FR2452478A1 - Amides d'acide farnesylacetique et leur utilisation en tant qu'agents anti-ulcereux et agents antibacteriens - Google Patents
Amides d'acide farnesylacetique et leur utilisation en tant qu'agents anti-ulcereux et agents antibacteriensInfo
- Publication number
- FR2452478A1 FR2452478A1 FR8005931A FR8005931A FR2452478A1 FR 2452478 A1 FR2452478 A1 FR 2452478A1 FR 8005931 A FR8005931 A FR 8005931A FR 8005931 A FR8005931 A FR 8005931A FR 2452478 A1 FR2452478 A1 FR 2452478A1
- Authority
- FR
- France
- Prior art keywords
- agents
- acid amides
- antibacterial agents
- farnesylacetic acid
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
COMPOSES DE TYPE AMIDE D'ACIDE FARNESYLACETIQUE DE FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE A EST UN RADICAL ALKYLENE D'AU MOINS 2ATOMES DE CARBONE, R EST UN ATOME D'HYDROGENE OU UN RADICAL ALKYLE INFERIEUR, ET R ET R SONT CHACUN, INDEPENDAMMENT, UN ATOME D'HYDROGENE, UN RADICAL ALKYLE, CYCLOALKYLE, ALKENYLE, ARYLE OU ARALKYLE, OU L'UN DE R ET R EST UN GROUPE QUI FORME, AVEC A, UN NOYAU PIPERIDINE CONTENANT EN TANT QU'ELEMENT CONSTITUTIF L'ATOME D'AZOTE SITUE ENTRE EUX, OU ENCORE R ET R, EN COMBINAISON, REPRESENTENT UN GROUPE QUI FORME, AVEC L'ATOME D'AZOTE AUQUEL ILS SONT LIES, UN NOYAU PIPERIDINE, PYRROLIDINE OU PIPERAZINE. CES COMPOSES, AINSI QUE LEURS SELS ACCEPTABLES DU POINT DE VUE PHARMACEUTIQUE, SONT UTILES EN TANT QU'AGENTS ANTIULCEROGENES ET AGENTS ANTIBACTERIENS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3758579A JPS55129255A (en) | 1979-03-28 | 1979-03-28 | Farnesylacetamide compounds or their salts |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2452478A1 true FR2452478A1 (fr) | 1980-10-24 |
FR2452478B1 FR2452478B1 (fr) | 1981-10-23 |
Family
ID=12501607
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8005931A Granted FR2452478A1 (fr) | 1979-03-28 | 1980-03-17 | Amides d'acide farnesylacetique et leur utilisation en tant qu'agents anti-ulcereux et agents antibacteriens |
Country Status (7)
Country | Link |
---|---|
US (1) | US4303588A (fr) |
JP (1) | JPS55129255A (fr) |
CH (1) | CH644353A5 (fr) |
DE (1) | DE3011504C2 (fr) |
FR (1) | FR2452478A1 (fr) |
GB (1) | GB2046745B (fr) |
IT (1) | IT1194641B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0875501A2 (fr) * | 1997-04-04 | 1998-11-04 | Shiseido Company Limited | Dérivé d'alkylène-diamines, médicament antiulcéreux et antibactérien |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2025490C (fr) * | 1989-09-22 | 2003-09-16 | James R. Mccarthy | Alkyl piperidines subtituees et leur utilisation comme inhibiteurs de la synthese du cholesterol |
US5217979A (en) * | 1989-09-22 | 1993-06-08 | Merrell Dow Pharmaceuticals Inc. | Substituted alkyl piperidines |
US5350758A (en) * | 1992-07-08 | 1994-09-27 | Merrell Dow Pharmaceuticals Inc. | Piperidyl sulfonamides and sulfoxamides as inhibitors of cholesterol biosynthesis |
US5756475A (en) * | 1996-01-31 | 1998-05-26 | Nisshin Flour Milling Co., Ltd. | Isoprene derivatives |
US7053127B1 (en) * | 2002-09-16 | 2006-05-30 | Nalco Company | Quaternized amido cyclic amine surfactant |
US20050025823A1 (en) * | 2003-07-29 | 2005-02-03 | Fong Andy A.T. | Methods of use of herbal compositions |
US20080145409A1 (en) * | 2006-12-19 | 2008-06-19 | Min Chang Huang | Composition for the treatment and prevention of peptic ulcer |
MX357352B (es) * | 2011-02-23 | 2018-07-05 | Univ Aix Marseille | Uso de derivados poliaminoisoprenilo en un tratamiento antibiotico o antiseptico. |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB833655A (en) * | 1955-05-05 | 1960-04-27 | Joseph Nichols | Amides |
FR1266607A (fr) * | 1960-06-02 | 1961-07-17 | Du Pont | Additif pour carburants |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH122293A (de) * | 1925-09-02 | 1927-09-01 | Chem Ind Basel | Verfahren zur Darstellung einer neuen Gallensäureverbindung. |
BE578257A (fr) * | 1958-04-30 | |||
US3646036A (en) * | 1970-03-30 | 1972-02-29 | Searle & Co | 1-farnesylacetyl-4-hydroxyalkyl-piperazines |
-
1979
- 1979-03-28 JP JP3758579A patent/JPS55129255A/ja active Granted
-
1980
- 1980-03-17 FR FR8005931A patent/FR2452478A1/fr active Granted
- 1980-03-21 US US06/132,408 patent/US4303588A/en not_active Expired - Lifetime
- 1980-03-21 GB GB8009647A patent/GB2046745B/en not_active Expired
- 1980-03-25 DE DE3011504A patent/DE3011504C2/de not_active Expired
- 1980-03-27 CH CH242780A patent/CH644353A5/fr not_active IP Right Cessation
- 1980-03-27 IT IT20973/80A patent/IT1194641B/it active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB833655A (en) * | 1955-05-05 | 1960-04-27 | Joseph Nichols | Amides |
FR1266607A (fr) * | 1960-06-02 | 1961-07-17 | Du Pont | Additif pour carburants |
Non-Patent Citations (2)
Title |
---|
CA1965 * |
CA1969 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0875501A2 (fr) * | 1997-04-04 | 1998-11-04 | Shiseido Company Limited | Dérivé d'alkylène-diamines, médicament antiulcéreux et antibactérien |
EP0875501A3 (fr) * | 1997-04-04 | 1999-01-13 | Shiseido Company Limited | Dérivé d'alkylène-diamines, médicament antiulcéreux et antibactérien |
US6001880A (en) * | 1997-04-04 | 1999-12-14 | Shiseido Co., Ltd. | Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug |
Also Published As
Publication number | Publication date |
---|---|
GB2046745B (en) | 1983-05-05 |
IT1194641B (it) | 1988-09-22 |
JPS6223742B2 (fr) | 1987-05-25 |
GB2046745A (en) | 1980-11-19 |
JPS55129255A (en) | 1980-10-06 |
FR2452478B1 (fr) | 1981-10-23 |
CH644353A5 (fr) | 1984-07-31 |
US4303588A (en) | 1981-12-01 |
DE3011504C2 (de) | 1983-05-19 |
IT8020973A0 (it) | 1980-03-27 |
DE3011504A1 (de) | 1980-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |