FR2351972A1 - Precurseurs d'acides heteroarylbenzoxepine-acetiques - Google Patents
Precurseurs d'acides heteroarylbenzoxepine-acetiquesInfo
- Publication number
- FR2351972A1 FR2351972A1 FR7715359A FR7715359A FR2351972A1 FR 2351972 A1 FR2351972 A1 FR 2351972A1 FR 7715359 A FR7715359 A FR 7715359A FR 7715359 A FR7715359 A FR 7715359A FR 2351972 A1 FR2351972 A1 FR 2351972A1
- Authority
- FR
- France
- Prior art keywords
- heteroarylbenzoxepine
- acetic acid
- acid precursors
- precursors
- acetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/607,926 US4025640A (en) | 1975-08-26 | 1975-08-26 | Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2351972A1 true FR2351972A1 (fr) | 1977-12-16 |
FR2351972B1 FR2351972B1 (fr) | 1981-12-24 |
Family
ID=24434282
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7625728A Granted FR2346004A1 (fr) | 1975-08-26 | 1976-08-25 | Acides heteroarylbenzoxepine-acetiques, leur procede de preparation et leurs applications |
FR7715359A Granted FR2351972A1 (fr) | 1975-08-26 | 1977-05-18 | Precurseurs d'acides heteroarylbenzoxepine-acetiques |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7625728A Granted FR2346004A1 (fr) | 1975-08-26 | 1976-08-25 | Acides heteroarylbenzoxepine-acetiques, leur procede de preparation et leurs applications |
Country Status (25)
Country | Link |
---|---|
US (7) | US4025640A (fr) |
JP (1) | JPS5227764A (fr) |
AT (1) | AT359505B (fr) |
AU (1) | AU504461B2 (fr) |
BE (1) | BE845551A (fr) |
CA (1) | CA1068275A (fr) |
CH (1) | CH624408A5 (fr) |
DE (1) | DE2637110C3 (fr) |
DK (1) | DK384576A (fr) |
ES (1) | ES450881A1 (fr) |
FI (1) | FI62093C (fr) |
FR (2) | FR2346004A1 (fr) |
GB (2) | GB1563841A (fr) |
GR (1) | GR60832B (fr) |
HU (2) | HU174164B (fr) |
IE (1) | IE43940B1 (fr) |
IL (2) | IL50347A (fr) |
IT (1) | IT1064977B (fr) |
LU (1) | LU75650A1 (fr) |
MX (1) | MX4236E (fr) |
NL (1) | NL7609292A (fr) |
NO (1) | NO145139C (fr) |
PT (1) | PT65513B (fr) |
SE (1) | SE430161B (fr) |
ZA (1) | ZA765112B (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4025640A (en) * | 1975-08-26 | 1977-05-24 | American Hoechst Corporation | Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof |
US4104280A (en) * | 1977-02-04 | 1978-08-01 | Syntex (U.S.A.) Inc. | Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives |
US4130654A (en) * | 1978-01-30 | 1978-12-19 | Syntex (U.S.A.) Inc. | Novel 4-(8X-6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-yl)-4-oxobutyric acids, methods of preparation, compositions and uses thereof |
JPS54115388A (en) * | 1978-03-01 | 1979-09-07 | Nippon Chemiphar Co Ltd | Acetic acid derivative and its preparation |
JPS54147304U (fr) * | 1978-04-04 | 1979-10-13 | ||
US4211877A (en) * | 1979-02-13 | 1980-07-08 | American Hoechst Corporation | Method of preparation of isopropyl 4,10-dihydro-10-oxothieno[3,2-c][1]benzoxepin-8-acetate |
DE3125374A1 (de) * | 1981-06-27 | 1983-01-13 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von heteroaryl- und dibenzoxepinalkansaeuren |
AU8509882A (en) * | 1981-06-30 | 1983-01-06 | Merck & Co., Inc. | Tricyclic derivatives of substituted pyrrole acids |
US4560701A (en) * | 1981-07-23 | 1985-12-24 | Hoechst-Roussel Pharmaceuticals Inc. | Oxothienobenzoxepins, medicinal use, and process for the preparation thereof |
US4496580A (en) * | 1981-07-23 | 1985-01-29 | Hoechst-Roussel Pharmaceuticals Inc. | Oxothienobenzoxepins |
US4751238A (en) * | 1983-03-10 | 1988-06-14 | Hoechst-Roussel Pharmaceuticals, Inc. | Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz[b,e]oxepins |
US4514411A (en) * | 1983-03-10 | 1985-04-30 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 4,10-dihydro-10-oxothieno benzoxepins |
EP0118867A3 (fr) * | 1983-03-10 | 1984-12-05 | Hoechst-Roussel Pharmaceuticals Incorporated | 4,10-Dihydro-10-oxothiénobenzoxépines substituées, méthode pour leur préparation, intermédiaires et leur utilisation comme médicaments |
