FR2388277A1 - Procede et appareil de numeration des leucocytes et des plaquettes dans le sang - Google Patents
Procede et appareil de numeration des leucocytes et des plaquettes dans le sangInfo
- Publication number
- FR2388277A1 FR2388277A1 FR7811372A FR7811372A FR2388277A1 FR 2388277 A1 FR2388277 A1 FR 2388277A1 FR 7811372 A FR7811372 A FR 7811372A FR 7811372 A FR7811372 A FR 7811372A FR 2388277 A1 FR2388277 A1 FR 2388277A1
- Authority
- FR
- France
- Prior art keywords
- blood
- leucocytes
- numbering
- plates
- blood sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004369 blood Anatomy 0.000 title abstract 3
- 239000008280 blood Substances 0.000 title abstract 3
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 229940127219 anticoagulant drug Drugs 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
- G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
L'invention concerne un procédé et un appareil de numération approximative des leucocytes et des plaquettes dans un échantillon sanguin. L'échantillon sanguin, traité par un anticoagulant, est centrifugé dans un tube capillaire, et les distances entre les surfaces de contact entre les différentes couches de cellules sont mesurées dans le tube capillaire éclairé par un faisceau lumineux et mis en rotation de manière à effacer visuellement les irrégularités des surfaces de contact. Applications au diagnostic médical.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/788,509 US4156570A (en) | 1977-04-18 | 1977-04-18 | Apparatus and method for measuring white blood cell and platelet concentrations in blood |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2388277A1 true FR2388277A1 (fr) | 1978-11-17 |
FR2388277B1 FR2388277B1 (fr) | 1982-04-16 |
Family
ID=25144711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7811372A Granted FR2388277A1 (fr) | 1977-04-18 | 1978-04-18 | Procede et appareil de numeration des leucocytes et des plaquettes dans le sang |
Country Status (7)
Country | Link |
---|---|
US (1) | US4156570A (fr) |
JP (1) | JPS53129485A (fr) |
DE (1) | DE2816870C2 (fr) |
FR (1) | FR2388277A1 (fr) |
GB (1) | GB1565492A (fr) |
IT (1) | IT1102583B (fr) |
SU (1) | SU940656A3 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0200303A1 (fr) * | 1985-03-29 | 1986-11-05 | Robert Aaron Levine | Mesure d'une petite couche de composant le plus dense dans un mélange startifié |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4390283A (en) * | 1979-09-04 | 1983-06-28 | Beckman Instruments, Inc. | Magnetic strirrer for sample container |
US4558947A (en) * | 1983-11-07 | 1985-12-17 | Wardlaw Stephen C | Method and apparatus for measuring blood constituent counts |
JPH06100596B2 (ja) * | 1986-09-10 | 1994-12-12 | 東亜医用電子株式会社 | フロ−サイトメトリ−による白血球の分類方法 |
US5030341A (en) * | 1987-04-03 | 1991-07-09 | Andronic Technologies, Inc. | Apparatus for separating phases of blood |
US4828716A (en) * | 1987-04-03 | 1989-05-09 | Andronic Devices, Ltd. | Apparatus and method for separating phases of blood |
US4779976A (en) * | 1987-08-31 | 1988-10-25 | Levine Robert A | Multiparameter hematology measurement for veterinarians |
US5298224A (en) * | 1988-01-14 | 1994-03-29 | Novo Nordisk A/S | Apparatus for determination of the coagulation time of a blood sample |
US4843869A (en) * | 1988-03-21 | 1989-07-04 | Levine Robert A | Method for measuring hemoglobin |
JP2501460B2 (ja) * | 1988-03-23 | 1996-05-29 | オリンパス光学工業株式会社 | ヘマトクリット値の測定方法 |
US4887458A (en) * | 1988-09-21 | 1989-12-19 | Separation Techology, Inc. | Hematocrit reader apparatus and method |
US5239360A (en) * | 1988-10-21 | 1993-08-24 | Applied Biosystems, Inc. | Lens for capillary electrophoresis and chromatography |
US5089384A (en) * | 1988-11-04 | 1992-02-18 | Amoco Corporation | Method and apparatus for selective cell destruction using amplified immunofluorescence |
US5132087A (en) * | 1989-10-16 | 1992-07-21 | Kristen L Manion | Apparatus for measuring blood constituent counts |
US5506145A (en) * | 1994-12-02 | 1996-04-09 | Bull; Brian S. | Determination of an individual's inflammation index from whole blood fibrinogen and hematocrit or hemoglobin measurements |
GB9606559D0 (en) * | 1996-03-28 | 1996-06-05 | Zynocyte Ltd | Apparatus and method for analysing blood samples |
US6152868A (en) * | 1998-03-02 | 2000-11-28 | Becton, Dickinson And Company | Inertial tube indexer |
