FR2434167A1 - Derives de l'hexahydro-1,2,3,3a,8,8a pyrrolo indole (2,3,-b) - Google Patents

Derives de l'hexahydro-1,2,3,3a,8,8a pyrrolo indole (2,3,-b)

Info

Publication number
FR2434167A1
FR2434167A1 FR7826975A FR7826975A FR2434167A1 FR 2434167 A1 FR2434167 A1 FR 2434167A1 FR 7826975 A FR7826975 A FR 7826975A FR 7826975 A FR7826975 A FR 7826975A FR 2434167 A1 FR2434167 A1 FR 2434167A1
Authority
FR
France
Prior art keywords
hexahydro
derivatives
pyrrolo
indole
pyrrolo indole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7826975A
Other languages
English (en)
Other versions
FR2434167B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universita degli Studi di Firenze
Original Assignee
Universita degli Studi di Firenze
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universita degli Studi di Firenze filed Critical Universita degli Studi di Firenze
Publication of FR2434167A1 publication Critical patent/FR2434167A1/fr
Application granted granted Critical
Publication of FR2434167B1 publication Critical patent/FR2434167B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Nouveaux dérivés de l'hexahydro-1,2,3,3a,8,8a pyrrolo-indole Ø2,3-bõ répondant à la formule suivante :
FR7826975A 1977-09-20 1978-09-20 Derives de l'hexahydro-1,2,3,3a,8,8a pyrrolo indole (2,3,-b) Granted FR2434167A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT09574/77A IT1109003B (it) 1977-09-20 1977-09-20 Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo

Publications (2)

Publication Number Publication Date
FR2434167A1 true FR2434167A1 (fr) 1980-03-21
FR2434167B1 FR2434167B1 (fr) 1983-03-18

Family

ID=11132370

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7826975A Granted FR2434167A1 (fr) 1977-09-20 1978-09-20 Derives de l'hexahydro-1,2,3,3a,8,8a pyrrolo indole (2,3,-b)

Country Status (7)

Country Link
JP (1) JPS54112897A (fr)
AR (1) AR222311A1 (fr)
CA (1) CA1125657A (fr)
DE (1) DE2839279A1 (fr)
FR (1) FR2434167A1 (fr)
GB (1) GB2005259B (fr)
IT (1) IT1109003B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
GB8616089D0 (en) * 1986-07-02 1986-08-06 Univ Manchester Organic compounds
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
IT1225462B (it) * 1987-04-03 1990-11-14 Mediolanum Farmaceutici Srl Sali organici di derivati della fisostigmina
AT400331B (de) * 1987-05-15 1995-12-27 Hoechst Roussel Pharma 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo (2,3-b)indole, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5260452A (en) * 1989-11-03 1993-11-09 Hoechst-Roussel Pharmaceuticals Inc. 4- and 6-carbamates related to physostigmine and intermediates for the preparation thereof
US5206260A (en) * 1991-11-07 1993-04-27 Merck & Co., Inc. Hexahydropyrrolo[2,3-b]indole derivatives
GB9205670D0 (en) * 1992-03-16 1992-04-29 Indena Spa New derivatives of physostigmine,their use and pharmaceutical formulations containing them
EP1023297A1 (fr) 1997-10-10 2000-08-02 CHIESI FARMACEUTICI S.p.A. Procede de preparation de derives aminocarbonyle de geneseroline ayant une activite anticolinesterase selective dans le cerveau
US6495700B1 (en) * 2002-01-09 2002-12-17 Axonyx, Inc. Process for producing phenserine and its analog

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EXBK/35 *
EXBK/70 *

Also Published As

Publication number Publication date
AR222311A1 (es) 1981-05-15
GB2005259B (en) 1982-06-23
JPS54112897A (en) 1979-09-04
DE2839279A1 (de) 1979-03-29
IT1109003B (it) 1985-12-16
GB2005259A (en) 1979-04-19
CA1125657A (fr) 1982-06-15
FR2434167B1 (fr) 1983-03-18

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Legal Events

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ST Notification of lapse