US4477465A (en) * | 1983-03-10 | 1984-10-16 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 4,10-dihydro-10-oxothieno benzoxepins |
US5260319A (en) * | 1989-12-26 | 1993-11-09 | Hoechst-Roussel Pharmaceuticals Incorporated | Thienobenzoxepins and naphthothiophenes |
US5139796A (en) * | 1991-06-28 | 1992-08-18 | Wm. Wrigley Jr. Company | Tocopherol mixture for use as a mint oil antioxidant in chewing gum |
US5132121A (en) * | 1991-08-12 | 1992-07-21 | Wm. Wrigley Jr. Company | Gum base containing tocopherol |
US5200213A (en) * | 1991-08-12 | 1993-04-06 | Wm. Wrigley Jr. Company | Gum base containing tocopherol |
CA2450073C (fr) | 2001-07-25 | 2017-08-29 | Biomarin Pharmaceutical Inc. | Compositions et procedes de modulation du transport a travers la barriere hematho-encephalique |
CN102379684B (zh) | 2005-04-28 | 2014-11-19 | 普罗透斯数字保健公司 | 药物信息*** |
JP2010503710A (ja) | 2006-09-18 | 2010-02-04 | ラプトール ファーマシューティカル インコーポレイテッド | 受容体関連タンパク質(rap)結合体の投与による肝障害の処置 |
PT3395372T (pt) | 2009-02-20 | 2022-05-05 | Enhanx Biopharm Inc | Sistema de entrega de medicamentos à base de glutationa |
WO2010129819A2 (fr) | 2009-05-06 | 2010-11-11 | Laboratory Skin Care, Inc. | Compositions pour libération dermique comprenant des complexes principe actif-particule de phosphate de calcium et procédés d'utilisation associés |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH83A (fr) * | 1888-11-17 | 1889-01-10 | Fontainemelon Horlogerie | Perfectionnements apportés à la construction des montres de tous calibres |
CH469729A (de) * | 1963-08-31 | 1969-03-15 | Spofa Vereinigte Pharma Werke | Verfahren zur Herstellung von neuen 4,9-Dihydrothieno-(2,3-b)-benzo-(e)-thiepinderivaten |
US3883551A (en) * | 1969-08-25 | 1975-05-13 | Little Inc A | Thienobenzopyrans and thiopyranobenzopyrans |
US3888946A (en) * | 1971-03-17 | 1975-06-10 | Little Inc A | Pyrano benzopyrans |
US3960871A (en) * | 1971-12-27 | 1976-06-01 | Sharps Associates | Esters of thienobenzopyrans and thiopyranobenzopyrans |
US3991194A (en) * | 1971-12-27 | 1976-11-09 | Sharps Associates | Heterocyclic esters of benzopyranopyridines |
DK131631C (da) * | 1972-04-07 | 1976-01-12 | Sandoz Ag | Analogifremgangsmade til fremstilling af 4-oxo-benzo(4,5)cyclohepta(1,2-b)thiophen-2-eddikesyreforbindelser |
GB1403487A (en) * | 1972-07-21 | 1975-08-28 | Yoshitomi Pharmaceutical | Heterocyclic substituted alkanoic acids and derivatives |
US3825574A (en) * | 1972-12-04 | 1974-07-23 | Warner Lambert Co | Process for preparing substituted chromone-3-carbonitriles,carboxamides and carboxylic acids |
US3862143A (en) * | 1972-12-04 | 1975-01-21 | Warner Lambert Co | Substituted chromone-3-carbonitriles, carboxamides and carboxylic acids |
US3895034A (en) * | 1973-08-29 | 1975-07-15 | Sharps Ass | 1 OR 2-Mono and dialkyl substituted thienobenzopyrans |
US3946111A (en) * | 1973-08-29 | 1976-03-23 | Sharps Associates | Pharmaceutical compositions containing 1 or 2-mono and dialkyl substituted thienobenzopyrans and pharmacological uses thereof |
FR2242098B1 (fr) * | 1973-09-04 | 1978-07-28 | Yoshitomi Pharmaceutical | |
NO743186L (fr) * | 1973-09-13 | 1975-04-07 | Sandoz Ag | |
US3952025A (en) * | 1974-08-26 | 1976-04-20 | American Hoechst Corporation | Substituted 2-phenyl-4,6,7,8-tetrahydrofuro and 1,4,5,6,7,8-hexahydropyrrolo[3,2,-c]azepines |
US4025640A (en) * | 1975-08-26 | 1977-05-24 | American Hoechst Corporation | Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof |
US4028383A (en) * | 1975-09-08 | 1977-06-07 | Warner-Lambert Company | Indolopyrones having antiallergic activity |
-
1975
- 1975-08-26 US US05/607,926 patent/US4025640A/en not_active Expired - Lifetime
-
1976
- 1976-08-18 DE DE2637110A patent/DE2637110C3/de not_active Expired
