FR2387975A1 - Nouveaux analogues de prostacycline et leur preparation - Google Patents
Nouveaux analogues de prostacycline et leur preparationInfo
- Publication number
- FR2387975A1 FR2387975A1 FR7732557A FR7732557A FR2387975A1 FR 2387975 A1 FR2387975 A1 FR 2387975A1 FR 7732557 A FR7732557 A FR 7732557A FR 7732557 A FR7732557 A FR 7732557A FR 2387975 A1 FR2387975 A1 FR 2387975A1
- Authority
- FR
- France
- Prior art keywords
- preparation
- new
- prostacycline
- analogues
- analogs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical class O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000003815 prostacyclins Chemical class 0.000 abstract 1
- -1 prostaglandin compounds Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Abstract
L'invention est relative à de nouveaux analogues de dihydroprostacycline. Ces analogues sont des éthers 9-désoxy-5,9-cycliques de composés de prostaglandines du type F1 alpha , à un noyau hexagonal, la liaison entre la chaîne laterale et le noyau hétérocyclique étant une liaison saturée. Utilisations pharmaceutiques semblables à celles des dérivés connus de prostacycline.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78814477A | 1977-04-19 | 1977-04-19 | |
US78814377A | 1977-04-19 | 1977-04-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2387975A1 true FR2387975A1 (fr) | 1978-11-17 |
FR2387975B1 FR2387975B1 (fr) | 1980-08-08 |
Family
ID=27120750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7732557A Granted FR2387975A1 (fr) | 1977-04-19 | 1977-10-28 | Nouveaux analogues de prostacycline et leur preparation |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS53132573A (fr) |
AU (1) | AU509357B2 (fr) |
CA (1) | CA1184906A (fr) |
CH (1) | CH636347A5 (fr) |
DE (1) | DE2746932A1 (fr) |
FR (1) | FR2387975A1 (fr) |
GB (1) | GB1554050A (fr) |
NL (1) | NL7800011A (fr) |
SE (1) | SE434266B (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2409997A1 (fr) * | 1977-11-23 | 1979-06-22 | Miles Lab | |
CZ303625B6 (cs) * | 1999-10-15 | 2013-01-16 | Sucampo Ag | Stabilní farmaceutický prostredek obsahující bicyklickou slouceninu a acyglycerol, bicyklická sloucenina, zpusob stabilizace bicyklické slouceniny, farmaceutický prostredek obsahující bicyklickou slouceninu |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02294718A (ja) * | 1989-05-09 | 1990-12-05 | Fujitsu Ltd | ディジタル信号入力回路 |
PL2653468T3 (pl) | 2009-07-28 | 2016-08-31 | Ono Pharmaceutical Co | Bicykliczny związek i jego zastosowania do celów medycznych |
EP2669280B1 (fr) | 2011-01-27 | 2016-04-27 | ONO Pharmaceutical Co., Ltd. | Composé bicyclique et son utilisation à des fins médicales |
EP2669279B1 (fr) | 2011-01-27 | 2017-01-11 | ONO Pharmaceutical Co., Ltd. | Composé bicyclique et utilisation associée à des fins médicales |
ES2890989T3 (es) | 2016-06-30 | 2022-01-25 | Ono Pharmaceutical Co | Método para producir un compuesto bicíclico |
-
1977
- 1977-08-22 CA CA000285239A patent/CA1184906A/fr not_active Expired
- 1977-08-23 SE SE7709477A patent/SE434266B/xx not_active IP Right Cessation
- 1977-08-25 AU AU28206/77A patent/AU509357B2/en not_active Expired
- 1977-09-01 GB GB36450/77A patent/GB1554050A/en not_active Expired
- 1977-10-04 JP JP11872477A patent/JPS53132573A/ja active Granted
- 1977-10-19 DE DE19772746932 patent/DE2746932A1/de active Granted
- 1977-10-24 CH CH1293077A patent/CH636347A5/de not_active IP Right Cessation
- 1977-10-28 FR FR7732557A patent/FR2387975A1/fr active Granted
-
1978
- 1978-01-02 NL NL7800011A patent/NL7800011A/xx not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2409997A1 (fr) * | 1977-11-23 | 1979-06-22 | Miles Lab | |
CZ303625B6 (cs) * | 1999-10-15 | 2013-01-16 | Sucampo Ag | Stabilní farmaceutický prostredek obsahující bicyklickou slouceninu a acyglycerol, bicyklická sloucenina, zpusob stabilizace bicyklické slouceniny, farmaceutický prostredek obsahující bicyklickou slouceninu |
Also Published As
Publication number | Publication date |
---|---|
JPS53132573A (en) | 1978-11-18 |
CA1184906A (fr) | 1985-04-02 |
CH636347A5 (en) | 1983-05-31 |
AU2820677A (en) | 1979-03-01 |
NL7800011A (nl) | 1978-10-23 |
DE2746932C2 (fr) | 1988-03-31 |
JPS6151597B2 (fr) | 1986-11-10 |
SE434266B (sv) | 1984-07-16 |
DE2746932A1 (de) | 1978-11-02 |
AU509357B2 (en) | 1980-05-08 |
FR2387975B1 (fr) | 1980-08-08 |
GB1554050A (en) | 1979-10-17 |
SE7709477L (sv) | 1978-10-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |