FR2368952A1 - Nouveaux aminoalcoxy-4 (2 h) pyranone-2,3 substitues-5,6 condenses - Google Patents

Nouveaux aminoalcoxy-4 (2 h) pyranone-2,3 substitues-5,6 condenses

Info

Publication number
FR2368952A1
FR2368952A1 FR7605234A FR7605234A FR2368952A1 FR 2368952 A1 FR2368952 A1 FR 2368952A1 FR 7605234 A FR7605234 A FR 7605234A FR 7605234 A FR7605234 A FR 7605234A FR 2368952 A1 FR2368952 A1 FR 2368952A1
Authority
FR
France
Prior art keywords
pyranone
aminoalcoxy
condenses
substitutes
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7605234A
Other languages
English (en)
Other versions
FR2368952B1 (fr
Inventor
Philippe Briet
Jean-Jacques Berthelon
Jean-Claude Depin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sante SAS
Original Assignee
LIPHA SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LIPHA SAS filed Critical LIPHA SAS
Priority to FR7605234A priority Critical patent/FR2368952A1/fr
Priority to BE174194A priority patent/BE850522A/fr
Priority to CH84077A priority patent/CH620918A5/fr
Priority to CS77854A priority patent/CS195325B2/cs
Priority to ZA770741A priority patent/ZA77741B/xx
Priority to IL51428A priority patent/IL51428A/xx
Priority to IE319/77A priority patent/IE44489B1/en
Priority to CA272,042A priority patent/CA1092112A/fr
Priority to IT2030977A priority patent/IT1077635B/it
Priority to YU00449/77A priority patent/YU44977A/xx
Priority to GB7056/77A priority patent/GB1566491A/en
Priority to SU772455454A priority patent/SU638259A3/ru
Priority to DE19772707746 priority patent/DE2707746A1/de
Priority to AU22556/77A priority patent/AU510619B2/en
Priority to ES456243A priority patent/ES456243A1/es
Priority to MX775464U priority patent/MX4161E/es
Priority to AT126277A priority patent/AT352720B/de
Priority to NO770619A priority patent/NO145841C/no
Priority to DK80777A priority patent/DK80777A/da
Priority to HU77LI308A priority patent/HU178275B/hu
Priority to SE7702041A priority patent/SE7702041L/xx
Priority to AR266683A priority patent/AR218444A1/es
Priority to JP1937077A priority patent/JPS52122371A/ja
Priority to NL7702090A priority patent/NL7702090A/xx
Publication of FR2368952A1 publication Critical patent/FR2368952A1/fr
Priority to AT775978A priority patent/AT357157B/de
Priority to US06/018,875 priority patent/US4230850A/en
Application granted granted Critical
Publication of FR2368952B1 publication Critical patent/FR2368952B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/56Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

La présente invention concerne des aminoalcoxy-4 Ø2 Hõ pyranone-substitués-5,6 condensés. Ces composés sont représentés par la formule :
FR7605234A 1976-02-25 1976-02-25 Nouveaux aminoalcoxy-4 (2 h) pyranone-2,3 substitues-5,6 condenses Granted FR2368952A1 (fr)

Priority Applications (26)