- 1976-08-20 ES ES450881A patent/ES450881A1/es not_active Expired
- 1976-08-20 NL NL7609292A patent/NL7609292A/xx not_active Application Discontinuation
- 1976-08-23 CH CH1067076A patent/CH624408A5/de not_active IP Right Cessation
- 1976-08-24 LU LU75650A patent/LU75650A1/xx unknown
- 1976-08-24 GR GR51534A patent/GR60832B/el unknown
- 1976-08-24 IT IT26507/76A patent/IT1064977B/it active
- 1976-08-24 IL IL50347A patent/IL50347A/xx unknown
- 1976-08-24 FI FI762422A patent/FI62093C/fi not_active IP Right Cessation
- 1976-08-25 MX MX764855U patent/MX4236E/es unknown
- 1976-08-25 NO NO762929A patent/NO145139C/no unknown
- 1976-08-25 AT AT630876A patent/AT359505B/de not_active IP Right Cessation
- 1976-08-25 CA CA259,785A patent/CA1068275A/fr not_active Expired
- 1976-08-25 SE SE7609390A patent/SE430161B/xx unknown
- 1976-08-25 IE IE1895/76A patent/IE43940B1/en unknown
- 1976-08-25 ZA ZA765112A patent/ZA765112B/xx unknown
- 1976-08-25 AU AU17151/76A patent/AU504461B2/en not_active Expired
- 1976-08-25 DK DK384576A patent/DK384576A/da not_active Application Discontinuation
- 1976-08-25 FR FR7625728A patent/FR2346004A1/fr active Granted
- 1976-08-25 PT PT65513A patent/PT65513B/pt unknown
- 1976-08-26 HU HU76HO2082A patent/HU174164B/hu unknown
- 1976-08-26 HU HU76HO1923A patent/HU173465B/hu unknown
- 1976-08-26 GB GB35542/76A patent/GB1563841A/en not_active Expired
- 1976-08-26 BE BE170106A patent/BE845551A/fr not_active IP Right Cessation
- 1976-08-26 GB GB12883/79A patent/GB1563842A/en not_active Expired
- 1976-08-26 JP JP51101181A patent/JPS5227764A/ja active Pending
-
1977
- 1977-04-19 US US05/788,787 patent/US4107321A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,782 patent/US4124713A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,786 patent/US4117152A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,958 patent/US4107177A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,788 patent/US4101559A/en not_active Expired - Lifetime
- 1977-04-19 US US05/788,753 patent/US4081457A/en not_active Expired - Lifetime
- 1977-05-18 FR FR7715359A patent/FR2351972A1/fr active Granted
-
1979
- 1979-12-04 IL IL58864A patent/IL58864A0/xx unknown
Non-Patent Citations (2)
Title |
---|
CA1977 * |
EXBK/77 * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2351972A1 (fr) | Precurseurs d'acides heteroarylbenzoxepine-acetiques | |
BE827794A (fr) | Derives d'acides phenoxy-alcanoiques | |
BE826446A (fr) | Sels d'acides phenylalkandiques | |
FR2297968A1 (fr) | Structure d'escalier | |
BE845308A (fr) | Derives d'acides phenoxy-alkylcarboxyliques | |
FR2297713A1 (fr) | Procede d'introduction | |
FR2338948A1 (fr) | Acides diphosphonoalcanecarboxyliques | |
BE859781A (fr) | Acides pyrazol-1-yl-phenylacetiques | |
SE7603597L (sv) | Reduktionsmedel for staltillverkning | |
IT1060881B (it) | Preparazione di 3 fenossibenzaldeidi | |
BE844143A (fr) | N-amides w -disubstitues d'acides amino-alcanoiques | |
FR2314732A1 (fr) | Solution d'iodophore | |
FR2316931A1 (fr) | Derives d'acides dl- et 8 r-9-fluoro-prostadienoiques | |
FR2323392A1 (fr) | Esters d'acides furanose-o-pyridylcarboxyliques | |
JPS51100070A (ja) | 1*22benzoisochiazooruruinoseiho | |
BE846657A (fr) | 2,4,6-triiodo-anilides 3,5-disubstitues d'acides polyhydroxy-monobasiques | |
BE842998A (fr) | Preparation d'acides aromatiques | |
FR2298591A1 (fr) | Solution aque | |
SE7604287L (sv) | Deoxiklavulansyra | |
JPS51109263A (ja) | Kinzokusutoritsupuno 2 jokirisuritsutoseihinno makitorihoho | |
SU550363A1 (ru) | Полимерминеральный раствор | |
BE849090A (fr) | Element d'espacement | |
JPS51102355A (ja) | Shashinhaiekinifukumareruechirenjiamin 44 sakusannoshoriho | |
JPS51100053A (ja) | 1*44nafutarinjikarubonsanesuterunoseiho | |
BE825269A (fr) | Suspensions d'acides maleamiques |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |