FR23C1036I1 - ANTIBODIES THAT BIND TO IL-23 - Google Patents

ANTIBODIES THAT BIND TO IL-23

Info

Publication number
FR23C1036I1
FR23C1036I1 FR23C1036C FR23C1036C FR23C1036I1 FR 23C1036 I1 FR23C1036 I1 FR 23C1036I1 FR 23C1036 C FR23C1036 C FR 23C1036C FR 23C1036 C FR23C1036 C FR 23C1036C FR 23C1036 I1 FR23C1036 I1 FR 23C1036I1
Authority
FR
France
Prior art keywords
antibodies
bind
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR23C1036C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR23C1036I1 publication Critical patent/FR23C1036I1/en
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
FR23C1036C 2013-03-08 2023-10-13 ANTIBODIES THAT BIND TO IL-23 Active FR23C1036I1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361774732P 2013-03-08 2013-03-08
PCT/US2014/020064 WO2014137962A1 (en) 2013-03-08 2014-03-04 Antibodies that bind il-23

Publications (1)

Publication Number Publication Date
FR23C1036I1 true FR23C1036I1 (en) 2023-12-08

Family

ID=51488096

Family Applications (1)

Application Number Title Priority Date Filing Date
FR23C1036C Active FR23C1036I1 (en) 2013-03-08 2023-10-13 ANTIBODIES THAT BIND TO IL-23

Country Status (40)

Country Link
US (3) US9023358B2 (en)
EP (3) EP3789037A1 (en)
JP (1) JP6096938B2 (en)
KR (2) KR20170103037A (en)
CN (1) CN105307681B (en)
AP (1) AP2015008708A0 (en)
AR (1) AR094877A1 (en)
AU (1) AU2014226094B2 (en)
BR (1) BR112015019611B1 (en)
CA (1) CA2901462C (en)
CL (1) CL2015002388A1 (en)
CY (1) CY1123589T1 (en)
DK (1) DK2964258T3 (en)
EA (1) EA031524B1 (en)
EC (1) ECSP15038626A (en)
ES (1) ES2822662T3 (en)
FI (1) FIC20230030I1 (en)
FR (1) FR23C1036I1 (en)
HK (1) HK1212252A1 (en)
HR (1) HRP20201633T1 (en)
HU (2) HUE051357T2 (en)
IL (2) IL240731B (en)
JO (1) JOP20140049B1 (en)
LT (1) LT2964258T (en)
MA (1) MA38382A1 (en)
MX (1) MX370396B (en)
MY (1) MY171226A (en)
NL (1) NL301247I2 (en)
PE (1) PE20151529A1 (en)
PH (1) PH12015501994A1 (en)
PL (1) PL2964258T3 (en)
PT (1) PT2964258T (en)
RS (1) RS60928B1 (en)
SG (1) SG11201507176VA (en)
SI (1) SI2964258T1 (en)
TN (1) TN2015000348A1 (en)
TW (1) TWI636063B (en)
UA (1) UA123198C2 (en)
WO (1) WO2014137962A1 (en)
ZA (1) ZA201505285B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR102417A1 (en) * 2014-11-05 2017-03-01 Lilly Co Eli ANTI-TNF- / ANTI-IL-23 BIESPECTIFIC ANTIBODIES
CN108135983A (en) * 2015-10-30 2018-06-08 伊莱利利公司 Anti- CGRP/anti-il-23 bispecific antibody and application thereof
TW201902926A (en) 2017-05-03 2019-01-16 美商美國禮來大藥廠 anti-CGRP/anti-IL-23 bispecific antibody and use thereof
TWI744617B (en) 2018-03-30 2021-11-01 美商美國禮來大藥廠 Methods of treating ulcerative colitis
TWI808397B (en) 2018-09-11 2023-07-11 美商美國禮來大藥廠 Methods of treating psoriasis
TW202103734A (en) 2019-04-22 2021-02-01 美商美國禮來大藥廠 Methods of treating crohn’s disease
MX2022004311A (en) 2019-10-15 2022-05-10 Lilly Co Eli Recombinantly engineered, lipase/esterase-deficient mammalian cell lines.
KR20220143005A (en) 2019-12-20 2022-10-24 노바록 바이오테라퓨틱스 리미티드 Anti-interleukin-23 P19 antibodies and methods of use thereof
CN112807428A (en) * 2020-06-12 2021-05-18 江苏荃信生物医药有限公司 Pharmaceutical composition comprising anti-human interleukin 23 monoclonal antibody
WO2022041390A1 (en) * 2020-08-28 2022-03-03 江苏荃信生物医药股份有限公司 Low viscosity liquid formulation comprising high concentration anti-human interleukin 23 monoclonal antibody, and preparation method therefor
TW202224702A (en) 2020-09-10 2022-07-01 美商美國禮來大藥廠 Therapeutic antibody formulations
CA3219846A1 (en) 2021-05-28 2022-12-01 Venkatesh Krishnan Anti-il-23p19 antibody regulation of genes involved in ulcerative colitis
CN113698480B (en) * 2021-09-18 2022-07-01 东大生物技术(苏州)有限公司 Group of IL-23 monoclonal antibodies and medical application thereof
WO2023056417A1 (en) 2021-09-30 2023-04-06 Eli Lilly And Company Anti-il-23p19 antibody regulation of genes involved in bowel urgency in ulcerative colitis
WO2024077113A1 (en) 2022-10-06 2024-04-11 Eli Lilly And Company Methods of treating fatigue in ulcerative colitis

