FR2362115A1 - Nouveaux aryloxy-1 amino-3 propanols-2, leur preparation et leur utilisation, notamment en therapeutique - Google Patents

Nouveaux aryloxy-1 amino-3 propanols-2, leur preparation et leur utilisation, notamment en therapeutique

Info

Publication number
FR2362115A1
FR2362115A1 FR7724280A FR7724280A FR2362115A1 FR 2362115 A1 FR2362115 A1 FR 2362115A1 FR 7724280 A FR7724280 A FR 7724280A FR 7724280 A FR7724280 A FR 7724280A FR 2362115 A1 FR2362115 A1 FR 2362115A1
Authority
FR
France
Prior art keywords
beta
phenoxy
derivs
hypertension
propanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7724280A
Other languages
English (en)
Inventor
Jean-Claude Cognacq
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexachimie SA
Original Assignee
Hexachimie SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexachimie SA filed Critical Hexachimie SA
Publication of FR2362115A1 publication Critical patent/FR2362115A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Aryloxy-1 amino-3 propanols-2 ayant la formule générale suivante :
FR7724280A 1976-08-21 1977-08-05 Nouveaux aryloxy-1 amino-3 propanols-2, leur preparation et leur utilisation, notamment en therapeutique Withdrawn FR2362115A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB3491276 1976-08-21
GB5343176 1976-12-21
GB5455976 1976-12-22

Publications (1)

Publication Number Publication Date
FR2362115A1 true FR2362115A1 (fr) 1978-03-17

Family

ID=27259250

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7724280A Withdrawn FR2362115A1 (fr) 1976-08-21 1977-08-05 Nouveaux aryloxy-1 amino-3 propanols-2, leur preparation et leur utilisation, notamment en therapeutique

Country Status (11)

Country Link
JP (1) JPS5325528A (fr)
DD (1) DD132431A5 (fr)
DE (1) DE2736106A1 (fr)
DK (1) DK368877A (fr)
ES (1) ES461779A1 (fr)
FR (1) FR2362115A1 (fr)
GR (1) GR59194B (fr)
NL (1) NL7708845A (fr)
NO (1) NO772887L (fr)
PT (1) PT66890B (fr)
SE (1) SE7709142L (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0296265A1 (fr) * 1987-06-23 1988-12-28 Helopharm W. Petrik GmbH & Co.KG. Dérivés aminopropanols de 3-(3-hydroxyphényl)-1-propanone, leur procédé de préparation et médicaments contenant ces composés
EP0296592A2 (fr) * 1987-06-23 1988-12-28 Helopharm W. Petrik GmbH & Co.KG. Dérivés aminopropanols de 3-(2-hydroxyphényl)-1-propanone, leur procédé de préparation et médicaments contenant ces composés
EP0296264A1 (fr) * 1987-06-23 1988-12-28 Helopharm W. Petrik GmbH & Co.KG. Dérivés aminopropanols de 3-(2-hydroxyphényl)-propanone, leur procédé de préparation et médicaments contenant ces composés

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8004088L (sv) * 1980-06-02 1981-12-03 Haessle Ab Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ...
SE8004087L (sv) * 1980-06-02 1981-12-03 Haessle Ab Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ...

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0296265A1 (fr) * 1987-06-23 1988-12-28 Helopharm W. Petrik GmbH & Co.KG. Dérivés aminopropanols de 3-(3-hydroxyphényl)-1-propanone, leur procédé de préparation et médicaments contenant ces composés
EP0296592A2 (fr) * 1987-06-23 1988-12-28 Helopharm W. Petrik GmbH & Co.KG. Dérivés aminopropanols de 3-(2-hydroxyphényl)-1-propanone, leur procédé de préparation et médicaments contenant ces composés
EP0296264A1 (fr) * 1987-06-23 1988-12-28 Helopharm W. Petrik GmbH & Co.KG. Dérivés aminopropanols de 3-(2-hydroxyphényl)-propanone, leur procédé de préparation et médicaments contenant ces composés
EP0297435A2 (fr) * 1987-06-23 1989-01-04 Helopharm W. Petrik GmbH & Co.KG. Dérivés aminopropanols de 3-(3'-hydroxyphényl)-1-propanone, procédé pour leur préparation et mèdicaments contenant ces composés
EP0297435A3 (en) * 1987-06-23 1989-01-11 Helopharm W. Petrik Gmbh & Co.Kg. Aminopropanol derivatives of 3-(3-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds
EP0296592A3 (en) * 1987-06-23 1990-05-09 Helopharm W. Petrik Gmbh & Co.Kg. Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone, process for their preparation and medicines combining these compounds
AU606693B2 (en) * 1987-06-23 1991-02-14 Helopharm W. Petrik Gmbh & Co. Kg Aminopropanol derivatives of 3-(3-hydroxyphenyl)-1-propanone compounds, process for preparing same, and pharmaceutical compositions containing said compounds
AU606692B2 (en) * 1987-06-23 1991-02-14 Helopharm W. Petrik Gmbh & Co. Kg Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone compounds, process for preparing same, and pharmaceutical compositions containing said compounds

Also Published As

Publication number Publication date
DK368877A (da) 1978-02-22
JPS5325528A (en) 1978-03-09
GR59194B (en) 1977-11-25
ES461779A1 (es) 1978-12-16
DE2736106A1 (de) 1978-02-23
SE7709142L (sv) 1978-02-22
PT66890B (fr) 1979-01-25
NL7708845A (nl) 1978-02-23
DD132431A5 (de) 1978-09-27
PT66890A (fr) 1977-09-01
NO772887L (no) 1978-02-22

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Legal Events

Date Code Title Description
RE Withdrawal of published application