FR2390448A1 - Derives azido d'acide penicillanique utiles dans la preparation de medicaments - Google Patents
Derives azido d'acide penicillanique utiles dans la preparation de medicamentsInfo
- Publication number
- FR2390448A1 FR2390448A1 FR7824400A FR7824400A FR2390448A1 FR 2390448 A1 FR2390448 A1 FR 2390448A1 FR 7824400 A FR7824400 A FR 7824400A FR 7824400 A FR7824400 A FR 7824400A FR 2390448 A1 FR2390448 A1 FR 2390448A1
- Authority
- FR
- France
- Prior art keywords
- preparation
- medicinal products
- penicillanic acid
- acid useful
- azido derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Composés de formule :
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB27107/76A GB1585165A (en) | 1976-06-29 | 1976-06-29 | Derivatives of 6-amidino penicillanic acid |
GB3133176 | 1976-07-27 | ||
GB543677 | 1977-02-09 | ||
GB634877 | 1977-02-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2390448A1 true FR2390448A1 (fr) | 1978-12-08 |
FR2390448B1 FR2390448B1 (fr) | 1982-01-15 |
Family
ID=27447448
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7719868A Granted FR2356651A1 (fr) | 1976-06-29 | 1977-06-28 | Nouveaux derives d'acide penicillanique et leur utilisation therapeutique |
FR7824401A Granted FR2390433A1 (fr) | 1976-06-29 | 1978-08-22 | Composes utiles pour la preparation de derives d'acide penicillanique |
FR7824400A Granted FR2390448A1 (fr) | 1976-06-29 | 1978-08-22 | Derives azido d'acide penicillanique utiles dans la preparation de medicaments |
FR7824402A Granted FR2390434A1 (fr) | 1976-06-29 | 1978-08-22 | Composes de depart pour la preparation de derives d'acide penicillanique |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7719868A Granted FR2356651A1 (fr) | 1976-06-29 | 1977-06-28 | Nouveaux derives d'acide penicillanique et leur utilisation therapeutique |
FR7824401A Granted FR2390433A1 (fr) | 1976-06-29 | 1978-08-22 | Composes utiles pour la preparation de derives d'acide penicillanique |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7824402A Granted FR2390434A1 (fr) | 1976-06-29 | 1978-08-22 | Composes de depart pour la preparation de derives d'acide penicillanique |
Country Status (24)
Country | Link |
---|---|
US (1) | US4229443A (fr) |
JP (1) | JPS5325594A (fr) |
AU (1) | AU2631977A (fr) |
BE (1) | BE856278A (fr) |
CA (1) | CA1104126A (fr) |
DD (1) | DD132663A5 (fr) |
DE (1) | DE2728588A1 (fr) |
DK (1) | DK286777A (fr) |
ES (1) | ES460098A1 (fr) |
FI (1) | FI771989A (fr) |
FR (4) | FR2356651A1 (fr) |
GB (1) | GB1585165A (fr) |
GR (1) | GR63588B (fr) |
IE (1) | IE45439B1 (fr) |
IL (1) | IL52280A (fr) |
IT (1) | IT1083653B (fr) |
LU (1) | LU77644A1 (fr) |
NL (1) | NL7707152A (fr) |
NZ (1) | NZ184351A (fr) |
PH (1) | PH14356A (fr) |
PT (1) | PT66726B (fr) |
RO (1) | RO71768A (fr) |
SE (1) | SE7707462L (fr) |
YU (1) | YU153177A (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU503489B2 (en) * | 1975-10-13 | 1979-09-06 | Beecham Group Limited | Substituted aminodeoxy clavulanic acid |