CA2230222A1 (fr) * | 1997-03-10 | 1998-09-10 | Stephen C. Wardlaw | Methode et assemblage pour la mesure rapide de couches de cellules |
US5888184A (en) * | 1997-03-10 | 1999-03-30 | Robert A. Levine | Method for rapid measurement of cell layers |
US5811303A (en) * | 1997-04-01 | 1998-09-22 | Streck Laboratories, Inc. | Quantitative buffy coat control composition |
US6197523B1 (en) * | 1997-11-24 | 2001-03-06 | Robert A. Levine | Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood |
US6911315B2 (en) * | 1997-11-24 | 2005-06-28 | David L. Rimm | Method for the detection, identification, enumeration and confirmation of virally infected cells and other epitopically defined cells in whole blood |
US6002474A (en) * | 1998-03-02 | 1999-12-14 | Becton Dickinson And Company | Method for using blood centrifugation device with movable optical reader |
US6120429A (en) * | 1998-03-02 | 2000-09-19 | Becton, Dickinson And Company | Method of using inertial tube indexer |
US6285450B1 (en) | 1998-03-02 | 2001-09-04 | Bradley S. Thomas | Blood centrifugation device with movable optical reader |
US6030086A (en) | 1998-03-02 | 2000-02-29 | Becton, Dickinson And Company | Flash tube reflector with arc guide |
US6074883A (en) * | 1998-03-02 | 2000-06-13 | Becton, Dickinson And Company | Method for using disposable blood tube holder |
US6080366A (en) * | 1998-03-02 | 2000-06-27 | Becton, Dickinson And Company | Disposable blood tube holder |
US6153148A (en) * | 1998-06-15 | 2000-11-28 | Becton, Dickinson And Company | Centrifugal hematology disposable |
JP5058815B2 (ja) * | 2004-11-24 | 2012-10-24 | バッテル メモリアル インスティチュート | 細胞撮像用の光学システム |
SE528697C2 (sv) * | 2005-03-11 | 2007-01-30 | Hemocue Ab | Volymetrisk bestämning av antalet vita blodkroppar i ett blodprov |
EP2584360A1 (fr) | 2007-12-05 | 2013-04-24 | Zyomyx Inc. | Kit dýanalyse cellulaire et procédé |
US8988881B2 (en) | 2007-12-18 | 2015-03-24 | Sandia Corporation | Heat exchanger device and method for heat removal or transfer |
EP3685748A1 (fr) * | 2008-03-05 | 2020-07-29 | Becton, Dickinson and Company | Ensemble récipient de collecte à action capillaire |
US9005417B1 (en) | 2008-10-01 | 2015-04-14 | Sandia Corporation | Devices, systems, and methods for microscale isoelectric fractionation |
US20110178424A1 (en) | 2010-01-19 | 2011-07-21 | Becton, Dickinson And Company | Specimen Collection Container Having a Transitional Fill-Volume Indicator Indicating Extraction Method |
US9186668B1 (en) | 2010-06-04 | 2015-11-17 | Sandia Corporation | Microfluidic devices, systems, and methods for quantifying particles using centrifugal force |
US9795961B1 (en) | 2010-07-08 | 2017-10-24 | National Technology & Engineering Solutions Of Sandia, Llc | Devices, systems, and methods for detecting nucleic acids using sedimentation |
US8945914B1 (en) | 2010-07-08 | 2015-02-03 | Sandia Corporation | Devices, systems, and methods for conducting sandwich assays using sedimentation |
US8962346B2 (en) | 2010-07-08 | 2015-02-24 | Sandia Corporation | Devices, systems, and methods for conducting assays with improved sensitivity using sedimentation |
US9261100B2 (en) | 2010-08-13 | 2016-02-16 | Sandia Corporation | Axial flow heat exchanger devices and methods for heat transfer using axial flow devices |
US8460620B2 (en) | 2010-12-03 | 2013-06-11 | Becton, Dickinson And Company | Specimen collection container assembly |
US9244065B1 (en) | 2012-03-16 | 2016-01-26 | Sandia Corporation | Systems, devices, and methods for agglutination assays using sedimentation |
US9903001B1 (en) | 2012-07-19 | 2018-02-27 | National Technology & Engineering Solutions Of Sandia, Llc | Quantitative detection of pathogens in centrifugal microfluidic disks |
US10197480B2 (en) | 2012-11-07 | 2019-02-05 | Sandstone Diagnostics, Inc. | Methods and devices for processing samples and counting cells |
EP2917362A4 (fr) | 2012-11-07 | 2016-07-13 | Sandstone Diagnostics Inc | Procédés et dispositifs de traitement d'échantillons et de numération de cellules |
US9304128B1 (en) | 2013-02-01 | 2016-04-05 | Sandia Corporation | Toxin activity assays, devices, methods and systems therefor |
WO2014124179A1 (fr) | 2013-02-07 | 2014-08-14 | Sandstone Diagnostics, Inc. | Traitement d'échantillons, répartition de fluides et dosage à sédimentation automatisés |
