FR2452482A1 - Tri:fluoro ethyl pyrrolidinyl methyl benzamide(s) - are appetite stimulants prepd. from a benzoic acid and an amino methyl pyrrolidine - Google Patents

Tri:fluoro ethyl pyrrolidinyl methyl benzamide(s) - are appetite stimulants prepd. from a benzoic acid and an amino methyl pyrrolidine

Info

Publication number
FR2452482A1
FR2452482A1 FR7907744A FR7907744A FR2452482A1 FR 2452482 A1 FR2452482 A1 FR 2452482A1 FR 7907744 A FR7907744 A FR 7907744A FR 7907744 A FR7907744 A FR 7907744A FR 2452482 A1 FR2452482 A1 FR 2452482A1
Authority
FR
France
Prior art keywords
benzoic acid
prepd
tri
fluoro ethyl
appetite stimulants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7907744A
Other languages
French (fr)
Other versions
FR2452482B1 (en
Inventor
Jean Pierre Kaplan
Henry Najer
Daniel Obitz
Philippe Manoury
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7907744A priority Critical patent/FR2452482A1/en
Publication of FR2452482A1 publication Critical patent/FR2452482A1/en
Application granted granted Critical
Publication of FR2452482B1 publication Critical patent/FR2452482B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Racemates and optically active isomers of benzamides of formula (I) and their acid addition salts are new. The compounds are prepared by reaction of corresp. benzoic acid deriv. or a functional derivative of with a racemic or optionally active pyrrolidine (III) (where R is -SONR1R2: R1 and R2 are H, 1-4C alkyl, 1-4C alkylthio, or CF3).
FR7907744A 1979-03-28 1979-03-28 Tri:fluoro ethyl pyrrolidinyl methyl benzamide(s) - are appetite stimulants prepd. from a benzoic acid and an amino methyl pyrrolidine Granted FR2452482A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7907744A FR2452482A1 (en) 1979-03-28 1979-03-28 Tri:fluoro ethyl pyrrolidinyl methyl benzamide(s) - are appetite stimulants prepd. from a benzoic acid and an amino methyl pyrrolidine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7907744A FR2452482A1 (en) 1979-03-28 1979-03-28 Tri:fluoro ethyl pyrrolidinyl methyl benzamide(s) - are appetite stimulants prepd. from a benzoic acid and an amino methyl pyrrolidine

Publications (2)

Publication Number Publication Date
FR2452482A1 true FR2452482A1 (en) 1980-10-24
FR2452482B1 FR2452482B1 (en) 1982-01-29

Family

ID=9223643

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7907744A Granted FR2452482A1 (en) 1979-03-28 1979-03-28 Tri:fluoro ethyl pyrrolidinyl methyl benzamide(s) - are appetite stimulants prepd. from a benzoic acid and an amino methyl pyrrolidine

Country Status (1)

Country Link
FR (1) FR2452482A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987007271A1 (en) * 1986-05-22 1987-12-03 Astra Läkemedel Aktiebolag A stereoconservative synthesis of 1-substituted (s)- and (r)-2-aminomethylpyrrolidines and intermediates thereto
US5300660A (en) * 1986-05-22 1994-04-05 Astra Lakemedel Aktiebolag Efficient stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates thereto

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5365875A (en) * 1976-11-24 1978-06-12 Teijin Ltd Preparation of benzenesulfone amide derivs.
FR2393794A2 (en) * 1977-06-06 1979-01-05 Synthelabo Therapeutic 2-methoxy benzamido methyl heterocycle(s) prepn. - from 2-methoxy benzoic ester(s) and amino methyl heterocycle(s)