US4345071A (en) * | 1976-06-29 | 1982-08-17 | Leo Pharmaceutical Products, Ltd. A/S | Derivatives of penicillanic acid |
LU77362A1 (fr) * | 1977-05-17 | 1979-01-19 | ||
IL54859A (en) * | 1977-06-21 | 1982-01-31 | Rech Applications Therap | Derivatives of amidinopenicillanic acid,their production and pharmaceutical compositions containing them |
EP0003254B1 (fr) * | 1978-01-26 | 1984-03-28 | Beecham Group Plc | Dérivés de l'acide clavulanique, procédé pour leur préparation et compositions les contenant |
EP0007753B1 (fr) * | 1978-08-02 | 1982-08-25 | Beecham Group Plc | Agents antibactériens de bêta-lactame, un procédé pour leur préparation et compositions pharmaceutiques les contenant |
US4343807A (en) * | 1979-09-27 | 1982-08-10 | Beecham Group Limited | Derivatives of clavulanic acid, a process for their preparation and their use |
US4426389A (en) | 1979-09-27 | 1984-01-17 | Beecham Group Limited | Derivatives of clavulanic acid, a process for their preparation and their use |
US4387051A (en) * | 1979-10-29 | 1983-06-07 | Beecham Group Limited | β-Lactam antibiotics, their preparation and their use in pharmaceutical compositions |
EP0048096A1 (fr) * | 1980-09-13 | 1982-03-24 | Beecham Group Plc | Agents antibactériens à cycle bêta-lactame |
US4562182A (en) * | 1980-12-23 | 1985-12-31 | Beecham Group P.L.C. | Compounds containing beta-lactams |
US4537969A (en) * | 1982-03-18 | 1985-08-27 | Hoffmann-La Roche Inc. | Imidazole derivatives |
US4605744A (en) * | 1982-03-18 | 1986-08-12 | Hoffmann-La Roche Inc. | Imidazole derivatives |
US4431653A (en) * | 1982-03-18 | 1984-02-14 | Hoffmann-La Roche Inc. | Penicillanic acid derivatives |
EP0148283A1 (fr) * | 1983-12-20 | 1985-07-17 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Dérivés d'acide pénicillanique |
US5159077A (en) * | 1989-07-21 | 1992-10-27 | Hoffmann-La Roche Inc. | Penam antibacterial compounds |
US5162523A (en) * | 1989-07-21 | 1992-11-10 | Hoffmann-La Roche Inc. | Cephalosporin antibacterial compounds |
CN100384857C (zh) * | 2003-11-28 | 2008-04-30 | 浙江永宁制药厂 | 耐β-内酰胺酶的头孢菌素酯化合物及其盐 |
US10351549B2 (en) | 2015-07-29 | 2019-07-16 | Laboratorios Del Dr. Esteve S.A. | Amide derivatives having multimodal activity against pain |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB991509A (en) * | 1963-10-15 | 1965-05-12 | Parke Davis & Co | Aminoalkylpiperidinoalkyl-ª‡-naphthylamines |
FR1516741A (fr) * | 1965-03-19 | 1968-02-05 | American Cyanamid Co | Procédé de préparation d'alkylènepipéridines substituées |
GB1250719A (fr) * | 1969-03-19 | 1971-10-20 | ||
US3957764A (en) * | 1969-11-11 | 1976-05-18 | Lovens Kemiske Fabrik Produktionsaktieselskab | 6-aminopenicillanic acid derivatives |
US3755588A (en) * | 1970-11-04 | 1973-08-28 | Leo Pharm Prod Ltd | Penicillanic acid in dosage unit form |
GB1315566A (en) * | 1970-11-06 | 1973-05-02 | Leo Pharm Prod Ltd | Penicillanic acid derivatives |
GB1427139A (en) * | 1972-03-13 | 1976-03-10 | Astra Laekemedel Ab | Penicillins |
