FR2370733A1 - Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments - Google Patents

Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments

Info

Publication number
FR2370733A1
FR2370733A1 FR7735116A FR7735116A FR2370733A1 FR 2370733 A1 FR2370733 A1 FR 2370733A1 FR 7735116 A FR7735116 A FR 7735116A FR 7735116 A FR7735116 A FR 7735116A FR 2370733 A1 FR2370733 A1 FR 2370733A1
Authority
FR
France
Prior art keywords
piperidine
derivatives
polysubstitute
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7735116A
Other languages
English (en)
Other versions
FR2370733B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anphar SA
Original Assignee
Anphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anphar SA filed Critical Anphar SA
Publication of FR2370733A1 publication Critical patent/FR2370733A1/fr
Application granted granted Critical
Publication of FR2370733B1 publication Critical patent/FR2370733B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Ces dérivés polysubstitués de la pipéridine ont pour formule générale :
FR7735116A 1976-11-16 1977-11-16 Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments Granted FR2370733A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47739/76A GB1574418A (en) 1976-11-16 1976-11-16 Piperidine derivatives

Publications (2)

Publication Number Publication Date
FR2370733A1 true FR2370733A1 (fr) 1978-06-09
FR2370733B1 FR2370733B1 (fr) 1980-07-04

Family

ID=10446086

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7735116A Granted FR2370733A1 (fr) 1976-11-16 1977-11-16 Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments
FR7735115A Granted FR2370732A1 (fr) 1976-11-16 1977-11-16 Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7735115A Granted FR2370732A1 (fr) 1976-11-16 1977-11-16 Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments

Country Status (13)

Country Link
US (1) US5026858A (fr)
JP (2) JPS5387365A (fr)
AT (2) AT360013B (fr)
AU (2) AU517004B2 (fr)
BE (2) BE860736A (fr)
CA (2) CA1095046A (fr)
DE (2) DE2751138A1 (fr)
ES (4) ES464144A1 (fr)
FR (2) FR2370733A1 (fr)
GB (1) GB1574418A (fr)
IE (2) IE45989B1 (fr)
NL (2) NL7712559A (fr)
ZA (2) ZA776588B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2546169A1 (fr) * 1983-05-20 1984-11-23 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1574418A (en) * 1976-11-16 1980-09-03 Anphar Sa Piperidine derivatives
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
US4820715A (en) * 1984-06-28 1989-04-11 Bristol-Myers Company Anti-emetic quinuclidinyl benzamides
US5011992A (en) * 1984-06-28 1991-04-30 Bristol-Myers Squibb Company Pharmacologically active substituted benzamides
GB8519707D0 (en) * 1985-08-06 1985-09-11 Fordonal Sa Chemical compounds
EP1114823A3 (fr) * 1992-08-19 2001-07-18 Pfizer Inc. Benzylamino azote substitue renfermant des heterocycles non aromatiques
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5827875A (en) * 1996-05-10 1998-10-27 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5885983A (en) * 1996-05-10 1999-03-23 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5883109A (en) * 1996-07-24 1999-03-16 Bristol-Myers Squibb Company Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
IL125658A0 (en) 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
US6339087B1 (en) 1997-08-18 2002-01-15 Syntex (U.S.A.) Llc Cyclic amine derivatives-CCR-3 receptor antagonists
TR200101397T2 (tr) * 1998-11-20 2001-11-21 F.Hoffmann-La Roche Ag Piperidin CCR-3 reseptörü antagonistleri
FR2802206B1 (fr) 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
TW200800953A (en) * 2002-10-30 2008-01-01 Theravance Inc Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine
WO2005007645A1 (fr) * 2003-07-11 2005-01-27 Theravance, Inc. Composes de 4-amino-1-benzylpiperidine substitues
WO2005053663A2 (fr) * 2003-11-24 2005-06-16 Eli Lilly And Company Traitement de la defaillance cognitive
CN101189226A (zh) * 2005-06-02 2008-05-28 霍夫曼-拉罗奇有限公司 哌啶-4-基-酰胺衍生物及它们作为sst受体亚型5拮抗剂的应用
JP2009264436A (ja) 2008-04-23 2009-11-12 Funai Electric Co Ltd トルクリミッタ装置、トルクリミッタ装置を備えた表示画面旋回装置およびトルクリミッタ装置を含むテレビジョン装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1019781A (fr) * 1963-03-05
FR1407055A (fr) * 1963-03-05 1965-07-30 Ile De France Nouveau procédé de préparation de benzamides substitués
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR5916M (fr) * 1966-01-21 1968-05-06
US3577440A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-amido-pyrrolidines
GB1345872A (en) * 1970-09-03 1974-02-06 Wyeth John & Brother Ltd Amino-and acylamino-pyridine and hydropyridine derivatives
US3963745A (en) * 1972-04-03 1976-06-15 A. H. Robins Company, Incorporated Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
DE2513136C3 (de) * 1974-03-21 1981-04-30 Anphar S.A., Madrid N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
GB1513631A (en) * 1976-02-17 1978-06-07 Gallardo Antonio Sa Piperidine derivatives
US4163789A (en) * 1976-02-17 1979-08-07 Anphar, S.A. Anti-psychotic (cycloalkenylalkylpiperidino) benzamides
GB1574418A (en) * 1976-11-16 1980-09-03 Anphar Sa Piperidine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2546169A1 (fr) * 1983-05-20 1984-11-23 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
BE860737A (fr) 1978-03-01
AU3067277A (en) 1979-05-24
ATA817177A (de) 1980-05-15
AT360014B (de) 1980-12-10
ATA817077A (de) 1980-05-15
ES464144A1 (es) 1978-09-01
IE46090B1 (en) 1983-02-23
ZA776587B (en) 1978-09-27
ES464146A1 (es) 1978-09-01
AU517004B2 (en) 1981-07-02
JPS6127388B2 (fr) 1986-06-25
ES464145A1 (es) 1978-09-01
CA1095046A (fr) 1981-02-03
NL7712570A (nl) 1978-05-18
FR2370732B1 (fr) 1980-07-04
BE860736A (fr) 1978-03-01
ZA776588B (en) 1978-08-30
NL7712559A (nl) 1978-05-18
AT360013B (de) 1980-12-10
FR2370733B1 (fr) 1980-07-04
US5026858A (en) 1991-06-25
IE46090L (en) 1978-05-16
DE2751138A1 (de) 1978-05-24
JPS5390267A (en) 1978-08-08
AU517830B2 (en) 1981-08-27
AU3067377A (en) 1979-05-24
JPS6126782B2 (fr) 1986-06-21
GB1574418A (en) 1980-09-03
IE45989L (en) 1978-05-16
JPS5387365A (en) 1978-08-01
ES464147A1 (es) 1978-09-01
IE45989B1 (en) 1983-01-26
CA1094072A (fr) 1981-01-20
FR2370732A1 (fr) 1978-06-09
DE2751139A1 (de) 1978-05-24

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Legal Events

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CD Change of name or company name
TP Transmission of property