FR2399431A1 - Derives du thiophene et procede pour leur preparation - Google Patents

Derives du thiophene et procede pour leur preparation

Info

Publication number
FR2399431A1
FR2399431A1 FR7823096A FR7823096A FR2399431A1 FR 2399431 A1 FR2399431 A1 FR 2399431A1 FR 7823096 A FR7823096 A FR 7823096A FR 7823096 A FR7823096 A FR 7823096A FR 2399431 A1 FR2399431 A1 FR 2399431A1
Authority
FR
France
Prior art keywords
preparation
thiophene derivatives
thiophene
derivatives
biotin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7823096A
Other languages
English (en)
Inventor
Enrico Guiseppe Baggiolini
Si Lin Lee
Milan Radoje Uskokovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2399431A1 publication Critical patent/FR2399431A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne la synthèse de la biotine et des intermédiaires de synthèse. Il s'agit notamment de composés de formule générale :
FR7823096A 1977-08-05 1978-08-04 Derives du thiophene et procede pour leur preparation Withdrawn FR2399431A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/822,119 US4130713A (en) 1977-08-05 1977-08-05 Biotin intermediates

Publications (1)

Publication Number Publication Date
FR2399431A1 true FR2399431A1 (fr) 1979-03-02

Family

ID=25235192

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7823096A Withdrawn FR2399431A1 (fr) 1977-08-05 1978-08-04 Derives du thiophene et procede pour leur preparation

Country Status (5)

Country Link
US (1) US4130713A (fr)
JP (1) JPS5448785A (fr)
DE (1) DE2833888A1 (fr)
FR (1) FR2399431A1 (fr)
GB (1) GB2003146A (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337345A (en) * 1977-08-05 1982-06-29 Hoffmann-La Roche Inc. Preparation of biotin via thieno [3,2c] isoxazoles
US4245104A (en) * 1978-12-01 1981-01-13 Hoffmann-La Roche Inc. Isoxazolines and isoxazolidines
US4247704A (en) * 1979-05-29 1981-01-27 Hoffmann-La Roche Inc. Hexahydro thieno imadazole intermediates for the synthesis of biotin
US4284557A (en) * 1979-05-29 1981-08-18 Hoffmann-La Roche Inc. Intermediate racemates for the preparation of biotin and a process for their preparation
US4320056A (en) * 1980-05-15 1982-03-16 Hoffmann-La Roche Inc. Certain thia-diazatricyclo[3,3,3,08,11 ]tridecanes, and their preparation
US4382031A (en) * 1981-03-12 1983-05-03 Hoffmann-La Roche Inc. Intermediates for the preparation of biotin
US4581459A (en) * 1982-05-17 1986-04-08 Pfizer Inc. Process for the preparation of biotin
US4533747A (en) * 1983-03-07 1985-08-06 Smithkline Beckman Corporation Leukotriene antagonists intermediates
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
AU6886791A (en) * 1989-11-13 1991-06-13 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
US20050159602A1 (en) * 2004-01-16 2005-07-21 Labeltek Inc. Method for synthesizing chiral bicyclic thiazolidine hydantoin
CN109503620B (zh) * 2018-12-25 2020-10-16 浙江新和成股份有限公司 5-(2-氧代四氢噻吩并咪唑-4(2h)-烯基)戊酸类化合物的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2489237A (en) * 1948-06-08 1949-11-22 Hoffmann La Roche 3, 4-(2'-keto-imidazolido)-2-omega-hydroxypentyl-thiophanes
BE759513A (fr) * 1969-11-29 1971-05-27 Hoffmann La Roche Thiolactone

Also Published As

Publication number Publication date
JPS5448785A (en) 1979-04-17
GB2003146A (en) 1979-03-07
US4130713A (en) 1978-12-19
DE2833888A1 (de) 1979-02-22

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Legal Events

Date Code Title Description
ST Notification of lapse