Application Number Priority Date Filing Date Title
FR7605234A FR2368952A1 (fr) 1976-02-25 1976-02-25 Nouveaux aminoalcoxy-4 (2 h) pyranone-2,3 substitues-5,6 condenses
BE174194A BE850522A (fr) 1976-02-25 1977-01-19 Nouveaux aminoalcoxy-4(2h)pyranone-2,3 substitues-5,6 condenses
CH84077A CH620918A5 (fr) 1976-02-25 1977-01-24
ZA770741A ZA77741B (en) 1976-02-25 1977-02-09 New 3-substituted-4-aminoalcoxy-5.6-condensed ring-(2h)-pyran-2-ones
CS77854A CS195325B2 (en) 1976-02-25 1977-02-09 Method of producing 4-aminoalkoxy-2/2h/pyranones 3-substituted and 5,6-condensed
IL51428A IL51428A (en) 1976-02-25 1977-02-11 3-substituted-4-aminoalkoxy-5,6-condensed ring-(2h)-pyran-2-ones,their preparation and pharmaceutical compositions containing them
IE319/77A IE44489B1 (en) 1976-02-25 1977-02-14 Substituted pyranones and process for preparing them
CA272,042A CA1092112A (fr) 1976-02-25 1977-02-15 Obtention de 4-aminoalcoxy-5,6-noyaux condenses-2- pyranones substituees en 3
IT2030977A IT1077635B (it) 1976-02-25 1977-02-15 Amminoalcossi-4 (2h)piranone-2,3 sostituiti-5,6 condensati
YU00449/77A YU44977A (en) 1976-02-25 1977-02-18 Process for obtaining 2,3-substituted 5,6-condensed aminoalkoxy-4(2h)-pyranones
GB7056/77A GB1566491A (en) 1976-02-25 1977-02-18 Substituted pyranones and their preparation
SU772455454A SU638259A3 (ru) 1976-02-25 1977-02-21 Способ получени 2,3-замещенных 5,6-конденсированных 4-(2н)-аминоалкоксипиранонов или их солей
DE19772707746 DE2707746A1 (de) 1976-02-25 1977-02-23 5,6-substituierte, kondensierte 4-(2h)-aminoalkoxy-2,3-pyranone, verfahren zu deren herstellung und sie enthaltende arzneimittel
AU22556/77A AU510619B2 (en) 1976-02-25 1977-02-23 3-substituted-4-aminoalcoxy-5, 6-condensed ring-(2h)-pyran-2-ones
SE7702041A SE7702041L (sv) 1976-02-25 1977-02-24 Forfarande for framstellning av 2,3-substituerade, 5,6-kondenserade 4(2h)-aminoalkoxi-pyranoner med hypotensiv, anti-ischemi-och antihostverkan
AT126277A AT352720B (de) 1976-02-25 1977-02-24 Verfahren zur herstellung neuer 5,6-substi- tuierter, kondensierter 4- (2h)-aminoalkoxy- 2,3-pyranone und deren salze und optischer isomere
NO770619A NO145841C (no) 1976-02-25 1977-02-24 Analogifremgangsmaate for fremstilling av terapeutisk aktive 2,3-substituerte, 5,6-kondenserte 4(2h)-aminoalkoksy-pyranoner med hypotensiv, anti-ischaemia- og anti-hostevirkning
DK80777A DK80777A (da) 1976-02-25 1977-02-24 Fremgangsmade til fremstilling af 2,3-substituerede, 5,6-kondenserede 4(2h)-aminoalkoxypyranoner
HU77LI308A HU178275B (en) 1976-02-25 1977-02-24 Process for producing codensed derivatives of 4-amino-alkoxy-bracket-2h-bracket closed-piran-2-one
MX775464U MX4161E (es) 1976-02-25 1977-02-24 Procedimiento de preparacion de compuestos de amino-alcoxi-4(2h)-piranona-2,3 substituidos condensados-5,62
ES456243A ES456243A1 (es) 1976-02-25 1977-02-24 Un procedimiento de preparacion de compuestos de aminoalcoxi4-(2h)-piranona-2, sustituidos en posicion 3 y condensados en posicion 5,6.
AR266683A AR218444A1 (es) 1976-02-25 1977-02-25 Procedimiento para preparar nuevos compuestos derivados de la aminoalcoxi-4 alquil,fenil o bencil-(2h)piran-2-ona condensados en posicion 5,6
JP1937077A JPS52122371A (en) 1976-02-25 1977-02-25 *2h* pyrann22one derivative and method for their production and pharmaceutical composition containing same
NL7702090A NL7702090A (nl) 1976-02-25 1977-02-25 Werkwijze voor de bereiding van gecondenseerde 5,6-gesubstitueerde 4-aminoalkoxy (2) 2,3-pyranon- verbindingen en hun additiezouten en tussenpro- dukten alsmede gevormd farmaceutisch preparaat.
AT775978A AT357157B (de) 1976-02-25 1978-10-30 Verfahren zur herstellung neuer 5,6-substi- tuierter kondensierter 4-(2h)-aminoalkoxy-2,3- pyranone und deren salze und optischen isomeren
US06/018,875 US4230850A (en) 1976-02-25 1979-03-09 3-Substituted-4-aminoalkoxy-5,6-condensed ring-2-pyranones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7605234A FR2368952A1 (fr) 1976-02-25 1976-02-25 Nouveaux aminoalcoxy-4 (2 h) pyranone-2,3 substitues-5,6 condenses

Publications (2)

Publication Number Publication Date
FR2368952A1 true FR2368952A1 (fr) 1978-05-26
FR2368952B1 FR2368952B1 (fr) 1980-04-30