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060284A (en) 1997-07-25 2000-05-09 Schering Corporation DNA encoding interleukin-B30
US7090847B1 (en) 1999-09-09 2006-08-15 Schering Corporation Mammalian cytokines; related reagents and methods
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
DK1601694T3 (en) 2003-03-10 2009-12-14 Schering Corp Uses of IL23 antagonists, related reagents
US8003108B2 (en) * 2005-05-03 2011-08-23 Amgen Inc. Sclerostin epitopes
TR201902033T4 (en) * 2005-06-30 2019-03-21 Janssen Biotech Inc Anti-IL-23 antibodies, compositions, methods and uses.
EA013506B1 (en) * 2005-08-25 2010-06-30 Эли Лилли Энд Компани Anti-il-23 antibodies
CN101248088A (en) * 2005-08-25 2008-08-20 伊莱利利公司 Anit-il-23 antibiodies
US7807160B2 (en) 2005-08-31 2010-10-05 Schering Corporation Engineered anti-IL-23 antibodies
MX2008008621A (en) * 2005-12-29 2008-11-27 Centocor Inc Human anti-il-23 antibodies, compositions, methods and uses.
EP2064242A1 (en) * 2007-02-23 2009-06-03 Schering Corporation Engineered anti-il-23p19 antibodies
HUE042172T2 (en) * 2007-02-23 2019-06-28 Merck Sharp & Dohme Engineered anti-il-23p19 antibodies
MY149129A (en) * 2007-03-20 2013-07-15 Lilly Co Eli Anti-sclerostin antibodies
EP2144628B1 (en) 2007-05-08 2012-10-17 Genentech, Inc. Cysteine engineered anti-muc16 antibodies and antibody drug conjugates
WO2009082624A2 (en) * 2007-12-10 2009-07-02 Zymogenetics, Inc. Antagonists of il-17a, il-17f, and il-23 and methods of using the same
EP2435480A1 (en) * 2009-05-27 2012-04-04 Ablynx N.V. Biparatopic protein constructs directed against il-23
CA3017116A1 (en) * 2010-11-04 2012-05-10 Boehringer Ingelheim International Gmbh Anti-il-23 antibodies
JP5987053B2 (en) * 2011-05-12 2016-09-06 ジェネンテック, インコーポレイテッド Multiple reaction monitoring LC-MS / MS method for detecting therapeutic antibodies in animal samples using framework signature peptides

Also Published As

Publication number Publication date
NL301247I1 (en) 2023-10-11
EP2964258A4 (en) 2016-10-12
KR101775115B1 (en) 2017-09-05
US9023358B2 (en) 2015-05-05
HRP20201633T1 (en) 2020-12-25
US20140255422A1 (en) 2014-09-11
ES2822662T3 (en) 2021-05-04
CA2901462A1 (en) 2014-09-12
RS60928B1 (en) 2020-11-30
US20150232552A1 (en) 2015-08-20
IL272042B (en) 2021-07-29
BR112015019611B1 (en) 2023-05-02
JP2016510744A (en) 2016-04-11
HUE051357T2 (en) 2021-03-01
CN105307681A (en) 2016-02-03
KR20150113202A (en) 2015-10-07
PT2964258T (en) 2020-11-06
NL301247I2 (en) 2023-11-01
TN2015000348A1 (en) 2017-01-03
CL2015002388A1 (en) 2016-03-04
CN105307681B (en) 2018-06-26
UA123198C2 (en) 2021-03-03
TWI636063B (en) 2018-09-21
PL2964258T3 (en) 2021-02-08
EP4311558A2 (en) 2024-01-31
IL240731B (en) 2020-01-30
CY1123589T1 (en) 2022-03-24
LT2964258T (en) 2020-10-12
TW201520225A (en) 2015-06-01
SI2964258T1 (en) 2020-10-30
AU2014226094A1 (en) 2015-08-27
IL272042A (en) 2020-02-27
EP2964258A1 (en) 2016-01-13
MX370396B (en) 2019-12-11
MY171226A (en) 2019-10-03
EA031524B1 (en) 2019-01-31
HUS2300036I1 (en) 2023-11-28
EP3789037A1 (en) 2021-03-10
EA201591368A1 (en) 2015-12-30
FIC20230030I1 (en) 2023-10-03
DK2964258T3 (en) 2020-09-14
CA2901462C (en) 2017-07-25
AR094877A1 (en) 2015-09-02
WO2014137962A1 (en) 2014-09-12
AU2014226094B2 (en) 2016-06-23
NZ711147A (en) 2021-03-26
HK1212252A1 (en) 2016-06-10
SG11201507176VA (en) 2015-10-29
MX2015011959A (en) 2016-04-07
EP2964258B1 (en) 2020-09-02
MA38382A1 (en) 2017-11-30
ZA201505285B (en) 2017-11-29
US9688753B2 (en) 2017-06-27
PE20151529A1 (en) 2015-10-28
ECSP15038626A (en) 2015-11-30
US20170275356A1 (en) 2017-09-28
KR20170103037A (en) 2017-09-12
IL240731A0 (en) 2015-10-29
BR112015019611A2 (en) 2017-08-22
PH12015501994A1 (en) 2016-01-11
EP4311558A3 (en) 2024-04-10
JP6096938B2 (en) 2017-03-15
JOP20140049B1 (en) 2021-08-17
AP2015008708A0 (en) 2015-09-30

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