US9500579B1 (en) | 2013-05-01 | 2016-11-22 | Sandia Corporation | System and method for detecting components of a mixture including tooth elements for alignment |
CN103558403A (zh) * | 2013-10-23 | 2014-02-05 | 北京倍肯恒业科技发展有限责任公司 | 一种干式血液细胞分析装置的主控数据处理*** |
CN103528936B (zh) * | 2013-10-23 | 2016-05-18 | 北京倍肯恒业科技发展股份有限公司 | 一种干式血液细胞分析装置的光学检测*** |
CN103529231B (zh) * | 2013-10-23 | 2016-01-13 | 北京倍肯恒业科技发展有限责任公司 | 一种干式血液细胞分析装置的机械进样*** |
CN103529230B (zh) * | 2013-10-23 | 2015-07-29 | 北京倍肯恒业科技发展有限责任公司 | 一种干式血液细胞分析装置 |
US9803238B1 (en) | 2013-11-26 | 2017-10-31 | National Technology & Engineering Solutions Of Sandia, Llc | Method and apparatus for purifying nucleic acids and performing polymerase chain reaction assays using an immiscible fluid |
US9702871B1 (en) | 2014-11-18 | 2017-07-11 | National Technology & Engineering Solutions Of Sandia, Llc | System and method for detecting components of a mixture including a valving scheme for competition assays |
US10254298B1 (en) | 2015-03-25 | 2019-04-09 | National Technology & Engineering Solutions Of Sandia, Llc | Detection of metabolites for controlled substances |
KR101701334B1 (ko) * | 2015-11-24 | 2017-02-13 | 전북대학교산학협력단 | 포터블 혈액점도측정장치 |
US10406528B1 (en) | 2016-08-04 | 2019-09-10 | National Technology & Engineering Solutions Of Sandia, Llc | Non-contact temperature control system for microfluidic devices |
US10981174B1 (en) | 2016-08-04 | 2021-04-20 | National Technology & Engineering Solutions Of Sandia, Llc | Protein and nucleic acid detection for microfluidic devices |
US10786811B1 (en) | 2016-10-24 | 2020-09-29 | National Technology & Engineering Solutions Of Sandia, Llc | Detection of active and latent infections with microfluidic devices and systems thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2840915A (en) * | 1954-03-23 | 1958-07-01 | Louis E Drummond | Apparatus for determining the percentage of red cells in a blood specimen |
US3561877A (en) * | 1967-06-30 | 1971-02-09 | Delta Research Inc | Hematocrit reader |
FR2117584A5 (fr) * | 1970-12-09 | 1972-07-21 | Lode Instr Nv |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2973580A (en) * | 1958-09-24 | 1961-03-07 | American Optical Corp | Apparatus for use in analyzing blood |
US3582218A (en) * | 1969-10-17 | 1971-06-01 | Atomic Energy Commission | Multistation photometric analyzer |
US3916205A (en) * | 1973-05-31 | 1975-10-28 | Block Engineering | Differential counting of leukocytes and other cells |
US3914985A (en) * | 1974-03-29 | 1975-10-28 | American Hospital Supply Corp | Centrifuging device and method |
US4031399A (en) * | 1975-02-24 | 1977-06-21 | Beckman Instruments, Inc. | Fluorometer |
US4054387A (en) * | 1975-12-22 | 1977-10-18 | Vickers Instruments, Inc. | Measuring with microscope |
US4027660A (en) * | 1976-04-02 | 1977-06-07 | Wardlaw Stephen C | Material layer volume determination |
-
1977
- 1977-04-18 US US05/788,509 patent/US4156570A/en not_active Expired - Lifetime
-
1978
- 1978-03-23 GB GB11753/78A patent/GB1565492A/en not_active Expired
- 1978-04-12 IT IT48875/78A patent/IT1102583B/it active
- 1978-04-17 JP JP4515478A patent/JPS53129485A/ja active Granted
- 1978-04-17 SU SU782605501A patent/SU940656A3/ru active
- 1978-04-18 DE DE2816870A patent/DE2816870C2/de not_active Expired
- 1978-04-18 FR FR7811372A patent/FR2388277A1/fr active Granted
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2840915A (en) * | 1954-03-23 | 1958-07-01 | Louis E Drummond | Apparatus for determining the percentage of red cells in a blood specimen |
US3561877A (en) * | 1967-06-30 | 1971-02-09 | Delta Research Inc | Hematocrit reader |
FR2117584A5 (fr) * | 1970-12-09 | 1972-07-21 | Lode Instr Nv |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0200303A1 (fr) * | 1985-03-29 | 1986-11-05 | Robert Aaron Levine | Mesure d'une petite couche de composant le plus dense dans un mélange startifié |
Also Published As
Publication number | Publication date |
---|---|
DE2816870C2 (de) | 1987-04-23 |
US4156570A (en) | 1979-05-29 |
DE2816870A1 (de) | 1978-10-26 |
FR2388277B1 (fr) | 1982-04-16 |
SU940656A3 (ru) | 1982-06-30 |
IT7848875A0 (it) | 1978-04-12 |
GB1565492A (en) | 1980-04-23 |
JPS6139620B2 (fr) | 1986-09-04 |
IT1102583B (it) | 1985-10-07 |
JPS53129485A (en) | 1978-11-11 |
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