Family

ID=9169581

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7605234A Granted FR2368952A1 (fr) 1976-02-25 1976-02-25 Nouveaux aminoalcoxy-4 (2 h) pyranone-2,3 substitues-5,6 condenses

Country Status (24)

Country Link
US (1) US4230850A (fr)
JP (1) JPS52122371A (fr)
AR (1) AR218444A1 (fr)
AT (1) AT352720B (fr)
AU (1) AU510619B2 (fr)
BE (1) BE850522A (fr)
CA (1) CA1092112A (fr)
CH (1) CH620918A5 (fr)
CS (1) CS195325B2 (fr)
DE (1) DE2707746A1 (fr)
DK (1) DK80777A (fr)
ES (1) ES456243A1 (fr)
FR (1) FR2368952A1 (fr)
GB (1) GB1566491A (fr)
HU (1) HU178275B (fr)
IE (1) IE44489B1 (fr)
IL (1) IL51428A (fr)
MX (1) MX4161E (fr)
NL (1) NL7702090A (fr)
NO (1) NO145841C (fr)
SE (1) SE7702041L (fr)
SU (1) SU638259A3 (fr)
YU (1) YU44977A (fr)
ZA (1) ZA77741B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2368952A1 (fr) 1976-02-25 1978-05-26 Lipha Nouveaux aminoalcoxy-4 (2 h) pyranone-2,3 substitues-5,6 condenses
US4259327A (en) 1979-04-02 1981-03-31 Merck & Co., Inc. Substituted aminoalkoxypyridines, compositions and use thereof
DE3209271A1 (de) * 1982-03-13 1983-09-15 Boehringer Mannheim Gmbh, 6800 Mannheim Bicyclische phenolether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
ES2157462T3 (es) * 1995-10-13 2001-08-16 Aventis Cropscience Uk Ltd Fungicidas heterociclicos.
DE10030094A1 (de) * 2000-06-19 2001-12-20 Bayer Ag Phenylsubstituierte 5,6-Dihydro-pyron-Derivate
US7538233B2 (en) * 2003-09-05 2009-05-26 Aventis Pharmaceuticals Inc. Coumarins as iNOS inhibitors
EP3133066A1 (fr) * 2015-08-21 2017-02-22 Merck Patent GmbH Composés hydrophiles pour dispositifs optiquement actifs
EP3133065A1 (fr) 2015-08-21 2017-02-22 Merck Patent GmbH Composés de dispositifs optiquement actifs
EP3363793A1 (fr) 2017-02-15 2018-08-22 Merck Patent GmbH Composés hydrophobes pour dispositifs optiquement actifs
EP3363786A1 (fr) 2017-02-15 2018-08-22 Merck Patent GmbH Composés de dispositifs optiquement actifs
CN111620848A (zh) * 2020-04-29 2020-09-04 华东师范大学 含吡喃和中环骨架的三环稠合芳香体系化合物及其合成和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2368952A1 (fr) 1976-02-25 1978-05-26 Lipha Nouveaux aminoalcoxy-4 (2 h) pyranone-2,3 substitues-5,6 condenses

Also Published As

Publication number Publication date
FR2368952B1 (fr) 1980-04-30
ATA126277A (de) 1979-03-15
ZA77741B (en) 1977-12-28
CS195325B2 (en) 1980-01-31
BE850522A (fr) 1977-07-19
NL7702090A (nl) 1977-08-29
SU638259A3 (ru) 1978-12-15
IE44489B1 (en) 1981-12-16
IE44489L (en) 1977-08-25
DK80777A (da) 1977-08-26
IL51428A (en) 1981-06-29
NO145841C (no) 1982-06-09
NO145841B (no) 1982-03-01
HU178275B (en) 1982-04-28
IL51428A0 (en) 1977-04-29
AT352720B (de) 1979-10-10
CH620918A5 (fr) 1980-12-31
YU44977A (en) 1982-06-30
JPS52122371A (en) 1977-10-14
ES456243A1 (es) 1978-01-16
SE7702041L (sv) 1977-08-26
NO770619L (no) 1977-08-26
MX4161E (es) 1982-01-14
AU510619B2 (en) 1980-07-03
AR218444A1 (es) 1980-06-13
US4230850A (en) 1980-10-28
CA1092112A (fr) 1980-12-23
AU2255677A (en) 1978-08-31
GB1566491A (en) 1980-04-30
DE2707746A1 (de) 1977-09-01

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