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5365875A (en) * 1976-11-24 1978-06-12 Teijin Ltd Preparation of benzenesulfone amide derivs.
FR2393794A2 (en) * 1977-06-06 1979-01-05 Synthelabo Therapeutic 2-methoxy benzamido methyl heterocycle(s) prepn. - from 2-methoxy benzoic ester(s) and amino methyl heterocycle(s)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1978 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987007271A1 (en) * 1986-05-22 1987-12-03 Astra Läkemedel Aktiebolag A stereoconservative synthesis of 1-substituted (s)- and (r)-2-aminomethylpyrrolidines and intermediates thereto
EP0253785A1 (en) * 1986-05-22 1988-01-20 Astra Lakemedel Aktiebolag Efficient stereoconservative syntheses of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates therein
US5300660A (en) * 1986-05-22 1994-04-05 Astra Lakemedel Aktiebolag Efficient stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates thereto
US5468876A (en) * 1986-05-22 1995-11-21 Aktiebolaget Astra Intermediates for the stereoconservative synthesis of 1-substituted (S)-and (R)-2-aminomethylpyrrolidines

Also Published As

Publication number Publication date
FR2452482B1 (en) 1982-01-29

Similar Documents

Publication Publication Date Title
SE8200815L (en) CHEMICAL COMPOUNDS FOR USE AS INTERMEDIATE IN THE PRODUCTION OF CERTAIN TRIAZOLIC COMPOUNDS
DE68929330D1 (en) Intermediates for the preparation of derivatives of 4-oxoquinoline-3-carboxylic acid
PT80244A (en) Process for preparation of optically active alpha-arylalkanoic acids and novel intermediates thereof
SE8404019L (en) Ophthalmic anti-inflammatory agents
DE3380350D1 (en) Hydroxyalkynyl-azolyl derivatives, process for their preparation and their use as fungicides
FR2452482A1 (en) Tri:fluoro ethyl pyrrolidinyl methyl benzamide(s) - are appetite stimulants prepd. from a benzoic acid and an amino methyl pyrrolidine
ES522436A0 (en) ANALOGUE PROCEDURE FOR PREPARING ACID (R, S) -5-AMINO-HEPTA-5,6-DIENOIC, ACID (S) -4-AMINO-HEPTA-5,6-DIENOIC OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS.
GB2001053A (en) Insecticidal substituted benzoyl ureas
ATE25383T1 (en) INDOLOQUINOLIZIN DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR THERAPEUTIC APPLICATION.
SE8800846D0 (en) OPTICALLY ACTIVE OXO-ISOINDOLIN DERIVATIVES
ES476030A1 (en) Process for production of optically active bases
ES8503655A1 (en) Novel dihydropyridines.
ATE79875T1 (en) PYRETHROIDS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE FOR COMBATING PESTS, AND PREPARATORY PRODUCTS FOR THE MANUFACTURE OF THE PYRETHROIDS.
ES422085A1 (en) Primary amino acylanilides methods of making the same and use as antiarrhythmic drugs
ATE18208T1 (en) N-(4-HYDROXYPHENYL)ACETIC ACID ESTERS FROM 5BENZOYL-1-METHYLPYRROL-2-ACETIC ACID.
NO885412D0 (en) NEW THERAPEUTIC ACTIVE RELATIONS AND PROCEDURE FOR THEIR PREPARATION.
ATE27955T1 (en) PROCESSES AND INTERMEDIATE PRODUCTS FOR THE PREPARATION OF 2-SUBSTITUTED 4-ACETYL-IMIDAZOLES.
ES8106526A1 (en) Process for the preparation of halogenated 15-hydroxy-E-homoeburnane compounds
JPS55167203A (en) Herbicide
ATE292T1 (en) SPIRO DERIVATIVES OF 3-(3,5-DIHALOGENPHENYL)-OXAZOLIDIN-2-THION-4-ONES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS FUNGICIDES.
ES8100269A1 (en) Procedure for the preparation of substitute 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines. (Machine-translation by Google Translate, not legally binding)
ATE6775T1 (en) ANILIDES, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM.
ES8604174A1 (en) New isoxazoles and process for the preparation thereof
ATE41770T1 (en) N-(2-PYRROLIDINYLMETHYL)BENZAMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE, INTERMEDIATE PRODUCTS AND PHARMACEUTICAL PREPARATION.
GB1513726A (en) Optically-active isomers of alanine derivatives their preparation and their use as herbicides

Legal Events

Date Code Title Description
ST Notification of lapse