-06-01 1980-06-02 Derives de cephalosporine administrables par voie orale et leur application therapeutique Withdrawn FR2457870A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6829179A JPS55160782A (en) 1979-06-01 1979-06-01 Cephalosporin compound for oral administration
JP8421979A JPS568391A (en) 1979-07-03 1979-07-03 Cephalosporin compound for oral use

Publications (1)

Publication Number Publication Date
FR2457870A1 true FR2457870A1 (fr) 1980-12-26

Family

ID=26409507

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8012193A Withdrawn FR2457870A1 (fr) 1979-06-01 1980-06-02 Derives de cephalosporine administrables par voie orale et leur application therapeutique

Country Status (6)

Country Link
DE (1) DE3020625A1 (fr)
ES (2) ES8105326A1 (fr)
FR (1) FR2457870A1 (fr)
GB (1) GB2051066A (fr)
IT (1) IT8067851A0 (fr)
NL (1) NL8003186A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2509733A1 (fr) * 1981-07-17 1983-01-21 Hoffmann La Roche Derives de cephalosporine
EP0148007A2 (fr) * 1983-12-26 1985-07-10 Yamanouchi Pharmaceutical Co. Ltd. Dérivés de céphalosporine, leurs médicaments et leur production

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914091A (en) * 1984-04-02 1990-04-03 American Cyanamid Company Esters of cephalosporin derivitives
US4935508A (en) * 1988-08-23 1990-06-19 Bristol-Myers Company Process for cephem prodrug esters

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2509733A1 (fr) * 1981-07-17 1983-01-21 Hoffmann La Roche Derives de cephalosporine
EP0148007A2 (fr) * 1983-12-26 1985-07-10 Yamanouchi Pharmaceutical Co. Ltd. Dérivés de céphalosporine, leurs médicaments et leur production
EP0148007A3 (fr) * 1983-12-26 1986-04-02 Yamanouchi Pharmaceutical Co. Ltd. Dérivés de céphalosporine, leurs médicaments et leur production

Also Published As

Publication number Publication date
GB2051066A (en) 1981-01-14
ES492045A0 (es) 1981-05-16
ES8202559A1 (es) 1982-02-01
DE3020625A1 (de) 1980-12-04
ES499081A0 (es) 1982-02-01
IT8067851A0 (it) 1980-05-30
ES8105326A1 (es) 1981-05-16
NL8003186A (nl) 1980-12-03

Similar Documents

Publication Publication Date Title
FR2445835A1 (fr) Nouvelles cephalosporines, leur procede de preparation et leur application therapeutique
SE8202961L (sv) Cefalosporinderivat och forfarande for deras framstellning
PT87474A (pt) Process for the preparation of pharmaceutical compounds which contain ester 1-acetoxi-ethylic of cefuroxime
FR2387234A1 (fr) Derives de cephalosporine, leur procede de preparation et leurs applications en therapeutique
FR2457870A1 (fr) Derives de cephalosporine administrables par voie orale et leur application therapeutique
PT74511A (fr) Procede de preparation de nouveaux derives des cephalosporines presentant des proprietes antibiotiques
NZ186998A (en) Esters of cefuroxime ((6r,7r)-3-carbamoyloxy-methyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido) ceph-3-em-carboxylic acid syn isomer) and pharmaceutical compositions
NO173736C (no) Analogifremgangsmaate for fremstilling av en terapeutisk aktiv forbindelse bestaaende hovedsaklig av diastereomer (I) av cefalosporinderivater
FR2449093A1 (fr) Nouveaux derives de la cephalosporine, leur preparation et leur application comme medicaments
EP0013732A3 (en) Imidazole derivatives and intermediates, processes for their preparation and pharmaceutical compositions containing these imidazole derivatives
DK508885D0 (da) Esterderivat af antibiotikum l 17046 og fremgangsmaade til fremstillingderaf
FR2677354B1 (fr) Procede pour la preparation d'esters d'acides racemisables.
NO162240C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 7-mandelamid-3-cefem-4-karboksylatderivater.
NO891231L (no) Cefalosporinderivater og fremgangsmaate for fremstilling derav.
EP0122584A3 (fr) Forme cristalline de ceftazidim
FR2365571A1 (fr) Acides 7-acylamino-3-(sulfomethylthiadiazolyl- ou triazolyl-thiomethyl)-3-cepheme-4-carboxyliques, leur procede de preparation et leur application en therapeutique
GB1421526A (en) Penicillins and cephalosporins
FI901520A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten kefeemikarbonyylihappoesterien valmistamiseksi
IT9021053A1 (it) Procedimento per la preparazione di esteri benzidrilici di penicilline
RO89517A (fr) Procede pour la preparation de l'ester ethoxycarbonyloxyethyle de la penicilline g
ITMI912015A1 (it) Procedimento per la preparazione di esteri benzidrilici di penicilline
EP0281092A3 (fr) Dérivés de céphalosporine et procédé pour leur préparation
FR2400025A1 (fr) Esters acetoxyethyliques d'acides ceph-3-eme-4-carboxyliques a activite antibiotique, leur procede de preparation et leur application en therapeutique
IT1217165B (it) Sistema per l'acquisizione di segnali da una pluralita di sensori elettrici
RU93058370A (ru) Новые цефалоспорины с конденсированным пиридинийметилом в 3-м положении

Legal Events

Date Code Title Description
ST Notification of lapse