DE2515146A1 (de) * | 1975-04-08 | 1976-10-21 | Bayer Ag | Carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1976
- 1976-06-29 GB GB27107/76A patent/GB1585165A/en not_active Expired
-
1977
- 1977-06-07 IE IE1163/77A patent/IE45439B1/en unknown
- 1977-06-08 IL IL52280A patent/IL52280A/xx unknown
- 1977-06-08 PH PH19879A patent/PH14356A/en unknown
- 1977-06-09 CA CA280,167A patent/CA1104126A/fr not_active Expired
- 1977-06-09 NZ NZ184351A patent/NZ184351A/xx unknown
- 1977-06-14 US US05/806,358 patent/US4229443A/en not_active Expired - Lifetime
- 1977-06-20 YU YU01531/77A patent/YU153177A/xx unknown
- 1977-06-22 AU AU26319/77A patent/AU2631977A/en active Pending
- 1977-06-23 ES ES460098A patent/ES460098A1/es not_active Expired
- 1977-06-24 DE DE19772728588 patent/DE2728588A1/de not_active Withdrawn
- 1977-06-27 DD DD7700199728A patent/DD132663A5/xx unknown
- 1977-06-27 FI FI771989A patent/FI771989A/fi not_active Application Discontinuation
- 1977-06-27 PT PT66726A patent/PT66726B/pt unknown
- 1977-06-28 LU LU77644A patent/LU77644A1/xx unknown
- 1977-06-28 GR GR53824A patent/GR63588B/el unknown
- 1977-06-28 FR FR7719868A patent/FR2356651A1/fr active Granted
- 1977-06-28 IT IT68497/77A patent/IT1083653B/it active
- 1977-06-28 NL NL7707152A patent/NL7707152A/xx not_active Application Discontinuation
- 1977-06-28 JP JP7623377A patent/JPS5325594A/ja active Pending
- 1977-06-28 RO RO7790849A patent/RO71768A/fr unknown
- 1977-06-28 DK DK286777A patent/DK286777A/da unknown
- 1977-06-28 SE SE7707462A patent/SE7707462L/xx not_active Application Discontinuation
- 1977-06-29 BE BE178917A patent/BE856278A/fr unknown
-
1978
- 1978-08-22 FR FR7824401A patent/FR2390433A1/fr active Granted
- 1978-08-22 FR FR7824400A patent/FR2390448A1/fr active Granted
- 1978-08-22 FR FR7824402A patent/FR2390434A1/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
BE856278A (fr) | 1977-12-29 |
NL7707152A (nl) | 1978-01-02 |
DD132663A5 (de) | 1978-10-18 |
FR2390448B1 (fr) | 1982-01-15 |
PT66726B (en) | 1978-11-22 |
FR2390434A1 (fr) | 1978-12-08 |
PT66726A (en) | 1977-07-01 |
IT1083653B (it) | 1985-05-25 |
FI771989A (fr) | 1977-12-30 |
ES460098A1 (es) | 1978-07-16 |
FR2390433A1 (fr) | 1978-12-08 |
IL52280A0 (en) | 1977-08-31 |
DE2728588A1 (de) | 1978-01-05 |
IE45439B1 (en) | 1982-08-25 |
JPS5325594A (en) | 1978-03-09 |
IL52280A (en) | 1981-07-31 |
IE45439L (en) | 1977-12-29 |
PH14356A (en) | 1981-06-03 |
FR2390433B1 (fr) | 1982-07-09 |
FR2356651B1 (fr) | 1982-03-12 |
NZ184351A (en) | 1980-04-28 |
SE7707462L (sv) | 1977-12-30 |
CA1104126A (fr) | 1981-06-30 |
AU2631977A (en) | 1979-01-04 |
RO71768A (fr) | 1982-05-10 |
GR63588B (en) | 1979-11-26 |
FR2390434B1 (fr) | 1982-09-10 |
US4229443A (en) | 1980-10-21 |
YU153177A (en) | 1982-10-31 |
LU77644A1 (fr) | 1978-02-13 |
GB1585165A (en) | 1981-02-25 |
FR2356651A1 (fr) | 1978-01-27 |
DK286777A (da) | 1977-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |