FR2374904A1 - 1-Methyl 2-(phenyl oxymethyl) 5-nitro imidazoles - for control of protozoa, helminths and ectoparasites - Google Patents

1-Methyl 2-(phenyl oxymethyl) 5-nitro imidazoles - for control of protozoa, helminths and ectoparasites

Info

Publication number
FR2374904A1
FR2374904A1 FR7633961A FR7633961A FR2374904A1 FR 2374904 A1 FR2374904 A1 FR 2374904A1 FR 7633961 A FR7633961 A FR 7633961A FR 7633961 A FR7633961 A FR 7633961A FR 2374904 A1 FR2374904 A1 FR 2374904A1
Authority
FR
France
Prior art keywords
methyl
ectoparasites
helminths
protozoa
control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7633961A
Other languages
French (fr)
Other versions
FR2374904B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to FR7633961A priority Critical patent/FR2374904A1/en
Publication of FR2374904A1 publication Critical patent/FR2374904A1/en
Application granted granted Critical
Publication of FR2374904B1 publication Critical patent/FR2374904B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

New 1-methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles of formula (I) and their salts with physiologically compatible acids. (where R1-3 are H or 1-4C alkyl, or R1-C-N-R2 forms a pyrrolidine piperidine or hexamethyleneimine ring; or -NR2R3 forms a pyrrolidine, piperidine, morpholine or thiomorpholine ring), can be used to treat protozoon infestations in man and animals caused, e.g., by Trichomonas vaginalis and Entamoeba histolytica. They are also anthelmintics and act against ectoparasites e.g. ticks. (I) can be given orally or topically in conventional pharmaceutical prepns. A suitable oral dose is 10-750 mg.
FR7633961A 1976-11-10 1976-11-10 1-Methyl 2-(phenyl oxymethyl) 5-nitro imidazoles - for control of protozoa, helminths and ectoparasites Granted FR2374904A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7633961A FR2374904A1 (en) 1976-11-10 1976-11-10 1-Methyl 2-(phenyl oxymethyl) 5-nitro imidazoles - for control of protozoa, helminths and ectoparasites

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7633961A FR2374904A1 (en) 1976-11-10 1976-11-10 1-Methyl 2-(phenyl oxymethyl) 5-nitro imidazoles - for control of protozoa, helminths and ectoparasites

Publications (2)

Publication Number Publication Date
FR2374904A1 true FR2374904A1 (en) 1978-07-21
FR2374904B1 FR2374904B1 (en) 1980-08-01

Family

ID=9179767

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7633961A Granted FR2374904A1 (en) 1976-11-10 1976-11-10 1-Methyl 2-(phenyl oxymethyl) 5-nitro imidazoles - for control of protozoa, helminths and ectoparasites

Country Status (1)

Country Link
FR (1) FR2374904A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2294700A1 (en) * 1974-12-16 1976-07-16 Hoechst Ag 1-ALKYL-2- (PHENOXYMETHYL) -5-NITRO-IMIDAZOLES, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2294700A1 (en) * 1974-12-16 1976-07-16 Hoechst Ag 1-ALKYL-2- (PHENOXYMETHYL) -5-NITRO-IMIDAZOLES, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS

Also Published As

Publication number Publication date
FR2374904B1 (en) 1980-08-01

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Legal Events

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